Learning Objectives
... • However, semi-structured interviews in which patients are asked a largely predetermined series of qu_____________s do have good reliability and validity. Two of the most used semi-structured interviews for depression are the Structured Clinical Interview for DSM-IVPatient Version (SCID-I/P) and th ...
... • However, semi-structured interviews in which patients are asked a largely predetermined series of qu_____________s do have good reliability and validity. Two of the most used semi-structured interviews for depression are the Structured Clinical Interview for DSM-IVPatient Version (SCID-I/P) and th ...
The role of Cdx genes in the mammalian gut
... endoderm but appears at postsomite stages just before transition of the multilayered intestinal endoderm to a single layered epithelium at 14 days post coitum (dpc).6 Cdx4 is expressed in the earliest hindgut invagination7 but little is known of its distribution after 10 dpc. It is important to note ...
... endoderm but appears at postsomite stages just before transition of the multilayered intestinal endoderm to a single layered epithelium at 14 days post coitum (dpc).6 Cdx4 is expressed in the earliest hindgut invagination7 but little is known of its distribution after 10 dpc. It is important to note ...
Conclusions Synapsin IIa is expressed in the brain of adult zebrafish
... •Because zebrafish are now being increasingly used as a genetic model and to model a variety of human diseases, we focused our studies on the cloning and characterization of zebrafish synapsin IIa. ...
... •Because zebrafish are now being increasingly used as a genetic model and to model a variety of human diseases, we focused our studies on the cloning and characterization of zebrafish synapsin IIa. ...
Respondents` report of a clinician-diagnosed depression in health
... depression in middle-aged and older adults [1]. These findings suggest that there are substantial differences between DSM-IV-based major depression and a cliniciandiagnosed depression and, as a consequence, that the presence of major depression may not be inferred with accuracy from the respondent’s ...
... depression in middle-aged and older adults [1]. These findings suggest that there are substantial differences between DSM-IV-based major depression and a cliniciandiagnosed depression and, as a consequence, that the presence of major depression may not be inferred with accuracy from the respondent’s ...
Supplementary Figure 1. Generation of IDH2 mutant mice. (A
... Supplementary Figure 4. Reduced lipogenesis and stimulation of thermogenesis in adipose tissues of IDH2-deficient mice on a normal diet. (A) Quantifications of lipogenesis signal in sections of visceral WAT from wild-type and IDH2-/- mice. Quantifications of the levels of p53 and lipogenic protein ...
... Supplementary Figure 4. Reduced lipogenesis and stimulation of thermogenesis in adipose tissues of IDH2-deficient mice on a normal diet. (A) Quantifications of lipogenesis signal in sections of visceral WAT from wild-type and IDH2-/- mice. Quantifications of the levels of p53 and lipogenic protein ...
The role of Cdx genes in the mammalian gut
... endoderm but appears at postsomite stages just before transition of the multilayered intestinal endoderm to a single layered epithelium at 14 days post coitum (dpc).6 Cdx4 is expressed in the earliest hindgut invagination7 but little is known of its distribution after 10 dpc. It is important to note ...
... endoderm but appears at postsomite stages just before transition of the multilayered intestinal endoderm to a single layered epithelium at 14 days post coitum (dpc).6 Cdx4 is expressed in the earliest hindgut invagination7 but little is known of its distribution after 10 dpc. It is important to note ...
Epigenetics: Histone Modification III
... Paper to discuss Thursday (Sept.25th) Ooi, S.K., Qiu, C., Bernstein, E., Li, K., Jia, D., Yang, Z., Erdjument-Bromage, H., Tempst, P., Lin, S.P., Allis, C.D., Cheng, X., and Bestor, T.H. (2007). DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 448, 714-717. ...
... Paper to discuss Thursday (Sept.25th) Ooi, S.K., Qiu, C., Bernstein, E., Li, K., Jia, D., Yang, Z., Erdjument-Bromage, H., Tempst, P., Lin, S.P., Allis, C.D., Cheng, X., and Bestor, T.H. (2007). DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 448, 714-717. ...
journals - the biopsychology research group
... associated with ADHD. This was not replicated in more recent studies. Using data from a large multicenter study we examined the overall and gene specific parent of origin effect in 554 independent SNPs across 47 genes. Transmission disequilibrium and explicit parent of origin test were performed usi ...
... associated with ADHD. This was not replicated in more recent studies. Using data from a large multicenter study we examined the overall and gene specific parent of origin effect in 554 independent SNPs across 47 genes. Transmission disequilibrium and explicit parent of origin test were performed usi ...
When epigenetics meets alternative splicing: the roles of DNA
... in gene structure and to determine whether these changes are related to the splicing process. GC content architecture on the exon–intron structure has changed during evolution, especially during the transition from cold- to warmblooded organisms. The ancestral genome had short introns of low GC cont ...
... in gene structure and to determine whether these changes are related to the splicing process. GC content architecture on the exon–intron structure has changed during evolution, especially during the transition from cold- to warmblooded organisms. The ancestral genome had short introns of low GC cont ...
zChap12_140901 - Online Open Genetics
... The three-spined stickleback (Figure 12.11) provides an example of natural selection of a mutation in a cis-regulatory element. This fish occurs in two forms: (1) populations that inhabit deep, open water and have a spiny pelvic fin that deters larger predator fish from feeding on them; (2) populati ...
