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A1989CB63700001
A1989CB63700001

... variability under the bottleneck effect depends not only on the bottleneck size but also on the rate of population growth; (2) once heterozygosity is reduced, it takes hundreds of thousands of years for it to recover to the original level; (3) the number of alleles per locus is reduced more drastica ...
B Ca(2+)
B Ca(2+)

... line used was yw;sytAD4/sytAD4 P[elavGal4]. To maximize neuronal expression of syt transgenes in the sytnull mutant line, we used the Gal4/UAS amplification system in combination with the pan neuronal elav promoter1-3. The genotype of the transgenic lines used were: P[sytwt] = yw; sytAD4/sytAD4 P[el ...
ppt - University of Illinois Urbana
ppt - University of Illinois Urbana

... structure patterns of the family members to reveal shared characteristics that potentially describe common biological properties – Multiple sequence alignment – Motif/Domain - sequence and/or structure patterns common to protein family members (a trait) – Profile is a way to represent a family of pr ...
BrevdueNord.dk PRACTICAL FEEDING FOR PERFORMANCE By
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... energy released. The energy in fat can be released by metabolic pathways that do not require oxygen, but the amount of energy released, is not as much as that released from carbohydrates. Finally, if the pigeon is still not home, muscle tissue (and other proteins in the body) start to breakdown. Aft ...
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... Objective 3: The test tube assays confirmed that Spirulina is a viable protein source for use in this study to determine the effects of filter feeding on microbial diversity. The next step was to isolate bacteria that could metabolize the protein. A minimal culture medium was developed with the Spir ...
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... Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. ...
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... detection of His-tagged proteins, protein size was confirmed on the blot using a ladder. In contrast, control sample with without DNA had no His-tagged signal. Additionally, there were not significant differences between different concentrations in pSG73 and pSG75, suggesting masstra ...
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sv-lncs - Department of Computer Science and Engineering
sv-lncs - Department of Computer Science and Engineering

... data, these domain pairs predict protein interactions. The probability of each observed protein pair is calculated. If the probability is greater than some threshold this protein pair is predicted to be interacting. The number of matches between the predicted data set and observed data set is increa ...
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... _____ Changing the primary structure of Protein G is likely to change Protein G function. _____ Changing the secondary structure of Protein G is likely to change protein Protein G function. _____ Changing the tertiary structure of Protein G is likely to change protein Protein G function. _____ Chang ...
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Potassium sulfate - Sigma
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... and confirmed in Parkinson's disease where amplification has already been reported21. Second, prevention of amplification is a disease-controlling strategy; complete knock-down of substrate protein is unnecessary. Third, intracrinelike networks linking the regulation of various misfolded proteins sh ...
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Potassium sulfate ACS Reagent Product Number - Sigma

... unfolding of tropomyosin has been investigated. Potassium sulfate has been used in studies on electrostatic effects on pKa values of amino acid ...
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... exists as subtypes with very different clinical courses. CLL is generally described as a disease of failed apoptosis. Apoptosis resistance may stem from a combination of microenvironmental survival signals as well as from intrinsic alterations in the apoptotic machinery within the CLL cell. The mole ...
Assembly and function of cell surface structures of the
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... The bindosome assembly (bas) system is composed of 5 genes, i.e., basEFABC (Zolghadr et al., 2007). The basE gene encodes a cytosolic ATPase while the basF gene specifies a membrane protein. The purification of tagged BasF lead to the co-isolation of BasE demonstrating that these are interacting pro ...
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... minutes. Proteins were isolated from cell extract using acetone precipitation and then purified to homogeneity on a Sephadex G100 column (2cm x 50cm), equilibrated with 0.05M sodium phosphate buffer at pH 7.0, the protein was eluted in 0.1 M sodium chloride. The eluted protein was collected in 8 suc ...
檔案下載 - 國立宜蘭大學生物技術與動物科學系
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... – The structure and function of a protein depends on protein folding – If protein is folded incorrectly, desired function of a protein is lost and a misfolded protein can be detrimental – 1951 two regular structures were described • Alpha helices and beta sheets • Structures are fragile; hydrogen bo ...
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... Schematic illustration of chimeric MLL-SMAP1 protein. The authentic MLL and SMAP1 proteins are also shown. AT hook, an AT-hook domain; NLS, a nuclear localization signal; MT, a methyltransferase domain; PHD, a plant homeodomain zinc finger; BROMO, a bromo domain; SET, a su(var)3-9, enhancer-of-zeste ...
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Molecular Dynamics Simulations of Protein

... Integrins recognise specific amino acid sequences on extracellular matrix proteins and so surfaces must be designed to adsorb proteins in the correct orientation for integrin binding Control over adhesion achieved by manipulation of surface properties – isoelectric point, functional group terminatio ...
Gene Section CPEB4 (cytoplasmic polyadenylation element binding protein 4)
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... CPEBs are RNA binding proteins that recognize cis-acting elements named Cytoplasmic Polyadenylation Element (CPE), that are located in the 3'UTR of some mRNAs. They were originally described in Xenopus laevis oocytes, where they control translation of maternal mRNAs during meiosis by regulation of t ...
File S1. Retained and eliminated proteins (represented by ESTs and
File S1. Retained and eliminated proteins (represented by ESTs and

... associated proteins and are unlikely to be secreted into saliva. Rps19 Ribosomal protein S19 (chr7:25669390-25674825; Accession number IPI00113241) Ribosomal proteins are part of the cellular machinery involved in translation of mRNAs into protein and are not secreted in exocrine fluids such as sali ...
Chapter 8 - TeacherWeb
Chapter 8 - TeacherWeb

... The bonds in water, carbon dioxide, and sugar are very different but they do have some similarities Low melting and boiling points  Usually gases or liquids at room temperature  Poor conductors of thermal energy and electricity ...
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Cyclol



The cyclol hypothesis is the first structural model of a folded, globular protein. It was developed by Dorothy Wrinch in the late 1930s, and was based on three assumptions. Firstly, the hypothesis assumes that two peptide groups can be crosslinked by a cyclol reaction (Figure 1); these crosslinks are covalent analogs of non-covalent hydrogen bonds between peptide groups. These reactions have been observed in the ergopeptides and other compounds. Secondly, it assumes that, under some conditions, amino acids will naturally make the maximum possible number of cyclol crosslinks, resulting in cyclol molecules (Figure 2) and cyclol fabrics (Figure 3). These cyclol molecules and fabrics have never been observed. Finally, the hypothesis assumes that globular proteins have a tertiary structure corresponding to Platonic solids and semiregular polyhedra formed of cyclol fabrics with no free edges. Such ""closed cyclol"" molecules have not been observed either.Although later data demonstrated that this original model for the structure of globular proteins needed to be amended, several elements of the cyclol model were verified, such as the cyclol reaction itself and the hypothesis that hydrophobic interactions are chiefly responsible for protein folding. The cyclol hypothesis stimulated many scientists to research questions in protein structure and chemistry, and was a precursor of the more accurate models hypothesized for the DNA double helix and protein secondary structure. The proposal and testing of the cyclol model also provides an excellent illustration of empirical falsifiability acting as part of the scientific method.
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