embor2011116-sup-0001
... Our review aimed at evaluating the correlation between such experimental data and those estimated in silico by several algorithms. The algorithms are, however, different in the type of predictions they provide. Two of the predictive methods provide directly the change in the aggregation rate upon mu ...
... Our review aimed at evaluating the correlation between such experimental data and those estimated in silico by several algorithms. The algorithms are, however, different in the type of predictions they provide. Two of the predictive methods provide directly the change in the aggregation rate upon mu ...
Naturally occurring amino acids differentially influence the
... monolayers and their effects on host cells Natural amino acids usually present in the growth medium (RPMI 1640), together with the Pro analogue Hyp, were included in this study, except cysteine, due to its toxicity even at concentrations lower than those used for other amino acids (data not shown). ...
... monolayers and their effects on host cells Natural amino acids usually present in the growth medium (RPMI 1640), together with the Pro analogue Hyp, were included in this study, except cysteine, due to its toxicity even at concentrations lower than those used for other amino acids (data not shown). ...
an evaluation of probiotic potential of lactobacillus sp
... little clinical benefit. Production and quality control are not regulated as per the guidelines of probiotic products, but few products are likely to achieve the benefits identified in formal clinical trials. Even with better-characterized isolates, trial results can vary reflecting production and s ...
... little clinical benefit. Production and quality control are not regulated as per the guidelines of probiotic products, but few products are likely to achieve the benefits identified in formal clinical trials. Even with better-characterized isolates, trial results can vary reflecting production and s ...
A standard nomenclature for von Willebrand factor gene mutations
... The ISTH SSC factor VIII and IX subcommittee has already suggested a standard nomenclature for FVIII and IX gene mutations (10) and now suggest a nomenclature for VWF. A series of papers on proposed mutation nomenclature schemes for human genes have been published in Human Mutation produced by the " ...
... The ISTH SSC factor VIII and IX subcommittee has already suggested a standard nomenclature for FVIII and IX gene mutations (10) and now suggest a nomenclature for VWF. A series of papers on proposed mutation nomenclature schemes for human genes have been published in Human Mutation produced by the " ...
Direct organocatalytic enantioselective a-aminomethylation
... complexes.10 Recently, Shibasaki and Matsunaga,11 and Trost and co-workers12 developed di-nuclear zinc organometallic complexes as catalyst for the direct catalytic enantioselective Mannich-type reactions between hydroxyarylketones and preformed imines. In addition, Jørgensen and co-workers have dev ...
... complexes.10 Recently, Shibasaki and Matsunaga,11 and Trost and co-workers12 developed di-nuclear zinc organometallic complexes as catalyst for the direct catalytic enantioselective Mannich-type reactions between hydroxyarylketones and preformed imines. In addition, Jørgensen and co-workers have dev ...
Page 4 of 4 - Thermo Fisher Scientific
... 1 µl of SuperScript™ III RT (200 units/µl)* *If generating cDNA longer than 5 kb at temperatures above 50°C using a gene-specific primer or oligo(dT)20, the amount of SuperScript™ III RT may be raised to 400 U (2 µl) to increase yield. 4. Mix by pipetting gently up and down. If using random primers, ...
... 1 µl of SuperScript™ III RT (200 units/µl)* *If generating cDNA longer than 5 kb at temperatures above 50°C using a gene-specific primer or oligo(dT)20, the amount of SuperScript™ III RT may be raised to 400 U (2 µl) to increase yield. 4. Mix by pipetting gently up and down. If using random primers, ...
kinetic characterisation of catalysts for methanol synthesis
... catalyst called KATALCO which is the standard of Cu/ZnO/Al2O3. A new generation of catalysts also based on the copper catalyst is named APICO. Haldor Topsoe company produces CuO/ZnO/Al2O3 called MK-121 where the composition of the catalyst is: CuO (wt%) - 55; ZnO (wt%) 21-25; Al2O3 (wt%) 8-10; catal ...
... catalyst called KATALCO which is the standard of Cu/ZnO/Al2O3. A new generation of catalysts also based on the copper catalyst is named APICO. Haldor Topsoe company produces CuO/ZnO/Al2O3 called MK-121 where the composition of the catalyst is: CuO (wt%) - 55; ZnO (wt%) 21-25; Al2O3 (wt%) 8-10; catal ...