... The three-spined stickleback (Figure 12.11) provides an example of natural selection of a mutation in a cis-regulatory element. This fish occurs in two forms: (1) populations that inhabit deep, open water and have a spiny pelvic fin that deters larger predator fish from feeding on them; (2) populati ...
FnrP interactions with the Pasteurella haemolytica leukotoxin promoter
... (SA = 27 029.6, S.D. = 9482.7) was not signi¢cantly di¡erent than production by the pBluescript II KS(+) (Stratagene) control (SA = 16 540.8, S.D. = 9300.5). However, FnrP* (pMJU6) induced a signi¢cant increase (P 6 0.0001) in L-galactosidase activity (SA = 83 995.5, S.D. = 23 551.6) compared to the ...
... (SA = 27 029.6, S.D. = 9482.7) was not signi¢cantly di¡erent than production by the pBluescript II KS(+) (Stratagene) control (SA = 16 540.8, S.D. = 9300.5). However, FnrP* (pMJU6) induced a signi¢cant increase (P 6 0.0001) in L-galactosidase activity (SA = 83 995.5, S.D. = 23 551.6) compared to the ...
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... The transgenic mouse lines with mouse prosaposin promoter deletion constructs were 234Luc, 310Luc, 2400Luc, and 2400DLuc (Fig 1A). The tissue specific expression pattern of promoter deletion constructs was reported previously (Sun et al., 2000). The expression pattern for each construct was same amo ...
... The transgenic mouse lines with mouse prosaposin promoter deletion constructs were 234Luc, 310Luc, 2400Luc, and 2400DLuc (Fig 1A). The tissue specific expression pattern of promoter deletion constructs was reported previously (Sun et al., 2000). The expression pattern for each construct was same amo ...
Chromatin-Remodeling and Memory Factors
... Technology, ETH Center, 8092 Zurich, Switzerland (L.H., W.G.) The establishment and heritable maintenance of specific epigenetic states that lead to differential gene expression are crucial for cell differentiation and development. Over the past few years, it has become apparent that epigenetic cont ...
... Technology, ETH Center, 8092 Zurich, Switzerland (L.H., W.G.) The establishment and heritable maintenance of specific epigenetic states that lead to differential gene expression are crucial for cell differentiation and development. Over the past few years, it has become apparent that epigenetic cont ...
Allele- and parent-of-origin-specific effects on expression of the
... 2009), while ASE is common in non-imprinted loci throughout the genome (Tycko, 2010). Our results are consistent with those from other studies in humans (Locke et al., 2015), in which the KCNJ11 gene was found to be in allelic imbalance in beta cells. Even though this pattern is consistent between b ...
... 2009), while ASE is common in non-imprinted loci throughout the genome (Tycko, 2010). Our results are consistent with those from other studies in humans (Locke et al., 2015), in which the KCNJ11 gene was found to be in allelic imbalance in beta cells. Even though this pattern is consistent between b ...
Accepted Version - CSIRO Research Publications Repository
... cycle regulator Swm1/Apc13. In wild type, the BNS gene is normally expressed and not methylated (Figure 1). However, in a self-pollinated ddm1 mutant, the BNS gene is methylated and stochastically silenced (Figure 1), indicating that bns is a loss of function epigenetic mutant. The BNS gene is flank ...
... cycle regulator Swm1/Apc13. In wild type, the BNS gene is normally expressed and not methylated (Figure 1). However, in a self-pollinated ddm1 mutant, the BNS gene is methylated and stochastically silenced (Figure 1), indicating that bns is a loss of function epigenetic mutant. The BNS gene is flank ...
Expression systems for industrial Gram
... addition and only repression by glucose, not by other rapidly metabolizable compounds, was observed. This versatile system is not only suitable for fundamental studies aimed at comparing expression efficiencies but may also have potential for further applications, since it may be used in other, indu ...
... addition and only repression by glucose, not by other rapidly metabolizable compounds, was observed. This versatile system is not only suitable for fundamental studies aimed at comparing expression efficiencies but may also have potential for further applications, since it may be used in other, indu ...
Full Text - American Diabetes Association
... and secreting serotonin, including both isoforms of the serotonin synthetic enzyme tryptophan hydroxylase and the archetypal serotonergic transcription factor Pet1. As in serotonergic neurons, Pet1 expression in islets required homeodomain transcription factor Nkx2.2 but not Nkx6.1. In b-cells, Pet1 ...
... and secreting serotonin, including both isoforms of the serotonin synthetic enzyme tryptophan hydroxylase and the archetypal serotonergic transcription factor Pet1. As in serotonergic neurons, Pet1 expression in islets required homeodomain transcription factor Nkx2.2 but not Nkx6.1. In b-cells, Pet1 ...
Parental Methamphetamine Exposure Affects Offspring`s Behavior and
... Light/dark box:Maternally influenced phenotye (dependent on dam treatment (“METH induced”) and sexually dimorphic ...
... Light/dark box:Maternally influenced phenotye (dependent on dam treatment (“METH induced”) and sexually dimorphic ...