PDF - Oxford Academic - Oxford University Press
... retract many times a minute (Dailey and Smith, 1996). Realtime imaging of dendritic growth in hippocampal slices using time-lapse confocal microscopy shows that dendritic growth is dependent on stabilization of a subset of many highly motile and protrusive dendritic structures (Dailey and Smith, 19 ...
... retract many times a minute (Dailey and Smith, 1996). Realtime imaging of dendritic growth in hippocampal slices using time-lapse confocal microscopy shows that dendritic growth is dependent on stabilization of a subset of many highly motile and protrusive dendritic structures (Dailey and Smith, 19 ...
Effects of insulin under normal and low glucose on retinal
... Results. Insulin failed to affect retinal signals at normal glucose levels. However, insulin enhanced the low glucose-induced decrease in rod-driven b-wave amplitude (P < 0.05 at 2 mM; P < 0.01 at 1 mM) without affecting the corresponding changes in the optic nerve response. The standing potential i ...
... Results. Insulin failed to affect retinal signals at normal glucose levels. However, insulin enhanced the low glucose-induced decrease in rod-driven b-wave amplitude (P < 0.05 at 2 mM; P < 0.01 at 1 mM) without affecting the corresponding changes in the optic nerve response. The standing potential i ...
The placebo effect in Parkinson`s disease
... in fact an expectation [8,18,19]. Many medical conditions are susceptible to the placebo effect [3,4]. Although a recent meta-analysis has called its importance into question [20], new evidence supporting the expectation theory of the placebo effect suggests that the studies included in this analysi ...
... in fact an expectation [8,18,19]. Many medical conditions are susceptible to the placebo effect [3,4]. Although a recent meta-analysis has called its importance into question [20], new evidence supporting the expectation theory of the placebo effect suggests that the studies included in this analysi ...
Anatomofunctional organization of the ventral primary motor and
... The ventral agranular frontal cortex of the macaque monkey is formed by a mosaic of anatomically distinct areas. Although each area has been explored by several neurophysiological studies, most of them focused on small sectors of single areas, thus leaving to be clarified which is the general anatom ...
... The ventral agranular frontal cortex of the macaque monkey is formed by a mosaic of anatomically distinct areas. Although each area has been explored by several neurophysiological studies, most of them focused on small sectors of single areas, thus leaving to be clarified which is the general anatom ...
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[Salvia divinorum - a potential drug for abuse]
... Selective kappa receptoragonists have been shown to produce analgesic effects with potential for reduced tolerance and dependence. However, psychotomimesis (hallucinogenic and/or psychotic effects), dysphoria and diuresis have been observed with their therapeutic use (Tidgewell et aI., 2004). In add ...
... Selective kappa receptoragonists have been shown to produce analgesic effects with potential for reduced tolerance and dependence. However, psychotomimesis (hallucinogenic and/or psychotic effects), dysphoria and diuresis have been observed with their therapeutic use (Tidgewell et aI., 2004). In add ...
Evaluation of Hepatic Glutathione Transferase Mu 1 and Theta 1
... in paired neoplastic and adjacent non-neoplastic liver tissue (Kirby et al., 1993) and to determine the extent of variation in GST activity toward aflatoxin B1-8,9-epoxide, which is a reactive metabolite of aflatoxin B1 (Slone et al., 1995). Decreases in GST-Alpha and GST-Mu and an increase in GST-P ...
... in paired neoplastic and adjacent non-neoplastic liver tissue (Kirby et al., 1993) and to determine the extent of variation in GST activity toward aflatoxin B1-8,9-epoxide, which is a reactive metabolite of aflatoxin B1 (Slone et al., 1995). Decreases in GST-Alpha and GST-Mu and an increase in GST-P ...
15. Recent Trends in Sustained Release Drug Delivery System
... forms such as solutions, ointments, tablets and capsules.1 Delayed Release These systems are those that use repetitive, intermittent dosing of a drug from one or more immediate release units incorporated into a single dosage form. Examples of delayed release systems include repeat action tablets and ...
... forms such as solutions, ointments, tablets and capsules.1 Delayed Release These systems are those that use repetitive, intermittent dosing of a drug from one or more immediate release units incorporated into a single dosage form. Examples of delayed release systems include repeat action tablets and ...
