 
									
								
									File
									
... sites” on their surfaces that interact with the substrate(s)  As the substrate enters this active site it induces the enzyme to change shape so that the active site fits even more snugly around the substrate (clasping handshake)  This “induced-fit” strains the pre-existing bonds within the substra ...
                        	... sites” on their surfaces that interact with the substrate(s)  As the substrate enters this active site it induces the enzyme to change shape so that the active site fits even more snugly around the substrate (clasping handshake)  This “induced-fit” strains the pre-existing bonds within the substra ...
									Protein Modification, targeting and degradation Protein modification
									
... • protein contains a stop-transfer sequence which is too hydrophobic to emerge into aqueous environment of ER lumen • stop-transfer sequence therefore gets stuck in membrane • ribosome lets go of translocon, finishes job in cytoplasm • translocon dissociates, leaves protein embedded in membrane ...
                        	... • protein contains a stop-transfer sequence which is too hydrophobic to emerge into aqueous environment of ER lumen • stop-transfer sequence therefore gets stuck in membrane • ribosome lets go of translocon, finishes job in cytoplasm • translocon dissociates, leaves protein embedded in membrane ...
									Chapter 2 - SCHOOLinSITES
									
... • When two monosaccharides are joined together they form a "disaccharide". This linking of two sugars involves the removal of a molecule of H2O (water) and is therefore called a "dehydration linkage". The reaction is called "dehydration synthesis". ...
                        	... • When two monosaccharides are joined together they form a "disaccharide". This linking of two sugars involves the removal of a molecule of H2O (water) and is therefore called a "dehydration linkage". The reaction is called "dehydration synthesis". ...
									Biochemistry LTF
									
... and a base (fig. 13) - four bases in DNA in different orders code for all characteristics of life! - adenine, thymine, guanine, and cytosine (fig. 15) ...
                        	... and a base (fig. 13) - four bases in DNA in different orders code for all characteristics of life! - adenine, thymine, guanine, and cytosine (fig. 15) ...
									Slides/AVS 504 Met Fri 2013 pt 2
									
... Protein Digestion in Phases 1. Gastric hydrolysis of peptide linkages in the protein 2. Digestion of protein to smaller peptides by action of pancreatic proteases, which are secreted as zymogens and activated in the lumen of the small intestine 3. Hydrolysis of peptide linkages in oligopeptides by ...
                        	... Protein Digestion in Phases 1. Gastric hydrolysis of peptide linkages in the protein 2. Digestion of protein to smaller peptides by action of pancreatic proteases, which are secreted as zymogens and activated in the lumen of the small intestine 3. Hydrolysis of peptide linkages in oligopeptides by ...
									COMMON SUBSTANCES ESSENTIAL TO LIVING THINGS
									
... selenium deficiency in humans can be linked to cancer and heart disease. ¢ Selenium, along with vitamin E, helps protect cell membranes from damage caused by hydrogen peroxide, a poison that is produced by some chemical reactions in cells. ...
                        	... selenium deficiency in humans can be linked to cancer and heart disease. ¢ Selenium, along with vitamin E, helps protect cell membranes from damage caused by hydrogen peroxide, a poison that is produced by some chemical reactions in cells. ...
									The Raw and the Cooked
									
... Fibrous proteins are found in hair, fingernails, animal claws and fur among other things. These proteins are strong because the individual protein molecules form parallel strands which twist together. Globular protein molecules work differently. A globular molecule twists and folds upon itself, usin ...
                        	... Fibrous proteins are found in hair, fingernails, animal claws and fur among other things. These proteins are strong because the individual protein molecules form parallel strands which twist together. Globular protein molecules work differently. A globular molecule twists and folds upon itself, usin ...
									Chapter 5 Proteins: Primary Structure
									
... It has been a long-standing goal in biochemistry to relate the structure of a protein to its function. Although a complete structural analysis of a protein is very complex, it begins with the sequence of amino acid residues from N to C terminals. This sequence defines the primary, or covalent, struc ...
                        	... It has been a long-standing goal in biochemistry to relate the structure of a protein to its function. Although a complete structural analysis of a protein is very complex, it begins with the sequence of amino acid residues from N to C terminals. This sequence defines the primary, or covalent, struc ...
									Huang, David, Center for Structural Biochemistry
									
...  Structure Determination – The electron density data was used to determine the structure of the proteins in complex with the ligands using the COOT software.  Analysis – The specific hydrogen bonds or hydrophobic interactions around the ligand binding pocket were analyzed after the structure had b ...
                        	...  Structure Determination – The electron density data was used to determine the structure of the proteins in complex with the ligands using the COOT software.  Analysis – The specific hydrogen bonds or hydrophobic interactions around the ligand binding pocket were analyzed after the structure had b ...
									Exam Name___________________________________
									
