Cholesterol a jeho transport
... -facilitate the solubilization of dietary lipids during the process of digestion by promoting micelle formation ...
... -facilitate the solubilization of dietary lipids during the process of digestion by promoting micelle formation ...
Cholesterol and its transport
... -facilitate the solubilization of dietary lipids during the process of digestion by promoting micelle formation ...
... -facilitate the solubilization of dietary lipids during the process of digestion by promoting micelle formation ...
Quality control in tRNA charging — editing of homocysteine
... All living organisms conduct protein synthesis with a high degree of accuracy maintained in the transmission and flow of information from a gene to protein product. One crucial “quality control” point in maintaining a high level of accuracy is the selectivity by which aminoacyltRNA synthetases furni ...
... All living organisms conduct protein synthesis with a high degree of accuracy maintained in the transmission and flow of information from a gene to protein product. One crucial “quality control” point in maintaining a high level of accuracy is the selectivity by which aminoacyltRNA synthetases furni ...
Enzymes Enzymes are characterized by
... equation that relates the rate of catalysis (v) to the concentration of enzyme and substrate and the rates of the individual steps in the kinetic pathway: Starting point is that the rate at which ...
... equation that relates the rate of catalysis (v) to the concentration of enzyme and substrate and the rates of the individual steps in the kinetic pathway: Starting point is that the rate at which ...
Single-Amino Acid Substitutions Alter the Specificity and Affinity of
... nNOS (Figure 1C, R70A). However, R70A failed to bind Kv1.4. Thus, a single-amino acid substitution (Arg to Ala) confers nNOS binding on PDZ1 of PSD-95, but disrupts C-terminal peptide binding. These results suggest that an Arg or Lys residue in the carboxylate-binding loop of PDZ domains is required ...
... nNOS (Figure 1C, R70A). However, R70A failed to bind Kv1.4. Thus, a single-amino acid substitution (Arg to Ala) confers nNOS binding on PDZ1 of PSD-95, but disrupts C-terminal peptide binding. These results suggest that an Arg or Lys residue in the carboxylate-binding loop of PDZ domains is required ...
Structure-Function of the Glucagon Receptor Family of G Protein
... The glucagon-like peptides include glucagon, GLP-1, and GLP-2, and exert diverse actions on nutrient intake, gastrointestinal motility, islet hormone secretion, cell proliferation and apoptosis, nutrient absorption, and nutrient assimilation. GIP, a related member of the glucagon peptide superfamily ...
... The glucagon-like peptides include glucagon, GLP-1, and GLP-2, and exert diverse actions on nutrient intake, gastrointestinal motility, islet hormone secretion, cell proliferation and apoptosis, nutrient absorption, and nutrient assimilation. GIP, a related member of the glucagon peptide superfamily ...
Queuosine formation in eukaryotic tRNA occurs via a mitochondria
... into the NdeI and XhoI restriction sites of the pET21a plasmid (Novagen) to produce the plasmid Qv1:pET21a (His-tag). A truncated version of the mouse TGT (tTGT) was also produced, missing the coding sequence for the first 16 amino acids. This sequence was amplified from the fTGT:pGEX6P1 plasmid usi ...
... into the NdeI and XhoI restriction sites of the pET21a plasmid (Novagen) to produce the plasmid Qv1:pET21a (His-tag). A truncated version of the mouse TGT (tTGT) was also produced, missing the coding sequence for the first 16 amino acids. This sequence was amplified from the fTGT:pGEX6P1 plasmid usi ...
Enzymes
... Enzymes have extraordinary catalytic power, often far greater than that of synthetic or inorganic catalysts. They have a high degree of specificity for their substrates, they accelerate chemical reactions tremendously, and they function in aqueous solutions under very mild conditions of temperature ...
... Enzymes have extraordinary catalytic power, often far greater than that of synthetic or inorganic catalysts. They have a high degree of specificity for their substrates, they accelerate chemical reactions tremendously, and they function in aqueous solutions under very mild conditions of temperature ...
The Vitamin K-dependent Carboxylase*
... vertase that catalyzes the cleavage of the propeptide (73). The blood protein is then secreted and circulates in the blood as a zymogen. The importance of the removal of the pro sequence for the normal function of a VKD blood protein is exemplified by the identification of Hemophilia B patients that ...
