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Plasma membrane Affect shape and function Anchor protein to the

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NOTE: The provided figures may be useful and beneficial. Use them
NOTE: The provided figures may be useful and beneficial. Use them

... 7. The polypeptide chain that makes up a tight junction weaves back & forth through the membrane 4 times, with 2 extra-cellular loops, and 1 loop plus short C-terminal and N-terminal tails in the cytoplasm. Looking at Figure 5.17, what would you predict about the amino acid sequence of each region n ...
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Proteolysis



Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.
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