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... The poly(A) tail is bound by the poly(A)-binding protein (PABP), which is necessary for efficient translation (for reviews, see Jacobson, 1996; Sachs et al., 1997). In yeast, eIF4G was found to associate with PABP (Tarun and Sachs, 1996). The PABP-binding site was mapped to an N-terminal region prox ...
... The poly(A) tail is bound by the poly(A)-binding protein (PABP), which is necessary for efficient translation (for reviews, see Jacobson, 1996; Sachs et al., 1997). In yeast, eIF4G was found to associate with PABP (Tarun and Sachs, 1996). The PABP-binding site was mapped to an N-terminal region prox ...
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... Figure was assumed from textbook: Devlin, T. M. (editor): Textbook of Biochemistry with Clinical Correlations, 4th ed. Wiley-Liss, Inc., New York, 1997. ...
... Figure was assumed from textbook: Devlin, T. M. (editor): Textbook of Biochemistry with Clinical Correlations, 4th ed. Wiley-Liss, Inc., New York, 1997. ...
Chapter 5 Slides
... The Sequence of Amino Acids in a Protein • is a unique characteristic of every protein • is encoded by the nucleotide sequence of DNA • is thus a form of genetic information • is read from the amino terminus to the ...
... The Sequence of Amino Acids in a Protein • is a unique characteristic of every protein • is encoded by the nucleotide sequence of DNA • is thus a form of genetic information • is read from the amino terminus to the ...
Towards a molecular understanding of adaptive thermogenesis
... the obesity is associated with increased food intake. However, if food intake is restricted so that it equals that observed in controls, obesity still develops16. This increased storage of calories, during normal caloric intake, indicates that energy expenditure is decreased. These studies show that ...
... the obesity is associated with increased food intake. However, if food intake is restricted so that it equals that observed in controls, obesity still develops16. This increased storage of calories, during normal caloric intake, indicates that energy expenditure is decreased. These studies show that ...
Molecular Characterization of –Lactalbumin Folding Variants That
... main known function is to change the acceptor specificity of b-galactosyltransferase from GlcNAc to Glc, thus enabling the synthesis of lactose in milk (9, 10). The crystal structure of a-lactalbumin has been solved (11) (Fig. 1). It is a metalloprotein with high affinity for Ca21 and other divalent ...
... main known function is to change the acceptor specificity of b-galactosyltransferase from GlcNAc to Glc, thus enabling the synthesis of lactose in milk (9, 10). The crystal structure of a-lactalbumin has been solved (11) (Fig. 1). It is a metalloprotein with high affinity for Ca21 and other divalent ...
Modeling Multi-typed Structurally Viewed Chemicals with the UMLS
... set intersection.) All boldface terms are defined in the Glossary Appendix (available as an online data supplement at [email protected]). The largest collection of ISTs, 411 in total, exists for that part of the UMLS devoted to chemicals, where two or more ST assignments per concept are common. The 32 I ...
... set intersection.) All boldface terms are defined in the Glossary Appendix (available as an online data supplement at [email protected]). The largest collection of ISTs, 411 in total, exists for that part of the UMLS devoted to chemicals, where two or more ST assignments per concept are common. The 32 I ...
Plant biotin-containing carboxylases
... (b-CT). With the exception of Arabidopsis, all higher plants examined have multiple copies of the nuclear genes that code for these subunits. The occurrence of paralogous genes for each nuclear-coded subunit has been inferred from sequence heterogeneity among cDNAs [48,49] and analysis of expressed ...
... (b-CT). With the exception of Arabidopsis, all higher plants examined have multiple copies of the nuclear genes that code for these subunits. The occurrence of paralogous genes for each nuclear-coded subunit has been inferred from sequence heterogeneity among cDNAs [48,49] and analysis of expressed ...
Cress and Potato Soluble Epoxide Hydrolases
... isolated and cloned (18, 19), and recently a putative sEH cDNA was cloned from tobacco by Gou et al. (20). These plant genes code for proteins 30% shorter on the N-terminus than the mammalian sEH (Fig. 1), but they display significant homology to the C-terminal domain of the mammalian sEH that conta ...
... isolated and cloned (18, 19), and recently a putative sEH cDNA was cloned from tobacco by Gou et al. (20). These plant genes code for proteins 30% shorter on the N-terminus than the mammalian sEH (Fig. 1), but they display significant homology to the C-terminal domain of the mammalian sEH that conta ...
Capacitation-associated Changes in Protein
... different groups: modified TALP (Tyrode’s albumin lactate pyruvate) or TALP without one of the medium constituents (Ca2+, HCO3- and BSA). After incubation for the required time (0 h, 0.5 h, 1 h, 3 h, 5 h, and 7 h), sperm were removed for further experiment. The capacitation effect was assessed by CT ...
... different groups: modified TALP (Tyrode’s albumin lactate pyruvate) or TALP without one of the medium constituents (Ca2+, HCO3- and BSA). After incubation for the required time (0 h, 0.5 h, 1 h, 3 h, 5 h, and 7 h), sperm were removed for further experiment. The capacitation effect was assessed by CT ...
