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Epigenetic Clock and Biological Age Steve Horvath, Professor of
Epigenetic Clock and Biological Age Steve Horvath, Professor of

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... This implies q2 = 1/10,000 = 0.0001, or q = 0.01, in excellent agreement with the mutation rate estimated directly from pedigrees and our simple model of mutation-selection equilibrium! But the model fails for CFTR, where the deleterious allele frequency is higher (q ≈ 0.02) and the estimated mutati ...
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userfiles/1290/Genetics Review Sheet - Answer Key

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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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