glial cells as progenitors and stem cells: new roles in the healthy
... and stem cell roles of glial cells in the developing brain, the stage at which the concept that glial cells also act as stem and progenitor cells was originally discovered (166, 185, 198). We shall review the evidence for radial glial cells, the ubiquitous glial cell type in the developing vertebrat ...
... and stem cell roles of glial cells in the developing brain, the stage at which the concept that glial cells also act as stem and progenitor cells was originally discovered (166, 185, 198). We shall review the evidence for radial glial cells, the ubiquitous glial cell type in the developing vertebrat ...
Addition of an angiotensin receptor blocker to full-dose
... whether the same effect is present when full-dose ACEinhibitors are used. Recent data from the Val-HeFT trial indicated a trend towards a more pronounced effect of valsartan in patients with lower doses of the ACE-inhibitor.6 However, this was a non-significant finding in a post hoc The opinions expre ...
... whether the same effect is present when full-dose ACEinhibitors are used. Recent data from the Val-HeFT trial indicated a trend towards a more pronounced effect of valsartan in patients with lower doses of the ACE-inhibitor.6 However, this was a non-significant finding in a post hoc The opinions expre ...
ManuscriptPTA_R1_FINAL - Spiral
... importance, the pathophysiology of post-traumatic amnesia is not understood. Memory processing relies on limbic structures such as the hippocampus, parahippocampus and parts of the cingulate cortex. These structures are connected within an intrinsic connectivity network, the Default Mode Network. In ...
... importance, the pathophysiology of post-traumatic amnesia is not understood. Memory processing relies on limbic structures such as the hippocampus, parahippocampus and parts of the cingulate cortex. These structures are connected within an intrinsic connectivity network, the Default Mode Network. In ...
Potential Part D Drug-Drug Interactions
... Concomitant use of MAOI and SSRI / serotenergic medications are usually contraindicated in most patients. Serious, sometimes fatal reactions may occur, including fever (hyperthermia), rigidity, myoclonus, autonomic instability with possible rapid fluctuation of vital signs and mental status changes ...
... Concomitant use of MAOI and SSRI / serotenergic medications are usually contraindicated in most patients. Serious, sometimes fatal reactions may occur, including fever (hyperthermia), rigidity, myoclonus, autonomic instability with possible rapid fluctuation of vital signs and mental status changes ...
PSUEDOMONAS AERUGINOSA INFECTIONS IN NIGERIA Original Article
... perspectives than societal perspective (See Table 2 for details). Effectiveness Rating Among the routinely used antibacterial agents, the degree of efficacy was highest for ciprofloxacin followed by ceftazidime. The least adherence tendency value was obtained for ceftazidime and gentamicn. Similarly ...
... perspectives than societal perspective (See Table 2 for details). Effectiveness Rating Among the routinely used antibacterial agents, the degree of efficacy was highest for ciprofloxacin followed by ceftazidime. The least adherence tendency value was obtained for ceftazidime and gentamicn. Similarly ...
Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures Zheng Zhou
... and the trifluoromethylphenoxy groups of both fluoxetine enantiomers roughly superimposable, but all three SSRIs have their halogen atoms inserted into the same HBP in LeuT and interact with the same residues (Fig. 2a). Conversely, the difference in their binding lies with the manner in which the ot ...
... and the trifluoromethylphenoxy groups of both fluoxetine enantiomers roughly superimposable, but all three SSRIs have their halogen atoms inserted into the same HBP in LeuT and interact with the same residues (Fig. 2a). Conversely, the difference in their binding lies with the manner in which the ot ...
The neural basis of drug craving: an incentive
... 5.2. The development of addictive behavior. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5.3. Relapse: drug-induced drug craving. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
... 5.2. The development of addictive behavior. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5.3. Relapse: drug-induced drug craving. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
Predicting spike timing of neocortical pyramidal neurons by simple
... 2004). In particular, for single neurons in vitro, it is well known that the intrinsic reliability of neuronal spike timing on a millisecond time scale is highest if the input current has a large fluctuation amplitude, but much lower when the input is constant or shows small fluctuations only (Maine ...
... 2004). In particular, for single neurons in vitro, it is well known that the intrinsic reliability of neuronal spike timing on a millisecond time scale is highest if the input current has a large fluctuation amplitude, but much lower when the input is constant or shows small fluctuations only (Maine ...
