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Sugar Metabolism in Yeasts: an Overview of Aerobic and Anaerobic
Sugar Metabolism in Yeasts: an Overview of Aerobic and Anaerobic

... polyols, alcohols, organic acids and amino acids) that can support their growth but preferentially they metabolize sugars. The information related to the metabolism of different carbon sources is huge, the most widely studied being sugars such as hexoses (glucose, fructose, galactose or mannose) and ...
Full-Text PDF
Full-Text PDF

... generation of metabolic energy and hence in the survival of most cells. The TCA cycle intermediates fuel this mitochondrial metabolism. However, mitochondria also are the site at which a considerable amount of highly reactive oxygen radicals (superoxide, hydrogen peroxide, and hydroxyl radical) is g ...
Combined therapy with PPARα agonist and l
Combined therapy with PPARα agonist and l

... Objective: Peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors that belong to the nuclear hormone receptor superfamily and are key regulators of fatty acid oxidation (FAO) in the heart. Systemic carnitine deficiency (SCD) causes disorders of FAO and induces ...
Calculation of substrate oxidation rates in vivo
Calculation of substrate oxidation rates in vivo

... Equation 8 shows that for each 2 mol (1,723 g) of fat circumstances, i.e., when there is accumulation within, or excretion from, the body of an intermediate or end produced, 27 mol (4,865 g) of glucose and 6 mol (134 liters) of O2 are used and 52 mol (1,165 liters) of CO:! product other than CO2 or ...
Activation of Peroxisome Proliferator-Activated Receptors
Activation of Peroxisome Proliferator-Activated Receptors

... DHEA is distinguished from other steroids by its chemoprotective properties (8,9). DHEA can also stimulate a dramatic Introduction increase in both the size and number of Trichloroethylene (TCE) is a widely used associated with a number of several adverse peroxisomes in liver when given to rodents a ...
Planta
Planta

... citrate begins with the condensation of the two-carbon acetyl-CoA and the four-carbon oxaloacetate to yield the six-carbon citrate. The reaction is catalyzed by citrate synthase in the mitochondria, as part of the TCA cycle (Sadka et al. 2001). Regulation of the isomerization of citrate to isocitrat ...
Chapter 29 The Organic Chemistry of Metabolic Pathways
Chapter 29 The Organic Chemistry of Metabolic Pathways

... C-OH with NADPH, an analogue of NADH having an additional phosphate  Dehydration of the -hydroxy thioester yields transcrotonyl ACP  The C=C of crotonyl ACP is reduced with NADPH to yield butyryl ACP  The reaction is repeated until the appropriate length ...
Chapter 29 The Organic Chemistry of Metabolic Pathways
Chapter 29 The Organic Chemistry of Metabolic Pathways

... C-OH with NADPH, an analogue of NADH having an additional phosphate  Dehydration of the -hydroxy thioester yields transcrotonyl ACP  The C=C of crotonyl ACP is reduced with NADPH to yield butyryl ACP  The reaction is repeated until the appropriate length ...
Redox balances in the metabolism of sugars by yeasts
Redox balances in the metabolism of sugars by yeasts

... cytoplasm. The fate of NADH in intermediary metabolism is much more complicated than that of NADPH. NADH is generated both in the cytosol (during glycolysis) and in the mitochondria (via TCA-cycle enzymes) (Fig. 2). In mammalian cells, various shuttle mechanisms are involved in the transport of redu ...
Redox balances in the metabolism of sugars by yeasts
Redox balances in the metabolism of sugars by yeasts

... cytoplasm. The fate of NADH in intermediary metabolism is much more complicated than that of NADPH. NADH is generated both in the cytosol (during glycolysis) and in the mitochondria (via TCA-cycle enzymes) (Fig. 2). In mammalian cells, various shuttle mechanisms are involved in the transport of redu ...
Quantitative flux analysis reveals folate
Quantitative flux analysis reveals folate

... the medium (Extended Data Fig. 8). As has been observed previously both in vitro17,18 and in tumour models19, serine depletion impaired cell growth (Extended Data Fig. 8b). Consistent with one important downstream product of serine being NADPH, its removal decreased NADPH/ NADP1 (Extended Data Fig. ...
PDF - Geoff McFadden`s Lab
PDF - Geoff McFadden`s Lab

... FNR transfers these electrons to NADP+, thereby creating reduced NADPH, which can be used either to generate ATP or as a cofactor in anabolic reactions. In darkness the reverse can occur, and NADPH is reoxidised by FNR to produce reduced ferredoxin37, which is essential for the activity of several f ...
Production of lactic acid using a new homofermentative
Production of lactic acid using a new homofermentative

