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On bioinformatics
On bioinformatics

... – molecular genetics • And Functional Protein Assays ...
Wanganui High School
Wanganui High School

... made of a sugar, a base and a phosphate group? ...
pdb-d.eng.uiowa.edu
pdb-d.eng.uiowa.edu

... The sequence of a gene may change much faster than the order of the genes May be a very useful confirmation or hint of the function of a gene ...
Recombinant DNA and gene cloning To use an unique feature(s) of
Recombinant DNA and gene cloning To use an unique feature(s) of

... To use an unique feature(s) of your gene/gene product to isolate the DNA fragment containing your gene from a library of DNA fragments. Difficulty in isolating genes (needle in a long line of connected needles): A gene is a small part of a large DNA (0.01% of an average chromosome); DNA pieces all h ...
DNA replication and PCR ppt
DNA replication and PCR ppt

... reference. The 5’ and 3’ hydroxyl groups (highlighted on the left) are used to attach phosphate groups. ...
DNA Timeline - WordPress.com
DNA Timeline - WordPress.com

... • Awarded the 1958 Nobel Prize for Physiology or Medicine ...
Genetic Engineering - University of Rhode Island
Genetic Engineering - University of Rhode Island

... enzymes that form a new chemical bond to join two molecules, and restriction enzymes, which can cut double-stranded DNA, can be very useful in the gene splicing process as well. The ability to modify DNA has great potential benefits. It could give humans the ability to cure disease, increase immunit ...
ACID BASE - Union City High School
ACID BASE - Union City High School

... A conjugate base is the particle that remains when an acid has donated a hydrogen ion. ...
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Genetic Engineering

... cases RNA, is the primary source of heritable information ...
One Step Quantitative Real-Time PCR Protocol
One Step Quantitative Real-Time PCR Protocol

... additional benefit of high-temperature reverse transcription, with a single enzyme for ease of use. The enzyme is recombinant Thermus thermophilus (rTth) thermostable DNA polymerase, which reverse transcribes RNA to cDNA in the presence of Mn2+ ion and polymerizes DNA during the PCR amplification. H ...
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SURVEY OF BIOCHEMISTRY

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DNA gel electrophoresis

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JF lect 5 12

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Using microsatellites as molecular markers
Using microsatellites as molecular markers

... Depending on number of microsatellite repeats, will get different lengths PCR products (many different possible alleles, not just two) ...
2.5 Genetics - Rocoscience
2.5 Genetics - Rocoscience

... (Matching) RNA production (notion of both DNA and RNA must be given) The process of making a protein using the mRNA code a template A haploid sex cell which is capable of fusion The fusion of 2[haploid] gametes to form a [diploid] zygote An alternative form of a gene Has identical alleles [for a tra ...
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Forensic Science Chapter 13

... 1. 2.1 (ch 13) Which of the following is NOT true of DNA? a. It is shaped like a long tubule dotted with ribosomes. b. Except in identical twins, it contains genetic information unique to each individual. c. It includes instructions to produce specific protein molecules. d. DNA typing had its beginn ...
Big Questions
Big Questions

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Pre-post test questions
Pre-post test questions

... 13. If an individual is a carrier for the autosomal recessive disease -thalassemia, what is their genotype and phenotype? Explain your reasoning. They will have one copy of the normal -hemoglobin gene and one copy with the mutation. They will have a normal phenotype because the normal copy of the ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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