NAGS - BMC Biochemistry
... glutamine, bicarbonate and ATP as substrates [53]. Nacetylglutamate (NAG), which is formed enzymatically by N-acetylglutamate synthase (NAGS; EC 2.3.1.1) from glutamate and acetyl coenzyme A (Figure 1), is an essential allosteric activator of CPSI, and deficiency of NAG results in a block in ureagen ...
... glutamine, bicarbonate and ATP as substrates [53]. Nacetylglutamate (NAG), which is formed enzymatically by N-acetylglutamate synthase (NAGS; EC 2.3.1.1) from glutamate and acetyl coenzyme A (Figure 1), is an essential allosteric activator of CPSI, and deficiency of NAG results in a block in ureagen ...
9. Wakil, S. J., Green, DE, Mii, S., and Mahler, HR (1954) Studies on
... enzymes that constitute the pathway for fatty acid synthesis in bacteria which offering additional weights into the construction of fatty acid chains in animals. Using the bacterial system, he helped elucidate the role of a protein as the coenzyme for fatty acid synthesis named the acyl carrier prot ...
... enzymes that constitute the pathway for fatty acid synthesis in bacteria which offering additional weights into the construction of fatty acid chains in animals. Using the bacterial system, he helped elucidate the role of a protein as the coenzyme for fatty acid synthesis named the acyl carrier prot ...
Characterization of an Immuno-dominant Variable Surface
... region of both actin and ferredoxin genes (Fig . 5), the only other genes of E. histolytica where sequence has been determined. The transcriptional start site of M17 was mapped to an adenine residue 17 by 5' of the start codon by primer extension sequence analysis using oligonucleotide SR09 (data no ...
... region of both actin and ferredoxin genes (Fig . 5), the only other genes of E. histolytica where sequence has been determined. The transcriptional start site of M17 was mapped to an adenine residue 17 by 5' of the start codon by primer extension sequence analysis using oligonucleotide SR09 (data no ...
Title Biotin Biosynthesis in Microorganisms (Commemoration Issue
... methionine to be most effective, and secondly that Na2SO3, Na2S, Na2SO4, homocysteine, SAM and methylmercaptan were also effective. They used 35S-methionine and detected the reaction products by radioautography. Radioactive biotin, biocytin and biocytin sulfoxide were formed. The authors74>also test ...
... methionine to be most effective, and secondly that Na2SO3, Na2S, Na2SO4, homocysteine, SAM and methylmercaptan were also effective. They used 35S-methionine and detected the reaction products by radioautography. Radioactive biotin, biocytin and biocytin sulfoxide were formed. The authors74>also test ...
No Slide Title
... – results in the activation of AMP deaminase that catalyzes the irreversible deamination of AMP to IMP (inosine monophosphate), a precursor of uric acid. – depletion of tissue ATP occurs through massive degradation to uric acid, and the impairment of regeneration by oxidative phosphorylation in the ...
... – results in the activation of AMP deaminase that catalyzes the irreversible deamination of AMP to IMP (inosine monophosphate), a precursor of uric acid. – depletion of tissue ATP occurs through massive degradation to uric acid, and the impairment of regeneration by oxidative phosphorylation in the ...
Rat sn-glycerol-3-phosphate acyltransferase - UNC
... are critical to glycerol-3-phosphate binding and catalysis in E. coli GPAT (Table 1) [21], we propose that these acyltransferases function using a similar catalytic mechanism. Through site-directed mutagenesis studies, we have shown that in E. coli GPAT, residues H306, D311, F351, I352, and P421 are ...
... are critical to glycerol-3-phosphate binding and catalysis in E. coli GPAT (Table 1) [21], we propose that these acyltransferases function using a similar catalytic mechanism. Through site-directed mutagenesis studies, we have shown that in E. coli GPAT, residues H306, D311, F351, I352, and P421 are ...
Ch23-Oxidation of Fatty Acids and Ketone Bodies
... Carnitine serves as the carrier that transports activated long chain fatty acyl groups across the inner mitochondrial membrane (Fig. 23.4). Carnitine acyl transferases are able to reversibly transfer an activated fatty acyl group from CoA to the hydroxyl group of carnitine to form an acylcarnitine e ...
... Carnitine serves as the carrier that transports activated long chain fatty acyl groups across the inner mitochondrial membrane (Fig. 23.4). Carnitine acyl transferases are able to reversibly transfer an activated fatty acyl group from CoA to the hydroxyl group of carnitine to form an acylcarnitine e ...
Substrate Specificity of Tonin from Rat Submaxillary Gland
... The Km values of tonin for (des-Aspl)-angiotensin I and angiotensin I are almost identical, whereas that of (desAsp',des-Arg')-angiotensin I is approximately doubled compared to the values observed with the latter two peptides. The Km values determined for angiotensin I and angiotensin I-converting ...
