CHEM120 - ORGANIC CHEMISTRY WORKSHEET 1
... Be able to draw by using a perspective formula, Newman projections and Fischer projections. ...
... Be able to draw by using a perspective formula, Newman projections and Fischer projections. ...
11. Reactions of Alkyl Halides
... • The highest energy transition state point on the diagram is that for the rate determining step (which is not always the highest barrier) • This is the not the greatest difference but the absolute highest point (Figures 11.8 – the same step is rate-determining in both directions) ...
... • The highest energy transition state point on the diagram is that for the rate determining step (which is not always the highest barrier) • This is the not the greatest difference but the absolute highest point (Figures 11.8 – the same step is rate-determining in both directions) ...
Zinc Alkyls in Organic Synthesis
... Zinc alkyls, including diethylzinc (DEZ), were first synthesized by Frankland in the 1800’s.[1] It was not until the 1970’s that chemists found a series of their special utility. Work to that period was reviewed by Furukawa and Kawabata.[2] In recent years, interest in zinc alkyls increased signific ...
... Zinc alkyls, including diethylzinc (DEZ), were first synthesized by Frankland in the 1800’s.[1] It was not until the 1970’s that chemists found a series of their special utility. Work to that period was reviewed by Furukawa and Kawabata.[2] In recent years, interest in zinc alkyls increased signific ...
1 1. (20 pts.) Draw the major product of each of the following
... 2. (20 pts.) Design a synthesis of the ketone below. All of the C atoms in the product must be derived from one or both of the two starting materials shown, but you may use any other reagents to accomplish the necessary transformations. Your synthesis will require more than two steps. Show each inte ...
... 2. (20 pts.) Design a synthesis of the ketone below. All of the C atoms in the product must be derived from one or both of the two starting materials shown, but you may use any other reagents to accomplish the necessary transformations. Your synthesis will require more than two steps. Show each inte ...
Ch 16 Aldehydes and Ketones I
... Nucleophilic Addition to the CarbonOxygen Double Bond • Addition of primary and secondary amines – Primary amines react with ald/ket to form imines – An imine has a C-N double bond – Secondary amines react with ald/ket to form enamines – An enamine has an amino group bonded to carboncarbon double b ...
... Nucleophilic Addition to the CarbonOxygen Double Bond • Addition of primary and secondary amines – Primary amines react with ald/ket to form imines – An imine has a C-N double bond – Secondary amines react with ald/ket to form enamines – An enamine has an amino group bonded to carboncarbon double b ...
Syllabus of the International Chemistry Olympiad
... by-product of Dutch cheese making, how whales manage to stay under water for a considerable length of time, how the color of Delft blue pottery can be understood, how a bio-compatible polymer can be made from lactic acid, how modern spectroscopy is applied, how the structure of the natural product c ...
... by-product of Dutch cheese making, how whales manage to stay under water for a considerable length of time, how the color of Delft blue pottery can be understood, how a bio-compatible polymer can be made from lactic acid, how modern spectroscopy is applied, how the structure of the natural product c ...
1 Introduction
... particulates. The third step is impact analysis. First, impact categories are classified. These usually pertain to common environmental threats, such as global warming, acid rain, or ozone depletion. The environmental interventions from step 2 are then translated into scores in each impact category. ...
... particulates. The third step is impact analysis. First, impact categories are classified. These usually pertain to common environmental threats, such as global warming, acid rain, or ozone depletion. The environmental interventions from step 2 are then translated into scores in each impact category. ...
Types of Chemical Reactions
... in the fume hoods. These chemicals are toxic and will harm the environment if not disposed of properly. • Do not eat, drink, or apply the chemicals to skin. Many of these chemicals are highly corrosive and in addition to being toxic, they will burn your skin and muscle tissue. Ouch! • If any of the ...
... in the fume hoods. These chemicals are toxic and will harm the environment if not disposed of properly. • Do not eat, drink, or apply the chemicals to skin. Many of these chemicals are highly corrosive and in addition to being toxic, they will burn your skin and muscle tissue. Ouch! • If any of the ...
Microsoft Word
... Vicinal diols are present in many naturally occurring compounds. The ring opening of epoxides with water in the presence of acid catalysts generates synthetically useful vicdiols. However, most of these epoxide ring opening reactions involve the use of strongly acidic conditions, stoichiometric amou ...
... Vicinal diols are present in many naturally occurring compounds. The ring opening of epoxides with water in the presence of acid catalysts generates synthetically useful vicdiols. However, most of these epoxide ring opening reactions involve the use of strongly acidic conditions, stoichiometric amou ...
Chap Thirteen: Alcohols
... inversion of configuration incomplete iii. SN2 reaction With phosphorus trihalides PBr3 or PCl3 or PCl5 or P° and I2 to form alkyl halides o Mechanism/ no rearrangement/ inversion of configuration e. Alkyl tosylates (sulfonate esters) by reaction of ROH with sulfonyl chlorides i. Mechanism/ retentio ...
... inversion of configuration incomplete iii. SN2 reaction With phosphorus trihalides PBr3 or PCl3 or PCl5 or P° and I2 to form alkyl halides o Mechanism/ no rearrangement/ inversion of configuration e. Alkyl tosylates (sulfonate esters) by reaction of ROH with sulfonyl chlorides i. Mechanism/ retentio ...
Outline_CH13_Klein
... inversion of configuration incomplete iii. SN2 reaction With phosphorus trihalides PBr3 or PCl3 or PCl5 or P° and I2 to form alkyl halides o Mechanism/ no rearrangement/ inversion of configuration e. Alkyl tosylates (sulfonate esters) by reaction of ROH with sulfonyl chlorides i. Mechanism/ retentio ...
