Science
... We found that specific hydrophobic motifs found in SIRT1 substrates such as PGC-1a and FOXO3a facilitate SIRT1 activation by STACs. A single amino acid in SIRT1, Glu230, located in a structured N-terminal domain, was critical for activation by all previously reported STAC scaffolds and a new class o ...
... We found that specific hydrophobic motifs found in SIRT1 substrates such as PGC-1a and FOXO3a facilitate SIRT1 activation by STACs. A single amino acid in SIRT1, Glu230, located in a structured N-terminal domain, was critical for activation by all previously reported STAC scaffolds and a new class o ...
Prediction of Folding, Stability and Structure of Proteins from Amino
... with an amide group (--NH2) and end with a carboxylate group (--COOH). In between these two groups is an _-carbon, C_. Bonded to the C_ are an R group and a hydrogen atom. The backbone of the amino acid sequence is formed by a linear combination of amino acids bonding together so that a repeated lin ...
... with an amide group (--NH2) and end with a carboxylate group (--COOH). In between these two groups is an _-carbon, C_. Bonded to the C_ are an R group and a hydrogen atom. The backbone of the amino acid sequence is formed by a linear combination of amino acids bonding together so that a repeated lin ...
Metabolic Responses to Cardiac Hypoxia
... when these precursors were present. The aminotransferase inhibitor, aminooxyacetate, reduced succinate production by hypoxic papillary muscles. This finding demonstrated a close relationship between transamination of amino acids and succinate production. In addition, it is suggested that anaerobic m ...
... when these precursors were present. The aminotransferase inhibitor, aminooxyacetate, reduced succinate production by hypoxic papillary muscles. This finding demonstrated a close relationship between transamination of amino acids and succinate production. In addition, it is suggested that anaerobic m ...
Lipase Specificity and Selectivity
... polymerization of D,D‐lactide. Two mutants, with about 90‐fold increase in activity as compared to the wild‐type enzyme, were created. Changing a glutamine into alanine accounted for this increase in both mutants by creating a larger space in the acyl donor po ...
... polymerization of D,D‐lactide. Two mutants, with about 90‐fold increase in activity as compared to the wild‐type enzyme, were created. Changing a glutamine into alanine accounted for this increase in both mutants by creating a larger space in the acyl donor po ...
Received June 19, 1964.
... nucleotides by the pathway proposed in the Introduction. The observed greater conversion of orotic acid than either aspartic or carbamyl aspartic acids to -RNA is predicted by its position in the metabolic sequence, although comparisons are somewhat difficult because only the DL-forms of the latter ...
... nucleotides by the pathway proposed in the Introduction. The observed greater conversion of orotic acid than either aspartic or carbamyl aspartic acids to -RNA is predicted by its position in the metabolic sequence, although comparisons are somewhat difficult because only the DL-forms of the latter ...
Canola Meal for Pig Feeding
... project work undertaken jointly by the Pork CRC and Australian Oilseeds Federation. This work was able to demonstrate that under typical processing conditions as used by GrainCorp Oilseeds, the effects of processing have a minimal impact upon meal quality. It is during more extreme or less controlle ...
... project work undertaken jointly by the Pork CRC and Australian Oilseeds Federation. This work was able to demonstrate that under typical processing conditions as used by GrainCorp Oilseeds, the effects of processing have a minimal impact upon meal quality. It is during more extreme or less controlle ...
Immunoblot Detection of Proteins That Contain Cysteine
... Prxs was identified in yeast (6) and mammals (7) and was named sulfiredoxin (Srx). Reduction by Srx is specific to 2-Cys Prxs; the sulfinic forms of Prx V and Prx VI are thus not reduced by Srx (8). Moreover, Srx acts on neither the sulfinic form of GAPDH nor DJ-1 (8). This specificity is due to the ...
... Prxs was identified in yeast (6) and mammals (7) and was named sulfiredoxin (Srx). Reduction by Srx is specific to 2-Cys Prxs; the sulfinic forms of Prx V and Prx VI are thus not reduced by Srx (8). Moreover, Srx acts on neither the sulfinic form of GAPDH nor DJ-1 (8). This specificity is due to the ...
Nutritional Aspects of Inborn Errors of Metabolism
... methylmalonic acidemia (MMA), and infantile tyrosinosis, the borderline between deficiency and excess is narrow, and monitoring is more difficult than in PKU. Low protein diets, in which total protein is restricted and replaced by nonprotein calories, are necessary in several diseases such as urea c ...
