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... (21), and the human PLZF protein, which is occasionally involved in chromosomal translocations in human promyelocytic leukemia (22). The regions of NH2-terminal homology among ZFPJS, ttk, Br-c, PLZF, and BCL-6 also share homology with viral proteins (for example, VA55R) of the poxvirus family (23) a ...
... (21), and the human PLZF protein, which is occasionally involved in chromosomal translocations in human promyelocytic leukemia (22). The regions of NH2-terminal homology among ZFPJS, ttk, Br-c, PLZF, and BCL-6 also share homology with viral proteins (for example, VA55R) of the poxvirus family (23) a ...
Learning Objectives
... 15. Explain how RNA is modified after transcription in eukaryotic cells. 16. Define and explain the role of ribozymes. 17. Describe the functional and evolutionary significance of introns. 18. Explain why, due to alternative RNA splicing, the number of different protein products an organism can prod ...
... 15. Explain how RNA is modified after transcription in eukaryotic cells. 16. Define and explain the role of ribozymes. 17. Describe the functional and evolutionary significance of introns. 18. Explain why, due to alternative RNA splicing, the number of different protein products an organism can prod ...
Protein contact prediction from amino acid co
... Deep learning has strong advantages over handcrafted processing pipelines and is setting new performance records and bringing new insights in the biomedical community [12, 13]. However, parts of the community are adopting deep learning with certain hesitation, even in areas where it is essential for ...
... Deep learning has strong advantages over handcrafted processing pipelines and is setting new performance records and bringing new insights in the biomedical community [12, 13]. However, parts of the community are adopting deep learning with certain hesitation, even in areas where it is essential for ...
Gizmos Protein Synthesis WS
... of amino acids grows, it tends to coil and form a three-dimensional shape. The complex shape that results determines the properties of the protein. Proteins have a wide variety of structures and perform many essential functions in living things. A sequence of DNA that codes for a specific protein is ...
... of amino acids grows, it tends to coil and form a three-dimensional shape. The complex shape that results determines the properties of the protein. Proteins have a wide variety of structures and perform many essential functions in living things. A sequence of DNA that codes for a specific protein is ...
Translation | Principles of Biology from Nature Education
... are a few exceptions such as mitochondria, chloroplasts and some prokaryotes. However, it is clear that the exceptions are very few and affect very few codons. Furthermore, all known genetic codes are more similar than different to each other, which supports the assertion that all life started from ...
... are a few exceptions such as mitochondria, chloroplasts and some prokaryotes. However, it is clear that the exceptions are very few and affect very few codons. Furthermore, all known genetic codes are more similar than different to each other, which supports the assertion that all life started from ...
Sagri Eftymia
... the mass rearing and releasing of sterilized insects in nature. This method has been successfully used to control other insects (eg. Mediterranean fly) in many regions worldwide, however the SIT has not been successfully applied in the olive fly yet. As has been shown in many cases, the successful a ...
... the mass rearing and releasing of sterilized insects in nature. This method has been successfully used to control other insects (eg. Mediterranean fly) in many regions worldwide, however the SIT has not been successfully applied in the olive fly yet. As has been shown in many cases, the successful a ...
Dietary plant-protein substitution affects hepatic metabolism in
... profile changed in response to the alteration in the diet. A number of metabolic pathways were identified as sensitive to the protein source substitution. These included pathways involved in primary energy generation, maintenance of reducing potential, bile acid synthesis, and transport and cellular ...
... profile changed in response to the alteration in the diet. A number of metabolic pathways were identified as sensitive to the protein source substitution. These included pathways involved in primary energy generation, maintenance of reducing potential, bile acid synthesis, and transport and cellular ...
High-School Football Athletes: A Proper Nutrition Guide
... may be needed in much higher amounts. Data from studies in adults show that plasma levels of glutamine decline during acute stress and illness. Glutamine makes up roughly 60% of the amino acid pool and skeletal muscle. Therefore, the regulation of intramuscular glutamine has significant effects on s ...
... may be needed in much higher amounts. Data from studies in adults show that plasma levels of glutamine decline during acute stress and illness. Glutamine makes up roughly 60% of the amino acid pool and skeletal muscle. Therefore, the regulation of intramuscular glutamine has significant effects on s ...
Protein oxidation and cellular homeostasis: Emphasis
... 3. Protein oxidation While there are many types of oxidative damage, increasing evidence suggest an important role for protein oxidation in aging and multiple diseases [37,54–56]. The importance of protein oxidation towards cellular homeostasis derives from the fact that proteins serve vital roles i ...
