![Problem Set 1](http://s1.studyres.com/store/data/015904460_1-779354f020a81ec69812c1e00f540570-300x300.png)
Problem Set 1
... ii) The carbonyl and amide groups of the protein backbone are hydrophilic and form hydrogen bonds with water; they can also hydrogen bond to each other. The free energy of formation of a hydrogen bond between the atoms of the peptide group in the interior of a protein is : a) more favorable than it ...
... ii) The carbonyl and amide groups of the protein backbone are hydrophilic and form hydrogen bonds with water; they can also hydrogen bond to each other. The free energy of formation of a hydrogen bond between the atoms of the peptide group in the interior of a protein is : a) more favorable than it ...
The Chemistry of Molecular Biology
... attaches to nitrogen of purine or pyrimidine • Acidic nature due to phosphate group • Nucleotides are linked by phosphodiester bonds ...
... attaches to nitrogen of purine or pyrimidine • Acidic nature due to phosphate group • Nucleotides are linked by phosphodiester bonds ...
Modelling Proteomes
... expanded irregular unique shape precisely ordered stable/functional globular/compact helices and sheets ...
... expanded irregular unique shape precisely ordered stable/functional globular/compact helices and sheets ...
Biological Molecules
... Polymerization—chemical reactions that link two or more small molecules to form larger molecules with repeating structural units Condensation Reaction—polymerization reaction which form covalent links producing net removal of a water molecule for each covalent bond formed Hydrolysis—reaction that br ...
... Polymerization—chemical reactions that link two or more small molecules to form larger molecules with repeating structural units Condensation Reaction—polymerization reaction which form covalent links producing net removal of a water molecule for each covalent bond formed Hydrolysis—reaction that br ...
Organic Compounds
... Proteins they are used to make plastics and synthetic fibers. _________________________ provide organisms with quick energy. _________________________ are made of hydrogen and carbon but not other elements. ______________________are best for stored energy and not soluble in water. ...
... Proteins they are used to make plastics and synthetic fibers. _________________________ provide organisms with quick energy. _________________________ are made of hydrogen and carbon but not other elements. ______________________are best for stored energy and not soluble in water. ...
Antibody
... • A collective name for the proteins expressed by the genome • Dynamic and functional information • It varies with cell type, developmental stage, and environmental condition such as the presence of hormones. • Regulation of mRNA synthesis, alternative splicing, mRNA stability, rate of protein synth ...
... • A collective name for the proteins expressed by the genome • Dynamic and functional information • It varies with cell type, developmental stage, and environmental condition such as the presence of hormones. • Regulation of mRNA synthesis, alternative splicing, mRNA stability, rate of protein synth ...
Aromatic Amino Acids
... Aliphatic R groups are nonpolar and hydrophobic. Hydrophobicity increases with increasing number of C atoms in the hydrocarbon chain. Although these amino acids prefer to remain inside protein molecules, alanine and glycine are ambivalent, meaning that they can be inside or outside the protein molec ...
... Aliphatic R groups are nonpolar and hydrophobic. Hydrophobicity increases with increasing number of C atoms in the hydrocarbon chain. Although these amino acids prefer to remain inside protein molecules, alanine and glycine are ambivalent, meaning that they can be inside or outside the protein molec ...
Libraries of Specific Assays Covering Whole
... 2-stage mass-selection system first selects the known mass of the peptide (calculated exactly from the amino acid sequence), then fragments the peptide (generally through collision with gas atoms), and finally selects 1 specific fragment of known sequence, which is counted at a detector. The pair of ...
... 2-stage mass-selection system first selects the known mass of the peptide (calculated exactly from the amino acid sequence), then fragments the peptide (generally through collision with gas atoms), and finally selects 1 specific fragment of known sequence, which is counted at a detector. The pair of ...
Population Genetics
... a polypeptide • A protein has an amino (the first amino acid in the chain) and a carboxyl (the last amino acid in a chain) ends ...
... a polypeptide • A protein has an amino (the first amino acid in the chain) and a carboxyl (the last amino acid in a chain) ends ...
Tae-Eun Kim
... individual amino acids, zoom way out to see the protein as a whole, and assign colors to certain molecules, bonds, subunits...etc. It made more sense for me to understand, for example the properties of beta sheets, by seeing it rather than reading a paragraph about it in a book. ...
... individual amino acids, zoom way out to see the protein as a whole, and assign colors to certain molecules, bonds, subunits...etc. It made more sense for me to understand, for example the properties of beta sheets, by seeing it rather than reading a paragraph about it in a book. ...
Structure of Organic Compounds - Cornell Notes
... The three types of lipids are ______________, _____________, and _______________. ...
... The three types of lipids are ______________, _____________, and _______________. ...
Biology 231
... R group – unique group for each different amino acid peptide bond – dehydration synthesis links amino acids peptide – chain of amino acids (2) dipeptide, (3) tripeptide, (>3) polypeptide proteins – large polypeptides; may be very structurally complex function is related to shape primary structure – ...
... R group – unique group for each different amino acid peptide bond – dehydration synthesis links amino acids peptide – chain of amino acids (2) dipeptide, (3) tripeptide, (>3) polypeptide proteins – large polypeptides; may be very structurally complex function is related to shape primary structure – ...
