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First line of defense
First line of defense

... - may be attached to cells or free floating - 10 billion different ones; each one binding to a specific antigen ...
THE PEARLS OF WISDOM - OSW
THE PEARLS OF WISDOM - OSW

... Myeloid progenitor cells develop into cells that respond early and nonspecifically to infection Lymphoid progenitor cells develop into lymphocytes ...
The Immune System 2
The Immune System 2

... The Immune System 2 ...
ch 40.2 notes - 4J Blog Server
ch 40.2 notes - 4J Blog Server

... Like security guard – deals with specific invaders  Antigen: subst. that triggers specific immune response ...
T-cell development in the thymus
T-cell development in the thymus

... positive selection, in the cortex. DP cells interact with self-antigens in the context of major histocompatabilty complex (MHC) class I or class II molecules. Those cells that engage antigen/MHC with an appropriate affinity survive, whereas those cells that interact with a weaker affinity die by apo ...
Immunity revision sheets
Immunity revision sheets

T-cell development in thymus
T-cell development in thymus

... positive selection, in the cortex. DP cells interact with self-antigens in the context of major histocompatabilty complex (MHC) class I or class II molecules. Those cells that engage antigen/MHC with an appropriate affinity survive, whereas those cells that interact with a weaker affinity die by apo ...
PHA 321 - Biosciences II
PHA 321 - Biosciences II

Study guid Ch 15
Study guid Ch 15

... What are B cells and what are their B cell receptors? What happens when a T cell activates a B cell? What is an antibody? Are they specific or general? Where are T and B cells generally found? How do they circulate around the body? How do DCs and macrophages get to the lymph nodes? Why is it importa ...
T Cell Development and Selection, Part I
T Cell Development and Selection, Part I

... 9) Influence of the cytokine Il-7. Phenotype of Il-7R chain knockout-diminished numbers of thymocytes, and genetic interaction with pT knockout. Il-7 is necessary for survival and proliferation of early T cells. ...
Defense Systems
Defense Systems

...  memory cells lie dormant until the next attack 3. Antigens are particles which can stimulate receptors on lymphocytes  only part of the foreign invader is antigenic 4. Antibodies are proteins produced by lymphocytes  light chain binds antigen  heavy chain binds to “destructive” processes in bod ...
Life Processes
Life Processes

Imunitní mechanismy
Imunitní mechanismy

... RELEASED FROM NECROTIC CELLS) ...
LEUKOPOIESIS LEARNING OBJECTIVES • To classify the different
LEUKOPOIESIS LEARNING OBJECTIVES • To classify the different

... They may migrate to other organs for further differentiation Leukopoiesis  Is hormonally stimulated by two families of cytokines (hematopoietic factors) – interleukins and colony-stimulating factors (CSFs)  Interleukins are numbered (e.g., IL-1, IL-2), whereas CSFs are named for the WBCs they stim ...
7-Organ
7-Organ

... Sites of lymphocyte activation and differentiation Spleen Lymph nodes Epithelial cell – associated lymphoid tissues Skin-associated lymphoid tissue (SALT) Mucosa-associated lymphoid tissue (MALT) Gut-associated lymphoid tissue (GALT) Bronchial tract-associated lymphoid tissue (BALT) ...
Chapter 1
Chapter 1

... whooping cough, tetanus, polio, and diptheria are extremely rare or nonexistent  This is due to vaccines!  Prevent death, paralysis, deafness, blindness, mental ...
Biology I 10/18/12
Biology I 10/18/12

... 7.1 Life is Cellular Cells are the basic structural and functional units of life.  They differ in structure and complexity ...
Lymphatic System
Lymphatic System

Unit #11: Animal Anatomy and Physiology- Immune
Unit #11: Animal Anatomy and Physiology- Immune

... 3. What are the non-specific defenses (1st line of defense) used in the immune system? ...
T cell
T cell

... Sites of lymphocyte activation and differentiation Spleen Lymph nodes Epithelial cell – associated lymphoid tissues Skin-associated lymphoid tissue (SALT) Mucosa-associated lymphoid tissue (MALT) Gut-associated lymphoid tissue (GALT) Bronchial tract-associated lymphoid tissue (BALT) ...
Describe how white blood cells defend the body against infection
Describe how white blood cells defend the body against infection

... - Eosinophils circulate in blood for 3-8 hours, then enter tissues, primarily epithelial, where they stay for 8-12 days. They are also phagocytic and are important for parasitic diseases - Basophils present in small numbers in blood, mostly in tissues as mast cell with binding sites for IgE → releas ...
lymphatic system - andoverhighanatomy
lymphatic system - andoverhighanatomy

Immunity - Honors
Immunity - Honors

... suppressor T cell ...
Kuby Immunology 6/e - Dr. Jennifer Capers, PhD
Kuby Immunology 6/e - Dr. Jennifer Capers, PhD

... CD4+ and CD8+ cells leave thymus and enter circulation in G0 phase ○ Naïve cells (condensed chromatin, little cytoplasm) ○ About twice as many CD4+ Naïve cell recognized MHC-antigen complex ○ Initiated primary response ○ After 48 hours, enlarges into blast cell and undergoes repeated rounds of cell ...
File - Pomp
File - Pomp

... • Neutrophils • 60-70% WBCs; engulf and destroy microbes at infected tissue Short lived • Monocytes • 5% WBCs; develop into…. – Macrophages 1)phagocytosis – 2)lysosomal enzymes destroy microbes ...
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Lymphopoiesis



Lymphopoiesis (lĭm'fō-poi-ē'sĭs) (or lymphocytopoiesis) is the generation of lymphocytes, one of the five types of white blood cell (WBC). It is more formally known as lymphoid hematopoiesis.Pathosis in lymphopoiesis leads to any of various lymphoproliferative disorders, such as the lymphomas and lymphoid leukemias.
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