... vertase that catalyzes the cleavage of the propeptide (73). The blood protein is then secreted and circulates in the blood as a zymogen. The importance of the removal of the pro sequence for the normal function of a VKD blood protein is exemplified by the identification of Hemophilia B patients that ...
Karbohidrat Metabolizması
... acetate - is not possible with TCA • Glyoxylate cycle offers a solution for plants and some bacteria and algae • The CO2-evolving steps are bypassed and an extra acetate is utilized • Isocitrate lyase and malate synthase are the short-circuiting enzymes ...
... acetate - is not possible with TCA • Glyoxylate cycle offers a solution for plants and some bacteria and algae • The CO2-evolving steps are bypassed and an extra acetate is utilized • Isocitrate lyase and malate synthase are the short-circuiting enzymes ...
Karbohidrat Metabolizması
... acetate - is not possible with TCA • Glyoxylate cycle offers a solution for plants and some bacteria and algae • The CO2-evolving steps are bypassed and an extra acetate is utilized • Isocitrate lyase and malate synthase are the short-circuiting enzymes ...
... acetate - is not possible with TCA • Glyoxylate cycle offers a solution for plants and some bacteria and algae • The CO2-evolving steps are bypassed and an extra acetate is utilized • Isocitrate lyase and malate synthase are the short-circuiting enzymes ...
Biochemical Oscillations
... Cooperative binding of ligands to a multisubunit enzyme is not limited to substrates. Other small molecules may bind to the enzyme and alter its catalytic properties (either its affinity for substrates or its rate of converting bound substrates into products). Such enzymes are called “allosteric” bec ...
... Cooperative binding of ligands to a multisubunit enzyme is not limited to substrates. Other small molecules may bind to the enzyme and alter its catalytic properties (either its affinity for substrates or its rate of converting bound substrates into products). Such enzymes are called “allosteric” bec ...
Rab Proteins and the Organization of Organelle Membrane Domains
... DOI 10.1007/978-3-319-07761-1_2, © Springer International Publishing Switzerland 2014 ...
... DOI 10.1007/978-3-319-07761-1_2, © Springer International Publishing Switzerland 2014 ...
Formate Dehydrogenase, Molecular Modeling and Docking with
... Swiss. As shown in Fig. 2, the Formate dehydrogenase from O. parapolymorpha DL-1 was modeled into dimer structure. As shown in Fig. 3A, the Ramachandran plot for FDH suggested 87.1%, 12.6%, 0.3% and 0.0% for residues in most favoured regions, additional allowed regions, generously allowed regions an ...
... Swiss. As shown in Fig. 2, the Formate dehydrogenase from O. parapolymorpha DL-1 was modeled into dimer structure. As shown in Fig. 3A, the Ramachandran plot for FDH suggested 87.1%, 12.6%, 0.3% and 0.0% for residues in most favoured regions, additional allowed regions, generously allowed regions an ...
Structure of the ordered hydration of amino acids
... and nitrogen) are considered, and by considering the side chain and main chain independently. This may lead to the overlooking of unconventional water–protein interactions and of the connection between the main chain and side chains. For example, the nitrogen heteroatoms of tryptophan and histidine ...
... and nitrogen) are considered, and by considering the side chain and main chain independently. This may lead to the overlooking of unconventional water–protein interactions and of the connection between the main chain and side chains. For example, the nitrogen heteroatoms of tryptophan and histidine ...
Carbohydrate metabolism
... •Facilitative diffusion by Na+-independent glucose transporter system (GLUT5). There are mobile carrier proteins responsible for transport of fructose, glucose, and galactose with their conc. gradient. •Active transport by sodium-dependent glucose transporter system (SGLUT1). In the intestinal cell ...
... •Facilitative diffusion by Na+-independent glucose transporter system (GLUT5). There are mobile carrier proteins responsible for transport of fructose, glucose, and galactose with their conc. gradient. •Active transport by sodium-dependent glucose transporter system (SGLUT1). In the intestinal cell ...
