The use of the movie "Lorenzo`s Oil" as a Teaching Tool
... hydrogen. Hydrogenation removes the kinks in the fatty acid chain and allows the triglycerides to pack together well. Thus, you have a solid form that can be spread on toast. However, the industrial process also produces "trans" double bonds in the fatty acids of the triglycerides. These "trans" fat ...
... hydrogen. Hydrogenation removes the kinks in the fatty acid chain and allows the triglycerides to pack together well. Thus, you have a solid form that can be spread on toast. However, the industrial process also produces "trans" double bonds in the fatty acids of the triglycerides. These "trans" fat ...
Sources of blood glucose
... blood due to glycogen breakdown & gluconeogenesis ↑Triglyceride synthesis ↑Ketones released ...
... blood due to glycogen breakdown & gluconeogenesis ↑Triglyceride synthesis ↑Ketones released ...
Lysine-Restricted Diet as Adjunct Therapy for Pyridoxine
... outcomes in seven children with ATQ deficiency (van Karnebeek et al. 2012). The results show that dietary lysine restriction (evidence level IV) in these children: (1) is tolerated without short-term adverse effects; (2) leads to decrease of potentially neurotoxic biomarkers in different body compar ...
... outcomes in seven children with ATQ deficiency (van Karnebeek et al. 2012). The results show that dietary lysine restriction (evidence level IV) in these children: (1) is tolerated without short-term adverse effects; (2) leads to decrease of potentially neurotoxic biomarkers in different body compar ...
Soft X-Ray-Induced Decomposition of Amino Acids: An XPS, Mass
... Commercially available polycrystalline powders of amino acids (Sigma-Aldrich Chemie GmbH, purity .98%) were finely ground in a mortar and pressed into sputter-cleaned indium foil to form a uniform layer. Excess powder, which did not adhere to the foil, was removed with a brush. Samples were loaded i ...
... Commercially available polycrystalline powders of amino acids (Sigma-Aldrich Chemie GmbH, purity .98%) were finely ground in a mortar and pressed into sputter-cleaned indium foil to form a uniform layer. Excess powder, which did not adhere to the foil, was removed with a brush. Samples were loaded i ...
PDF format - JOP. Journal of the Pancreas
... Plasma Amino Acid Levels In all, 17 amino acids were detected and identified. The distribution pattern of these amino acids is given in Table 2. As compared to the healthy controls, the chronic pancreatitis patients had lower concentrations of aspartate, serine, histidine, arginine, threonine, tyros ...
... Plasma Amino Acid Levels In all, 17 amino acids were detected and identified. The distribution pattern of these amino acids is given in Table 2. As compared to the healthy controls, the chronic pancreatitis patients had lower concentrations of aspartate, serine, histidine, arginine, threonine, tyros ...
Document
... multiplications of the PAM 1 matrix, since the probability of two independent events is equal to the product of the probabilities of each individual event While for the PAM 1 matrix it holds that a mutational event corresponds to a difference of 1%, this is not true for higher order PAM matrices In ...
... multiplications of the PAM 1 matrix, since the probability of two independent events is equal to the product of the probabilities of each individual event While for the PAM 1 matrix it holds that a mutational event corresponds to a difference of 1%, this is not true for higher order PAM matrices In ...
DESIGNING OF A POTENT ANALOG AGAINST DRUG RESISTANT HIV-1 PROTEASE:... STUDY Research Article
... pocket is measured by ProtScale tool. The FASTA sequences of the protease enzyme (1HPV) were pasted in the box provided followed by their submission.The tool plots the hydrophobic values of each amino acids present in the sequence in the form of graph as well as individual amino acids also. Hydropho ...
... pocket is measured by ProtScale tool. The FASTA sequences of the protease enzyme (1HPV) were pasted in the box provided followed by their submission.The tool plots the hydrophobic values of each amino acids present in the sequence in the form of graph as well as individual amino acids also. Hydropho ...
Deep mutational scanning reveals tail anchor
... charges at the membrane interface. Our work provides the first high-resolution analysis ...
... charges at the membrane interface. Our work provides the first high-resolution analysis ...