... methylmalonic acidemia (MMA), and infantile tyrosinosis, the borderline between deficiency and excess is narrow, and monitoring is more difficult than in PKU. Low protein diets, in which total protein is restricted and replaced by nonprotein calories, are necessary in several diseases such as urea c ...
Document
... f. Ligases: These are the enzymes catalysing the linking together of two compounds. 2. Describe the secondary structure of DNA. Ans. Secondary structure of DNA is explained by Watson and Crick. According to Watson and Crick model DNA exists as a double helix. Two strands of polynucleotides are antip ...
... f. Ligases: These are the enzymes catalysing the linking together of two compounds. 2. Describe the secondary structure of DNA. Ans. Secondary structure of DNA is explained by Watson and Crick. According to Watson and Crick model DNA exists as a double helix. Two strands of polynucleotides are antip ...
Targeting Acetyl-CoA Carboxylases: Small
... 1 [17, 68-72], natural ACC inhibitors are isolated from natural products, such as Soraphen A (WO03011867) from Sporangium cellulosum [73-75], avenaciolide (WO03094912 and JP035998) from Aspergillus avenaceus, chloroacetylated biotin (US6242610 and US6485941) from beans, egg yolks, and cauliflower [7 ...
... 1 [17, 68-72], natural ACC inhibitors are isolated from natural products, such as Soraphen A (WO03011867) from Sporangium cellulosum [73-75], avenaciolide (WO03094912 and JP035998) from Aspergillus avenaceus, chloroacetylated biotin (US6242610 and US6485941) from beans, egg yolks, and cauliflower [7 ...
Why should we study B12 and Folate? Deficiencies in both are still
... o Folate is transported as methyl-THF and only methionine synthase can use methyl-THF Methylmalonyl CoA Mutase Converts Methylmalonyl CoA that is generated during branched amino acid metabolism (among ...
... o Folate is transported as methyl-THF and only methionine synthase can use methyl-THF Methylmalonyl CoA Mutase Converts Methylmalonyl CoA that is generated during branched amino acid metabolism (among ...
PRACTICAL ORGANIC CHEMISTRY
... compounds known as osazone. Such compounds are used to identify the different types of carbohydrates by observing the crystallineform of the osazone under the microscope. Dissolve 0.2 g of the carbohydrate, 0.4g of phenylhydrazine hydrochloride and 0.6g of sod. acetate in 4 ml of water and dip the t ...
... compounds known as osazone. Such compounds are used to identify the different types of carbohydrates by observing the crystallineform of the osazone under the microscope. Dissolve 0.2 g of the carbohydrate, 0.4g of phenylhydrazine hydrochloride and 0.6g of sod. acetate in 4 ml of water and dip the t ...
Aromatic Amino Acids-Guanidinium Complexes through
... minima similar in energy but very different structurally. They found that the differences in stability were mainly a consequence of the different strength of the cation···π contact [21]. On the other hand, they have recently published the study of the interaction of guanidinium with Phe, Tyr and Trp ...
... minima similar in energy but very different structurally. They found that the differences in stability were mainly a consequence of the different strength of the cation···π contact [21]. On the other hand, they have recently published the study of the interaction of guanidinium with Phe, Tyr and Trp ...
Aromatic Amino Acids-Guanidinium Complexes through
... minima similar in energy but very different structurally. They found that the differences in stability were mainly a consequence of the different strength of the cation···π contact [21]. On the other hand, they have recently published the study of the interaction of guanidinium with Phe, Tyr and Trp ...
... minima similar in energy but very different structurally. They found that the differences in stability were mainly a consequence of the different strength of the cation···π contact [21]. On the other hand, they have recently published the study of the interaction of guanidinium with Phe, Tyr and Trp ...
Amino Acid Sequences and Evolutionary Relationships - Parkway C-2
... How do similarities in amino acid sequences of various species provide evidence for evolution? An important technique used in determining evolutionary relationships is the biochemical comparison of organisms. Organisms that are not similar in physical appearance may show similarity in amino acid seq ...
... How do similarities in amino acid sequences of various species provide evidence for evolution? An important technique used in determining evolutionary relationships is the biochemical comparison of organisms. Organisms that are not similar in physical appearance may show similarity in amino acid seq ...