Transport proteins regulate the flux of metabolites and cofactors
... three carrier proteins for the uptake of the cofactors ATP and NAD into plant peroxisomes. The transport of the three substrates across the peroxisomal membrane is essential for the degradation of fatty acids and fatty acids-related compounds via β-oxidation. This metabolic pathway plays multiple fu ...
... three carrier proteins for the uptake of the cofactors ATP and NAD into plant peroxisomes. The transport of the three substrates across the peroxisomal membrane is essential for the degradation of fatty acids and fatty acids-related compounds via β-oxidation. This metabolic pathway plays multiple fu ...
University of Groningen Lactococcus lactis systems biology Eckhardt
... loss of industrial traits by failing to keep their plasmids, and are fighting acidification, starvation or temperature and/or salt shock 9,10. The principal mechanisms of stress resistance have been extensively studied in L. lactis 11–13. These studies have gained insight in the how L. lactis attemp ...
... loss of industrial traits by failing to keep their plasmids, and are fighting acidification, starvation or temperature and/or salt shock 9,10. The principal mechanisms of stress resistance have been extensively studied in L. lactis 11–13. These studies have gained insight in the how L. lactis attemp ...
No Slide Title
... Endotoxin moves from the gut into the bloodstream and the liver where it activates Kupffer cells- a type of immune cell (resident liver macrophages) - by interacting with CD14 causing nuclear factor kappa B (NFκB) production.This generates superoxide radicals (O2) and various signaling molecules (th ...
... Endotoxin moves from the gut into the bloodstream and the liver where it activates Kupffer cells- a type of immune cell (resident liver macrophages) - by interacting with CD14 causing nuclear factor kappa B (NFκB) production.This generates superoxide radicals (O2) and various signaling molecules (th ...
Purification and Characterization of a Novel Pumpkin Short
... on a PhastGel gradient of 10% to 15% following ion-exchange chromatography. Peak fractions (nos. 19–25) following a chromatography on a Mono-S column were subjected to SDS-PAGE and transferred onto a PVDF membrane. Approximately 1 L from each fraction was loaded per lane. Molecular mass marker posi ...
... on a PhastGel gradient of 10% to 15% following ion-exchange chromatography. Peak fractions (nos. 19–25) following a chromatography on a Mono-S column were subjected to SDS-PAGE and transferred onto a PVDF membrane. Approximately 1 L from each fraction was loaded per lane. Molecular mass marker posi ...
【金屬鍵】
... 14. In an experiment investigating the action of a kind of protease on protein, a glass tube of solid egg white was placed in each of the following labelled test tubes. Test tube A – with 4 cm3 of 1% protease Test tube B – with 4 cm3 of 1% protease and several drops of dilute hydrochloric acid Test ...
... 14. In an experiment investigating the action of a kind of protease on protein, a glass tube of solid egg white was placed in each of the following labelled test tubes. Test tube A – with 4 cm3 of 1% protease Test tube B – with 4 cm3 of 1% protease and several drops of dilute hydrochloric acid Test ...
Second Strasbourg Summer School on Chemoinformatics
... The tacrine/ acetylcholinesterase binding mode is difficult to predict, because: the size of the binding pocket largely exceeds the volume occupied by the ligand there is only one directional polar interaction between the ligand and the protein: the Hbond between the protonated pyridine of the p ...
... The tacrine/ acetylcholinesterase binding mode is difficult to predict, because: the size of the binding pocket largely exceeds the volume occupied by the ligand there is only one directional polar interaction between the ligand and the protein: the Hbond between the protonated pyridine of the p ...
PDF
... Grass pea has a high yielding potential (regarding a pea level) at a low fertilization level (Campbell et al., 1994; Patto et al., 2006). Currently, it is considered as a model crop for sustainable agriculture (Arslan, 2016; Patto et al., 2006). It is perhaps the most environmentally resistant legum ...
... Grass pea has a high yielding potential (regarding a pea level) at a low fertilization level (Campbell et al., 1994; Patto et al., 2006). Currently, it is considered as a model crop for sustainable agriculture (Arslan, 2016; Patto et al., 2006). It is perhaps the most environmentally resistant legum ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.