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... therefore should be endowed with a broad host-range promoter element. The well characterized lac promoter (Plac) of Escherichia coli has been shown to drive expression of cloned genes in a wide variety of Proteobacteria. Such an expression can be constitutive or regulated depending on the absence or ...
... therefore should be endowed with a broad host-range promoter element. The well characterized lac promoter (Plac) of Escherichia coli has been shown to drive expression of cloned genes in a wide variety of Proteobacteria. Such an expression can be constitutive or regulated depending on the absence or ...
supplemental figure legend and Materials and Methods
... experimental conditions. For example, 72% of genes change as much or more than CCND1 under androgen modulation, with KLK3 changing the most. (B) For 7 patients with locally advanced or metastatic prostate cancer from the GenTax study, CCND1, CDKN2A, and RB1 were not significantly changed by ADT in R ...
... experimental conditions. For example, 72% of genes change as much or more than CCND1 under androgen modulation, with KLK3 changing the most. (B) For 7 patients with locally advanced or metastatic prostate cancer from the GenTax study, CCND1, CDKN2A, and RB1 were not significantly changed by ADT in R ...
Bacillus Subtilis Expression Vectors
... Among them, Bacillus subtilis has been developed as an attractive host because of several reasons: (i) It is non-pathogenic and is considered as a GRAS organism (generally regarded as safe); (ii) it has no significant bias in codon usage; (iii) it is capable of secreting functional extracellular pro ...
... Among them, Bacillus subtilis has been developed as an attractive host because of several reasons: (i) It is non-pathogenic and is considered as a GRAS organism (generally regarded as safe); (ii) it has no significant bias in codon usage; (iii) it is capable of secreting functional extracellular pro ...
Evidence, Mechanisms and Models for the Inheritance of Acquired
... those involving DNA-protein interactions. For example, Groudine & Weintraub (1982) proposed that protein subunits are symmetrically bound to the two DNA strands, and that after replication, the parental strand retains the bound protein subunits; the semi-bound state of the duplex is then a preferent ...
... those involving DNA-protein interactions. For example, Groudine & Weintraub (1982) proposed that protein subunits are symmetrically bound to the two DNA strands, and that after replication, the parental strand retains the bound protein subunits; the semi-bound state of the duplex is then a preferent ...
Alisch RS, Wang T, Chopra P, Visootsak J, Conneely KN, Warren ST . Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1 locus. BMC Med Genet. 2013 Jan 29;14:18. doi: 10.1186/1471-2350-14-18.
... regions: 1500 base pairs of a transcription start site; 200 base pairs of a transcription start site; the first exon of a gene; the “30UTR” of a gene; the “50UTR” of a gene; a CpG Island; the “N_Shore” or “S_Shore” of a CpG island; or near a CGG trinucleotide repeat containing at least 8 consecutive ...
... regions: 1500 base pairs of a transcription start site; 200 base pairs of a transcription start site; the first exon of a gene; the “30UTR” of a gene; the “50UTR” of a gene; a CpG Island; the “N_Shore” or “S_Shore” of a CpG island; or near a CGG trinucleotide repeat containing at least 8 consecutive ...
HbF inducers
... ● Some studies have been carried out using valproic acid, a compound related to short fatty acid derivatives, reported increased HbF levels ...
... ● Some studies have been carried out using valproic acid, a compound related to short fatty acid derivatives, reported increased HbF levels ...
HIGH-INTENSITY ENDURANCE EXERCISE INCREASES MORE
... Exercise with Blood Flow Restriction (LI-EE+BFR), High-Intensity Endurance Exercise (HI-EE) and HighIntensity Resistance Exercise (HI-RE). Hypothesis: we expect to find similar responses to PGC-1α and other genes related to mitochondrial biogenesis, between LI-EE+BFR and HI-EE, and also similar resp ...