The Fluid Mosaic Model
... membrane proteins vary greatly between different cells. It was unclear how the proteins in the model would permit the membrane to change shape without bonds being broken. Membrane proteins are largely hydrophobic and therefore should not be found where the model positioned them: in the aqueous c ...
... membrane proteins vary greatly between different cells. It was unclear how the proteins in the model would permit the membrane to change shape without bonds being broken. Membrane proteins are largely hydrophobic and therefore should not be found where the model positioned them: in the aqueous c ...
The Fluid Mosaic Model - Chatsworth High School
... membrane proteins vary greatly between different cells. It was unclear how the proteins in the model would permit the membrane to change shape without bonds being broken. Membrane proteins are largely hydrophobic and therefore should not be found where the model positioned them: in the aqueous c ...
... membrane proteins vary greatly between different cells. It was unclear how the proteins in the model would permit the membrane to change shape without bonds being broken. Membrane proteins are largely hydrophobic and therefore should not be found where the model positioned them: in the aqueous c ...
Comparative Biochemistry
... To identify and give the functional properties of oxygen – binding pigments in vertebrates and invertebrates. To compare the intermediary metabolism of vertebrates with that of terrestrial and marine-based invertebrates. To identify the kinetic components of the control mechanisms in obligate and fa ...
... To identify and give the functional properties of oxygen – binding pigments in vertebrates and invertebrates. To compare the intermediary metabolism of vertebrates with that of terrestrial and marine-based invertebrates. To identify the kinetic components of the control mechanisms in obligate and fa ...
structbio_lecture_BCH339N_2016
... Profiles can be built from multiple sequence alignments and contain frequencies of all amino acids in each column. This has more information than a single ...
... Profiles can be built from multiple sequence alignments and contain frequencies of all amino acids in each column. This has more information than a single ...
Week 5 Assignment 1. Reverse Phase Arrays (RPA) involve printing
... Yes, is it necessary. These is a high probability of sequence could be modified during recombination process. No, it is not necessary. There is a high probability that the sequence would continue to remain unchanged. ...
... Yes, is it necessary. These is a high probability of sequence could be modified during recombination process. No, it is not necessary. There is a high probability that the sequence would continue to remain unchanged. ...
Electrophoresis
... porosity is chosen based on the specific weight and porosity of the target molecules. ...
... porosity is chosen based on the specific weight and porosity of the target molecules. ...
Isoelectric focusing
... porosity is chosen based on the specific weight and porosity of the target molecules. ...
... porosity is chosen based on the specific weight and porosity of the target molecules. ...
Posttranslational Modification
... is characterized by an N-acetylgalactosamine (GalNAc) residue -linked to the hydroxyl group of Ser or Thr. GalNAc residue is installed by a family of 24 N-acetylgalactosaminyltransferases, then further elaborated by a series of glycosyltransferases to generate higher-order O-linked structures. ...
... is characterized by an N-acetylgalactosamine (GalNAc) residue -linked to the hydroxyl group of Ser or Thr. GalNAc residue is installed by a family of 24 N-acetylgalactosaminyltransferases, then further elaborated by a series of glycosyltransferases to generate higher-order O-linked structures. ...
The Components of Life
... organisms are called organic compounds • In order for a compound to be considered organic it must have a Carbon Atom (C) and a Hydrogen Atom (H) ...
... organisms are called organic compounds • In order for a compound to be considered organic it must have a Carbon Atom (C) and a Hydrogen Atom (H) ...
NUTRITION & DIGESTION - Fox Valley Lutheran High School
... roughage, which stimulates digestion. Lettuce, celery, whole grain ...
... roughage, which stimulates digestion. Lettuce, celery, whole grain ...
Cyclol
![](https://commons.wikimedia.org/wiki/Special:FilePath/Cyclol_reaction.png?width=300)
The cyclol hypothesis is the first structural model of a folded, globular protein. It was developed by Dorothy Wrinch in the late 1930s, and was based on three assumptions. Firstly, the hypothesis assumes that two peptide groups can be crosslinked by a cyclol reaction (Figure 1); these crosslinks are covalent analogs of non-covalent hydrogen bonds between peptide groups. These reactions have been observed in the ergopeptides and other compounds. Secondly, it assumes that, under some conditions, amino acids will naturally make the maximum possible number of cyclol crosslinks, resulting in cyclol molecules (Figure 2) and cyclol fabrics (Figure 3). These cyclol molecules and fabrics have never been observed. Finally, the hypothesis assumes that globular proteins have a tertiary structure corresponding to Platonic solids and semiregular polyhedra formed of cyclol fabrics with no free edges. Such ""closed cyclol"" molecules have not been observed either.Although later data demonstrated that this original model for the structure of globular proteins needed to be amended, several elements of the cyclol model were verified, such as the cyclol reaction itself and the hypothesis that hydrophobic interactions are chiefly responsible for protein folding. The cyclol hypothesis stimulated many scientists to research questions in protein structure and chemistry, and was a precursor of the more accurate models hypothesized for the DNA double helix and protein secondary structure. The proposal and testing of the cyclol model also provides an excellent illustration of empirical falsifiability acting as part of the scientific method.