Modulation of brain activity by electrical stimulation and external
... The basal ganglia, thalamus and motor cortex all play a major role in normal voluntary movement. Even though they have different functions, a disturbance in one of these areas can disrupt the complex interaction network, which can lead to several movement disorders. First indications of the importan ...
... The basal ganglia, thalamus and motor cortex all play a major role in normal voluntary movement. Even though they have different functions, a disturbance in one of these areas can disrupt the complex interaction network, which can lead to several movement disorders. First indications of the importan ...
American Journal of Public Health Research
... processes such as prior memories and it has great influence on enhancing, suppressing or even independently generating a stress response but it is highly susceptible to damage by chronic stress (McEwen, 2012). Another organ of interest in the regulation of cognitive processes is the prefrontal corte ...
... processes such as prior memories and it has great influence on enhancing, suppressing or even independently generating a stress response but it is highly susceptible to damage by chronic stress (McEwen, 2012). Another organ of interest in the regulation of cognitive processes is the prefrontal corte ...
Hydroquinine hydrobromide and hypoglycaemia
... reduces the need for large volumes of intravenous dextrose [3]. ...
... reduces the need for large volumes of intravenous dextrose [3]. ...
Alternative Medications for Medications in the Use of High‐Risk
... Older persons who take multiple drugs with anticholinergic activity, be they strong, moderate, or weak in potency, are at greater risk of physical, functional, and cognitive decline.11 Two types of highly anticholinergic drugs (firstgeneration antihistamines, drugs used for Parkinson’s disease) are ...
... Older persons who take multiple drugs with anticholinergic activity, be they strong, moderate, or weak in potency, are at greater risk of physical, functional, and cognitive decline.11 Two types of highly anticholinergic drugs (firstgeneration antihistamines, drugs used for Parkinson’s disease) are ...
A non-invasive method to relate the timing of neural activity to white
... The neurophysiological basis of variability in the latency of evoked neural responses has been of interest for decades. We describe a method to identify white matter pathways that may contribute to inter-individual variability in the timing of neural activity. We investigated the relation of the lat ...
... The neurophysiological basis of variability in the latency of evoked neural responses has been of interest for decades. We describe a method to identify white matter pathways that may contribute to inter-individual variability in the timing of neural activity. We investigated the relation of the lat ...
Directional guidance of interneuron migration to the cerebral cortex
... understood. Repulsion from the ventricular zone of the subpallium has been suggested to play a role both in the tangential migration of interneurons to the cortex and olfactory bulb (Hu, 1999; Wu et al., 1999; Zhu et al., 1999), as well as in the radial migration of projection neurons into the devel ...
... understood. Repulsion from the ventricular zone of the subpallium has been suggested to play a role both in the tangential migration of interneurons to the cortex and olfactory bulb (Hu, 1999; Wu et al., 1999; Zhu et al., 1999), as well as in the radial migration of projection neurons into the devel ...
Newsletter What’s Inside
... 2012 and Beyond It is hard to believe that another year is fast approaching its end, and by all accounts 2012 has been a very busy and hopefully a successful year for CRS and its members. By all accounts the meeting in Canada was a great success and all who attended had an excellent social and impor ...
... 2012 and Beyond It is hard to believe that another year is fast approaching its end, and by all accounts 2012 has been a very busy and hopefully a successful year for CRS and its members. By all accounts the meeting in Canada was a great success and all who attended had an excellent social and impor ...
CTI - Tech Transfer Central
... Allocation of the 252 drugs approved by the FDA from 1998 - 2007 ...
... Allocation of the 252 drugs approved by the FDA from 1998 - 2007 ...
The Biochemistry of Drug Metabolism
... Since then, many books have appeared, most of them being edited ones offering expertly written reviews; some such books are listed in the References [7 – 20]. Other books were written by one or two authors, their import and tone being more unitarian and didactic (e.g., [21 – 28]). The present Work f ...
... Since then, many books have appeared, most of them being edited ones offering expertly written reviews; some such books are listed in the References [7 – 20]. Other books were written by one or two authors, their import and tone being more unitarian and didactic (e.g., [21 – 28]). The present Work f ...
