Glycolysis
... ∆Go’ = -85 kJ/mol 9 of the ten metabolites of glycolysis are phosphorylated. Phosphorylated intermediates serve 3 ...
... ∆Go’ = -85 kJ/mol 9 of the ten metabolites of glycolysis are phosphorylated. Phosphorylated intermediates serve 3 ...
Defelipe, L.A, Dolghih E, Roitberg A.E., Nouzova M., Mayoral
... Fig. 3A and B show the lowest energy conformers for (10R)-JHA and FA, respectively, where the carboxyl group of the substrates are oriented toward the methyl group of SAM, allowing the catalytic transfer. The substrate carboxyl groups of (10R)-JHA and FA fit nicely to form hydrogen bonds with the Trp ...
... Fig. 3A and B show the lowest energy conformers for (10R)-JHA and FA, respectively, where the carboxyl group of the substrates are oriented toward the methyl group of SAM, allowing the catalytic transfer. The substrate carboxyl groups of (10R)-JHA and FA fit nicely to form hydrogen bonds with the Trp ...
Gene Section GHRL (ghrelin/obestatin prepropeptide) Atlas of Genetics and Cytogenetics
... secretagogues (GHS) receptor, Ghrelin/MTLRP is involved in the pulsatile secretion of Growth hormone. In addition to this role Ghrelin/MTLRP is in the regulation of feeding. In rodent In contrast to leptin, Ghrelin/MTLRP promotes food intake and obesity. In addition Ghrelin/MTLRP stimulates motricit ...
... secretagogues (GHS) receptor, Ghrelin/MTLRP is involved in the pulsatile secretion of Growth hormone. In addition to this role Ghrelin/MTLRP is in the regulation of feeding. In rodent In contrast to leptin, Ghrelin/MTLRP promotes food intake and obesity. In addition Ghrelin/MTLRP stimulates motricit ...
A novel zinc-dependent D-serine dehydratase
... of normal L-aminoacyl tRNAs and cause a delay of cell growth [12]. In S. cerevisiae cells, D-tyrosine was found to serve as a substrate of tyrosine tRNA synthase [13]. It is possible that the formation of D-aminoacyl tRNAs is one of the reasons for the toxicity of D-amino acids to S. cerevisiae cell ...
... of normal L-aminoacyl tRNAs and cause a delay of cell growth [12]. In S. cerevisiae cells, D-tyrosine was found to serve as a substrate of tyrosine tRNA synthase [13]. It is possible that the formation of D-aminoacyl tRNAs is one of the reasons for the toxicity of D-amino acids to S. cerevisiae cell ...
Terpene Biosynthesis
... general base to deprotonate the C-2 methyl group of acetyl-Senzyme and a general acid that protonates the C-3 carbonyl of acetoacetyl-CoA cannot be tenable. The observations point to a more detailed mechanism and possible roles for acid/base catalysts as shown in Scheme 2. By replacing Glu-95 with A ...
... general base to deprotonate the C-2 methyl group of acetyl-Senzyme and a general acid that protonates the C-3 carbonyl of acetoacetyl-CoA cannot be tenable. The observations point to a more detailed mechanism and possible roles for acid/base catalysts as shown in Scheme 2. By replacing Glu-95 with A ...
Engineering of Metabolic Pathways and Global Regulators of
... Eicosapentaenoic Acid Yarrowia native pathway ...
... Eicosapentaenoic Acid Yarrowia native pathway ...
Calvin Cycle
... Plants designated C4 have one cell type in which phosphoenolpyruvate (PEP) is carboxylated via the enzyme PEP Carboxylase, to yield the 4-C oxaloacetate. Oxaloacetate is converted to other 4-C intermediates that are transported to cells active in photosynthesis, where CO2 is released by decarboxyl ...
... Plants designated C4 have one cell type in which phosphoenolpyruvate (PEP) is carboxylated via the enzyme PEP Carboxylase, to yield the 4-C oxaloacetate. Oxaloacetate is converted to other 4-C intermediates that are transported to cells active in photosynthesis, where CO2 is released by decarboxyl ...
