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Chapter 02 - Neurons and Glia
Chapter 02 - Neurons and Glia

... that drive it. (Refer to PowerPoint slide 21.) Teaching Suggestion: Using Figure 2.18, explain anterograde transport and retrograde transport and describe the roles of kinesin and dynein. Discussion Point: Discuss the following case study in the classroom and explain how retrograde transport help wh ...
Nervous System
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... Electrochemical gradients: the sum of the chemical and electrical forces acting on a specific ion across the cell membrane ...
Internal structure of spinal cord
Internal structure of spinal cord

... especially. descending corticospinal fibers (their major target) – Tracts cells from Lamina IV, V, and VI are generally referred as nucleus proprius – Lamina 5 and 6 receives proprioceptive input AND sensory information relayed by lamina 4. These are the sites of origin of ascending projections to h ...
Final Exam Answers
Final Exam Answers

... channels from inactivation occurs A. after an additional 1 to 3 msec, even when the cell membrane potential remains depolarized. *B. 1 to 3 msec after the cell membrane potential has been hyperpolarized back to near the resting membrane potential. C. 50 to 100 msec after the cell membrane potential ...
How grid cells neurons encode rat position
How grid cells neurons encode rat position

... spatial activity patterns non-invasively. • High temporal and spatial resolution is desirable. • No single technology currently satisfies both of these requirements. • By combining data from different modalities, the shortcomings of individual techniques can be overcome. ...
PPT
PPT

...  Learning algorithm, or training method: method for deter mining weights of the connections  Activation function: function that produces an output b ased on the input values received by node ...
Lecture notes Neural Computation
Lecture notes Neural Computation

... They suck up the spilt over neuro-transmitters, and others provide myelin sheets around the axons of neurons. More important for us are the neurons. There are some 1011 neurons in a human brain. The basic anatomy of the neurons is shown in Fig. 1.4: Every neuron has a cell body, or soma, contains th ...
Interneurons and triadic circuitry of the thalamus
Interneurons and triadic circuitry of the thalamus

... nucleus or inferior collicular input to the medial geniculate nucleus) replaces the retinal input in this circuit. Less commonly, an F2 terminal is postsynaptic to a cholinergic terminal from the brainstem parabrachial region, and the same parabrachial axon (but not the same terminal) contacts the s ...
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molecular mechanisms of axonal regeneration in the central
molecular mechanisms of axonal regeneration in the central

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Spinal Cord – Gross Anatomy
Spinal Cord – Gross Anatomy

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Distinct or Gradually Changing Spatial and Nonspatial
Distinct or Gradually Changing Spatial and Nonspatial

... out a continuous theta oscillation. Moreover, the nature of theta oscillation in the bat’s dorsal hippocampus was intermittent (Ulanovsky and Moss, 2007), much like the intermittent theta reported by Royer et al. (2010) in the rat ventral hippocampus. The existence of place cells without continuous ...
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Group Redundancy Measures Reveal Redundancy Reduction in the
Group Redundancy Measures Reveal Redundancy Reduction in the

... representing more and more complex aspects of sensory inputs. The changes in representations of stimuli along the sensory pathway reflect the information processing performed by the system. Several computational principles that govern these changes were suggested, such as information maximization an ...
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On the nature of the BOLD fMRI contrast mechanism

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Lecture 22 clustering

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Auditory Nerve - Neurobiology of Hearing
Auditory Nerve - Neurobiology of Hearing

... auditory nerve, and its target the cochlear nucleus. The orientation of the cut is illustrated by the pink line in the drawing of the cat head (left). We learned about the relationship between these structures by inserting a dye-filled micropipette into the auditory nerve and making small injections ...
Brain Plasticity and Behavior
Brain Plasticity and Behavior

... draw from our studies. First, experience alters the brain, and it does so in an age-related manner. Second, both pre- and postnatal experience have such effects, and these effects are long-lasting and can influence not only brain structure but also adult behavior. Third, seemingly similar experience ...
Cortex
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A computational account for the ontogeny of mirror neurons via
A computational account for the ontogeny of mirror neurons via

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chapter 43 The Nervous System
chapter 43 The Nervous System

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neural circuitry approaches to understanding the pathophysiology

... of Parkinson’s disease, which was then viewed as a single neurotransmitter (e.g., dopamine) disease owing to a localized neuropathology (e.g., cell death in the substantia nigra). However, in recent years, these two general approaches have given way to neural circuitry-based models that reflect a fu ...
FIGURE LEGENDS FIGURE 46.1 Lateral viewof a human brain
FIGURE LEGENDS FIGURE 46.1 Lateral viewof a human brain

... its response. In the right panel the monkey executes the instructed saccade. The neural response remains high until after the eye movement. FIGURE 46.7 A salience representation can be viewed as an intermediate representation that interacts with multiple behavioral systems (visual, motor, cognitive ...
Structural Classification of the Nervous System
Structural Classification of the Nervous System

... The entry of calcium into the axon terminal causes porelike openings to form, releasing the transmitter ...
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Synaptic gating



Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic gating involves a mechanism of central control over neuronal output. It includes a sort of gatekeeper neuron, which has the ability to influence transmission of information to selected targets independently of the parts of the synapse upon which it exerts its action (see also neuromodulation).Bistable neurons have the ability to oscillate between a hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred to as up/down neurons. According to one model, this ability is linked to the presence of NMDA and AMPA glutamate receptors. External stimulation of the NMDA receptors is responsible for moving the neuron from the down state to the up state, while the stimulation of AMPA receptors allows the neuron to reach and surpass the threshold potential. Neurons that have this bistable ability have the potential to be gated because outside gatekeeper neurons can modulate the membrane potential of the gated neuron by selectively shifting them from the up state to the down state. Such mechanisms have been observed in the nucleus accumbens, with gatekeepers originating in the cortex, thalamus and basal ganglia.
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