... Exercise with Blood Flow Restriction (LI-EE+BFR), High-Intensity Endurance Exercise (HI-EE) and HighIntensity Resistance Exercise (HI-RE). Hypothesis: we expect to find similar responses to PGC-1α and other genes related to mitochondrial biogenesis, between LI-EE+BFR and HI-EE, and also similar resp ...
Mood and Emotion in Major Depression
... emotional reactions? Circumstantial evidence suggests it does. From early psychoanalytic formulations of depression to contemporary cognitive conceptualizations, depression scholars have noted an increased expression of negative thoughts and feelings in this disorder. Depressed persons’ increased re ...
... emotional reactions? Circumstantial evidence suggests it does. From early psychoanalytic formulations of depression to contemporary cognitive conceptualizations, depression scholars have noted an increased expression of negative thoughts and feelings in this disorder. Depressed persons’ increased re ...
A series of promoters for constitutive expression of heterologous
... in YE medium containing intrinsic thiamine, which is commonly used for yeast cell culture. Therefore, this property of the nmt1 promoter may limit the area of research in some cases. In addition to these inducible promoters, the adh1 promoter has been used in a number of expression vectors, and its ...
... in YE medium containing intrinsic thiamine, which is commonly used for yeast cell culture. Therefore, this property of the nmt1 promoter may limit the area of research in some cases. In addition to these inducible promoters, the adh1 promoter has been used in a number of expression vectors, and its ...
persistent depressive disorder (dysthymia)
... The cause or causes of major depressive disorder and dysthymia are unknown, but both are probably the result of a complex interplay between biology, genetics, environment, and personality. In simpler terms, someone is born with a susceptibility to major depressive disorder or dysthymia and the dise ...
... The cause or causes of major depressive disorder and dysthymia are unknown, but both are probably the result of a complex interplay between biology, genetics, environment, and personality. In simpler terms, someone is born with a susceptibility to major depressive disorder or dysthymia and the dise ...
Depressive disorders include disruptive mood
... The cause or causes of major depressive disorder and dysthymia are unknown, but both are probably the result of a complex interplay between biology, genetics, environment, and personality. In simpler terms, someone is born with a susceptibility to major depressive disorder or dysthymia and the dise ...
... The cause or causes of major depressive disorder and dysthymia are unknown, but both are probably the result of a complex interplay between biology, genetics, environment, and personality. In simpler terms, someone is born with a susceptibility to major depressive disorder or dysthymia and the dise ...
The Epigenetics of Non
... As with miRNAs there are many subclasses of siRNAs that can be processed either as sense–antisense pairs (e.g. bidirectional promoter produced; Fig. 4.1 – siRNA pathway A), or as double-stranded transcripts which are subsequently cleaved by Dicer (Fig. 4.1 – siRNA pathway B) [25]. siRNA-based mechan ...
... As with miRNAs there are many subclasses of siRNAs that can be processed either as sense–antisense pairs (e.g. bidirectional promoter produced; Fig. 4.1 – siRNA pathway A), or as double-stranded transcripts which are subsequently cleaved by Dicer (Fig. 4.1 – siRNA pathway B) [25]. siRNA-based mechan ...
Chapter 4. The Epigenetics of Non
... As with miRNAs there are many subclasses of siRNAs that can be processed either as sense–antisense pairs (e.g. bidirectional promoter produced; Fig. 4.1 – siRNA pathway A), or as double-stranded transcripts which are subsequently cleaved by Dicer (Fig. 4.1 – siRNA pathway B) [25]. siRNA-based mechan ...
... As with miRNAs there are many subclasses of siRNAs that can be processed either as sense–antisense pairs (e.g. bidirectional promoter produced; Fig. 4.1 – siRNA pathway A), or as double-stranded transcripts which are subsequently cleaved by Dicer (Fig. 4.1 – siRNA pathway B) [25]. siRNA-based mechan ...