Phage display for target-based antibacterial drug discovery
... (Ref. 53). These simple phage-display systems are very usethe surface of beads or the wells of a microtiter plate (Step 1). ful for the identification of peptide ligands. However, they Phage from the library are then incubated with the immoare not very useful for larger polypeptides, where the biliz ...
... (Ref. 53). These simple phage-display systems are very usethe surface of beads or the wells of a microtiter plate (Step 1). ful for the identification of peptide ligands. However, they Phage from the library are then incubated with the immoare not very useful for larger polypeptides, where the biliz ...
Normal Thermoregulatory Responses to 3-iodothyronamine, Trace Amines and Amphetamine-like Psychostimulants in
... WI). Following drug treatments, media was removed from the cells and the cells were lysed by the addition of 100 lL of 13 PLB into each well and shaking the plate for 1 hr at room temperature. An aliquot of the lysate (20 lL) from each well was transferred into wells of an opaque 96-well microplate ...
... WI). Following drug treatments, media was removed from the cells and the cells were lysed by the addition of 100 lL of 13 PLB into each well and shaking the plate for 1 hr at room temperature. An aliquot of the lysate (20 lL) from each well was transferred into wells of an opaque 96-well microplate ...
Dr. Pressman`s PowerPoint slides
... Nabbout R, Chiron C. Stiripentol: an example of antiepileptic drug development in childhood epilepsies. ...
... Nabbout R, Chiron C. Stiripentol: an example of antiepileptic drug development in childhood epilepsies. ...
Preferred visually evoked spatial and temporal frequencies in
... impact on the brain and it is therefore debated whether visual properties registered in anesthesia are applicable for the alert state. The aim of this study was therefore to investigate preferences in spatial and temporal frequencies for single units in primary visual cortex in alert rats and compar ...
... impact on the brain and it is therefore debated whether visual properties registered in anesthesia are applicable for the alert state. The aim of this study was therefore to investigate preferences in spatial and temporal frequencies for single units in primary visual cortex in alert rats and compar ...
mecp2 and the epigenetic regulation of excitatory synaptic
... these deficits to the loss of transcriptional repression by MeCP2. By utilizing a conditional knockout approach, we found that these effects were not due to the loss of MeCP2 during neurodevelopment and that they were primarily due to a deficiency in presynaptic vesicle release. We further extended ...
... these deficits to the loss of transcriptional repression by MeCP2. By utilizing a conditional knockout approach, we found that these effects were not due to the loss of MeCP2 during neurodevelopment and that they were primarily due to a deficiency in presynaptic vesicle release. We further extended ...
Antihistamines - Take Control of your Health
... on TV and in magazines. And their use has become widespread, largely eclipsing (but by no means eliminating) the use of first-generation antihistamines. The main reason for their popularity is that they cause less sedation and drowsiness. But these problems can still occur when taking the newer medi ...
... on TV and in magazines. And their use has become widespread, largely eclipsing (but by no means eliminating) the use of first-generation antihistamines. The main reason for their popularity is that they cause less sedation and drowsiness. But these problems can still occur when taking the newer medi ...
Technology Insight: noninvasive brain stimulation in neurology
... result of an initial insult, but also represent the consequences of dynamic, plastic changes in distributed neural networks as the entire nervous system attempts to adapt. This plastic response includes compensatory changes that prove adaptive for the individual, as well as changes that contribute t ...
... result of an initial insult, but also represent the consequences of dynamic, plastic changes in distributed neural networks as the entire nervous system attempts to adapt. This plastic response includes compensatory changes that prove adaptive for the individual, as well as changes that contribute t ...
Cholinergic Deafferentation of the Entorhinal Cortex in Rats
... until they re-established criterion performance. After this time, rats underwent tests with familiar odors to determine whether cholinergic deafferentation of the entorhinal cortex increased sensitivity to increased mnemonic demands produced by prolonged delays between the sample stimuli and choice ...
... until they re-established criterion performance. After this time, rats underwent tests with familiar odors to determine whether cholinergic deafferentation of the entorhinal cortex increased sensitivity to increased mnemonic demands produced by prolonged delays between the sample stimuli and choice ...