PowerPoint 演示文稿
... The psiRNA has been optimized so that analysis of only 5 white transformed colonies is sufficient to obtain the expected siRNA. ...
... The psiRNA has been optimized so that analysis of only 5 white transformed colonies is sufficient to obtain the expected siRNA. ...
The reaction pathways of hydrogen peroxide in
... hydroxyl radicals created by the Fenton reaction and their potential to oxidize the disulfide bridge of small peptides. Based on the reduction potential, which is an indicator for the oxidizability by radicals, disulfide bridges in a peptide or protein are more facile targets for radical attack than ...
... hydroxyl radicals created by the Fenton reaction and their potential to oxidize the disulfide bridge of small peptides. Based on the reduction potential, which is an indicator for the oxidizability by radicals, disulfide bridges in a peptide or protein are more facile targets for radical attack than ...
Journal of Otology & Rhinology
... cephalosporin has been recommended in the treatment of acute bacterial suppurative parotitis [1,4,5]. Our previous practice was to treat hospitalized patients with parotitis empirically with intravenous ampicillin/sulbactam or clindamycin while awaiting cultures and sensitivities in order to cover f ...
... cephalosporin has been recommended in the treatment of acute bacterial suppurative parotitis [1,4,5]. Our previous practice was to treat hospitalized patients with parotitis empirically with intravenous ampicillin/sulbactam or clindamycin while awaiting cultures and sensitivities in order to cover f ...
Interdependence, Reflexivity, Fidelity, Impedance Matching
... By the time protein folding organizes amino acid side chains into a functional active site, genetic information has been irreversibly transformed. Any molecular machine charged with reversing translation by unfolding, then “reading” the sequence of a protein would require shuttling ...
... By the time protein folding organizes amino acid side chains into a functional active site, genetic information has been irreversibly transformed. Any molecular machine charged with reversing translation by unfolding, then “reading” the sequence of a protein would require shuttling ...
Interdependence, Reflexivity, Fidelity, Impedance Matching
... By the time protein folding organizes amino acid side chains into a functional active site, genetic information has been irreversibly transformed. Any molecular machine charged with reversing translation by unfolding, then “reading” the sequence of a protein would require shuttling ...
... By the time protein folding organizes amino acid side chains into a functional active site, genetic information has been irreversibly transformed. Any molecular machine charged with reversing translation by unfolding, then “reading” the sequence of a protein would require shuttling ...
Affinity Chromatography
... attachment of ligands to spacer arms already present on the pre-activated affinity matrix, whereas the ‘pre-assembly’ approach uses conventional organic chemistry to modify the ligand with a suitably derivatized spacer arm, after which the whole assembly is coupled to the matrix. The solid-phase ass ...
... attachment of ligands to spacer arms already present on the pre-activated affinity matrix, whereas the ‘pre-assembly’ approach uses conventional organic chemistry to modify the ligand with a suitably derivatized spacer arm, after which the whole assembly is coupled to the matrix. The solid-phase ass ...
Acid derivatives
... • Acid Halides: The acyl group is named first, followed by the halogen name as a separate word. e.g. CH3CH2COCl is propanoyl chloride (or propionyl chloride). • Anhydrides: The name of the related acid(s) is used first, followed by the separate word "anhydride". e.g. (CH3(CH2)2CO)2O is butanoic anhy ...
... • Acid Halides: The acyl group is named first, followed by the halogen name as a separate word. e.g. CH3CH2COCl is propanoyl chloride (or propionyl chloride). • Anhydrides: The name of the related acid(s) is used first, followed by the separate word "anhydride". e.g. (CH3(CH2)2CO)2O is butanoic anhy ...
Discotic Bimetallomesogens: Building Blocks for the Formation of
... Coenzyme B12is an obligatory cofactor in a remarkable series of 12 enzyme-catalyzed rearrangement reactions.' Of these, the three-carbon skeleton rearrangements in the series have been particularly intriguing because of the lack of precedent for such transformations among organic reactions. The rear ...
... Coenzyme B12is an obligatory cofactor in a remarkable series of 12 enzyme-catalyzed rearrangement reactions.' Of these, the three-carbon skeleton rearrangements in the series have been particularly intriguing because of the lack of precedent for such transformations among organic reactions. The rear ...
