Cell Organelles
... endoplasmic reticulum consist of a system of membranous tubules and pouches called cisternae, which is held together by the cytoskeleton. The membrane segregates the inside section of the endoplasmic reticulum from the outside section (cytosol) . The internal section is called the lumen cavity, but ...
... endoplasmic reticulum consist of a system of membranous tubules and pouches called cisternae, which is held together by the cytoskeleton. The membrane segregates the inside section of the endoplasmic reticulum from the outside section (cytosol) . The internal section is called the lumen cavity, but ...
Patterning the Xenopus blastula - Development
... bind to EGF receptor (Hoschuetzky et al., 1994), c-erbB-2 (Kanai et al., 1995), fascin (Tao et al., 1996) and the cytoplasmic protein adenomatous polyposis coli (APC) protein. APC is expressed in early Xenopus embryos (Vleminckx et al., 1997), where it may be involved in regulating the levels of βca ...
... bind to EGF receptor (Hoschuetzky et al., 1994), c-erbB-2 (Kanai et al., 1995), fascin (Tao et al., 1996) and the cytoplasmic protein adenomatous polyposis coli (APC) protein. APC is expressed in early Xenopus embryos (Vleminckx et al., 1997), where it may be involved in regulating the levels of βca ...
Identification of Major Proteins in Maize Egg Cells
... triosephosphate isomerase, which also belongs to the enzymes of the glycolytic pathway. Calculated molecular mass and isoelectric point of cytosolic triosephosphate isomerase (accession number GI136063) are 27,292 and 5.52, respectively. These values fit the position of the gel where spot 5 was dete ...
... triosephosphate isomerase, which also belongs to the enzymes of the glycolytic pathway. Calculated molecular mass and isoelectric point of cytosolic triosephosphate isomerase (accession number GI136063) are 27,292 and 5.52, respectively. These values fit the position of the gel where spot 5 was dete ...
Defining How Botulinum Toxin Binds to the
... Recently, the Stevens Laboratory at The Scripps Research Institute, in collaboration with the Marks laboratory at UCSF and the Chapman and Johnson laboratories at the University of Wisconsin, Madison, completed structural studies on the structures of botulinum toxin in complex with the neuronal cell ...
... Recently, the Stevens Laboratory at The Scripps Research Institute, in collaboration with the Marks laboratory at UCSF and the Chapman and Johnson laboratories at the University of Wisconsin, Madison, completed structural studies on the structures of botulinum toxin in complex with the neuronal cell ...
Biuret test - WordPress.com
... charged. Neutralization of this charge bring proteins to the isoelectric point. At this point, maximum precipitation of proteins take place and the protein particles bear zero net charge. Each protein has its own isoelectric point, since they may be precipitating by providing the positively charged ...
... charged. Neutralization of this charge bring proteins to the isoelectric point. At this point, maximum precipitation of proteins take place and the protein particles bear zero net charge. Each protein has its own isoelectric point, since they may be precipitating by providing the positively charged ...
The Role of Two-Component Signal Transduction Systems in
... signaling (Fig. 3A). This includes so-called GGDEF domains, which are typically diguanylate cyclases that synthesize c-di-GMP, and EAL and HD-GYP domains, which function as phosphodiesterases for c-di-GMP (Jenal and Malone, 2006). In most bacteria, the production of c-di-GMl> plays a critical role i ...
... signaling (Fig. 3A). This includes so-called GGDEF domains, which are typically diguanylate cyclases that synthesize c-di-GMP, and EAL and HD-GYP domains, which function as phosphodiesterases for c-di-GMP (Jenal and Malone, 2006). In most bacteria, the production of c-di-GMl> plays a critical role i ...
Lipoproteins
... Mutations affecting the LDL receptor are associated with the most common form of the disease familial hypercholesterolemia (high blood cholesterol). Cells lacking functional LDL receptors cannot take up LDL. As a result, the amount of circulating LDL increases, leading to enhanced risk of developin ...
... Mutations affecting the LDL receptor are associated with the most common form of the disease familial hypercholesterolemia (high blood cholesterol). Cells lacking functional LDL receptors cannot take up LDL. As a result, the amount of circulating LDL increases, leading to enhanced risk of developin ...
MSc in Biochemistry Dissertation Project – 2nd Cycle Student´s
... proteins and lipids, with an unsurpassed capacity to generate a wide array of structures (Annu. Rev. Biomed. Eng. 2007, 9, 121–167). The large polypeptide GalNAc-transferase (GalNAc-Ts) family catalyzes the transfer of N-acetylgalactosamine (GalNAc) from a sugar donor UDP-GalNAc to Ser/Thr side chai ...