... Figure 2: Polarization curves for copper in 1 mol L-1 HNO3 solutions in the absence and presence of amino acids at 10 -3M. From Table 1, it was clearly seen that the presence of amino acids compounds at 10 -3 M reduces the corrosion rate of copper in nitric acid solution. The current density of the ...
General and Physiological Chemistry
... Define and illustrate by means of names and formulas what is meant by a salt. Write equations illustrating how salts may be prepared by the action of an acid on a metal, on a metal hydroxide, on a metal carbonate, and on a metal bicarbonate. State the difference between a strong electrolyte, a weak ...
... Define and illustrate by means of names and formulas what is meant by a salt. Write equations illustrating how salts may be prepared by the action of an acid on a metal, on a metal hydroxide, on a metal carbonate, and on a metal bicarbonate. State the difference between a strong electrolyte, a weak ...
Predicting the sidechain dihedral angle distributions
... of amino acids. We employ a simple approach: modeling amino acids as hard-spheres with stereochemical constraints on the bond lengths and angles. Briefly, using Val for illustration, our strategy is as follows. We first identify all occurrences of the amino acid of interest in the 1.0 Å Dunbrack da ...
... of amino acids. We employ a simple approach: modeling amino acids as hard-spheres with stereochemical constraints on the bond lengths and angles. Briefly, using Val for illustration, our strategy is as follows. We first identify all occurrences of the amino acid of interest in the 1.0 Å Dunbrack da ...
6b How to ID an Unk organism
... Individual tests can be performed in separate tubes (conventional method) or all the tests can be performed in one specially designed Enterotube (rapid identification method). Comparisons between rapid identification methods and conventional methods show that they are equally accurate. NOTE: Be able ...
... Individual tests can be performed in separate tubes (conventional method) or all the tests can be performed in one specially designed Enterotube (rapid identification method). Comparisons between rapid identification methods and conventional methods show that they are equally accurate. NOTE: Be able ...
Preference for and learning of amino acids in larval Drosophila
... Drosophila larvae, it is only known that they preferentially ingest amino acid-rich soybean rather than other tested foods (Ryuda et al., 2008), and that aspartic acid is a strong reward (Schleyer et al., 2015) (on glycine as a reward in honey bees, see Kim and Smith, 2000). Furthermore, Croset et a ...
... Drosophila larvae, it is only known that they preferentially ingest amino acid-rich soybean rather than other tested foods (Ryuda et al., 2008), and that aspartic acid is a strong reward (Schleyer et al., 2015) (on glycine as a reward in honey bees, see Kim and Smith, 2000). Furthermore, Croset et a ...
Bioorganometallic Chemistry - Chemistry and Biochemistry
... of hydrogenase active sites and those of other complex iron-sulfur enzymes and iron-sulfur mineral structures and reactivity have also been gaining interest. Given that complex iron-sulfur enzymes are involved with reactions such as reversible hydrogen oxidation, nitrogen fixation, and reversible car ...
... of hydrogenase active sites and those of other complex iron-sulfur enzymes and iron-sulfur mineral structures and reactivity have also been gaining interest. Given that complex iron-sulfur enzymes are involved with reactions such as reversible hydrogen oxidation, nitrogen fixation, and reversible car ...
Crystal structure of mouse coronavirus receptor
... mediates viral entry into host cells by functioning as a class I viral ...
... mediates viral entry into host cells by functioning as a class I viral ...
MS PowerPoint - Catalysis Eprints database
... Now catalysis is achieved, How specificity is achieved is the next question? ...
... Now catalysis is achieved, How specificity is achieved is the next question? ...
Assessing in silico the recruitment and functional spectrum of
... loci relevant for metabolite biosynthesis. Moreover, with recent genome editing and engineering techniques like CRISPR-Cas [3] allowing for rational pathway design, secondary metabolites are gaining new relevance [4]. Often, microbial secondary metabolites are derived by means of specific biosynthet ...
... loci relevant for metabolite biosynthesis. Moreover, with recent genome editing and engineering techniques like CRISPR-Cas [3] allowing for rational pathway design, secondary metabolites are gaining new relevance [4]. Often, microbial secondary metabolites are derived by means of specific biosynthet ...
Antioxidants Minerals B-Vitamins
... Methyl tert-Butyl Ether (MTBE) is a common gasoline additive used to increase octane ratings, and has been found to contaminate ground water supplies where gasoline is stored. Inhalation of MTBE may cause nose and throat irritation, as well as headaches, nausea, dizziness and mental confusion. Anima ...
... Methyl tert-Butyl Ether (MTBE) is a common gasoline additive used to increase octane ratings, and has been found to contaminate ground water supplies where gasoline is stored. Inhalation of MTBE may cause nose and throat irritation, as well as headaches, nausea, dizziness and mental confusion. Anima ...
Biochemical and Biophysical Research Communications
... implying that the sixth amino acids of fusaricidin analogs produced by P. polymyxa E681 may exist as an L-form, although all reported fusaricidins contain D-form alanines in their sixth amino acid residues. However, we do not exclude the possibility that the sixth A domain of FusA can directly recog ...
... implying that the sixth amino acids of fusaricidin analogs produced by P. polymyxa E681 may exist as an L-form, although all reported fusaricidins contain D-form alanines in their sixth amino acid residues. However, we do not exclude the possibility that the sixth A domain of FusA can directly recog ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.