Multisensory Integration in the Ventral Intraparietal Area of the
... responses (V for visual, T for tactile) (King and Palmer, 1985; Populin and Yin, 2002; Perrault et al., 2005, their “multisensory contrast index”): Index2 ⫽ [(Bi ⫺ (V ⫹ T))/(V ⫹ T)] ⫻ 100. In this study, we chose to use both indices because they provide complementary information. However, we introdu ...
... responses (V for visual, T for tactile) (King and Palmer, 1985; Populin and Yin, 2002; Perrault et al., 2005, their “multisensory contrast index”): Index2 ⫽ [(Bi ⫺ (V ⫹ T))/(V ⫹ T)] ⫻ 100. In this study, we chose to use both indices because they provide complementary information. However, we introdu ...
Analysis of sleep spindles and model of their generation
... Sleep spindles are present in the sleep EEG from infancy throughout life until old age. Their morphology changes with age reflecting changes in brain connectivity. Spindles develop in humans at 6 weeks after birth at first at low amplitude, gradually increasing in amplitude but especially in duratio ...
... Sleep spindles are present in the sleep EEG from infancy throughout life until old age. Their morphology changes with age reflecting changes in brain connectivity. Spindles develop in humans at 6 weeks after birth at first at low amplitude, gradually increasing in amplitude but especially in duratio ...
Phasic Activation of Individual Neurons in the Locus Ceruleus
... Neurons in the brainstem nucleus locus ceruleus (LC) often exhibit phasic activation in the context of simple sensory-motor tasks. The functional role of this activation, which leads to the release of norepinephrine throughout the brain, is not yet understood in part because the conditions under whi ...
... Neurons in the brainstem nucleus locus ceruleus (LC) often exhibit phasic activation in the context of simple sensory-motor tasks. The functional role of this activation, which leads to the release of norepinephrine throughout the brain, is not yet understood in part because the conditions under whi ...
Predominance of Movement Speed Over Direction in Neuronal
... Stegun 1970) from the recorded position. All kinematic variables were normalized to their standard deviation (SD) and smoothed (eighth order Butterworth with 10-Hz cut-off frequency and zero-phase shift), with the exception of movement direction. The directional vector was derived by normalization t ...
... Stegun 1970) from the recorded position. All kinematic variables were normalized to their standard deviation (SD) and smoothed (eighth order Butterworth with 10-Hz cut-off frequency and zero-phase shift), with the exception of movement direction. The directional vector was derived by normalization t ...
NSAIDs Guidelines
... Long-term use of NSAIDs in cats NSAIDs and cats Non-steroidal anti-inflammatory drugs (NSAIDs) are an important class of drug in feline medicine, having analgesic, anti-inflammatory and antipyretic activity. While most published data on their use in this species relate to short-term (often periopera ...
... Long-term use of NSAIDs in cats NSAIDs and cats Non-steroidal anti-inflammatory drugs (NSAIDs) are an important class of drug in feline medicine, having analgesic, anti-inflammatory and antipyretic activity. While most published data on their use in this species relate to short-term (often periopera ...
Selective Cox-2 Inhibitor
... COX-1 and COX-2.1 COX-l has been found to be constitutively expressed in most tissues of the human body and provides prostaglandins with a role in the homeostatic functions, including affecting gastric mucosa, renal blood flow, hemostasis, wound healing, and ovulation.(4)*By contrast, COX-2 maintain ...
... COX-1 and COX-2.1 COX-l has been found to be constitutively expressed in most tissues of the human body and provides prostaglandins with a role in the homeostatic functions, including affecting gastric mucosa, renal blood flow, hemostasis, wound healing, and ovulation.(4)*By contrast, COX-2 maintain ...
Daptomycyin Review
... myalgia of the hands, wrists and/or forearms, was reported. Mobility was not affected, and no changes occurred in vibratory sensation or electromyography. CPK levels peaked at 10 000–20 000 U/L 1 day after daptomycin was discontinued and approached baseline about 1 week later. All signs of muscle to ...
... myalgia of the hands, wrists and/or forearms, was reported. Mobility was not affected, and no changes occurred in vibratory sensation or electromyography. CPK levels peaked at 10 000–20 000 U/L 1 day after daptomycin was discontinued and approached baseline about 1 week later. All signs of muscle to ...
Dendritic Computation - UCSD Cognitive Science
... summation is achieved by the mutual shunting of the excitatory inputs, and the threshold is implemented via the spike-generation mechanism. (C ) Neurons are known to be involved in much more sophisticated computations, such as face recognition (Kreiman et al. 2000). An algorithm to solve a face reco ...
