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Previously in Bio308
Previously in Bio308

... Biaxial Model of bipolar affective disorders: ‘Most simply, manic states are here understood as the clinical expression, at one point in time, of excessive synaptic neurochemical capacity within the primary affective system, and depressive states as the clinical expression of neurotransmitter deple ...
DNA - Moore Public Schools
DNA - Moore Public Schools

... • Point mutation – nitrogen base(A,T,C or G) in DNA sequence replaced with another. • This may not affect the protein being made. Because of the WOBBLE EFFECT. (3rd base) • Frame shift mutations – nitrogen base(A,T,C or G) is mistakenly inserted or deleted from the DNA sequence. • This almost always ...
USMLE Step 1 Web Prep — Medically Important Viruses, Part 1
USMLE Step 1 Web Prep — Medically Important Viruses, Part 1

DNA Puzzle
DNA Puzzle

... made a nucleotide, let’s talk learn about the types of nucleotides that can be made. 1. Figuring out which Bases fit each sugar Most bases can combine with either Ribose or De-Oxyribose, but this is not true for all bases. Try each base with both sugars. Record your results in the table below. Use a ...
DNA - hedrickbiology
DNA - hedrickbiology

... fork: the sites on DNA where separation and replication occur. ► DNA Helicase: the enzyme that “unzips” a molecule of DNA. Hydrogen bonds between the base pairs are broken and the two strands unwind. ► DNA Polymerase: enzyme that brings more nucleotides and also proof-reads each new DNA strand, help ...
Lesson Plan
Lesson Plan

DNA, RNA, and PROTEINS
DNA, RNA, and PROTEINS

... Glue in the middle that holds the ladder together? ____________ ...
Nucleic Acids What are they
Nucleic Acids What are they

...  Model proposed by Watson & Crick, 1953  Two sugar-phosphate strands, next to each other, but running in opposite directions.  Specific Hydrogen bonds occur among bases from one chain to the other: A---T ...
Name - EdWeb
Name - EdWeb

... 9. Blood cells use a protein called _______________________ to capture and carry oxygen. 10. When a gene is changed, it is said to be ______________________________________________ 11. A mutation in the hemoglobin gene cause what disorder? __________________________________ What is a Chromosome? 12. ...
Viruses
Viruses

... • Use infected cell to produce more viruses • Capsid: protein coat surrounding DNA/RNA core • bacteriophage – virus that infects bacteria ...
Newitt AP Biology DNA
Newitt AP Biology DNA

... can be copied in a cell in just a few hours, with very few errors  (1/10 billion nucleotides.   Bacteria ­ start replicating at a site called the origin,  opens up a replication "bubble."  DNA is built in both directions until done. Eukaryotes ­  100s­1000s of origins, forming bubbles that enlarge a ...
DNA - Madison County Schools
DNA - Madison County Schools

... Two identical copies of DNA result The process occurs: – in the nucleus – During the s-phase of the cell cycle ...
As a group, quietly discuss each question and agree
As a group, quietly discuss each question and agree

... Helicase, RNA polymerase, and DNA polymerase. Part A: During DNA replication, which enzyme breaks the hydrogen bonds allowing the DNA to separate? ...
DNA Replication
DNA Replication

... mRNA is created by making a complementary strand to the DNA (gene) mRNA leaves the nucleus and goes to the cytoplasm mRNA binds to a ribosome tRNA binds to specific amino acids in the cytoplasm tRNA carries amino acids to the site of protein synthesis (the ribosome) Translation occurs at the ribosom ...
DNA - Royal Society of Chemistry
DNA - Royal Society of Chemistry

... and regulating how much of each type of protein is made. A detailed discussion of DNA/RNA function and the fundamental processes of replication, transcription and translation can be found in any good textbook on molecular biology. However, the Watson-Crick model provides a mechanism by which DNA mol ...
DNA experiments exercise
DNA experiments exercise

... What do these data reveal about the ratios different bases? Watson and Crick used this information as one of their key insights into the double helix structure of DNA. ...
Lab Instructions - Translation Please
Lab Instructions - Translation Please

... 4. With the mRNA sequence she/he will go back to the group’s desk and the ribosomal student will write out the tRNA anti-codon sequence for the tRNA. 5. The tRNA student will go out to the cell (walls of the classroom) and will search out the correct anti-codon card and flip the card over revealing ...
DNA and Protein Synthesis
DNA and Protein Synthesis

... C A T • Errors sometimes occur (about 1 error/10,000 pairs) I • If a mismatch occurs, the DNA polymerase can backtrack, remove the incorrect nucleotide, and O replace it with the correct one. N ...
Study Guide for LS
Study Guide for LS

... molecules. When DNA copies itself it splits down the middle where the two bases meet. The bases on each side of the molecule can be used as a pattern for a new complementary side. ...
DNA
DNA

... the order of the bases in one strand determines the order of the bases in the other strand.  The bases on one side of the helix form ...
Final
Final

... The autosomal genes cinnabar and brown in Drosophila encode proteins required for eye pigments. When the recessive allele of the sex-linked white gene is homozygous or hemizygous, however, neither pigment is actually visible in the fly's eye. What is this relationship among different gene called? ...
Worksheet Lesson 5: The discovery of DNA`s
Worksheet Lesson 5: The discovery of DNA`s

... Worksheet Lesson 5: The discovery of DNA's structure We can't credit just one scientist with the discovery of the structure of DNA. It was the work of many different scientists who built on the work of others before them. In this activity you will be finding out about some of these scientists and th ...
Aim 24: How does DNA code for the production of proteins through
Aim 24: How does DNA code for the production of proteins through

... Aim 24: How does DNA code for the production of proteins through the process of translation? Recall: Protein synthesis begins with the transcription of DNA to mRNA (The RNA that is synthesized from a DNA molecule). This process occurs in the nucleus, allowing the mRNA strand to leave the nucleus wit ...
Chapter 3,
Chapter 3,

... Even though some students correctly synthesize a fluorescent cDNA probe complementary to mRNA for a particular yeast protein, they find that the probe does not attach to any portion of the yeast’s genome. Explain why the students’ probe does not work. The cDNA probe sequence spans a splice junction ...
CHAPTER 16 - HCC Learning Web
CHAPTER 16 - HCC Learning Web

... • Early in the 20th century, the identification of the molecules of inheritance loomed as a major challenge to biologists • When T. H. Morgan’s group showed that genes are located on chromosomes, the two components of chromosomes—DNA and protein—became candidates for the genetic material • The role ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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