Effect of Oxidative Stress on AhpC Activity and Virulence in katG
... phenotypic properties (catalase activity and AhpC activity). AhpC activity of katG Ser315Thr M.tuberculosis strains in response to oxidative stress condition was evaluated by culturing the strains on liquid culture medium containing 1mM H2O2. To ascertain role of AhpC in the virulence of katGSer315T ...
... phenotypic properties (catalase activity and AhpC activity). AhpC activity of katG Ser315Thr M.tuberculosis strains in response to oxidative stress condition was evaluated by culturing the strains on liquid culture medium containing 1mM H2O2. To ascertain role of AhpC in the virulence of katGSer315T ...
Alprazolam - The National Advanced Driving Simulator
... significantly impaired by alprazolam. Alprazolam also increased reaction time significantly in the Sternberg memory scanning task. After taking alprazolam, six of the twenty participants fell asleep while attempting to complete the on-road driving task. No participants fell asleep after taking place ...
... significantly impaired by alprazolam. Alprazolam also increased reaction time significantly in the Sternberg memory scanning task. After taking alprazolam, six of the twenty participants fell asleep while attempting to complete the on-road driving task. No participants fell asleep after taking place ...
Author`s personal copy - Texas Christian University
... suppression because animals tend to avoid stimuli associated with negative emotional content, such as the area where they have consumed the devalued sucrose solution (i.e., secondary frustration; [5,10]). The research reported here is concerned with the encoding of this aversive memory of the downsh ...
... suppression because animals tend to avoid stimuli associated with negative emotional content, such as the area where they have consumed the devalued sucrose solution (i.e., secondary frustration; [5,10]). The research reported here is concerned with the encoding of this aversive memory of the downsh ...
Brain oscillations and memory - Wellcome Trust Centre for
... MEG (e.g. [57]). This could potentially enable noninvasive decoding of large-scale neural activity with high temporal resolution. In one MEG study, MVPC analysis detected replay of encoded stimulus features during maintenance [57]. Replay was specific to whether the maintained stimulus depicted an i ...
... MEG (e.g. [57]). This could potentially enable noninvasive decoding of large-scale neural activity with high temporal resolution. In one MEG study, MVPC analysis detected replay of encoded stimulus features during maintenance [57]. Replay was specific to whether the maintained stimulus depicted an i ...
The contribution of sleep to hippocampus
... strengthened explicit aspects of a memory representation at the expense of implicit aspects [26]. Although subjects in this study remained unaware of the underlying sequence structure of the task during training before sleep, only after post-learning sleep did they develop explicit sequence knowledg ...
... strengthened explicit aspects of a memory representation at the expense of implicit aspects [26]. Although subjects in this study remained unaware of the underlying sequence structure of the task during training before sleep, only after post-learning sleep did they develop explicit sequence knowledg ...
Interactions between frontal cortex and basal ganglia in working
... Deniau (and was suggested earlier by others; Neafsey, Hull, & Buchwald, 1978; Schneider, 1987), this disinhibition produces a gating function (this is literally the term they used): It enables other functions to take place but does not directly cause them to occur, as a direct excitatory connection ...
... Deniau (and was suggested earlier by others; Neafsey, Hull, & Buchwald, 1978; Schneider, 1987), this disinhibition produces a gating function (this is literally the term they used): It enables other functions to take place but does not directly cause them to occur, as a direct excitatory connection ...
LITERATURE REVIEW Drug Review
... significantly impaired by alprazolam. Alprazolam also increased reaction time significantly in the Sternberg memory scanning task. After taking alprazolam, six of the twenty participants fell asleep while attempting to complete the on-road driving task. No participants fell asleep after taking place ...
... significantly impaired by alprazolam. Alprazolam also increased reaction time significantly in the Sternberg memory scanning task. After taking alprazolam, six of the twenty participants fell asleep while attempting to complete the on-road driving task. No participants fell asleep after taking place ...
Similarities between Severe Tinnitus and Chronic Pain
... from those mediating sensory information. Acute pain may be caused by injuries of various kinds and inflammatory processes may cause pain that lasts a long time . This kind of pain information is mediated by specific pain receptors and carried in neural pathways that are separate from those carrying ...
... from those mediating sensory information. Acute pain may be caused by injuries of various kinds and inflammatory processes may cause pain that lasts a long time . This kind of pain information is mediated by specific pain receptors and carried in neural pathways that are separate from those carrying ...