... summation is achieved by the mutual shunting of the excitatory inputs, and the threshold is implemented via the spike-generation mechanism. (C ) Neurons are known to be involved in much more sophisticated computations, such as face recognition (Kreiman et al. 2000). An algorithm to solve a face reco ...
Reviews Essential Tremor - Tremor and Other Hyperkinetic
... The pathophysiology of essential tremor (ET) is only partially understood. There is some understanding of culpable macro-circuitry, mostly based on functional positron emission tomography (PET)/singlephoton emission computed tomography studies, functional magnetic resonance imaging, tractography, tr ...
... The pathophysiology of essential tremor (ET) is only partially understood. There is some understanding of culpable macro-circuitry, mostly based on functional positron emission tomography (PET)/singlephoton emission computed tomography studies, functional magnetic resonance imaging, tractography, tr ...
Fluorescence Recordings of Electrical Activity in Goldfish Optic
... Preparation. An in vitro slice preparation of the goldfish optic tectum (Freeman, 1979a, b; Matsumoto et al., 1983) was employed. Goldfish were anesthetized by immersion in ice water. When all movement ceased, the fish were placed on the stage of a dissecting microscope and the cranial cavity fully ...
... Preparation. An in vitro slice preparation of the goldfish optic tectum (Freeman, 1979a, b; Matsumoto et al., 1983) was employed. Goldfish were anesthetized by immersion in ice water. When all movement ceased, the fish were placed on the stage of a dissecting microscope and the cranial cavity fully ...
Effects of oral phentolamine, taken before sleep, on nocturnal
... Padma-Nathan et al; in those men who began ICI therapy less than 300 days after radical surgery, 73% reported return to spontaneous erections, compared to 35% of those who began ICI more than 300 days after radical prostatectomy, demonstrating the devastating results of long lasting corporal ischemi ...
... Padma-Nathan et al; in those men who began ICI therapy less than 300 days after radical surgery, 73% reported return to spontaneous erections, compared to 35% of those who began ICI more than 300 days after radical prostatectomy, demonstrating the devastating results of long lasting corporal ischemi ...
Action Preparation Shapes Processing in Early Visual Cortex
... Departments of 1Psychiatry, 2Radiology, and 3Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3508 GA, Utrecht, the Netherlands, 4Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behavior, 6525 HR, Nijmegen, the Netherlands, and 5Department of Exper ...
... Departments of 1Psychiatry, 2Radiology, and 3Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, 3508 GA, Utrecht, the Netherlands, 4Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behavior, 6525 HR, Nijmegen, the Netherlands, and 5Department of Exper ...
Tang et al - Pro Aid Autisme
... decline during late childhood and adolescence to adult levels (Penzes et al., 2011), a process that provides selection and maturation of synapses and neural circuits. While ASDs exhibit striking genetic and clinical heterogeneity, multiple ASD syndromes are caused by mutations in genes that act to i ...
... decline during late childhood and adolescence to adult levels (Penzes et al., 2011), a process that provides selection and maturation of synapses and neural circuits. While ASDs exhibit striking genetic and clinical heterogeneity, multiple ASD syndromes are caused by mutations in genes that act to i ...
Pharmaceuticals - Sites @ Suffolk University
... considerably, the consumer should feel free to choose the lowest-cost aspirin. ...
... considerably, the consumer should feel free to choose the lowest-cost aspirin. ...
Isoform-specific expression and function of neuregulin
... impair development of the myocardium, which is the likely cause of death of mutant embryos on day 10.5 of development (Meyer and Birchmeier, 1995; Kramer et al., 1996). In the myocardium, similar defects are observed in animals that lack erbB4, whereas the development of cranial ganglia is affected ...
... impair development of the myocardium, which is the likely cause of death of mutant embryos on day 10.5 of development (Meyer and Birchmeier, 1995; Kramer et al., 1996). In the myocardium, similar defects are observed in animals that lack erbB4, whereas the development of cranial ganglia is affected ...
PDF
... suggested as a model of action selection in the basal ganglia.27–30 In one version of these, called Actor/Critic models, it has been suggested29 that ventral striatal areas (the so called ‘Critic’) learn to evaluate situations or states of the world, by using a reward prediction error signal provide ...
... suggested as a model of action selection in the basal ganglia.27–30 In one version of these, called Actor/Critic models, it has been suggested29 that ventral striatal areas (the so called ‘Critic’) learn to evaluate situations or states of the world, by using a reward prediction error signal provide ...
- Wiley Online Library
... OXA-type enzymes are not as well inhibited by sulbactam as TEM-1 and other clinically used inhibitors. In general, b-lactamase inhibitors have negligible antimicrobial activity themselves, but restore antimicrobial activity to other b-lactams when used in combination. However, sulbactam is exception ...