... 3. Protein oxidation While there are many types of oxidative damage, increasing evidence suggest an important role for protein oxidation in aging and multiple diseases [37,54–56]. The importance of protein oxidation towards cellular homeostasis derives from the fact that proteins serve vital roles i ...
cytology_enzyme_13
... The catalytic cycle of an enzyme 1 Substrates enter active site; enzyme changes shape so its active site embraces the substrates (induced fit). ...
... The catalytic cycle of an enzyme 1 Substrates enter active site; enzyme changes shape so its active site embraces the substrates (induced fit). ...
FIBROUS PROTEINS
... • α₁-antitrypsin is a protein secreted mainly by liver. It is also secreted by blood cells monocytes and macrophages. • It is present in blood and other body fluids. • It inhibits a number of proteolytic enzymes (proteases or proteinases) that destroy proteins. • Role of α₁-AT in the lungs: in the n ...
... • α₁-antitrypsin is a protein secreted mainly by liver. It is also secreted by blood cells monocytes and macrophages. • It is present in blood and other body fluids. • It inhibits a number of proteolytic enzymes (proteases or proteinases) that destroy proteins. • Role of α₁-AT in the lungs: in the n ...
BIO 322_Rec_4part2_Spring 2013
... • Trypsinogen to trypsin via enteropeptidase secreted from SI. Free trypsin further catalyzes trypsinogen to trypsin, also activates chymotrypsinogen, procarboxypeptidases and proelastase. ...
... • Trypsinogen to trypsin via enteropeptidase secreted from SI. Free trypsin further catalyzes trypsinogen to trypsin, also activates chymotrypsinogen, procarboxypeptidases and proelastase. ...
Print - Circulation Research
... effects on lysosomal function might be slow to develop, we chose to use an in vitro model which can function stably for many hours to days, i.e., the fetal mouse heart in organ culture.2 A second problem in approaching this question is to choose appropriate agents to interfere selectively with lysos ...
... effects on lysosomal function might be slow to develop, we chose to use an in vitro model which can function stably for many hours to days, i.e., the fetal mouse heart in organ culture.2 A second problem in approaching this question is to choose appropriate agents to interfere selectively with lysos ...
Essential Cell Biology (3rd ed.)
... acids, tend to be forced together to minimize their disruptive effect on the hydrogen-bonded network of the surrounding water molecules (see Panel 2–2, pp. 66–67). Therefore, an important factor governing the folding of any protein is the distribution of its polar and nonpolar amino acids. The nonpo ...
... acids, tend to be forced together to minimize their disruptive effect on the hydrogen-bonded network of the surrounding water molecules (see Panel 2–2, pp. 66–67). Therefore, an important factor governing the folding of any protein is the distribution of its polar and nonpolar amino acids. The nonpo ...
Equilibrium and Free Energy of Protein Denaturation
... model and show maximum differences in molar absorbtivity at 287, 292, 292 and 409 nm respectively. Chromophores for ribonuclease A, lysozyme, and α-lactalbumin are aromatic amino acids while the chromophore for myoglobin is heme. ...
... model and show maximum differences in molar absorbtivity at 287, 292, 292 and 409 nm respectively. Chromophores for ribonuclease A, lysozyme, and α-lactalbumin are aromatic amino acids while the chromophore for myoglobin is heme. ...
Supplementary Figure 1
... evolution; therefore the branch lengths correspond to amino acid substitutions per time unit. Evidently, UbS27a domains are less conserved than ribosomal S27a domains or homologs to SUMO1, despite the presence of a hypervariable loop at the N-terminus of SUMO1. Particularly indicative of a high rate ...
... evolution; therefore the branch lengths correspond to amino acid substitutions per time unit. Evidently, UbS27a domains are less conserved than ribosomal S27a domains or homologs to SUMO1, despite the presence of a hypervariable loop at the N-terminus of SUMO1. Particularly indicative of a high rate ...
Nucleic acids
... hydrogenation. This process increases the shelf life of the fats, however this process places the hydrogen on opposite sides of the fatty acid making it inflexible. The more inflexible the fatty acid the more unhealthy the fat. ...
... hydrogenation. This process increases the shelf life of the fats, however this process places the hydrogen on opposite sides of the fatty acid making it inflexible. The more inflexible the fatty acid the more unhealthy the fat. ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.