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8. Anti-diabetics
8. Anti-diabetics

... the renal tubules exceeding 180 g/dl, threshold for glucose’s reabsorption, leading to the appearance of glucose in the urine (glucosuria). This results in osmotic dragging of water into the tubules resulting in polyuria with subsequent polydypsia. ...
Plasticity-related genes in brain development and amygdala
Plasticity-related genes in brain development and amygdala

The Reflex Arc and Reflexes Lab
The Reflex Arc and Reflexes Lab

... (afferent) neuron. The sensory neuron leads into the central nervous system and may communicate with one or more interneurons. Some of these interneurons, in turn, communicate with motor (efferent) neurons, whose axons (nerve fibers) lead outward to effectors. Thus, when a sensory receptor is stimul ...
GBL
GBL

... Day 1 diazepam 110mg, baclofen 30mg Days 2-4 Diazepam 20mg/day, baclofen 30mg/day Day 4,8 – slept well, feels comfortable, no GBL use Days 10– remained abstinent from GBL. 4 days after ceasing diazepam, began feeling increasing anxiety – not sleeping, depressed, unmotivated. Commenced mirtazapine 15 ...
Cranial Nerves
Cranial Nerves

... muscle of the eye, which also controls the movement of the eye. These axons convey nerve impulses for proprioception. Cranial Nerve V is the trigeminal nerve, and likes its name has 3 branches, ophthalmic, maxillary, and mandibular. This cranial nerve conveys impulses for touch, pain, and temperatur ...
Antibiotics
Antibiotics

... demonstrated this toxicity. Mechanism unclear. ...
exuberance in the development of cortical
exuberance in the development of cortical

... with age in the uptake, transport and diffusion of axonally transported substances that are used to trace them. Some tracers (for example, lipophilic molecules such as carbocyanine dyes) label young, unmyelinated axons well but older, myelinated axons much less effectively. Other tracers tend to be ...
MND Australia Research Meeting 2015 Working towards a world
MND Australia Research Meeting 2015 Working towards a world

... Florey Institute of Neuroscience and Mental Health, University of Melbourne Androgens such as testosterone are essential factors for proper development, growth and survival of motor neurons. Androgens act on the androgen receptor (AR), leading to signalling of gene transcription underlying their tro ...
Self-administration of psychoactive substances by the monkey
Self-administration of psychoactive substances by the monkey

... predictions for man, based upon monkey data, have been proved to be qualitatively accurate. Although physiological dependence is a very important negative reinforcing factor in inducing drug-seeking behavior to avoid the aversive effects of withdrawal, it develops only to substances which have a pre ...
Functional architecture in monkey inferotemporal cortex revealed by
Functional architecture in monkey inferotemporal cortex revealed by

... the ventral visual cortical pathway, optical imaging based on intrinsic signals was carried out. We first conducted single-cell recordings with microelectrodes and determined the features critical for the activation of single cells. For the subsequent optical imaging, each critical feature was prese ...
influence of oxcarbazepine on the antinociceptive action of
influence of oxcarbazepine on the antinociceptive action of

... Pain is a serious burden for the organism. The knowledge of pain, its mechanisms and treatment is very extensive, but despite that it is still insufficient. New analgesics characterized with higher therapeutic efficacy and causing fewer adverse effects are being sought. One of the directions of this ...
N-Methyl-D-Aspartate Receptor Antagonist APV Blocks
N-Methyl-D-Aspartate Receptor Antagonist APV Blocks

... 1986a). In other words, it is a conditional response to conditional stimuli (CS) that are associated with the footshock unconditional stimulus (US; R. J. Blanchard & D. C. Blanchard, 1969; Bolles & Collier, 1976; Fanselow, 1980). Because fear conditioning is a potent form of learning, it must result ...
Behavioral consequences of abnormal cortical development
Behavioral consequences of abnormal cortical development

... developmental disorders. However, the precise relationship between developmental insults and behavioral abnormalities is not fully understood. Do abnormalities in cortical architecture and connectivity, in fact, cause behavioral abnormalities? To best answer this question, it is necessary to explore ...
Optical brain imaging in vivo: techniques and applications from
Optical brain imaging in vivo: techniques and applications from