... OXA-type enzymes are not as well inhibited by sulbactam as TEM-1 and other clinically used inhibitors. In general, b-lactamase inhibitors have negligible antimicrobial activity themselves, but restore antimicrobial activity to other b-lactams when used in combination. However, sulbactam is exception ...
Unauthorized Research on Cluster Headache
... the TV show House not once, but twice (Kaplow 2006; Dick 2007)! The first mention of therapeutic effect from a psychedelic on headache comes from Drs. D. Webster Prentiss and Francis P. Morgan, professors of medicine and pharmacology at Columbian University (now George Washington University), who be ...
... the TV show House not once, but twice (Kaplow 2006; Dick 2007)! The first mention of therapeutic effect from a psychedelic on headache comes from Drs. D. Webster Prentiss and Francis P. Morgan, professors of medicine and pharmacology at Columbian University (now George Washington University), who be ...
The Spinal Nerve
... Interneurons—Interpret, plan, coordinate signals in and out—20 billion Neuronal Pools Functional groups of interconnected neurons (interneurons) Each with limited input sources and output destinations May stimulate or depress parts of brain or spinal cord ...
... Interneurons—Interpret, plan, coordinate signals in and out—20 billion Neuronal Pools Functional groups of interconnected neurons (interneurons) Each with limited input sources and output destinations May stimulate or depress parts of brain or spinal cord ...
the human entorhinal cortex
... hippocampus. In addition, their largely non-overlapping distribution suggests that each neuron type modulates a different subset of topographically-organized entorhinal outputs. 1B) Based on the shape of the somata and primary dendritic trees, spiny neurons were divided into classical pyramidal, ste ...
... hippocampus. In addition, their largely non-overlapping distribution suggests that each neuron type modulates a different subset of topographically-organized entorhinal outputs. 1B) Based on the shape of the somata and primary dendritic trees, spiny neurons were divided into classical pyramidal, ste ...
Long-term lorazepam use in elderly psychiatric outpatients
... subjects) was associated with the magnitude of memory and psychomotor impairments following acute lorazepam administration, we modeled the outcome at 2.5 hours (i.e., time of peak effect) as a function of treatment, challenge dose and their interaction. We also explored whether the association betwe ...
... subjects) was associated with the magnitude of memory and psychomotor impairments following acute lorazepam administration, we modeled the outcome at 2.5 hours (i.e., time of peak effect) as a function of treatment, challenge dose and their interaction. We also explored whether the association betwe ...
1. Immediate 2. Delayed 3. Cumulative
... but it illustrates a very simple principle -- “If the dose of a drug is doubled then the duration of response will increase by one half-life.” The duration of response means the time that the drug effect is above a pre-defined critical value e.g. the time above 50% of Emax. With a low dose (blue lin ...
... but it illustrates a very simple principle -- “If the dose of a drug is doubled then the duration of response will increase by one half-life.” The duration of response means the time that the drug effect is above a pre-defined critical value e.g. the time above 50% of Emax. With a low dose (blue lin ...
In vivo pharmacokinetics and in vitro pharmacodynamics of
... amfenac is produced in the cornea.9 In the current study, nepafenac concentrations in the aqueous humor peaked at the first time point (30 minutes) and declined steadily thereafter. In contrast, amfenac concentration was low at 30 minutes and did not peak until 180 minutes. These observations are co ...
... amfenac is produced in the cornea.9 In the current study, nepafenac concentrations in the aqueous humor peaked at the first time point (30 minutes) and declined steadily thereafter. In contrast, amfenac concentration was low at 30 minutes and did not peak until 180 minutes. These observations are co ...
The novel endosomal membrane protein Ema interacts with the
... Kinchen et al., 2008; Liang et al., 2008). However, the molecular mechanisms by which the class C Vps–HOPS complex participates in such diverse functions remain largely unexplored. Endosomal trafficking of BMP receptors regulates developmental plasticity at the Drosophila neuromuscular junction (NMJ ...
... Kinchen et al., 2008; Liang et al., 2008). However, the molecular mechanisms by which the class C Vps–HOPS complex participates in such diverse functions remain largely unexplored. Endosomal trafficking of BMP receptors regulates developmental plasticity at the Drosophila neuromuscular junction (NMJ ...
INSOMNIA VS. SLEEP APNEA LEARNING OBJECTIVES List key
... 2417 subjects with insomnia > 60 years of age No other psychiatric/psychological disorders Treated with benzodiazepines, zopiclone, zolpidem, zapelon, ...
... 2417 subjects with insomnia > 60 years of age No other psychiatric/psychological disorders Treated with benzodiazepines, zopiclone, zolpidem, zapelon, ...