Nerve activates contraction
... Functional Classification of Neurons Interneurons (association neurons) Found in neural pathways in the central nervous system Connect sensory and motor neurons ...
... Functional Classification of Neurons Interneurons (association neurons) Found in neural pathways in the central nervous system Connect sensory and motor neurons ...
NEW SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS DETERMINATION OF AMLODIPINE BESYLATE AND ATORVASTATIN CALCIUM IN TABLET DOSAGE FORMS
... method 361nm and 246 nm were selected to measure the absorbance of drugs at both wavelengths. The second method is Q‐value analysis based on measurement of absorptivity at 238.8 nm (as an iso‐absorptive point) and 246 nm. AMD and ATR at their respective maximum wavelength 361 nm and 246 nm and ...
... method 361nm and 246 nm were selected to measure the absorbance of drugs at both wavelengths. The second method is Q‐value analysis based on measurement of absorptivity at 238.8 nm (as an iso‐absorptive point) and 246 nm. AMD and ATR at their respective maximum wavelength 361 nm and 246 nm and ...
Microdose and microtracer information sheet
... dosing at a clinical dose is impractical. Examples are studies with cytotoxic molecules, potent drugs, or drugs with extremely long half-lives where drug and radioactivity exposure to the subject may be a concern. ...
... dosing at a clinical dose is impractical. Examples are studies with cytotoxic molecules, potent drugs, or drugs with extremely long half-lives where drug and radioactivity exposure to the subject may be a concern. ...
OpportunityAnalyzer: Autism Spectrum Disorder - Opportunity Analysis and Forecasts to 2018 Brochure
... target different core and non-core symptoms of ASD. Since this disorder can first become apparent in very young children there is a need for medications which are safe and effective in the pediatric population. The ASD market is expected to grow remain relatively flat between 2012 and 2018, which is ...
... target different core and non-core symptoms of ASD. Since this disorder can first become apparent in very young children there is a need for medications which are safe and effective in the pediatric population. The ASD market is expected to grow remain relatively flat between 2012 and 2018, which is ...
... responsible for the metabolism of many drugs and may also be applied to colon- targeted drug delivery of peptide based macromolecules such as insulin by oral administration. Target sites, colonic disease conditions, and drugs used for treatment are shown in Table 1. 9 Advantages of CDDS over Convent ...
The parental couple relationship in child and adolescent mental health
... memory and synaptic plasticity [8]. Moreover, accumulating evidence suggests that the alterations in miRNAs expression have potential contributions to AD pathophysiology [9]. Hebert et al. investigated alterations in miRNA expression profiles of patients with AD and recognized the miR-29a/ 29b-1 clu ...
... memory and synaptic plasticity [8]. Moreover, accumulating evidence suggests that the alterations in miRNAs expression have potential contributions to AD pathophysiology [9]. Hebert et al. investigated alterations in miRNA expression profiles of patients with AD and recognized the miR-29a/ 29b-1 clu ...
Motor Cognition and Mental Simulation
... representations when we observe a movement or an action and when we produce the corresponding movement or action ourselves. The existence of these shared representations suggests that mental simulations are particularly useful for reasoning about possible actions that you or someone else could take. ...
... representations when we observe a movement or an action and when we produce the corresponding movement or action ourselves. The existence of these shared representations suggests that mental simulations are particularly useful for reasoning about possible actions that you or someone else could take. ...
REVIEWS
... Box 1 | The retinoblastoma protein family: cell cycle control and beyond Members of the retinoblastoma (RB) protein family, comprising RB1 (also known as p105-RB), retinoblastoma-like protein 1 (RBL1; also known as p107) and RBL2 (also known as p130), share sequence homology in a bipartite domain kn ...
... Box 1 | The retinoblastoma protein family: cell cycle control and beyond Members of the retinoblastoma (RB) protein family, comprising RB1 (also known as p105-RB), retinoblastoma-like protein 1 (RBL1; also known as p107) and RBL2 (also known as p130), share sequence homology in a bipartite domain kn ...