... preferred component of many food and industrial applications that is currently produced via biological fermentation utilizing lactic acid bacteria or fungi such as Rhizopus. Some recombinant yeast strains have also been used to produce lactic acid from various carbon feedstocks (Porro et al., 2008). ...
The Proton-Motive Force Overview Compartmentalization
The Proton-Motive Force Overview Compartmentalization

... • Stalk causes ATP synthase to  have three different  conformations: open, loose,  tight • In “tight” conformation,  energy has been used to cause  an energy conformation that  favors ATP formation ...
Preview Sample 1 - Test Bank, Manual Solution, Solution Manual
Preview Sample 1 - Test Bank, Manual Solution, Solution Manual

... Learning Outcome: 02.05.02 Compare and contrast the structures and functions of the four classes of biological molecules. Section: 02.05 Topic: Chemistry ...
Livestock Nutrition
Livestock Nutrition

... Nutrients in the water soluble form, are primarily carried by the blood in the animals body from where they are absorbed to where they are utilized. Nutrients are used for maintenance, oxidation provides hear for body temperature and movement. Nutrients are also used fro growth and fattening, fetal ...
Insulina - Gilberto De Nucci
Insulina - Gilberto De Nucci

... hypoglycemic events noted per patient were reduced by 46.4% (p = 0.003) and occurred significantly less often during nocturnal periods (-63.2%, p = 0.002). Following the adjustment, the mean daily insulin requirement was reduced by 28.05% (from 0.82 to 0.59 IU/kg) and the new proportion of 40% as ba ...
Interactions between carbohydrate and lipid metabolism in
Interactions between carbohydrate and lipid metabolism in

... compartment. Glucose can enter the blood via two routes, i.e., dietary glucose derived from the intestine and glucose production by the liver and the kidney. During fasting, the organism will solely depend on the production of glucose, mainly by the liver. Glucose can be produced directly through gl ...
campbell ch#3 only
campbell ch#3 only

... that pKa values are not normally listed for these side chains.) In cysteine, the polar side chain consists of a thiol group (—SH), which can react with other cysteine thiol groups to form disulfide (—S—S—) bridges in proteins in an oxidation reaction (Section 1.9). The thiol group can also lose a pr ...
Accumulation of Carotenoids and Metabolic Profiling in Different
Accumulation of Carotenoids and Metabolic Profiling in Different

... species. Positive relationships were apparent between carbon-rich metabolites, including those of the TCA cycle and sugar metabolism, and carotenoids. Keywords: Tagetes; marigold; carotenoid; metabolic profiling; GC-TOFMS ...
Livestock Nutrition
Livestock Nutrition

... Nutrients in the water soluble form, are primarily carried by the blood in the animals body from where they are absorbed to where they are utilized. Nutrients are used for maintenance, oxidation provides hear for body temperature and movement. Nutrients are also used fro growth and fattening, fetal ...
Interactions between carbohydrate and lipid metabolism in
Interactions between carbohydrate and lipid metabolism in

... compartment. Glucose can enter the blood via two routes, i.e., dietary glucose derived from the intestine and glucose production by the liver and the kidney. During fasting, the organism will solely depend on the production of glucose, mainly by the liver. Glucose can be produced directly through gl ...
Exogenous glutamine increases lipid accumulation in
Exogenous glutamine increases lipid accumulation in

... to 0.8% to ensure that the seed surface was in good contact with the medium. Sucrose concentration was set as 85 mM to support growth and to establish an optimum rate under which cultured seeds grow well in vitro. Usually, the well-developed capsule is trilocular containing one large mottled seed pe ...
PROPERTIES OF CARBOXYLIC ACIDS
PROPERTIES OF CARBOXYLIC ACIDS

... organic chemistry refers to the chemistry of millions of carbon compounds. Theory of chemical structure of organic compounds was formulated by Butlerov A.M. in 1861. The importance of this theory for organic chemistry is like the importance of Mendeleev’s Periodic Table for inorganic chemistry. This ...
novel aspects of carnitine function and metabolism
novel aspects of carnitine function and metabolism

... and branched-chain amino acid (BCAA) oxidation disorders; 2) shed light on how acylcarnitine intermediates cross the outer mitochondrial membrane; 3) clarify the contribution of peroxisomes to the oxidation of medium-chain fatty acids when the carnitine shuttle is impaired, and 4) give a new insight ...
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Fatty acid metabolism

Fatty acids are a family of molecules classified within the lipid macronutrient class. One role of fatty acids within animal metabolism is energy production in the form of adenosine triphosphate (ATP) synthesis. When compared to other macronutrient classes (carbohydrates and protein), fatty acids yield the most ATP on an energy per gram basis by a pathway called β-oxidation. In addition, fatty acids are important for energy storage, phospholipid membrane formation, and signaling pathways. Fatty acid metabolism consists of catabolic processes that generate energy and primary metabolites from fatty acids, and anabolic processes that create biologically important molecules from fatty acids and other dietary sources.
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