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Notes on chemistry of life
Notes on chemistry of life

Chapter 3 Review Guide
Chapter 3 Review Guide

... - This compound is made of adenine (base), ribose (sugar), and phosphates - Adenine and ribose = adenosine - ATP to ADP to AMP = energy released from the phosphate bonds to be used by the body - AMP to ADP to ATP = energy stored in the phosphate bonds to be used later ...
carbon - Palmer ISD
carbon - Palmer ISD

... threads to be used as fibers ...
UNIT 2 Targets - Biochemistry
UNIT 2 Targets - Biochemistry

... I can describe the specifics of enzyme structure and function: identify the substrate(s), binding at the active site, identify the product(s) formed, and how the enzyme can be re-used after the products are formed. I can explain that the activity of enzymes is affected by changes in temperature and ...
Characterizing the Secreted Proteome of Mycobacterium
Characterizing the Secreted Proteome of Mycobacterium

... an alternative secretion system called ESX-1 (Figure 1, left). This system is required for virulence and has very few characterized substrates. Here, we employed iTRAQ® reagent labeling coupled with LC/MS/MS analysis to identify, quantify and characterize the secreted proteome from M. tuberculosis ( ...
File
File

E. Aminoglycosides
E. Aminoglycosides

... metabolic functions as well as for cell integrity.  Bacterial cell uses ribosomes to synthesize proteins.  Targeting protein biosynthesis will produce bactericidal agents in most of the cases.  Why targeting the bacterial protein synthesis will be selective:  Different diffusion rates between ba ...
Name
Name

... 2. Molecules and atoms from the environment are necessary to build new molecules  C,H,N,O,P, and S are the most common elements in living organisms  Carbon – found in all organic molecules, builds backbone of many molecules (know where it is found in the four macromolecules); cycles via Carbon Cyc ...
CHEMICAL COMPOUNDS OF LIFE
CHEMICAL COMPOUNDS OF LIFE

... called monomers join together to form polymers. This is called polymerization. • The millions of carbon containing compounds are classified into four groups of organic compounds: carbohydrates, lipids, nucleic acids, and proteins. ...
QUESTIONS
QUESTIONS

... mRNA is transcribed from DNA. Single-stranded mRNA ‘carries the code’ to the site of protein synthesis in the cytoplasm. Here, tRNA (transfer RNA) and mRNA control protein production by the process of translation. ...
Three-Dimensional Structure of the Muscle Fatty-Acid
Three-Dimensional Structure of the Muscle Fatty-Acid

MULTIPLE CHOICE. Choose the one alternative that best completes
MULTIPLE CHOICE. Choose the one alternative that best completes

... 61) Which of the following statements is true? A) Ribosomes are composed of protein and lipid. B) The compositions of the intracellular fluid and extracellular fluid are identical due to the free movement of molecules across the cell membrane. C) The Golgi apparatus contains the enzyme catalase to b ...
Computational Protein Design as a Cost Function Network
Computational Protein Design as a Cost Function Network

... of protein folding [28]: the three-dimensional structure is known and we have to find amino acid sequences that folds into it. It can also be considered as a highly combinatorial variant of side-chain positioning [35] because of possible amino acid changes. Different computational methods have been ...
Lecture-1-molbio
Lecture-1-molbio

... Interconvert small molecules Immune response: bind and degrade invaders Maintain circadian rhythm & other clocks ...
Secondary Metabolites and Building Blocks
Secondary Metabolites and Building Blocks

... May be more prevalent or unique to certain genus, species, and similar compounds occur within genuses and families Often have vital functions in the source • attractants for propagation of species • defense against predators • signaling May have useful nutritional benefits to humans/other organisms ...
Station 1: Carbon Compounds
Station 1: Carbon Compounds

... nitrogen, carbon, and phosphorus. Nucleotides are the monomers that make up nucleic acids. Each nucleotide consists of a 5-carbon sugar, a phosphate group, and a nitrogenous base. Nucleic acids store and transmit hereditary, or genetic, information. There are two kinds of nucleic acids: ribonucleic ...
Polymers and Amino Acids
Polymers and Amino Acids

... Hydrolysis of peptide bonds A peptide bond can be split by refluxing with hydrochloric acid. During hydrolysis, the water molecule adds across the peptide bond, forming a mixture of the two amino acids. ...
Chapter 7
Chapter 7

... DNA coding sequence for signal peptide that facilitates the secretion of protein through cell membranes and external environment. • Other sequence that protect the recombinant protein from proteolytic degradation, and provide a affinity tag is also used. • These extra amino acid sequences are equipp ...
Chemical Basis of Life packet #2-1.answer.key
Chemical Basis of Life packet #2-1.answer.key

... o Higher concentration of substrate means more substrate finding the active site. o Production speeds up. ...
Additional file 11 cd00120: MCM1, Agamous, Deficiens, and SRF
Additional file 11 cd00120: MCM1, Agamous, Deficiens, and SRF

... sites which were shown to be in close contact with substrate and/or cofactor by previous computational and experimental studies (26-31). Serine protease Serine proteases, such as trypsin, chymotrypsin and elastases have similar catalytic mechanisms but have different preferences for the bonds that t ...
Document
Document

... a. The acids in lemon or lime juice break down the hydrogen bonds between polar residues and disrupt salt bridges, which denature the proteins of the fish. b. The heat during baking breaks apart hydrogen bonds and hydrophobic interactions between nonpolar residues in the milk proteins. When the milk ...
Datasheet - Santa Cruz Biotechnology
Datasheet - Santa Cruz Biotechnology

... MND1 (meiotic nuclear division protein 1 homolog), also known as GAJ, is a 205 amino acid nuclear protein required for proper homologous chromosome pairing and meiotic double-strand break repair. Belonging to the MND1 family, MND1 localizes to chromatin during meiotic prophase and preferentially bin ...
Izzeddin M - Al-Isra University
Izzeddin M - Al-Isra University

50695_1 - Griffith Research Online
50695_1 - Griffith Research Online

Nutritional Content - Harmony Pediatric Therapy
Nutritional Content - Harmony Pediatric Therapy

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Proteolysis



Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.
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