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slides
slides

... Citric Acid Cycle (Kreb Cycle) – Oxydation of pyruvic acid to H+, eand CO2 (occurs in mitochondria) 3. The Q10 - The rate of respiration doubles when temperature rises 10 oC (18 oF) - Respiration can be reduced by lowering O2 and increasing CO2 ...
Chapter 8
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... • The reactant that an enzyme acts on is called the enzyme’s substrate • The enzyme binds to its substrate, forming an enzyme-substrate complex • The active site is the region on the enzyme where the substrate binds • Induced fit of a substrate brings chemical groups of the active site into position ...
NSC 207 - National Open University of Nigeria
NSC 207 - National Open University of Nigeria

... The glycolytic pathway has a dual role (i) It degrades glucose to generate ATP and (ii) It provides building blocks for synthetic reactions. The rate of conversion of glucose into pyruvate is regulated to meet these 2 major cellular needs. Enzymes catalyzing essentially irreversible reactions are po ...
Chapter 7 Carbohydrates: Nomenclature Monosaccharides
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... Note that for beta- D-glucose. All non-hydrogen atoms on the ring are in the equatorial position. That makes beta glucose more stable than alpha glucose, and the equilibrium mixture of the two contains more beta than alpha. Note we most commonly find glucose and other aldohexoses in the pyranose rin ...
Nonenzymatic glycolysis and pentose phosphate
Nonenzymatic glycolysis and pentose phosphate

... observed. For instance, Reynolds et al described the equilibrium between the three-carbon sugar phosphates dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P), in modern metabolism converted by triosephosphate isomerase (Reynolds et al, 1971). More recently, Breslow presented a ch ...
animals that survive without oxygen - Det Norske Videnskaps
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Lecture 6 - TCA cycle I - University of Lethbridge

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Title: Hormones of the Pancreas
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... unsaturated fatty acids. In comparison with the original oil, the new fatty acids have additional double carbon–carbon bonds, replacing what were once single bonds. This process could also be described as _____________. (a) isomerization (b) oxidation (c) reduction (d) protonation ...
Title: Hormones of the Pancreas
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Glycolysis



Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the high-energy compounds ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine dinucleotide).Glycolysis is a determined sequence of ten enzyme-catalyzed reactions. The intermediates provide entry points to glycolysis. For example, most monosaccharides, such as fructose and galactose, can be converted to one of these intermediates. The intermediates may also be directly useful. For example, the intermediate dihydroxyacetone phosphate (DHAP) is a source of the glycerol that combines with fatty acids to form fat.Glycolysis is an oxygen independent metabolic pathway, meaning that it does not use molecular oxygen (i.e. atmospheric oxygen) for any of its reactions. However the products of glycolysis (pyruvate and NADH + H+) are sometimes disposed of using atmospheric oxygen. When molecular oxygen is used in the disposal of the products of glycolysis the process is usually referred to as aerobic, whereas if the disposal uses no oxygen the process is said to be anaerobic. Thus, glycolysis occurs, with variations, in nearly all organisms, both aerobic and anaerobic. The wide occurrence of glycolysis indicates that it is one of the most ancient metabolic pathways. Indeed, the reactions that constitute glycolysis and its parallel pathway, the pentose phosphate pathway, occur metal-catalyzed under the oxygen-free conditions of the Archean oceans, also in the absence of enzymes. Glycolysis could thus have originated from chemical constraints of the prebiotic world.Glycolysis occurs in most organisms in the cytosol of the cell. The most common type of glycolysis is the Embden–Meyerhof–Parnas (EMP pathway), which was discovered by Gustav Embden, Otto Meyerhof, and Jakub Karol Parnas. Glycolysis also refers to other pathways, such as the Entner–Doudoroff pathway and various heterofermentative and homofermentative pathways. However, the discussion here will be limited to the Embden–Meyerhof–Parnas pathway.The entire glycolysis pathway can be separated into two phases: The Preparatory Phase – in which ATP is consumed and is hence also known as the investment phase The Pay Off Phase – in which ATP is produced.↑ ↑ 2.0 2.1 ↑ ↑ ↑ ↑ ↑ ↑
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