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match-up
match-up

... white blood cells are helper cells and cytotoxic cells is an antigen presenting complex on a cell’s surface. A nearby T cell can detect the antigen displayed on the cell’s surface and initiate a response. These cells are part of the acquired immune system. They’re long lived cells that bear receptor ...
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... synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'oligoadenylates (2-5As). These molecules activate latent RNa ...
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... triggering signal is set off. The B cell now needs proteins produced by helper T cells to become fully activated. When this happens, the B cell starts to divide to produce clones of itself. During this process, two new cell types are created, plasma cells and B memory cells. The plasma cell is speci ...
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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... 5. Define epitope. 6. How hybridomas are selected? 7. Distinguish between cytokines and hormones. 8. Define antigens. 9. What are the two pathways involved in monoclonal antibodies? 10. What are cytotoxic T cells? Part B Answer the following each answer within 500 words. Draw diagrams wherever neces ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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