... proteins and lipids, with an unsurpassed capacity to generate a wide array of structures (Annu. Rev. Biomed. Eng. 2007, 9, 121–167). The large polypeptide GalNAc-transferase (GalNAc-Ts) family catalyzes the transfer of N-acetylgalactosamine (GalNAc) from a sugar donor UDP-GalNAc to Ser/Thr side chai ...
Chapter-1-Structure-and-Variety-of-Protein
... More jobs of proteins. • FIBRINOGEN and PROTHROMBIN are proteins which protect the body by clotting the blood at wounds. • All membranes are made of proteins, • The cell has a CYTOSKELETON which is made of protein. E.g. Microvillus, spindle fibres, and cilia all keep their shape because of their pro ...
... More jobs of proteins. • FIBRINOGEN and PROTHROMBIN are proteins which protect the body by clotting the blood at wounds. • All membranes are made of proteins, • The cell has a CYTOSKELETON which is made of protein. E.g. Microvillus, spindle fibres, and cilia all keep their shape because of their pro ...
Although ABA is mainly made in the leaves and the root cap, all
... ABA-induced Ca2+ increase is mediated by second messengers, IP3 and cADPR. cADPR has been shown to induce cytosolic Ca2+ increase and stomatal closure in Commelina guard cells (Leckie et al., 1998). Also in tomato hypocotyls cells, microinjected cADPR induced ABA-inducible gene expression that can ...
... ABA-induced Ca2+ increase is mediated by second messengers, IP3 and cADPR. cADPR has been shown to induce cytosolic Ca2+ increase and stomatal closure in Commelina guard cells (Leckie et al., 1998). Also in tomato hypocotyls cells, microinjected cADPR induced ABA-inducible gene expression that can ...
Sequence and Structural Similarities Between Glyceraldehyde
... DING proteins, named for the presence of the amino acids, in their single letter abbreviation, DINGGGN, and located in the carboxyl termini of these proteins resemble periplasmic binding proteins. DING proteins are ubiquitous in living organisms(8). Many DING proteins have been isolated in eukaryo ...
... DING proteins, named for the presence of the amino acids, in their single letter abbreviation, DINGGGN, and located in the carboxyl termini of these proteins resemble periplasmic binding proteins. DING proteins are ubiquitous in living organisms(8). Many DING proteins have been isolated in eukaryo ...
Supporting Online Material for
... For co-immunoprecipitation studies, antibodies against the FLAG, V5 or c-myc epitopes were used to precipitate proteins in the presence of 20μl protein A/G beads (Santa Cruz) overnight at 4ºC. Protein complexes were washed four times in either lysis or RIPA buffer, incubated at 95ºC for 5 minutes a ...
... For co-immunoprecipitation studies, antibodies against the FLAG, V5 or c-myc epitopes were used to precipitate proteins in the presence of 20μl protein A/G beads (Santa Cruz) overnight at 4ºC. Protein complexes were washed four times in either lysis or RIPA buffer, incubated at 95ºC for 5 minutes a ...
Glycine-rich proteins as structural components of plant cell walls
... homologous to grp1.8 or ptgrp1 are predominantly expressed in vascular tissue. In some cases grp expression has been shown to be developmentally regulated. ptgrp1 as well as the grp1.8 and grp1.8-like gene(s) are mainly expressed in young tissue, whereas the expression in older stages of development ...
... homologous to grp1.8 or ptgrp1 are predominantly expressed in vascular tissue. In some cases grp expression has been shown to be developmentally regulated. ptgrp1 as well as the grp1.8 and grp1.8-like gene(s) are mainly expressed in young tissue, whereas the expression in older stages of development ...
Lecture 5: Major Nutrient Groups
... secondary: forces generated by the close proximity of one AA residue to another (e.g., helix design or pleated sheet)(i.e., certain amino acids can form bonds with others, if close enough, cysteine) tertiary: bending of one AA chain due to attraction of individual AA’s distant from each other qu ...
... secondary: forces generated by the close proximity of one AA residue to another (e.g., helix design or pleated sheet)(i.e., certain amino acids can form bonds with others, if close enough, cysteine) tertiary: bending of one AA chain due to attraction of individual AA’s distant from each other qu ...
Protein For Athletes
... Athletes who find it tough to meet their daily protein requirements because of poor or restricted diets may use protein shakes, bars or other high-protein snacks to supplement their daily protein needs. Is More Protein Better? Protein — or more accurately, amino acids — is pulled into the muscles; ...
... Athletes who find it tough to meet their daily protein requirements because of poor or restricted diets may use protein shakes, bars or other high-protein snacks to supplement their daily protein needs. Is More Protein Better? Protein — or more accurately, amino acids — is pulled into the muscles; ...