Analgesic Best Practice for the Use of Animals in Research and
... the reader should take into account the methods used to determine the level of pain experienced by the animal. Thermal methods include the hot-plate test and the tail flick test. Rodents are placed on a heated surface in the range 50-55°C and their response is noted. The tail flick test uses radiant ...
... the reader should take into account the methods used to determine the level of pain experienced by the animal. Thermal methods include the hot-plate test and the tail flick test. Rodents are placed on a heated surface in the range 50-55°C and their response is noted. The tail flick test uses radiant ...
Orbitofrontal Cortex Encodes Willingness to Pay
... ever food they purchased from us during the task. In addition to a $35 After receiving the instructions, subjects were trained on using the participation fee, each subject received three $1 bills in “spending response boxes with their right hand and on the bidding procedure. To money” to purchase fo ...
... ever food they purchased from us during the task. In addition to a $35 After receiving the instructions, subjects were trained on using the participation fee, each subject received three $1 bills in “spending response boxes with their right hand and on the bidding procedure. To money” to purchase fo ...
Toxicology as a Discipline
... – Use model systems (bacteria, cultured animal cells, DNA interactions) ...
... – Use model systems (bacteria, cultured animal cells, DNA interactions) ...
Dynamics of spontaneous activity in the cerebral cortex across brain states
... d’aquesta tesi per mitjà del servei TDX (www.tdx.cat) i a través del Dipòsit Digital de la UB (diposit.ub.edu) ha estat autoritzada pels titulars dels drets de propietat intel·lectual únicament per a usos privats emmarcats en activitats d’investigació i docència. No s’autoritza la seva reproducció a ...
... d’aquesta tesi per mitjà del servei TDX (www.tdx.cat) i a través del Dipòsit Digital de la UB (diposit.ub.edu) ha estat autoritzada pels titulars dels drets de propietat intel·lectual únicament per a usos privats emmarcats en activitats d’investigació i docència. No s’autoritza la seva reproducció a ...
Cerebral cortex and the clinical expression of
... sex-matched controls. We found close relationships between specific functional and cognitive measures and topologically specific cortical regions. We also found that distinct motor phenotypes were associated with discrete patterns of cortical thinning. The selective topographical associations of cor ...
... sex-matched controls. We found close relationships between specific functional and cognitive measures and topologically specific cortical regions. We also found that distinct motor phenotypes were associated with discrete patterns of cortical thinning. The selective topographical associations of cor ...
New perspectives on the evolution of protochordate sensory and
... (1961) of late larvae and adults. There is, therefore, no evidence as yet to support the claim that the dorsal part of the nerve cord is anything other than primitive, or that amphioxus ever had a signi¢cantly more elaborate complement of sense organs than it does now. Comparing the amphioxus CNS wi ...
... (1961) of late larvae and adults. There is, therefore, no evidence as yet to support the claim that the dorsal part of the nerve cord is anything other than primitive, or that amphioxus ever had a signi¢cantly more elaborate complement of sense organs than it does now. Comparing the amphioxus CNS wi ...
Archives of Medical Research
... hydrogen peroxide is transformed by catalase into water. When an excessive quantity of superoxide radical is produced, it can induce severe tissue damage (17). Several experimental models have been used in order to study the ability of some drugs to eliminate free radicals (13). Among the most frequ ...
... hydrogen peroxide is transformed by catalase into water. When an excessive quantity of superoxide radical is produced, it can induce severe tissue damage (17). Several experimental models have been used in order to study the ability of some drugs to eliminate free radicals (13). Among the most frequ ...
Lateral Hypothalamus Contains Two Types of Palatability
... responses were found within the same regions of LH, cross-correlation analyses suggest that they may participate in distinct functional networks. Our data shed light on the implementation of palatability processing both within LH and throughout the taste circuit, and may ultimately have implications ...
... responses were found within the same regions of LH, cross-correlation analyses suggest that they may participate in distinct functional networks. Our data shed light on the implementation of palatability processing both within LH and throughout the taste circuit, and may ultimately have implications ...
Postnatal characterization of cells in the accessory olfactory bulb of
... et al., 2004) and the simultaneous presentation of odorants and pheromones to the same animal provoke responses from both MOB and AOB (Luo et al., 2003; Xu et al., 2005). This suggests that these two systems might not be as functionally distinct as was originally thought (Meredith, 1991; Baum and Ke ...
... et al., 2004) and the simultaneous presentation of odorants and pheromones to the same animal provoke responses from both MOB and AOB (Luo et al., 2003; Xu et al., 2005). This suggests that these two systems might not be as functionally distinct as was originally thought (Meredith, 1991; Baum and Ke ...