Text S1 unc-46 The unc-46 gene encodes a protein required for the
... drives strong and consistent expression in SDQR/L, same two neurons in which weak and inconsistent expression of the C. brenneri CRE is also seen. This latter cis element was active in the intestine (at levels that were much brighter than the background commonly seen with GFP transgenes), as well as ...
... drives strong and consistent expression in SDQR/L, same two neurons in which weak and inconsistent expression of the C. brenneri CRE is also seen. This latter cis element was active in the intestine (at levels that were much brighter than the background commonly seen with GFP transgenes), as well as ...
unfolded protein response is activated in the hearts of
... different antibody treatments to identify when the reduction of CSQ2 begins, to unveil the mechanism involved in the reduction of CSQ2 and to verify whether other proteins are affected by the presence of the mutated protein. The results of this study showed that mutated CSQ2 levels decreased soon afte ...
... different antibody treatments to identify when the reduction of CSQ2 begins, to unveil the mechanism involved in the reduction of CSQ2 and to verify whether other proteins are affected by the presence of the mutated protein. The results of this study showed that mutated CSQ2 levels decreased soon afte ...
to the PDF file. - Romanian Journal of Legal Medicine
... investigations. Traditionally, the majority of evidence on determinants of criminal behavior is contributed by environmental data. In the past two decades, a growing body of research in the fields of neurobiology and genetics has immensely enriched our understanding of the topic. This paper provides ...
... investigations. Traditionally, the majority of evidence on determinants of criminal behavior is contributed by environmental data. In the past two decades, a growing body of research in the fields of neurobiology and genetics has immensely enriched our understanding of the topic. This paper provides ...
William’s syndrome: gene expression is related to ORIGINAL ARTICLE
... As an approach toward understanding the role of the deleted genes in WS, we have characterized WS subjects according to genetic, social/ emotional, neurocognitive, neurophysiological and neuroanatomical features. Previous work from this laboratory also used molecular cytogenetic, microsatellite and ...
... As an approach toward understanding the role of the deleted genes in WS, we have characterized WS subjects according to genetic, social/ emotional, neurocognitive, neurophysiological and neuroanatomical features. Previous work from this laboratory also used molecular cytogenetic, microsatellite and ...
Epigenetic memory in mammals
... indicating that most protamines were removed within 30 min following fertilization (van der Heijden et al., 2005). The histones, which associate with the paternal chromatin, are more acetylated than those already present in the maternal chromatin (Lange and Schneider, 2010). It is possible this imba ...
... indicating that most protamines were removed within 30 min following fertilization (van der Heijden et al., 2005). The histones, which associate with the paternal chromatin, are more acetylated than those already present in the maternal chromatin (Lange and Schneider, 2010). It is possible this imba ...
Compulsive disorders in Dobermans WORD
... An SSRI medication, fluoxetine, helps to increase serotonin levels in the brain. SSRIs are most commonly used to help treat depression in people by blocking the reabsorption or reuptake of the neurotransmitter serotonin in the brain. An NMDA receptor antagonist, memantine, a drug used to treat Alzhe ...
... An SSRI medication, fluoxetine, helps to increase serotonin levels in the brain. SSRIs are most commonly used to help treat depression in people by blocking the reabsorption or reuptake of the neurotransmitter serotonin in the brain. An NMDA receptor antagonist, memantine, a drug used to treat Alzhe ...
Gene expression becomes heterogeneous with age
... (A) Age distribution of subjects in the data sets. Human ages are given in years, rat ages in months. In parentheses, the number of subjects is given as ‘N’, the number of probe sets used in quantitative ACHE analyses is given as ‘n’. The ACHE test for increase in heterogeneity with age is conducted ...
... (A) Age distribution of subjects in the data sets. Human ages are given in years, rat ages in months. In parentheses, the number of subjects is given as ‘N’, the number of probe sets used in quantitative ACHE analyses is given as ‘n’. The ACHE test for increase in heterogeneity with age is conducted ...