VITA - Trace: Tennessee Research and Creative Exchange
... that strong σ-donor mono-, bi-, and tridentate ligands can be used to stabilize the metal ligand multiple bond (Figure 1.1A-C, respectively).10 In one example by Peters, it is found that the iron trisphosphinoborate complex (Figure 1.1C) can even activate an organic azide, however, the resulting imi ...
... that strong σ-donor mono-, bi-, and tridentate ligands can be used to stabilize the metal ligand multiple bond (Figure 1.1A-C, respectively).10 In one example by Peters, it is found that the iron trisphosphinoborate complex (Figure 1.1C) can even activate an organic azide, however, the resulting imi ...
4 - EMD Millipore
... Aminoglycosides, such as kanamycin: irreversibly inhibit protein synthesis following their binding to the 30S subunit of the bacterial ribosome. Disruption in protein synthesis by aminoglycosides occurs by three different modes: (a) by interfering with the initiation complex; (b) by inducing a misre ...
... Aminoglycosides, such as kanamycin: irreversibly inhibit protein synthesis following their binding to the 30S subunit of the bacterial ribosome. Disruption in protein synthesis by aminoglycosides occurs by three different modes: (a) by interfering with the initiation complex; (b) by inducing a misre ...
4 - Merck Millipore
... Aminoglycosides, such as kanamycin: irreversibly inhibit protein synthesis following their binding to the 30S subunit of the bacterial ribosome. Disruption in protein synthesis by aminoglycosides occurs by three different modes: (a) by interfering with the initiation complex; (b) by inducing a misre ...
... Aminoglycosides, such as kanamycin: irreversibly inhibit protein synthesis following their binding to the 30S subunit of the bacterial ribosome. Disruption in protein synthesis by aminoglycosides occurs by three different modes: (a) by interfering with the initiation complex; (b) by inducing a misre ...
74 CHAPTER-IV "LEAD (IV) ACETATE OXIDATIONS"
... oxidation of sugars with emphasis on glycol cleavage. 5 A number of useful general reviews on lead (IV) acetate have appeared. Fieser and Fieser6 have discussed the uses of lead (IV) acetate in a broad range of of synthetic processes, while Aylward7 has reviewed the general behaviour of lead (IV) ac ...
... oxidation of sugars with emphasis on glycol cleavage. 5 A number of useful general reviews on lead (IV) acetate have appeared. Fieser and Fieser6 have discussed the uses of lead (IV) acetate in a broad range of of synthetic processes, while Aylward7 has reviewed the general behaviour of lead (IV) ac ...
HUMAN PRIMARY CELLS RNA PRODUCTS Total RNA
... allows us to observe the 18s and 28s ribosomal RNA bands, which are another indicator of good RNA quality. Q. Why does my RNA product come in DEPC-treated water? A. AllCells stores and ships RNA products in DEPC-treated water which is nuclease-free, and can maintain quality and integrity of the RNA ...
... allows us to observe the 18s and 28s ribosomal RNA bands, which are another indicator of good RNA quality. Q. Why does my RNA product come in DEPC-treated water? A. AllCells stores and ships RNA products in DEPC-treated water which is nuclease-free, and can maintain quality and integrity of the RNA ...
Bottromycin
Bottromycin is a macrocyclic peptide with antibiotic activity. It was first discovered in 1957 as a natural product isolated from Streptomyces bottropensis. It has been shown to inhibit methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE) among other Gram-positive bacteria and mycoplasma. Bottromycin is structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic.Bottromycin binds to the A site of the ribosome and blocks the binding of aminoacyl-tRNA, therefore inhibiting bacterial protein synthesis. Although bottromycin exhibits antibacterial activity in vitro, it has not yet been developed as a clinical antibiotic, potentially due to its poor stability in blood plasma. To increase its stability in vivo, some bottromycin derivatives have been explored.The structure of bottromycin contains a macrocyclic amidine as well as a thiazole ring. The absolute stereochemistry at several chiral centers has been determined as of 2009. In 2012, a three-dimensional solution structure of bottromycin was published. The solution structure revealed that several methyl groups are on the same face of the structure.Bottromycin falls within the ribosomally synthesized and post-translationally modified peptide class of natural product.