Technical Brief
... regarding the origin of the disease. 6 It noted simply that it is frequently associated with a monotonous maize-based diet and concludes with the following statement: “Breast milk is probably deficient in some factors, which are at present uncertain. As maize is the only source of supplementary food ...
... regarding the origin of the disease. 6 It noted simply that it is frequently associated with a monotonous maize-based diet and concludes with the following statement: “Breast milk is probably deficient in some factors, which are at present uncertain. As maize is the only source of supplementary food ...
The Protein Cevalently Linked to the 5'... of Poliovirus RNA by Victor Robert Ambros
... D. Kinetics of removal of VPg from poliovirus RNA in Hela cell extracts........................................ 84 E. Release of VPg from polio RNA in other cell extracts..... 88 F. Glycerol gradient sedimentation of Hela unlinking activity.................................................. 91 G. Mag ...
... D. Kinetics of removal of VPg from poliovirus RNA in Hela cell extracts........................................ 84 E. Release of VPg from polio RNA in other cell extracts..... 88 F. Glycerol gradient sedimentation of Hela unlinking activity.................................................. 91 G. Mag ...
Organic Molecules
... • Phospholipids have polar (charged) & nonpolar (not charged) ends. The phosphate end is HYDROPHILIC. The fatty acid end is HYDROPHOBIC. • The unique structure (polar & nonpolar) contributes to the function of these molecules in the cell. ...
... • Phospholipids have polar (charged) & nonpolar (not charged) ends. The phosphate end is HYDROPHILIC. The fatty acid end is HYDROPHOBIC. • The unique structure (polar & nonpolar) contributes to the function of these molecules in the cell. ...
The Maillard Reaction
... I Initial stage: products colourless, without absorption in the ultraviolet (about ...
... I Initial stage: products colourless, without absorption in the ultraviolet (about ...
universidade estadual de maringá metabolic alterations caused by
... Usnic acid is a naturally occurring dibenzofuran derivative found in several lichen species. The compound has been marketed as an ingredient of food supplements for weight reduction. There is evidence that the compound acts as an uncoupler of mitochondrial oxidative phosphorylation and it is also cl ...
... Usnic acid is a naturally occurring dibenzofuran derivative found in several lichen species. The compound has been marketed as an ingredient of food supplements for weight reduction. There is evidence that the compound acts as an uncoupler of mitochondrial oxidative phosphorylation and it is also cl ...
Biochemical studies of enzymes in insect cuticle hardening
... and the pathway of insect taurine biosynthesis. Cysteine was found to be an inactivator of several PLP-dependent decarboxylases, such as ADC, glutamate decarboxylase (GAD) and CSADC. This study helps to understand symptoms associated with the abnormal cysteine concentrations in several neurodegener ...
... and the pathway of insect taurine biosynthesis. Cysteine was found to be an inactivator of several PLP-dependent decarboxylases, such as ADC, glutamate decarboxylase (GAD) and CSADC. This study helps to understand symptoms associated with the abnormal cysteine concentrations in several neurodegener ...
The causes of epistasis - Proceedings of the Royal Society B
... networks, and the interactions inherent in these relationships play a key role in determining epistasis. Szathmáry [65] modelled a linear pathway to study this relationship, assuming that mutations had additive effects on enzyme activity and that activity was near the optimum. Four regimes were con ...
... networks, and the interactions inherent in these relationships play a key role in determining epistasis. Szathmáry [65] modelled a linear pathway to study this relationship, assuming that mutations had additive effects on enzyme activity and that activity was near the optimum. Four regimes were con ...
The causes of epistasis - Proceedings of the Royal Society B
... networks, and the interactions inherent in these relationships play a key role in determining epistasis. Szathmáry [65] modelled a linear pathway to study this relationship, assuming that mutations had additive effects on enzyme activity and that activity was near the optimum. Four regimes were con ...
... networks, and the interactions inherent in these relationships play a key role in determining epistasis. Szathmáry [65] modelled a linear pathway to study this relationship, assuming that mutations had additive effects on enzyme activity and that activity was near the optimum. Four regimes were con ...
Unusual ADP-forming acetyl-coenzyme A synthetases from the
... In the sequenced genome of P. aerophilum, the genes putatively encoding the a and b subunits of ACD were identified by BLAST search using the amino acid sequences of the a and b subunits of the ACD isoenzyme I from P. furiosus. The ORFs PAE3250 and PAE3249, designated acdA and acdB, respectively, wer ...
... In the sequenced genome of P. aerophilum, the genes putatively encoding the a and b subunits of ACD were identified by BLAST search using the amino acid sequences of the a and b subunits of the ACD isoenzyme I from P. furiosus. The ORFs PAE3250 and PAE3249, designated acdA and acdB, respectively, wer ...