... inversion of configuration incomplete iii. SN2 reaction With phosphorus trihalides PBr3 or PCl3 or PCl5 or P° and I2 to form alkyl halides o Mechanism/ no rearrangement/ inversion of configuration e. Alkyl tosylates (sulfonate esters) by reaction of ROH with sulfonyl chlorides i. Mechanism/ retentio ...
Crown ethers
... These compounds are called Crown ethers because their molecule have a crown-like shape. The bracket number represents the ring size and the terminal numbers gives the number of oxygens. The oxygens are usually separated by two ...
... These compounds are called Crown ethers because their molecule have a crown-like shape. The bracket number represents the ring size and the terminal numbers gives the number of oxygens. The oxygens are usually separated by two ...
PREPARATION OF REAGENTS Reagent is a "substance or
... reagent. There are also analytical reagents which are used to confirm the presence of another substance. Examples of these are Fehling's reagent, Millon's reagent and Tollens' reagent. Collins reagent-used to selectively oxidize primary alcohols to an aldehyde Fenton's reagent-solution of hydrogen p ...
... reagent. There are also analytical reagents which are used to confirm the presence of another substance. Examples of these are Fehling's reagent, Millon's reagent and Tollens' reagent. Collins reagent-used to selectively oxidize primary alcohols to an aldehyde Fenton's reagent-solution of hydrogen p ...
thiols and sulfides.
... Ethers are prepared by SN2 reactions. Ethers can be prepared by the reaction of an alkoxide with a primary haloalkane or sulfonate ester under SN2 conditions. The parent alcohol of the alkoxide can be used as the solvent, however other polar solvents are often better, such as DMSO (dimethyl sulfoxid ...
... Ethers are prepared by SN2 reactions. Ethers can be prepared by the reaction of an alkoxide with a primary haloalkane or sulfonate ester under SN2 conditions. The parent alcohol of the alkoxide can be used as the solvent, however other polar solvents are often better, such as DMSO (dimethyl sulfoxid ...
CHAPtER 9 Properties and reactions of organic compounds
... chemicals. Depending on the types of atoms present in compounds, these interactions determine how organic molecules react to produce important chemicals for fuels, pharmaceuticals, manufacturing, industry and biological processes. The number of all the possible organic reactions that can occur is es ...
... chemicals. Depending on the types of atoms present in compounds, these interactions determine how organic molecules react to produce important chemicals for fuels, pharmaceuticals, manufacturing, industry and biological processes. The number of all the possible organic reactions that can occur is es ...
PTT102 Aldehydes and Ketones
... The product of a Claisen condensation is a βketo ester. In a Claisen condensation, one molecule of carbonyl compound is the nucleophile and second molecule is electrophile. The new C-C bond connect the α-carbon of one molecule and the carbon that was formerly the carbonyl carbon of the other m ...
... The product of a Claisen condensation is a βketo ester. In a Claisen condensation, one molecule of carbonyl compound is the nucleophile and second molecule is electrophile. The new C-C bond connect the α-carbon of one molecule and the carbon that was formerly the carbonyl carbon of the other m ...
PTT102 Aldehydes and Ketones
... The product of a Claisen condensation is a βketo ester. In a Claisen condensation, one molecule of carbonyl compound is the nucleophile and second molecule is electrophile. The new C-C bond connect the α-carbon of one molecule and the carbon that was formerly the carbonyl carbon of the other m ...
... The product of a Claisen condensation is a βketo ester. In a Claisen condensation, one molecule of carbonyl compound is the nucleophile and second molecule is electrophile. The new C-C bond connect the α-carbon of one molecule and the carbon that was formerly the carbonyl carbon of the other m ...
Ultrasound Assisted Synthesis of 5,9
... Using citronellol as the starting material, Liang et al. synthesized stereoisomeric mixtures of 1 as well as of 2 in yields of about 25% [6]. Using (R)-citronellol as the starting material, Poppe et al. synthesized 1 as a mixture of the (5S,9S) and (5R,9S) stereoisomeric molecules in a related way i ...
... Using citronellol as the starting material, Liang et al. synthesized stereoisomeric mixtures of 1 as well as of 2 in yields of about 25% [6]. Using (R)-citronellol as the starting material, Poppe et al. synthesized 1 as a mixture of the (5S,9S) and (5R,9S) stereoisomeric molecules in a related way i ...
Synthetic Strategy – Lecture 2 (DC, 19.1.05)
... Lectures 2 through 6 of this third part of the second-year organic synthesis course will be concerned with designing organic syntheses, using the disconnection approach, which as you probably know involves retrosynthetic analysis of target molecules. We will meet a number of new concepts, and encoun ...
... Lectures 2 through 6 of this third part of the second-year organic synthesis course will be concerned with designing organic syntheses, using the disconnection approach, which as you probably know involves retrosynthetic analysis of target molecules. We will meet a number of new concepts, and encoun ...
organic chemistry ii
... A CA derivative can be prepared starting from the more reactive derivative going to less reactive, i.e. esters and/or amides from acid chlorides or anhydrides; amides from esters, etc. Mechanism of Nucleophilic Acyl Substitution When a nucleophile attacks a CA derivative, a tetrahedral intermediate ...
... A CA derivative can be prepared starting from the more reactive derivative going to less reactive, i.e. esters and/or amides from acid chlorides or anhydrides; amides from esters, etc. Mechanism of Nucleophilic Acyl Substitution When a nucleophile attacks a CA derivative, a tetrahedral intermediate ...
Enantioselective synthesis
Enantioselective synthesis, also called chiral synthesis or asymmetric synthesis, is defined by IUPAC as: a chemical reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric (enantiomeric or diastereoisomeric) products in unequal amounts.Put more simply: it is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer.Enantioselective synthesis is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity.