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Information processing in the cortex: The relevance of coherent oscillations for neuronal communication
Information processing in the cortex: The relevance of coherent oscillations for neuronal communication

... rents on pyramidal neurons, suggesting that interneuronal synchronization was mediated by fast recurrent excitation. Therefore, cholinergically induced fast network oscillations in the hippocampus appeared to be generated by a synaptic feedback circuit between pyramidal cells and perisomatic-targeti ...
Activities of SYK and PLCγ2 Predict Apoptotic Response of CLL
Activities of SYK and PLCγ2 Predict Apoptotic Response of CLL

... that is clinically available for the treatment of chronic myelogenous leukemia (CML) patients with resistance or intolerance to previous therapy. As an SRC inhibitor, dasatinib binds to SRC kinase family members with high affinity. The KD for in vitro binding is in the nanomolar range (17), and an i ...
Suggested APA style reference: National Institute on Drug Abuse
Suggested APA style reference: National Institute on Drug Abuse

... Hyperthermia (elevated body temperature) and convulsions may occur with methamphetamine overdose, and if not treated immediately, can result in death. Most of the pleasurable effects of methamphetamine are believed to result from the release of very high levels of the neurotransmitter dopamine. Dopa ...
Cliff - USD Biology
Cliff - USD Biology

...  Suppression of NAc Shell neural activity → ↑Feeding ...
Sustained release drug delivery system
Sustained release drug delivery system

... form is controlled mainly by the type and proportion of polymer used in the reparations. Hydrophilic polymer matrix is widely used for formulating an SR dosage form2-5. Because of increased complication and expense involved in marketing of new drug entities, has focused greater attention on developm ...
Predictions not commands: active inference in the motor system
Predictions not commands: active inference in the motor system

... error. We discuss how active inference could have important implications for the organisation of the motor system, and illustrate the implicit mechanisms using the classical ‘knee-jerk’ reflex. The active inference view differs from the conventional (computational) views of motor control in conceptu ...
Getting to Know You: Reputation and Trust in a Two
Getting to Know You: Reputation and Trust in a Two

... To probe neural substrates of social interactions, we scan the brains of multiple subjects engaged in a social interaction. Social decision-making critically depends on internally represented models of social partners. In principle, such covert knowledge might be inferred from behavioral observation ...
Neural Correlates of Vibrissa Resonance: Band
Neural Correlates of Vibrissa Resonance: Band

... These findings suggest several parallels between frequency processing in the vibrissa system and the auditory system and have important implications for detection and discrimination of tactile information. Introduction The vibrissa sensory system of rats is capable of highresolution tactile discrimi ...
Anatomical Distribution of Serotonin- Containing
Anatomical Distribution of Serotonin- Containing

... By using a monoclonal antibody to serotonin (5-HT), an immunohistochemical study was undertaken to provide a comprehensive description of the 5-HT-containing neurons and of the distribution of their axonal processes in the cat brain and spinal cord. The localization of cell bodies was comparable to ...
Duration Tuning across Vertebrates
Duration Tuning across Vertebrates

... that neural inhibition is necessary for creating DTNs in the IC. Blocking receptors of inhibitory neurotransmitters via neuropharmacological agents abolishes or greatly diminishes duration-tuned responses (Fuzessery and Hall, 1999; Jen and Feng, 1999; Casseday et al., 2000; Jen and Wu, 2005; Yin et ...
SEMINAR ON BUCCAL DRUG DELIVERY SYSTUM
SEMINAR ON BUCCAL DRUG DELIVERY SYSTUM

... Two types of permeability cells have been used: side-by-side horizontal (i.e., Ussing-type) and vertical (i.e., Franztype).  Diffusion cells are very useful to measure the transmembrane flux of a substance across a mucosa and to study the effects of absorption enhancers on the membrane.  well-defi ...
The Drosophila Pox neuro gene: control of male courtship behavior
The Drosophila Pox neuro gene: control of male courtship behavior

... Single choice courting tests were performed at room temperature in a modified 24-well microtiter plate (15×8 mm wells covered with microscope glass slides), which was placed in a tray humidified with wet filter paper. All tests were performed at room temperature either under daylight or in a darkroo ...
Comparison of Primate Prefrontal and Inferior Temporal
Comparison of Primate Prefrontal and Inferior Temporal

... were created by linear combinations of these vectors added to that prototype. For more information see http://www.ai.mit.edu/projects/cbcl/ morph. By morphing different amounts of the prototypes we could generate thousands of Figure 1. Organization of stimulus set. A, The 6 prototype images and 15 m ...
Bionic Brain is a Potentiated Novel Therapy for Cardiovascular
Bionic Brain is a Potentiated Novel Therapy for Cardiovascular

... vasomotor center modulates the sympathetic outflow depending on the inputs from the baroreceptors. The efferent sympathetic nerve firing facilitates the cardiovascular actuators and induces resultant AP change. This negative feedback loop is the biological mechanism that stabilizes AP. Previous many ...
NIH Public Access
NIH Public Access

... O'Neill and Suga 1979, Suga et al., 1979; Myotis lucifugus, Sullivan 1982a,b; Eptesicus fuscus, Dear et al., 1993; Feng et al., 1978), Rhinolophus rouxi, Schuller et al., 1988, 1991; Carollia perspicillata, Hagemann et al., 2010). In most of these species, the delay-tuned neurons respond to the same ...
Making Mirrors: Premotor Cortex Stimulation
Making Mirrors: Premotor Cortex Stimulation

... of the timing of the influence of PMv on M1 during mirror motor facilitation. Moreover, the same technique can be used to compare the influence exerted by PMv and PMd. In paired-pulse TMS, a conditioning pulse is applied to the brain area under investigation. This areaʼs task-related influence on M1 ...
Ictal SPECT in patients with rapid eye movement
Ictal SPECT in patients with rapid eye movement

... 60% of all narcoleptic patients. Whether rapid eye movement sleep behaviour disorder is also a predictor for neurodegeneration in narcolepsy is not known. Although the pathophysiology causing the disinhibition of muscle tone in rapid eye movement sleep behaviour disorder has been studied extensively ...
Guideline Update - American Academy of Sleep Medicine
Guideline Update - American Academy of Sleep Medicine

... should meet the needs of most patients in most situations. These guidelines should not, however, be considered inclusive of all proper methods of care or exclusive of other methods of care reasonably expected to obtain the same results. The ultimate judgment regarding appropriateness of any specific ...
XOMA 358, a Novel Treatment for Hyperinsulinemic Hypoglycemia
XOMA 358, a Novel Treatment for Hyperinsulinemic Hypoglycemia

... 358 appeared to be well-tolerated; there were no serious adverse events or severe adverse events. 11/14 subjects experienced adverse events. All drug-related adverse events were mild (43/46) or moderate (3/46), and none required either concomitant medication or invasive procedures for management. Th ...
Autometallographic Tracing of Bismuth in Human Brain Autopsies
Autometallographic Tracing of Bismuth in Human Brain Autopsies

... (13). Axonal transport of silver and mercury has previously been shown to take place (19–22). This transport mechanism of toxic metals is important from a toxicological point of view in that it represents a pathway of entry into the CNS that circumvents the blood-brain barrier. However, bismuth upta ...
Poster presentation
Poster presentation

... non-compliance with the guidelines, especially the reasons for prescribing or not prescribing methyldopa, short-acting nifedipine and reserpine. The interview sessions were audio taped and the transcripts transcribed by two researchers (independently). Results: Overall, participants were ambivalent ...
Aalborg Universitet Brain plasticity Wang, Li
Aalborg Universitet Brain plasticity Wang, Li

... subjective pain perception (Mullins et al., 2005). Hence, activation change of the mechanisms involved in cortical reorganization can reflect the status of the underlying mechanisms in cortical or subcortical structures. In general, studies investigating cortical plasticity have focused on the reorg ...
Inhaled  loop  diuretics  as  potential ... asthmatic  drugs - *
Inhaled loop diuretics as potential ... asthmatic drugs - *

... challenge with sodium metabisulphite and adenosine [23- 25]. The mechanism of action of these bronchoconstrictor agents is still unknown, but is considered to be, at least partially, mediated by nerve and mast cell activation. In contrast, the bronchoconstrictor activity of methacholine, histamine a ...
Modifying effects of boswellia carteri on clarithromycine action: In
Modifying effects of boswellia carteri on clarithromycine action: In

... of clarithromycine ranged from 4mg/ml for Pseudomonas aeruginosa and 19mm toward Klebsiella pneumonia while zone of inhibition of Boswellia carteri ranged from 6mmfor Pseudomonas aeruginosa to 14mm for Klebsiella pneumonia the p value was insignificant p ˃0.05 but the combined mixture showed signifi ...
Age-related naturally occurring depression of
Age-related naturally occurring depression of

... van Praag et al., 2002; Ambrogini et al., 2004a). The occurrence of neurogenesis in the hippocampus suggests its possible role in hippocampal function (Gould et al., 1999b). Shors et al. used a model of neural precursor proliferation depression induced by the cytostatic agent methylazoxymethanol (MA ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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