The Major Component of the Paraflagellar Rod of Trypanosoma
... similarity to the intermediate filament proteins (solubility properties, amino acid composition, and high degree of helicity), the PFR protein does not belong in this class of cytoskeletal proteins. The PFR protein is coded for by two tandemly linked genes of identical nucleotide sequence. Both gene ...
... similarity to the intermediate filament proteins (solubility properties, amino acid composition, and high degree of helicity), the PFR protein does not belong in this class of cytoskeletal proteins. The PFR protein is coded for by two tandemly linked genes of identical nucleotide sequence. Both gene ...
Solid Phase Synthesis on SASRIN
... Peptide fragments containing Tyr(tBu), Lys(Boc), or His(Trt) can be safely obtained only under these conditions when the cleavage proceeds rapidly (see Table 1). Thus, SASRIN (2-methoxy-4-alkoxybenzyl alcohol resin) is sufficiently acid-labile so that Tyr(tBu), Lys(Boc), and His(Trt) are left intact ...
... Peptide fragments containing Tyr(tBu), Lys(Boc), or His(Trt) can be safely obtained only under these conditions when the cleavage proceeds rapidly (see Table 1). Thus, SASRIN (2-methoxy-4-alkoxybenzyl alcohol resin) is sufficiently acid-labile so that Tyr(tBu), Lys(Boc), and His(Trt) are left intact ...
Chapter 4: Cellular Metabolism
... (Outcome 4.9, 4.10) 1. Energy is ______________________________________ . (Outcome 4.9, 4.10) 2. Six forms of energy are ___________________________ _________________________________________________________________ . (Outcome 4.9, 4.10) 3. Energy can be changed from ______________________ . (Outcome ...
... (Outcome 4.9, 4.10) 1. Energy is ______________________________________ . (Outcome 4.9, 4.10) 2. Six forms of energy are ___________________________ _________________________________________________________________ . (Outcome 4.9, 4.10) 3. Energy can be changed from ______________________ . (Outcome ...
REDESIGN OF CARNITINE ACETYLTRANSFERASE SPECIFICITY BY PROTEIN ENGINEERING UNIVERSIDAD DE BARCELONA
... A novel compound, the fatty acid synthase (FAS) inhibitor C75, has been proposed to pharmacologically regulate CPT I activity (Price, 2001). Structurally, C75 is a cell-permeable α-methylene-γ-butyrolactone designed to be less reactive and potentially safer than cerulenin, a natural product obtained ...
... A novel compound, the fatty acid synthase (FAS) inhibitor C75, has been proposed to pharmacologically regulate CPT I activity (Price, 2001). Structurally, C75 is a cell-permeable α-methylene-γ-butyrolactone designed to be less reactive and potentially safer than cerulenin, a natural product obtained ...
animal nutrition - e
... Adams University College were invited to join the team. These new authors contribute a broad knowledge of animal nutrition and will ensure that the book can go to further editions. In this edition we have attempted to address comments and suggestions made by reviewers in order to improve the book. T ...
... Adams University College were invited to join the team. These new authors contribute a broad knowledge of animal nutrition and will ensure that the book can go to further editions. In this edition we have attempted to address comments and suggestions made by reviewers in order to improve the book. T ...
Nucleic acid vaccines against rickettsial diseases and methods of use
... ettsial diseases: certain unsettled problems in their historical perspective,” In Rickettsia and Rickettsial Diseases, W. Burgdorfer and R. Anacker, eds., Academic Press, NeW ...
... ettsial diseases: certain unsettled problems in their historical perspective,” In Rickettsia and Rickettsial Diseases, W. Burgdorfer and R. Anacker, eds., Academic Press, NeW ...
Purification of Arrestin from Bovine Retinas
... The amino acid sequence of arrestin was determined first for bovine arrestin (7), and the sequence has now been determined for an additional five species. Arrestin contains a relatively high proportion of nonpolar amino acids (55%) that are assembled in a /3-sheet conformation (7, 8). However, very ...
... The amino acid sequence of arrestin was determined first for bovine arrestin (7), and the sequence has now been determined for an additional five species. Arrestin contains a relatively high proportion of nonpolar amino acids (55%) that are assembled in a /3-sheet conformation (7, 8). However, very ...
Regulation of Phenylalanine and Tyrosine
... hyperbolic with K , values of 0.31 r n M for chorismate and 0.015 mM for prephenate, respectively. The substrate saturation curve of the complexed prephenate dehydratase I was sigmoid; a Km value of 0-18 mM was calculated for prephenate. Chorismate mutase, prephenate dehydratase and prephenate dehyd ...
... hyperbolic with K , values of 0.31 r n M for chorismate and 0.015 mM for prephenate, respectively. The substrate saturation curve of the complexed prephenate dehydratase I was sigmoid; a Km value of 0-18 mM was calculated for prephenate. Chorismate mutase, prephenate dehydratase and prephenate dehyd ...