... The Km values of tonin for (des-Aspl)-angiotensin I and angiotensin I are almost identical, whereas that of (desAsp',des-Arg')-angiotensin I is approximately doubled compared to the values observed with the latter two peptides. The Km values determined for angiotensin I and angiotensin I-converting ...
evaluation of l-methionine bioavailability in nursery pigs
... Food Sciences. Appreciation is offered to Mr. Jim Monegue for his assistance and patience in the management of the experimental animals reported in this thesis; and to the farm crew, Mr. Billy Patton, Mr. Vern Graham, and Mr. Robert Elliot for their help in the feeding, weighing and bleeding of pigs ...
... Food Sciences. Appreciation is offered to Mr. Jim Monegue for his assistance and patience in the management of the experimental animals reported in this thesis; and to the farm crew, Mr. Billy Patton, Mr. Vern Graham, and Mr. Robert Elliot for their help in the feeding, weighing and bleeding of pigs ...
The Mechanism of Enterohepatic Circulation in the Formation of
... epimerization also can be achieved in cocultures of intestinal bacteria, one possessing 7a-HSDH and the other 7b-HSDH (Hirano and Masuda 1981; MacDonald et al. 1982). The extent of the reversible oxidation and reduction of bile acid hydroxy groups by HSDH depends in part on the redox potential of th ...
... epimerization also can be achieved in cocultures of intestinal bacteria, one possessing 7a-HSDH and the other 7b-HSDH (Hirano and Masuda 1981; MacDonald et al. 1982). The extent of the reversible oxidation and reduction of bile acid hydroxy groups by HSDH depends in part on the redox potential of th ...
CO2 Capture from Flue gas using Amino acid salt
... such as mono-ethanolamine (MEA), but their use implies economic disadvantages and environmental complications. Amino acid salt solutions have emerged as an alternative to the alkanolamines, partly because they are naturally occurring substances, and partly because they have desirable properties, suc ...
... such as mono-ethanolamine (MEA), but their use implies economic disadvantages and environmental complications. Amino acid salt solutions have emerged as an alternative to the alkanolamines, partly because they are naturally occurring substances, and partly because they have desirable properties, suc ...
Some pyridoxal analogs and their transamination with amino acids
... the dissociation constants of these acidic and basic groups be important factors in effecting the efficiency of the catalysis? If so, then how does the stereochemical arrangement of these groups in relation to the coenzyme-substrate complex account for the catalysis? Furthermore, how important are d ...
... the dissociation constants of these acidic and basic groups be important factors in effecting the efficiency of the catalysis? If so, then how does the stereochemical arrangement of these groups in relation to the coenzyme-substrate complex account for the catalysis? Furthermore, how important are d ...
Flux analysis in central carbon metabolism in plants
... enumeration of feasible bondomers in a metabolic network reduced the number of bondomer balances 3-fold. This resulted in a simplified system that offers the advantages of faster computation, and easier flux identifiability analysis. Furthermore, a computational technique called Boolean function map ...
... enumeration of feasible bondomers in a metabolic network reduced the number of bondomer balances 3-fold. This resulted in a simplified system that offers the advantages of faster computation, and easier flux identifiability analysis. Furthermore, a computational technique called Boolean function map ...
post- translational modifications
... We are pleased to present a selection of our building blocks for the synthesis of PTM peptides and proteins. Post-translational modifications (PTMs) enable the cell to change the properties and activities of proteins after expression. Most of the PTMs are catalyzed by specialized enzymes. Practicall ...
... We are pleased to present a selection of our building blocks for the synthesis of PTM peptides and proteins. Post-translational modifications (PTMs) enable the cell to change the properties and activities of proteins after expression. Most of the PTMs are catalyzed by specialized enzymes. Practicall ...
Isolation and Characterization of Protease Inhibitors from Animal
... inhibitors with notable sequence resemblance to known serine proteases have been separated (Yanes et al. 2005). The majority of these H. medicinalis serine proteases are found in different leech trypsin inhibitor families. However, other inhibitors are similar to other families. For instance, the 3, ...
... inhibitors with notable sequence resemblance to known serine proteases have been separated (Yanes et al. 2005). The majority of these H. medicinalis serine proteases are found in different leech trypsin inhibitor families. However, other inhibitors are similar to other families. For instance, the 3, ...
- Surrey Research Insight Open Access
... used in a clinical environment to treat diseases and disorders characterised by muscle hypertension or spasm. However, previous research has mostly focused on the biochemical mode of action of the toxin and the disease it manifests. In order to increase our understanding of the process further, this ...
... used in a clinical environment to treat diseases and disorders characterised by muscle hypertension or spasm. However, previous research has mostly focused on the biochemical mode of action of the toxin and the disease it manifests. In order to increase our understanding of the process further, this ...
Saccharomyces species in the Production of Beer
... in Germany for the production production of beer were water, barley, and hops. The principal purpose of the law was to prevent of beer were water, barley, and hops. The principal purpose of the law was to prevent price competition price competition with bakers for wheat and rye and to ensure the av ...
... in Germany for the production production of beer were water, barley, and hops. The principal purpose of the law was to prevent of beer were water, barley, and hops. The principal purpose of the law was to prevent price competition price competition with bakers for wheat and rye and to ensure the av ...
Microsoft Word
... The interaction of mAb 15 (Figure 3A) with the single mutants E604A and D630N was drastically reduced (about 80% and 100%, respectively) and, to a lesser extent, with D620R (about 50%). In the case of multiple mutants, a decrease in mAb 15 binding was also observed which ranged from about 60% for K6 ...
... The interaction of mAb 15 (Figure 3A) with the single mutants E604A and D630N was drastically reduced (about 80% and 100%, respectively) and, to a lesser extent, with D620R (about 50%). In the case of multiple mutants, a decrease in mAb 15 binding was also observed which ranged from about 60% for K6 ...
Data mining for important amino acid residues in multiple sequence
... Enzymes are highly efficient bio-catalysts interesting for industries and medicine. Therefore, a goal of utmost importance in biochemical research is to understand how an enzyme catalyzes a chemical reaction. Here, the computational identification of functionally or structurally important residue po ...
... Enzymes are highly efficient bio-catalysts interesting for industries and medicine. Therefore, a goal of utmost importance in biochemical research is to understand how an enzyme catalyzes a chemical reaction. Here, the computational identification of functionally or structurally important residue po ...
An N-terminally truncated envelope protein encoded
... pol gene, the complete env gene, and U3 and R regions of the 3′LTR (Figure 1A). The primary sequence of the Env protein encoded by Xq22.3 HERV-W env is shown in Figure 1B. To analyze the coding capacity of Xq22.3 HERV-W env, we PCR-amplified from human genomic DNA a 1862 bp sequence beginning at the ...
... pol gene, the complete env gene, and U3 and R regions of the 3′LTR (Figure 1A). The primary sequence of the Env protein encoded by Xq22.3 HERV-W env is shown in Figure 1B. To analyze the coding capacity of Xq22.3 HERV-W env, we PCR-amplified from human genomic DNA a 1862 bp sequence beginning at the ...
Pseudomon-1 motif
... gabT motif..................................................................................................................... 14 Gamma-cis-1 motif ....................................................................................................... 15 GUCCY hairpin motif........................ ...
... gabT motif..................................................................................................................... 14 Gamma-cis-1 motif ....................................................................................................... 15 GUCCY hairpin motif........................ ...
Glutamine and the bowel
... → intestinal glutamine metabolism: 1. Contribute a nutritionally important portion of intestinal energy generation. 2. As precursor:synthesis of ornithine, cotrulline, proline and arginine. ...
... → intestinal glutamine metabolism: 1. Contribute a nutritionally important portion of intestinal energy generation. 2. As precursor:synthesis of ornithine, cotrulline, proline and arginine. ...
Bacterial ribosome requires multiple L12 dimers for efficient initiation
... interaction in L12 dimer, had no functional relevance and was contradicted by an NMR structure where both the hinges were seen in fully extended form (9,11). Thus it is now universally accepted that the L12 dimer is ‘antiparallel’ where NTDs of two L12 molecules form a four-helix bundle dimer occupy ...
... interaction in L12 dimer, had no functional relevance and was contradicted by an NMR structure where both the hinges were seen in fully extended form (9,11). Thus it is now universally accepted that the L12 dimer is ‘antiparallel’ where NTDs of two L12 molecules form a four-helix bundle dimer occupy ...
Abstract
... and formyl-THF. These folate coenzymes play essential roles in the synthesis of nucleic acids and amino acid metabolism. Because folates also contain variable numbers of glutamate residues, cells contain a truly bewildering array of mono- and poly-glutamated folate derivatives. Formyl-THF-Glu3 is th ...
... and formyl-THF. These folate coenzymes play essential roles in the synthesis of nucleic acids and amino acid metabolism. Because folates also contain variable numbers of glutamate residues, cells contain a truly bewildering array of mono- and poly-glutamated folate derivatives. Formyl-THF-Glu3 is th ...
5 The structure and function of membrane proteins
... powerful, desktop computers with performance equivalent to the previous generation of supercomputers. Many experimental techniques relied on the codevelopment of computer hardware but software has also played a vital role in protein biochemistry. We can now search databases comparing proteins at the ...
... powerful, desktop computers with performance equivalent to the previous generation of supercomputers. Many experimental techniques relied on the codevelopment of computer hardware but software has also played a vital role in protein biochemistry. We can now search databases comparing proteins at the ...
Genetic code
The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.