Full-Text PDF
... Plasmodesmata (PDs) are dynamic symplasmic nanochannels that are localized in the plant cell wall and connect the cytoplasm spaces and endoplasmic reticulum compartments of adjacent cells [30–34]. PDs mediate the symplasmic movement of small molecules such as water, ions, small nucleotides, phytohor ...
... Plasmodesmata (PDs) are dynamic symplasmic nanochannels that are localized in the plant cell wall and connect the cytoplasm spaces and endoplasmic reticulum compartments of adjacent cells [30–34]. PDs mediate the symplasmic movement of small molecules such as water, ions, small nucleotides, phytohor ...
Full-Text PDF
... forces [2,4]. The energy associated with an H bond is 2–10 kcal/mol. While this may seem insignificant it is important to remember that these bonds are flexible and dynamic in that they are constantly broken and reformed under a range of temperatures and physiological conditions [2]. There is quite ...
... forces [2,4]. The energy associated with an H bond is 2–10 kcal/mol. While this may seem insignificant it is important to remember that these bonds are flexible and dynamic in that they are constantly broken and reformed under a range of temperatures and physiological conditions [2]. There is quite ...
Atlas of Antinuclear Antibodies
... 58. Vazquez-Abad D, Carson JH, Rothfield N. Localization of histidyl-tRNA synthetase (Jo-1) in human laryngeal epithelial carcinoma cell line (HEp-2 cells). Cell Tissue Res. 286, 487-91, 1996 [PMID:8929351] 59. Friedman AW, Targoff IN, Arnett FC. Interstitial lung disease with autoantibodies again ...
... 58. Vazquez-Abad D, Carson JH, Rothfield N. Localization of histidyl-tRNA synthetase (Jo-1) in human laryngeal epithelial carcinoma cell line (HEp-2 cells). Cell Tissue Res. 286, 487-91, 1996 [PMID:8929351] 59. Friedman AW, Targoff IN, Arnett FC. Interstitial lung disease with autoantibodies again ...
Differential Regulation of a-Lactalbumin and
... ethanol, dissolved in sterile demineralized water, and stored at —70° on used directly in the translation assay. Concentrations of RNA-containing fractions were deter mined by absorbance at 260 pm on the assumption that 1 mg/mi = 20 A2@:A280 ...
... ethanol, dissolved in sterile demineralized water, and stored at —70° on used directly in the translation assay. Concentrations of RNA-containing fractions were deter mined by absorbance at 260 pm on the assumption that 1 mg/mi = 20 A2@:A280 ...
Nutricoll Marine Collagen brochure
... 5. ADDED VALUE FOR THE MUSCULOSKELETAL SYSTEM Products containing active collagen peptides have long been marketed in the US and European pharmaceutical and food markets. Many scientific and preclinical studies show various positive effects on tendon flexibility, ligament stability, muscle and bone ...
... 5. ADDED VALUE FOR THE MUSCULOSKELETAL SYSTEM Products containing active collagen peptides have long been marketed in the US and European pharmaceutical and food markets. Many scientific and preclinical studies show various positive effects on tendon flexibility, ligament stability, muscle and bone ...
A C-terminus Mitochondrial-localization Region and BH3 Domain of
... Apoptosis plays an crucial role in normal development and maintenance of tissue homeostasis. It is required to eliminate unnecessary tissue during development, and later on in an organism's lifespan it is necessary to destroy damaged or mutated cells (Kerr et al. 1972; Oppenheim 1991; Yoshida et al. ...
... Apoptosis plays an crucial role in normal development and maintenance of tissue homeostasis. It is required to eliminate unnecessary tissue during development, and later on in an organism's lifespan it is necessary to destroy damaged or mutated cells (Kerr et al. 1972; Oppenheim 1991; Yoshida et al. ...
SOLID PHASE PEPTIDE SYNTHESIS
... Although in general acidolytic cleavage from the resin is the method of choice to release the peptide at the end of the synthesis, a broad range of resins susceptible to be cleaved by nucleophiles such as the “Kaiser oxime resin” [26] and the p-carboxybenzyl alcohol linker [27] or by photolysis [28] ...