Phosphorylation of the F1Fo ATP Synthase Я Subunit
... system of Saccharomyces cerevisiae was chosen so that each phosphorylation could be studied independently and in the context of a complete knock out of the endogenous protein. The amino acid residues were mutated to nonphosphorylatable (alanine) or phosphomimetic (aspartic acid and glutamic acid) re ...
... system of Saccharomyces cerevisiae was chosen so that each phosphorylation could be studied independently and in the context of a complete knock out of the endogenous protein. The amino acid residues were mutated to nonphosphorylatable (alanine) or phosphomimetic (aspartic acid and glutamic acid) re ...
Cholesterol Homeostasis - Sigma
... to the Golgi where SREBP is cleaved and a portion of it can now move into the nucleus, where it interacts with SREs to promote gene expression. When oxysterol levels are high the SCAP/SREBP complex remains in the ER preventing cleaved SREBP from promoting gene expression. SREBPs serve to regulate al ...
... to the Golgi where SREBP is cleaved and a portion of it can now move into the nucleus, where it interacts with SREs to promote gene expression. When oxysterol levels are high the SCAP/SREBP complex remains in the ER preventing cleaved SREBP from promoting gene expression. SREBPs serve to regulate al ...
The Unusual Binding Properties of the Third Distinct Teleost
... duplication of ER early in the teleost lineage after the divergence of ray- and lobe-finned fishes. These three subtypes were subsequently identified in zebrafish (19). The acER ortholog in zebrafish is now designated ERb or ESR2b (previously ER1) to comply with official zebrafish nomenclature r ...
... duplication of ER early in the teleost lineage after the divergence of ray- and lobe-finned fishes. These three subtypes were subsequently identified in zebrafish (19). The acER ortholog in zebrafish is now designated ERb or ESR2b (previously ER1) to comply with official zebrafish nomenclature r ...
Endonucleolytic processing of CCAless tRNA precursors by RNase
... endoribonuclease, known as RNase Z (or 3¢ tRNase), in many eukaryotic and archaeal systems. RNase Z cleaves tRNA precursors 3¢ to the discriminator base. Here we show that this activity, previously unsuspected in bacteria, is encoded by the yqjK gene of Bacillus subtilis. Decreased yqjK expression l ...
... endoribonuclease, known as RNase Z (or 3¢ tRNase), in many eukaryotic and archaeal systems. RNase Z cleaves tRNA precursors 3¢ to the discriminator base. Here we show that this activity, previously unsuspected in bacteria, is encoded by the yqjK gene of Bacillus subtilis. Decreased yqjK expression l ...
6.
... mistakes would not represent functional, regulated alternative splicing. What portion of the observed splice variants represents functional alternative splicing? We employed a comparative genomics approach to address this question, by compiling a dataset of exon-skipping events (cassette exons) that ...
... mistakes would not represent functional, regulated alternative splicing. What portion of the observed splice variants represents functional alternative splicing? We employed a comparative genomics approach to address this question, by compiling a dataset of exon-skipping events (cassette exons) that ...
Locked Nucleic Acid (LNA™)
... LNA™ has been proven to be a powerful tool in many molecular biological applications in which standard DNA oligonucleotides or RNA riboprobes do not show sufficient affinity or specificity. LNA™ can be used to overcome the difficulties of studying very short sequences and has greatly improved, and i ...
... LNA™ has been proven to be a powerful tool in many molecular biological applications in which standard DNA oligonucleotides or RNA riboprobes do not show sufficient affinity or specificity. LNA™ can be used to overcome the difficulties of studying very short sequences and has greatly improved, and i ...
Developement of strategies for the isotopic labeling of methyl
... permits the suppression of spurious correlations, especially harmful for structural studies based on detection/analysis of nOes. To make an efficient use of the obtained high quality NMR spectra using this protocol, assignment of the methyl groups signals is mandatory. Two strategies were then propo ...
... permits the suppression of spurious correlations, especially harmful for structural studies based on detection/analysis of nOes. To make an efficient use of the obtained high quality NMR spectra using this protocol, assignment of the methyl groups signals is mandatory. Two strategies were then propo ...
Mechanistic studies on the diazo transfer reaction
... As reported in the literature the diazo transfer reaction can be used to modify enzymes, antibiotics, and proteins to study their functions or to modify their activity. But in these cases, the Cu(II) catalyst is avoided lest it have any adverse effect on the structure or biological function of the p ...
... As reported in the literature the diazo transfer reaction can be used to modify enzymes, antibiotics, and proteins to study their functions or to modify their activity. But in these cases, the Cu(II) catalyst is avoided lest it have any adverse effect on the structure or biological function of the p ...
Genetic code
The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.