Plant and Soil 287:
... genes, thus allowing GA production. Another type of gene (gabY) involved in GA production and MPS was cloned from Pseudomonas cepacia (Babu-Khan et al., 1995). The deduced amino acid sequence showed no homology with previously cloned direct oxidation pathway (GA synthesis) genes, but was similar to ...
... genes, thus allowing GA production. Another type of gene (gabY) involved in GA production and MPS was cloned from Pseudomonas cepacia (Babu-Khan et al., 1995). The deduced amino acid sequence showed no homology with previously cloned direct oxidation pathway (GA synthesis) genes, but was similar to ...
09_Lecture
... • Only substances whose concentrations change appear in an equilibrium expression. • Solids (s) and pure liquids (l) have constant concentrations so do not appear in the equilibrium expression. • If K is equal to 1, the ratio of products:reactants is 1:1 or [products] = [reactants]. • A value of K g ...
... • Only substances whose concentrations change appear in an equilibrium expression. • Solids (s) and pure liquids (l) have constant concentrations so do not appear in the equilibrium expression. • If K is equal to 1, the ratio of products:reactants is 1:1 or [products] = [reactants]. • A value of K g ...
PostScript - Theoretical Biochemistry Group
... single, uncompensated, point mutations can give rise to large conformational changes. Compensatory mutations are indeed frequently observed in phylogenetic data (Dixon and Hillis 1993). It is therefore worth investigating whether a mutation not affecting the function of the encoded protein would als ...
... single, uncompensated, point mutations can give rise to large conformational changes. Compensatory mutations are indeed frequently observed in phylogenetic data (Dixon and Hillis 1993). It is therefore worth investigating whether a mutation not affecting the function of the encoded protein would als ...
File
... acid has a certain chemical character in relation to water molecules. Some amino acids love being around water (Hydrophilic), some hate water and hide from it (Hydrophobic), and for some, it doesn’t matter as much. Proteins do not exist as a string of amino acids, but must fold into a 3 dimensional ...
... acid has a certain chemical character in relation to water molecules. Some amino acids love being around water (Hydrophilic), some hate water and hide from it (Hydrophobic), and for some, it doesn’t matter as much. Proteins do not exist as a string of amino acids, but must fold into a 3 dimensional ...
print
... • Nitriles also have dipole-dipole interactions, because they have a polar C≡N group. • Because they contain one or two N–H bonds, 1° and 2° amides are capable of intermolecular hydrogen bonding and will have substantially higher melting and boiling points. ...
... • Nitriles also have dipole-dipole interactions, because they have a polar C≡N group. • Because they contain one or two N–H bonds, 1° and 2° amides are capable of intermolecular hydrogen bonding and will have substantially higher melting and boiling points. ...
Structural model and prop of the AdolVletDC of
... facilitate this is the characterisation of novel parasite metabolic pathways and their exploitation. The bifunctional S-adenosylmethionine decar boxy lase / Orni thine decar boxy lase (AdoMetD C/ O D C) enzyme, represents one such target. Within this enzyme reside the two main regulatory activities ...
... facilitate this is the characterisation of novel parasite metabolic pathways and their exploitation. The bifunctional S-adenosylmethionine decar boxy lase / Orni thine decar boxy lase (AdoMetD C/ O D C) enzyme, represents one such target. Within this enzyme reside the two main regulatory activities ...
Problem Set Four
... Q6. Streptomycin selection: Can take a plate of StreptS cells and inoculate 50 different cultures, each with a single colony, in nutrient medium. Following growth, you should plate a large number of cells (about 109) from each culture onto a plate with Strept and grow at 37° C. After incubation, yo ...
... Q6. Streptomycin selection: Can take a plate of StreptS cells and inoculate 50 different cultures, each with a single colony, in nutrient medium. Following growth, you should plate a large number of cells (about 109) from each culture onto a plate with Strept and grow at 37° C. After incubation, yo ...
6.2 Assimilation of inorganic nitrogen
... This is an exergonic reaction, but require a high activation energy due to the stable triple bond in N2. Nitrogen fixing microbes produce ‘nitrogenase’ reducing nitrogen under normal physiological conditions. 6.2.1.1.1 Nitrogenase Nitrogenase is a complex protein composed of azoferredoxin and ...