... Although in general acidolytic cleavage from the resin is the method of choice to release the peptide at the end of the synthesis, a broad range of resins susceptible to be cleaved by nucleophiles such as the “Kaiser oxime resin” [26] and the p-carboxybenzyl alcohol linker [27] or by photolysis [28] ...
COMPARATIVE HYDROLYSIS OF GELATIN BY PEPSIN, TRYPSIN
... number of linkages split was the same in all the solutions, different ones had been split in each case. They found that the course of the reaction was similar with pepsin and acid, and with trypsin and alkali. The study of the hydrolytic products of trypsin and pepsin leads to the same conclusion? I ...
... number of linkages split was the same in all the solutions, different ones had been split in each case. They found that the course of the reaction was similar with pepsin and acid, and with trypsin and alkali. The study of the hydrolytic products of trypsin and pepsin leads to the same conclusion? I ...
The monocarboxylate transporter family
... more sensitive than MCT1 to inhibition by a range of inhibitors including CHC, DBDS, and DIDS but insensitive to the organomercurial reagent pCMBS (25, 26). Subsequent work in this laboratory has shown that pCMBS actually inhibits MCT1 by binding to the ancillary protein, basigin (see Some MCTs Requ ...
... more sensitive than MCT1 to inhibition by a range of inhibitors including CHC, DBDS, and DIDS but insensitive to the organomercurial reagent pCMBS (25, 26). Subsequent work in this laboratory has shown that pCMBS actually inhibits MCT1 by binding to the ancillary protein, basigin (see Some MCTs Requ ...
PROTEIN SUBCELLULAR LOCALIZATION
... with BLAST, WoLF PSORT yields a cross-validated accuracy of 83%, eliminating about 1/3 of the errors made when using BLAST alone. For 12771 animal proteins a combined accuracy of 95.6% is obtained, eliminating 1/4 of BLAST alone errors, and for 2333 plant proteins the accuracy can be improved to 86% ...
... with BLAST, WoLF PSORT yields a cross-validated accuracy of 83%, eliminating about 1/3 of the errors made when using BLAST alone. For 12771 animal proteins a combined accuracy of 95.6% is obtained, eliminating 1/4 of BLAST alone errors, and for 2333 plant proteins the accuracy can be improved to 86% ...
tRNA
... a specific amino acid (aa) for which it harbors an anticodon generates the corresponding aminoacyl-tRNA (aa-tRNA) conjugate in a process referred to as “aminoacylation” - How should the tRNA attached to the following amino acids be nomenclatured (or named)? Arg, Glu, and Trp - On the other hand, tRN ...
... a specific amino acid (aa) for which it harbors an anticodon generates the corresponding aminoacyl-tRNA (aa-tRNA) conjugate in a process referred to as “aminoacylation” - How should the tRNA attached to the following amino acids be nomenclatured (or named)? Arg, Glu, and Trp - On the other hand, tRN ...
Lecture 9 - Fatty Acid Metabolism - chem.uwec.edu
... Fatty acid are synthesized and degraded by different pathways. Synthesis takes place in the cytosol. Intermediates are attached to the acyl carrier protein (ACP). In higher organisms, the active sites for the synthesis reactions are all on the same polypeptide. The activated donor in the synthesis i ...
... Fatty acid are synthesized and degraded by different pathways. Synthesis takes place in the cytosol. Intermediates are attached to the acyl carrier protein (ACP). In higher organisms, the active sites for the synthesis reactions are all on the same polypeptide. The activated donor in the synthesis i ...
Enzyme promiscuity: evolutionary and mechanistic aspects
... Mechanisms of promiscuous enzyme activities. (a) PON1 is the best-characterized member of a family of enzymes, found in all mammals and numerous other organisms. The native function of mammalian PONs was shown to be that of a lipo-lactonase [59,69]. The main active site feature is the catalytic calc ...
... Mechanisms of promiscuous enzyme activities. (a) PON1 is the best-characterized member of a family of enzymes, found in all mammals and numerous other organisms. The native function of mammalian PONs was shown to be that of a lipo-lactonase [59,69]. The main active site feature is the catalytic calc ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.