... This is in addition to serving populations often unable to receive MRI or PET scans such as young infants or the critically ill. Clinical optical brain imaging is generally noninvasive and uses near-infrared 共NIR兲 light to obtain improved penetration through the scalp, skull, and brain 关see Fig. 1共a ...
Neurochemical Enhancement of Conscious Error Awareness
Neurochemical Enhancement of Conscious Error Awareness

... of commission of which they are aware (aware errors) or unaware (unaware errors). Using this task, we have previously examined the neural mechanisms associated with error awareness (Hester et al., 2005; O’Connell et al., 2007), as well as the diminished awareness of performance errors in ADHD (O’Con ...
Brain regions involved in heading estimation and steering control in
Brain regions involved in heading estimation and steering control in

... guided by optic flow, which is defined as the visual motion we perceive as we move through a static environment. This visual motion is created by the surfaces, textures, and contours of our environment; when we walk, these cues will create a radially expanding pattern of motion on our retina and mo ...
Course Objectives
Course Objectives

... Overview of the Cellular Basis of Life o Define cell. o List the three major regions of a generalized cell and indicate the function of each. The Plasma Membrane: Structure o Describe the chemical composition of the plasma membrane and relate it to membrane functions. o Compare the structure and fun ...
neuroanatomy - NC State Veterinary Medicine
neuroanatomy - NC State Veterinary Medicine

... The rostral colliculus in mammals has 7 layers - 3 cellular (strata griseum superficiale, intermediate, and profundus) alternating with 4 of fibers (strata zonale, opticum, album intermediale, and album profundum). Retinotectal fibers generally pass through the stratum opticum, and enter the superfi ...
4 Aromatic Amino Acids in the Brain - Wurtman Lab
4 Aromatic Amino Acids in the Brain - Wurtman Lab

... These enzymes all have high substrate Km’s, hence they have little effect on their amino acid substrates present in systemic blood but major, concentration‐dependent effects on the elevated concentrations, present postprandially, in portal venous blood. All of the large, neutral amino acids (LNAA)—e ...
NIDA - Laurel Business Institute
NIDA - Laurel Business Institute

... Frightening flashbacks (called Hallucinogen Persisting Perception Disorder [HPPD]); ongoing visual disturbances, disorganized thinking, paranoia, and mood swings. ...
PDF
PDF

... that each Petri dish contained a control and a culture containing NGF. The final composition of the culture medium was medium 199, 2 parts, serum or serum containing added NGF, 1 part, and buffered saline, 1 part. The 28 cultures, of which half were controls, were numbered at random and incubated fo ...
Full Article-PDF - Pharma Research Library
Full Article-PDF - Pharma Research Library

... provide protection of drugs, especially proteins that are otherwise rapidly destroyed by the body. Controlled release systems can increase patient comfort and compliance by replacing frequent (e.g., daily) doses with infrequent (once per month or less) injection. One such method is Microspheres as c ...
A scientific theory of ars memoriae: spatial view cells in a continuous
A scientific theory of ars memoriae: spatial view cells in a continuous

... that consist of discrete subsets of active binary firing rate neurons in the range 1,001–1,500. The firing of these latter neurons can be thought of as representing the discrete events that occur at the location. Continuous attractor networks by definition contain only continuous representations, bu ...
evidence based pharmaco- clinical studies on ashwagandha
evidence based pharmaco- clinical studies on ashwagandha

... important hormone precursors that can convert into human physiologic hormones as needed. Ashwagandha is thought to be amphoteric i.e., it can help to regulate important physiologic processes. The theory is that when there is an excess of a certain hormone, the plant-based hormone precursor occupies ...
Numbers-needed-to-treat analysis: an explanation using
Numbers-needed-to-treat analysis: an explanation using

... that individual. A number of authorities, including the National Institute for Health and Clinical Excellence (NICE), recommend that patients are actively involved in treatment decisions, but do not opine on how this can realistically be achieved. Nevertheless, presenting information on treatment in ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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