... This is an exergonic reaction, but require a high activation energy due to the stable triple bond in N2. Nitrogen fixing microbes produce ‘nitrogenase’ reducing nitrogen under normal physiological conditions. 6.2.1.1.1 Nitrogenase Nitrogenase is a complex protein composed of azoferredoxin and ...
Molecular Docking Studies of Isorhamnetin from Corchorus olitorius
... postprandial hyperglycemia, by slowing down the absorption of glucose through the inhibition of the carbohydratehydrolyzing enzyme (α–amylase), howbeit with serious side effects. In the present study, with the aid of in silico experiment we have identified isorhamnetin from Corchorus olitorius plant ...
... postprandial hyperglycemia, by slowing down the absorption of glucose through the inhibition of the carbohydratehydrolyzing enzyme (α–amylase), howbeit with serious side effects. In the present study, with the aid of in silico experiment we have identified isorhamnetin from Corchorus olitorius plant ...
Vitamins
... in the formation of hormones, blood cells, nervous-system chemicals and genetic growth. An over dose can be harmful to your health. ...
... in the formation of hormones, blood cells, nervous-system chemicals and genetic growth. An over dose can be harmful to your health. ...
Investigating the Dual Function of the Chloride Intracellular Ion
... I would like to thank my principle supervisor Associate Professor Stella Valenzuela from UTS for her high enthusiasm, dedication and continuous help and support throughout my PhD. Also I would like to express my thankful gratitude to Professor Bruce Cornell from Surgical Diagnostics, Pty, Ltd. I wou ...
... I would like to thank my principle supervisor Associate Professor Stella Valenzuela from UTS for her high enthusiasm, dedication and continuous help and support throughout my PhD. Also I would like to express my thankful gratitude to Professor Bruce Cornell from Surgical Diagnostics, Pty, Ltd. I wou ...
Fatty Acid Catabolism
... Fatty Acid Catabolism March 21, 2003 Bryant Miles Fatty acids are lipids. Fatty acids are also one of the major forms of storage of metabolic energy. There are two distinct advantages in storing metabolic energy as fatty acids. (1) Fatty acids are mainly composed of –CH2- groups which are fully redu ...
... Fatty Acid Catabolism March 21, 2003 Bryant Miles Fatty acids are lipids. Fatty acids are also one of the major forms of storage of metabolic energy. There are two distinct advantages in storing metabolic energy as fatty acids. (1) Fatty acids are mainly composed of –CH2- groups which are fully redu ...
Bio 226: Cell and Molecular Biology
... •NADH, Acetyl CoA, ATP NH4+ inhibit PDH & activate kinase •Activated when no Pi •ADP, pyruvate inhibit kinase ...
... •NADH, Acetyl CoA, ATP NH4+ inhibit PDH & activate kinase •Activated when no Pi •ADP, pyruvate inhibit kinase ...
UvA-DARE (Digital Academic Repository) Bacterial class A acid
... reagents are attractive since they are easily prepared, have a long shelf life, and are easy to handle. However, given the need to generate highly basic alkoxides, reactions are limited to substrates with base-tolerant functional groups. Milder reaction conditions to facilitate this process have bee ...
... reagents are attractive since they are easily prepared, have a long shelf life, and are easy to handle. However, given the need to generate highly basic alkoxides, reactions are limited to substrates with base-tolerant functional groups. Milder reaction conditions to facilitate this process have bee ...
Physical Models for Protein Folding and Drug Design
... that mutations in only few sites denaturate (i.e. impedes its folding) as well as destabilizes (strongly reduces the native state occupation probability) the protein. To be quantitative, we find that only 8% ± 2% (Fig. 1) of the amino acids of a designed sequence are highly conserved, strongly inter ...
... that mutations in only few sites denaturate (i.e. impedes its folding) as well as destabilizes (strongly reduces the native state occupation probability) the protein. To be quantitative, we find that only 8% ± 2% (Fig. 1) of the amino acids of a designed sequence are highly conserved, strongly inter ...