... D) hydrolyzing the protein with dilute acid E) protecting the N-terminal of the peptide ...
                        	... D) hydrolyzing the protein with dilute acid E) protecting the N-terminal of the peptide ...
									Chapter 15: Protein Synthesis
									
... • Each tRNA in turn (with its own amino acid) lines up with the mRNA in the ribosome and an amino acids are joined together in a long polypeptide line which will form the protein • This process continues until the stop codon on the mRNA is reached at which point all the translation machinery separat ...
                        	... • Each tRNA in turn (with its own amino acid) lines up with the mRNA in the ribosome and an amino acids are joined together in a long polypeptide line which will form the protein • This process continues until the stop codon on the mRNA is reached at which point all the translation machinery separat ...
									p-5-wwu_wp3_talk-wagenknecht-kolkenbrock
									
... suitable combination of expression host and vector system. There are numerous eukaryotic as well as prokaryotic systems on the market, where the latter are the most frequently used ones. This is mostly due to the short generation cycle of prokaryotes and a huge variety of molecular tools available. ...
                        	... suitable combination of expression host and vector system. There are numerous eukaryotic as well as prokaryotic systems on the market, where the latter are the most frequently used ones. This is mostly due to the short generation cycle of prokaryotes and a huge variety of molecular tools available. ...
									Biomolecules - Good Earth School
									
... as a neutral dipolar ion. This pH is known as Isoelectric point. Denaturation of proteins: Proteins are very sensitive to the action of heat, acids, alkalis and electrolytes. When they are subjected to heat, acid and alkali they undergo coagulation to form fibrous proteins which are insoluble in wat ...
                        	... as a neutral dipolar ion. This pH is known as Isoelectric point. Denaturation of proteins: Proteins are very sensitive to the action of heat, acids, alkalis and electrolytes. When they are subjected to heat, acid and alkali they undergo coagulation to form fibrous proteins which are insoluble in wat ...
									Chapter 34-4B: Second Messengers
									
... Some of membrane proteins are receptors of signal transduction. Hormones, growth factors and neurotransmitters bind the signal transduction receptors located on the surface of target cell membranes. Signals are transferred to the inside of target cell through the transmembrane receptor protein. Sign ...
                        	... Some of membrane proteins are receptors of signal transduction. Hormones, growth factors and neurotransmitters bind the signal transduction receptors located on the surface of target cell membranes. Signals are transferred to the inside of target cell through the transmembrane receptor protein. Sign ...
									Ruth Perez Associate Professor, Texas Tech University Health
									
... The Perez lab studies the normal function of proteins that have been implicated in neurological diseases, utilizing cellular and transgenic models manipulated by transfection or viral transduction. Key projects are related to Parkinson’s disease (PD), Dementia with Lewy Bodies (DLB), Alzheimer’s dis ...
                        	... The Perez lab studies the normal function of proteins that have been implicated in neurological diseases, utilizing cellular and transgenic models manipulated by transfection or viral transduction. Key projects are related to Parkinson’s disease (PD), Dementia with Lewy Bodies (DLB), Alzheimer’s dis ...
									File - Biology Class With Mrs. Caskey
									
... ____________________ 1. This measures the hydrogen ion level of a solution. ____________________ 2. What kind of solution contains more hydrogen ions than hydroxide ions? ____________________ 3. This is the name for a compound with many sugar subunits linked together. ____________________ 4. What ar ...
                        	... ____________________ 1. This measures the hydrogen ion level of a solution. ____________________ 2. What kind of solution contains more hydrogen ions than hydroxide ions? ____________________ 3. This is the name for a compound with many sugar subunits linked together. ____________________ 4. What ar ...
									lecture notes-molecular biology-central dogma
									
... mRNA template. - The information contained in the nucleotide sequence of the mRNA is read as three letter words (triplets), called codons. - Each word stands for one amino acid. - During translation are linked together to form a chain which will later be folded into a protein. ...
                        	... mRNA template. - The information contained in the nucleotide sequence of the mRNA is read as three letter words (triplets), called codons. - Each word stands for one amino acid. - During translation are linked together to form a chain which will later be folded into a protein. ...
									Recombinant Human Tumor Necrosis Factor alpha
									
... is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Recombinant Human TNF-alpha is a 17.4 kDa protein containing 157 amino acid residues. Source ...
                        	... is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. Recombinant Human TNF-alpha is a 17.4 kDa protein containing 157 amino acid residues. Source ...
									several polypeptide chains
									
... interlocking rings. (d.) They all are important as energy storage molecules. (e.) None of the answers is correct. 11. In the digestive process, the macromolecules are broken down into small molecules that can cross cell membranes. This process is called (a.) hydrolysis (b.) dehydration synthes ...
                        	... interlocking rings. (d.) They all are important as energy storage molecules. (e.) None of the answers is correct. 11. In the digestive process, the macromolecules are broken down into small molecules that can cross cell membranes. This process is called (a.) hydrolysis (b.) dehydration synthes ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									