Interactions between lactic and propionic acid bacteria
... ln Swiss-type cheese manufacture, thermophilic lactic acid bacteria (LAB), including Laetobaeillus helvetieus, Laetobaeillus delbrueekii subsp laetis and Streptoeoeeus thermophilus, are used as starters and degrade lactose to D and L lactate. Propionibacteria (PAB) th en metabolize lactate to propio ...
... ln Swiss-type cheese manufacture, thermophilic lactic acid bacteria (LAB), including Laetobaeillus helvetieus, Laetobaeillus delbrueekii subsp laetis and Streptoeoeeus thermophilus, are used as starters and degrade lactose to D and L lactate. Propionibacteria (PAB) th en metabolize lactate to propio ...
A Straightforward Route to Enantiopure Pyrrolizidines and
... Corporation extensively explored soluble Rh and Ru complexes, either with or without promoters, as homogeneous catalysts for the production of oxygenates [26-33], including methanol, ethanol, and especially ethylene glycol. The principal shortcoming of all homogeneous CO hydrogenation reactions is t ...
... Corporation extensively explored soluble Rh and Ru complexes, either with or without promoters, as homogeneous catalysts for the production of oxygenates [26-33], including methanol, ethanol, and especially ethylene glycol. The principal shortcoming of all homogeneous CO hydrogenation reactions is t ...
Russell, M.J. and Hall, A.J. 2006.
... the Hadean ocean, and H2 generated as ocean water oxidized ferrous iron during convection in the oceanic crust, was resolved by the onset of life. We suggest that this chemosynthetic life emerged within hydrothermal mounds produced by alkaline solutions of moderate temperature in the relative safety ...
... the Hadean ocean, and H2 generated as ocean water oxidized ferrous iron during convection in the oceanic crust, was resolved by the onset of life. We suggest that this chemosynthetic life emerged within hydrothermal mounds produced by alkaline solutions of moderate temperature in the relative safety ...
Seminario Glúcidos 3 y lípidos 1. Comente los mecanismos de
... of mitochondria which had been sedimented once in 10 volumes of 0.88 M sucrose as described above, and subjecting the suspension at this point to two or three preliminary sedimentations at low speed (2000 X g), each of 5 minutes duration. The main bulk of the mitochondria, now freed of red blood cel ...
... of mitochondria which had been sedimented once in 10 volumes of 0.88 M sucrose as described above, and subjecting the suspension at this point to two or three preliminary sedimentations at low speed (2000 X g), each of 5 minutes duration. The main bulk of the mitochondria, now freed of red blood cel ...
The Metabolism of Triglycerides by Spores of Penic
... showed considerable variation. Reproducible results were obtained by using 100-ml. medical flat bottles, sloped to give the maximum surface area of solution. Activation of spores Spores from 5-day cultures were harvested, washed and suspended in phosphate buffer (pH 6.5). These spores oxidized trioc ...
... showed considerable variation. Reproducible results were obtained by using 100-ml. medical flat bottles, sloped to give the maximum surface area of solution. Activation of spores Spores from 5-day cultures were harvested, washed and suspended in phosphate buffer (pH 6.5). These spores oxidized trioc ...
Aldehydes, Ketones and Carboxylic Acids
... In the previous Unit, you have studied organic compounds with functional groups containing carbonoxygen single bond. In this Unit, we will study about the organic compounds containing carbon-oxygen double bond (>C=O) called carbonyl group, which is one of the most important functional groups in orga ...
... In the previous Unit, you have studied organic compounds with functional groups containing carbonoxygen single bond. In this Unit, we will study about the organic compounds containing carbon-oxygen double bond (>C=O) called carbonyl group, which is one of the most important functional groups in orga ...
Docking of B-cell epitope antigen to specific hepatitis B antibody
... antigen and in understanding where important regions of an antigen are located in its three-dimensional structure. Therefore, mapping the interaction surface between antibody and antigen that bind each other is of outstanding interest in molecular immunology. Complementary to various experimental te ...
... antigen and in understanding where important regions of an antigen are located in its three-dimensional structure. Therefore, mapping the interaction surface between antibody and antigen that bind each other is of outstanding interest in molecular immunology. Complementary to various experimental te ...
Effects of monosulfuron-ester on metabolic processes of nitrogen
... Associate Editor: Jerri Zilli Keywords: Acetolactate synthase Amino acids Cyanobacteria Monosulfuron-ester ...
... Associate Editor: Jerri Zilli Keywords: Acetolactate synthase Amino acids Cyanobacteria Monosulfuron-ester ...