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2006 Practice Final Exam - Department of Chemistry | Oregon State
2006 Practice Final Exam - Department of Chemistry | Oregon State

... A student titrates 1.000 gram of KHP (potassium hydrogen phthalate MW=204.2 g/mol) to the equivalence point with 45.75 mL of NaOH (aq). The concentration of the NaOH solution is: (A) (B) (C) (D) (E) ...
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Nucleophilic acyl substitution



Nucleophilic acyl substitution describe a class of substitution reactions involving nucleophiles and acyl compounds. In this type of reaction, a nucleophile – such as an alcohol, amine, or enolate – displaces the leaving group of an acyl derivative – such as an acid halide, anhydride, or ester. The resulting product is a carbonyl-containing compound in which the nucleophile has taken the place of the leaving group present in the original acyl derivative. Because acyl derivatives react with a wide variety of nucleophiles, and because the product can depend on the particular type of acyl derivative and nucleophile involved, nucleophilic acyl substitution reactions can be used to synthesize a variety of different products.
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