Whisker movements evoked by stimulation of single pyramidal cells
... Neuronal activity in the motor cortex is understood to be correlated with movements, but the impact of action potentials (APs) in single cortical neurons on the generation of movement has not been fully determined. Here we show that trains of APs in single pyramidal cells of rat motor cortex can evo ...
... Neuronal activity in the motor cortex is understood to be correlated with movements, but the impact of action potentials (APs) in single cortical neurons on the generation of movement has not been fully determined. Here we show that trains of APs in single pyramidal cells of rat motor cortex can evo ...
UNIVERSITY OF KENTUCKY
... 50. The nurse knows that the MOA of all of the diuretic agents is that they lower B/P by: A. decreasing cardiac output by increasing both sodium and water excretion B. decreasing peripheral vascular resistance by decreasing the amount of water in the body C. depressing the sympathetic nervous system ...
... 50. The nurse knows that the MOA of all of the diuretic agents is that they lower B/P by: A. decreasing cardiac output by increasing both sodium and water excretion B. decreasing peripheral vascular resistance by decreasing the amount of water in the body C. depressing the sympathetic nervous system ...
Quantitative assessment of neurite outgrowth in human
... were obtained from ArunA Biomedical, Inc. (Athens, GA). The growth substrates poly-L-lysine and laminin were purchased from Sigma–Aldrich (St. Louis, MO). Bisindolylmaleimide I (Bis1) and brefeldin A were purchased from Calbiochem, Inc. (San Diego, CA). ...
... were obtained from ArunA Biomedical, Inc. (Athens, GA). The growth substrates poly-L-lysine and laminin were purchased from Sigma–Aldrich (St. Louis, MO). Bisindolylmaleimide I (Bis1) and brefeldin A were purchased from Calbiochem, Inc. (San Diego, CA). ...
Morphine effects on monetary reward - DUO
... The µ-opioid receptor system is central to reward and pain relief across species. In rodents, injection of opioids into striatum amplifies ‘liking’ responses to and/or motivation for rewards. In humans, opioid agonists can induce euphoria, whereas antagonists reduce food reward. Brain regions implic ...
... The µ-opioid receptor system is central to reward and pain relief across species. In rodents, injection of opioids into striatum amplifies ‘liking’ responses to and/or motivation for rewards. In humans, opioid agonists can induce euphoria, whereas antagonists reduce food reward. Brain regions implic ...
Accelerating axonal growth promotes motor
... Tubb2a, Sprr1a, Fn14, Ndel1, and Trpc4, as well as several regeneration-promoting transcription factors, Atf3, c-Jun, Stat3, and Sox11 (11). Although these proteins individually increase axonal growth, none thus far have been shown to produce functional recovery (Supplemental Table 1; supplemental m ...
... Tubb2a, Sprr1a, Fn14, Ndel1, and Trpc4, as well as several regeneration-promoting transcription factors, Atf3, c-Jun, Stat3, and Sox11 (11). Although these proteins individually increase axonal growth, none thus far have been shown to produce functional recovery (Supplemental Table 1; supplemental m ...
Discrete coding of stimulus value, reward expectation, and reward
... Electrolytic lesions were made by passing electrical current through the tip of the electrode and into ...
... Electrolytic lesions were made by passing electrical current through the tip of the electrode and into ...
SAD Kinases Sculpt Axonal Arbors of Sensory Neurons through
... Thus, in brainstem as in spinal cord, IaPSNs axons grow to the vicinity of their target, but fail to form terminal branches. Second, we used DiI to label central projections of trigeminal sensory neurons that innervate whiskers. These axons grow to the brainstem where they arborize in nuclei of the ...
... Thus, in brainstem as in spinal cord, IaPSNs axons grow to the vicinity of their target, but fail to form terminal branches. Second, we used DiI to label central projections of trigeminal sensory neurons that innervate whiskers. These axons grow to the brainstem where they arborize in nuclei of the ...
DO YOU SENSE WHAT I SENSE?
... world by using information that it receives from your eyes, ears, nose, mouth, and skin. Throughout this workbook, you will find neuroscience-inspired hands-on activities. We selected these activities from a wide range of possible activities described on neuroscience websites because they were relat ...
... world by using information that it receives from your eyes, ears, nose, mouth, and skin. Throughout this workbook, you will find neuroscience-inspired hands-on activities. We selected these activities from a wide range of possible activities described on neuroscience websites because they were relat ...