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mirror of label in #2
mirror of label in #2

... Whey is the preferred protein source in sports and bodybuilding nutrition because it contains superior quality Branched Chain Amino Acids — made up of Leucine, Isoleucine and Valine — which are important for the maintenance of muscle tissue.◊ Unlike some other incomplete protein sources, Body Fortre ...
Proteins - MATERI KULIAH PANGAN
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... Electrophoresis is usually performed on serum rather than plasma since the fibrinogen present in plasma produces a band in the β region that might be mistaken for a paraprotein. M. Zaharna Clin. Chem. 2009 ...
Unit F214/01 - Communication, homeostasis and energy
Unit F214/01 - Communication, homeostasis and energy

... The liver is an organ that is metabolically very active, carrying out over 500 different functions. Some of its important functions include converting chemicals including toxins, into other compounds. Fig. 2.1 outlines some of the reaction pathways that take place in the liver cells. ...
Reversed-Phase High-Performance Liquid Chromatography
Reversed-Phase High-Performance Liquid Chromatography

... group being modified. The sorbents are, therefore, generally subjected to further silanization with a small reactive silane to produce an end-capped packing material. The type of n-alkyl ligand significantly influences the retention of peptides and proteins and can therefore be used to manipulate th ...
Reversed-Phase High-Performance Liquid
Reversed-Phase High-Performance Liquid

... group being modified. The sorbents are, therefore, generally subjected to further silanization with a small reactive silane to produce an end-capped packing material. The type of n-alkyl ligand significantly influences the retention of peptides and proteins and can therefore be used to manipulate th ...
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presentation source

... production and increased glucose utilization (action?) Thiazolidinediones e.g. rosiglitazone or pioglitazone (PPAR- agonist) - what are PPAR’s? ...
Receptors as Drug Targets
Receptors as Drug Targets

... • Agonists bind reversibly to the binding site and produce the same induced fit as the natural messenger - receptor is activated • Similar intermolecular bonds formed as with natural messenger • Agonists are often similar in structure to the natural messenger • The agonist must have the correct bind ...
Electrophoretic Analysis of Native Proteins
Electrophoretic Analysis of Native Proteins

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Constant Growth Rate Can Be Supported by Decreasing Energy
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... exponential growth, suggesting additional physiological roles for aerobic glycolysis. We investigated such roles in yeast batch cultures by quantifying O2 consumption, CO2 production, amino acids, mRNAs, proteins, posttranslational modifications, and stress sensitivity in the course of nine doubling ...
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... (ctrl; A) and Mks1 mutant (m/m; B) animals showed the presence of prominent glomerular and tubule cysts (‘c’) in the mutant animal kidney cortex. Arrows mark glomerular tufts. (C,D)At E18.5, immunostaining with antibody to IFT88 (green) to delineate the cilia (arrows in C,D) showed that cilia were ...
Isoprenoid biosynthesis in bacterial pathogens
Isoprenoid biosynthesis in bacterial pathogens

... make up part of the photosynthetic machinery. As well as structural components isoprenoids also play a role in hormone-based signalling, protein degradation and in the regulation of transcription. All isoprenoids are derived from the universal five-carbon precursor isopentyl diphosphate (IPP) or its ...
AIBSTCT Nucleic Acids Research - Walter Lab
AIBSTCT Nucleic Acids Research - Walter Lab

... Fig2B Immunoprecipitation of SRP19. pSRP19 was transcribed from the SP6 promoter of pGem2 and the transcripts were translated in a wheat germ cell free translation system in the presence of 35S methionine and analysed on 10-15% SDS polyacrylamide gels. SRP19 protein was expressed either as a full-le ...
Phosphate binding sites identification in protein
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... Many important chemical reactions and molecular interactions that occur in the cell involve ligands containing the phosphate group. More than half of known proteins has been shown to interact with a phosphate group (1). Several of these proteins are involved in essential pathways and their malfuncti ...
Chapter 6 Current Views of the Fat Cell as an Endocrine Cell
Chapter 6 Current Views of the Fat Cell as an Endocrine Cell