Imaging the premotor areas Nathalie Picard* and Peter L Strick
... In monkeys, it is now established that area 6 on the medial wall of the brain contains two separate areas: the supplementary motor area proper (SMA) in the caudal portion of area 6, and the pre-SMA in the rostral portion (Figure 1a; reviewed in [2,4]). The SMA and pre-SMA are equivalent to fields F3 ...
... In monkeys, it is now established that area 6 on the medial wall of the brain contains two separate areas: the supplementary motor area proper (SMA) in the caudal portion of area 6, and the pre-SMA in the rostral portion (Figure 1a; reviewed in [2,4]). The SMA and pre-SMA are equivalent to fields F3 ...
Neuron
... 2001) and lateral intraparietal areas in macaques (Andersen et al., 1997; Colby and Goldberg, 1999), but functional correspondences among them also remain elusive. These diversities emphasize the importance of direct comparison of the functional architecture of the frontal and parietal eye fields be ...
... 2001) and lateral intraparietal areas in macaques (Andersen et al., 1997; Colby and Goldberg, 1999), but functional correspondences among them also remain elusive. These diversities emphasize the importance of direct comparison of the functional architecture of the frontal and parietal eye fields be ...
Chapter 5 Learning to attend in primary visual cortex
... knowledge, it has not yet been investigated if and how neuronal responses in the visual cortex change as a result of learning within a single recording session. During a single learning session, neurons in frontal cortex change their responses (Chen and Wise 1996; Asaad et al 1998; Yotsumoto et al 2 ...
... knowledge, it has not yet been investigated if and how neuronal responses in the visual cortex change as a result of learning within a single recording session. During a single learning session, neurons in frontal cortex change their responses (Chen and Wise 1996; Asaad et al 1998; Yotsumoto et al 2 ...
Binding and Cytotoxic Effects of Clostdium botulinum Type A, C1
... intraperitoneal injection, 10 LD5o ml-l (250 pg ml-l) of toxin was used; 0.5 mI of the mixtures was injected and the mice were observed for 6 d. For intravenous injection, 2 x lo5 LDS0ml-l (5 pg ml-l) was used, and 0.1 ml of the mixtures was injected. The average time to death and the percentage of ...
... intraperitoneal injection, 10 LD5o ml-l (250 pg ml-l) of toxin was used; 0.5 mI of the mixtures was injected and the mice were observed for 6 d. For intravenous injection, 2 x lo5 LDS0ml-l (5 pg ml-l) was used, and 0.1 ml of the mixtures was injected. The average time to death and the percentage of ...
Manual-Based Treatment: Evolution and Evaluation
... of any clinical disorder. Of particular practical significance is the finding that early response to treatment has emerged as a robust predictor of subsequent treatment outcome—not only in depression, but also in other disorders (Wilson, 1999; see the example of eating disorders discussed later in t ...
... of any clinical disorder. Of particular practical significance is the finding that early response to treatment has emerged as a robust predictor of subsequent treatment outcome—not only in depression, but also in other disorders (Wilson, 1999; see the example of eating disorders discussed later in t ...
ANS: c, p. 46, F, LO=2.1, (1)
... ANS: a, pp. 46–47, C, LO=2.1, (2) APA=1.1 14. Your teacher asks you to describe the sequence of parts of a neuron that the impulse travels during neural conduction. Which of the following sequences will you offer? a) dendrites, axon, soma, synaptic knob b) terminal buttons, axon, soma, dendrites c) ...
... ANS: a, pp. 46–47, C, LO=2.1, (2) APA=1.1 14. Your teacher asks you to describe the sequence of parts of a neuron that the impulse travels during neural conduction. Which of the following sequences will you offer? a) dendrites, axon, soma, synaptic knob b) terminal buttons, axon, soma, dendrites c) ...
Endocrine disrupting substances
... here is a current concern that an increasing number of substances, with possible endocrine disrupting potential, are being released into the environment and that these substances may have deleterious effects on vertebrate reproduction. Possible links between disturbed reproduction and exposure to en ...
... here is a current concern that an increasing number of substances, with possible endocrine disrupting potential, are being released into the environment and that these substances may have deleterious effects on vertebrate reproduction. Possible links between disturbed reproduction and exposure to en ...
PPT - Leibniz Institute for Age Research
... effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely. Phase IV: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and ...
... effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely. Phase IV: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and ...