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CH 6: Proteins and Amino Acids
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... – Order of the a.a. is determined by your DNA – The sequence of amino acids in each protein determines its unique shape and function. – For the protein to function the amino acids must be in the correct order and the chain must fold up properly ...
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... Amino acids degrading to oxaloacetate Aspartate and asparagine are metabolites that are  directly related to oxaloacetate through  transamination and amide formation. Therefore, degradation of asparagine and  aspartate yields oxaloacetate, which can be used  directly to gluconeogenesis   ...
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... The first stage of protein synthesis is amino acid activation, a process in which amino acids are attached to transfer RNA molecules. These RNA molecules are normally between 73 and 93 nucleotides in length and possess several characteristic structural features. The structure of tRNA becomes clearer ...
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No Slide Title - Docenti.unina

... Hydrophobicity is the most important characteristic of amino acids. It is the hydrophobic effect that drives proteins towards folding. Actually, it is all done by water. Water does not like hydrophobic surfaces. When a protein folds, exposed hydrophobic side chains get buried, and release water of i ...
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... finds the beginning of a protein recipe called the promotor - promotor = a series of nucleotides that indicate the start of a protein recipe The RNA polymerase opens the DNA molecule at the promotor ...
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... VI. Serine, Cysteine and Glycine Biosynthesis. Serine is synthesized from 3-phosphoglycerate. Serine is a precursor for both cysteine and glycine. The first step is the oxidation of 3-phosphoglycerate into 3-phosphohydroxypyruvate. The enzyme that catalyzes the oxidation is 3-phosphoglycerate dehydr ...
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Identification of a factor IX point mutation using SSCP analysis and
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... A molecular defect was localized to exon VI by single-strand conformation polymorphism (SSCP) analysis (2). To obtain sequence data the polymerase chain reaction (PCR, (3)) was used to symmetrically amplify a 250 bp fragment encompassing all of exon VI including both intron—exon splice junctions. Th ...
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Genetic code



The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.
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