... cardiac, skeletal muscle, and pancreatic steatosis have been found in ob/ob and db/db mice and fa/fa rats, which have obesity together with increased appetite, hyperlipidemia, and increased blood free FAs (FFAs) [2, 5, 13]. Obese human subjects can have increased intramyocellular lipid in skeletal m ...
Detailed proteome analysis of growing cells of the planctomycete
Detailed proteome analysis of growing cells of the planctomycete

... seven million nucleotides, making it one of the largest marine bacterial genomes sequenced so far with a total of 7325 putative ORFs [4]. The availability of the genome sequence has fuelled the rapid development of functional genomics studies of this bacterium via bioinformatics [5–9] and proteomic ...
Proteins
Proteins

... Electrophoresis is usually performed on serum rather than plasma since the fibrinogen present in plasma produces a band in the β region that might be mistaken for a paraprotein. ...
The GPI Transamidase Complex of Saccharomyces
The GPI Transamidase Complex of Saccharomyces

... studied in microsomal translation/translocation/GPI-anchoring systems (Ramalingam et al., 1996; Sharma et al., 1999) or translocation/GPI-anchoring systems (Doering and Schekman, 1997) in several organisms, and these studies allowed a preliminary biochemical characterization of the GPI transfer reac ...
"Allosteric Activation of Kinases: Design and Application of RapR
"Allosteric Activation of Kinases: Design and Application of RapR

... be tested in vitro. With untagged kinases, immunoprecipitation of endogenous kinases may elevate background levels of kinase activity in the assay. We have chosen to apply the RapR approach to constitutively active kinases. This insures that kinase activity is strictly under the control of the exper ...
In Sweden, Mexico, the United States, and a num
In Sweden, Mexico, the United States, and a num

... that fetal tissue may be useful for treating patients with disabling diseases. For over 50 years, research in animals has demonstrated that fetal tissue has a unique capacity to replace certain cellular deficiencies and so may be useful for treating some chronic diseases of humans. These diseases in ...
Protein and Older Adults
Protein and Older Adults

... cholesterol is a major factor in coronary heart disease; in fact, dietary risk factors for heart disease change with advancing age. Dietary cholesterol and other dietary fats become less of a factor in heart disease risk than in young and middle ages, with cholesterol levels diminishing as people ge ...
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... The high dietary protein requirements of salmonid fish are met with fishmeal-based feed in commercial aquaculture. The sustainability of this practice is questionable and, therefore, the feasibility of substituting fishmeal with plant-based products needs to be investigated. We investigated growth a ...
Purine Biosynthesis. Big in Cell Division, Even
Purine Biosynthesis. Big in Cell Division, Even

... from a range of organisms. In E. coli, each enzyme is monofunctional, except aminoimidazolecarboximide ribonucleotide transformylase/inosine monophosphate cyclohydrolase, which is bifunctional. AIRC has two subunits encoded by the purE and purK genes in E. coli (Zalkin and Dixon, 1992). The organiza ...
Low Catecholamine Concentrations Protect Adult Rat Ventricular
Low Catecholamine Concentrations Protect Adult Rat Ventricular

... for 20 min and protein concentrations in the supernatant were determined by Bio-Rad assay. Equal amounts of protein were gently rotated at 4°C with anti-ERK2 immunoglobulin (Santa Cruz Biotechnology, Le Perray-en-Yvelines, France) for 1 h and then with protein A-agarose (Santa Cruz Biotechnology) fo ...
The Lamin B Receptor of the Nuclear Envelope Inner Membrane: A
The Lamin B Receptor of the Nuclear Envelope Inner Membrane: A

... integral membrane proteins that may be involved in the anchorage of these structures. In support of this notion, several integral membrane proteins associated with these structures have been identified and localized to specific nuclear envelope membrane domains. An integral membrane glycoprotein (gp ...
Control of cell differentiation and morphogenesis in amphibian
Control of cell differentiation and morphogenesis in amphibian

... in unfertilized eggs and blastulae of Xenopus has been demonstrated (Asashima el al., 1991b) even before the 16-cell stage of early embryos (Fukui et al.. 1994). Activin homologs are, indeed, contained in an egg of Xenopus laevis in a considerable amount (about 1 pg/egg) as a maternal protein. These ...
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Paracrine signalling



Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.
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