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Difference between RNA and DNA
Difference between RNA and DNA

... 3. This can be VERY serious or it may make no difference at all! Why could it be serious? 4. What are some things that can cause a mutation in the DNA? Genetic Research. 1. Cloning: The process of making _____________ offspring from the cells of an organism. This is used in: 2. Genetic Engineering: ...
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AP Biology DNA Technology: The manipulation of organisms or their

... o Smaller segments migrate further than large ones. o Every individual has a unique set of fragment lengths because of polymorphisms (slight differences in DNA sequences)  These fragments are called restriction fragment length polymorphisms or RFLP’s.  In DNA fingerprinting, RFLP’s are compared, i ...
Mutations (1 of 2)
Mutations (1 of 2)

... substitution in the beta-hemoglobin gene, which alters a single amino acid in the protein produced. 2. change a codon to one that encodes the same amino acid and causes no change in the protein produced. These are called silent mutations. 3. change an amino-acid-coding codon to a single “stop” codon ...
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PowerPoint Slides

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DNA TECHNOLOGY - Mount Mansfield Union High School

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Chapter 15 - Translation of mRNA

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Biology 1 Unit 2 2. Chemistry: Atoms, Compounds, Water, pH

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Analysis of in-vivo LacR-mediated Gene Repression Based on the

... The DNA helical axes in the LacR cocrystal structure with operator DNA do not lie in the mean plane of the tetramer subunits (Figure 1B), but instead are separated by a dihedral angle of about 20 degrees [1]. This implies that the crystallographic structure should introduce some writhe into a LacR-m ...
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Archaebacterial virus SSV1 encodes a putative DnaA

... In a previous study (1) we have shown that proteins containing the purine NTP-binding sequence pattern (2) and involved in genome replication or DNA precursor synthesis are extremely wide-spread products of the genomes of various viruses. In particular, all viruses with double-stranded (ds) DNA geno ...
Teacher quality grant - Gulf Coast State College
Teacher quality grant - Gulf Coast State College

... - PCR impacted several areas of genetic research: - as a medical diagnostic tool to detect specific mutations that may cause genetic disease - in criminal investigations and courts of law to identify suspects - in the sequencing of the human genome ...
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... o rRNA (where “r” = “ribosomal”) associates with ribosomal proteins to form the ribosome. A nucleotide triplet (e.g., AGA) in mRNA is called a codon. Each codon encodes one amino acid (except for stop codons, which do not encode amino acids). Codons are read consecutively on mRNA from 5’ to 3’. The ...
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Teacher quality grant

... - PCR impacted several areas of genetic research: - as a medical diagnostic tool to detect specific mutations that may cause genetic disease - in criminal investigations and courts of law to identify suspects - in the sequencing of the human genome ...
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DNA Probes

... duplex of DNA. 2. Clones containing a particular gene, or DNA sequence, can be identified in a clone library by using the process of hybridization and labeled DNA probes. 3. DNA probes from "natural" and "artificial" sources can be used but both rely on the formation of DNA-DNA hybridization to make ...
Ch.05The Structure and Function of Large Biological Molecules
Ch.05The Structure and Function of Large Biological Molecules

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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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