Intrinsically Disordered Domains of the B Cell Receptor
... Integral membrane proteins (MPs), embedded in the membrane, provide critical roles in cell-to-cell contact, cytoskeleton contact, surface recognition, signaling, enzymatic activity and transportation of substances across the membrane [1]. MPs are also important for drug research, accounting for over ...
... Integral membrane proteins (MPs), embedded in the membrane, provide critical roles in cell-to-cell contact, cytoskeleton contact, surface recognition, signaling, enzymatic activity and transportation of substances across the membrane [1]. MPs are also important for drug research, accounting for over ...
DOPAMINE RECEPTORS
... different G-proteins and effectors are involved in their signalling pathways (Table 1). Although biochemical studies gave some indications of further heterogeneity of these dopamine receptor subtypes, it was not until the late 1980’s that the true extent of this was revealed by the application of ge ...
... different G-proteins and effectors are involved in their signalling pathways (Table 1). Although biochemical studies gave some indications of further heterogeneity of these dopamine receptor subtypes, it was not until the late 1980’s that the true extent of this was revealed by the application of ge ...
Protein-protein interactions.
... the distance between two residues. • If distance between two nonadjacent residues in the template is less than 8 Å, these residues make a contact. ...
... the distance between two residues. • If distance between two nonadjacent residues in the template is less than 8 Å, these residues make a contact. ...
Differential Internalization of the Prostaglandin F2α Receptor
... mRNA splicing that gives rise to differences in their intracellular carboxyl-terminal domain. Studies on these receptor isoforms have demonstrated that upon stimulation with PGF2␣ more than one signaling pathway can be activated. Thus, stimulation of either FP receptor isoform by PGF2␣ has been show ...
... mRNA splicing that gives rise to differences in their intracellular carboxyl-terminal domain. Studies on these receptor isoforms have demonstrated that upon stimulation with PGF2␣ more than one signaling pathway can be activated. Thus, stimulation of either FP receptor isoform by PGF2␣ has been show ...
Enzymes: Regulation 1
... 5 principal ways protein/enzyme activity is regulated 1. Allosteric control • Regulate binding affinity for ligands, and/or of catalytic activity, by conformational changes caused by binding of the same or other ligands at other sites on protein ("allosteric effects") • Changes involve simple associ ...
... 5 principal ways protein/enzyme activity is regulated 1. Allosteric control • Regulate binding affinity for ligands, and/or of catalytic activity, by conformational changes caused by binding of the same or other ligands at other sites on protein ("allosteric effects") • Changes involve simple associ ...
the cortex adhaerens mosaic of lens fiber cells
... known only from certain other cell types, must be added to the list of major lens cortex proteins. We here discuss its possible functional importance for the maintenance of lens structure and functions, notably clear and sharp vision. Key words: Lens fibers, Adherens Junctions, Cortex adhaerens, Cad ...
... known only from certain other cell types, must be added to the list of major lens cortex proteins. We here discuss its possible functional importance for the maintenance of lens structure and functions, notably clear and sharp vision. Key words: Lens fibers, Adherens Junctions, Cortex adhaerens, Cad ...
NutriStem hESC XF Serum
... The TGF-β family is part of a super-family of peptide structural proteins all encoded as large protein precursors found in both adult organisms and the developing embryo. Some of the major functions of this protein include, among many others: § Angiogenesis § Apoptosis § Cellular Differentiation § C ...
... The TGF-β family is part of a super-family of peptide structural proteins all encoded as large protein precursors found in both adult organisms and the developing embryo. Some of the major functions of this protein include, among many others: § Angiogenesis § Apoptosis § Cellular Differentiation § C ...
- de Duve Institute
... The aim of our research is to understand the molecular mechanisms underlying a variety of disorders of the cardiovascular and skeletal systems, as well as certain cancers. We are especially interested in evaluating the contribution of genetic variation to human disease. The bases of many disorders r ...
... The aim of our research is to understand the molecular mechanisms underlying a variety of disorders of the cardiovascular and skeletal systems, as well as certain cancers. We are especially interested in evaluating the contribution of genetic variation to human disease. The bases of many disorders r ...
Gene Section PTPRJ (protein tyrosine phosphatase, receptor type, J)
... DEP-1 is a candidate human homologue of the mouse colon cancer susceptibility locus SCC1. Germline allele-specific epigenetic silencing of the gene PTPRJ, encoding DEP-1, is described in earlyonset familial colorectal cancer, due to a 170-kb intragenic duplication affecting the 5' end of the phospha ...
... DEP-1 is a candidate human homologue of the mouse colon cancer susceptibility locus SCC1. Germline allele-specific epigenetic silencing of the gene PTPRJ, encoding DEP-1, is described in earlyonset familial colorectal cancer, due to a 170-kb intragenic duplication affecting the 5' end of the phospha ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.