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Ch. 13.4: DNA Applications
Ch. 13.4: DNA Applications

... a. How are plasmids useful to bacteria? b. How are plasmids useful to humans? 3. How is a recombinant DNA plasmid made and how are recombinant plasmids used to clone genes? Summarize the process. (Recombinant insulin plasmid) a. What is the role of restriction enzyme?  What natural role do they pla ...
6.4 RNA - Part 2 - Translation rna_2_s12
6.4 RNA - Part 2 - Translation rna_2_s12

26.9 Purines ond pyrimidines ,,,,,f sr`-c
26.9 Purines ond pyrimidines ,,,,,f sr`-c

... Organisms need to synthesizepurine and pyrimidine basesfor incorporation into the nucleic acids RNA and DNA. Moreover, nucleosides such as adenosine are found as part of ATB cyclic AMf; CoA (coenzymeA), NAD+ (nicotinamide adenine dinucleotide), and FAD (flavin adenine dinucleotide). The atoms that c ...
chapter 19 addendum
chapter 19 addendum

... Treat this with mild acid, and the first amino acid is cleaved off, rearranging to form a phenylthiohydantoin. This can be compared to a standard, and the amino acid identified. Each amino acid is removed from the N terminus and identified this way… and the process is automated on a ...
1. A brief overview of sequencing biochemistry
1. A brief overview of sequencing biochemistry

Genetic_Engineering_part_2[1]
Genetic_Engineering_part_2[1]

... • The gene, as well as the name come from a soil bacterium, Bacillus thuringiensis, which has the ability to produce a protein that is fatal to the larvae of certain crop-eating pests. ...
Chapter 19: Recombinant DNA Technology
Chapter 19: Recombinant DNA Technology

... variety of techniques and procedures to manipulate DNA and unlock the secrets of gene action. The first step for most scientists is to produce large numbers of copies of the gene of interest. This process is called cloning. While the term cloning is now typically associated with organismal cloning, ...
Accelerated nucleic acid purification
Accelerated nucleic acid purification

... Tecan Group Ltd. makes every effort to include accurate and up-to-date information within this video or animation; however, it is possible that omissions or errors might have occurred. Tecan Group Ltd. cannot, therefore, make any representations or warranties, expressed or implied, as to the accurac ...
Final Exam
Final Exam

... 10. Two pea plants are both heterozygous for the dominant traits of tall height and purple flowers. (short height and white flowers are recessive) What is the probability that a cross of these two plants will produce a white flowered, short plant? ...
Lecture 15 Genetic Regulation
Lecture 15 Genetic Regulation

... A Role for Minerals in Genetic Expression Summary: Metal ions are not passive components of biological systems as once thought. Recent studies have shown that Fe, Cu, or Zn are capable of regulating the expression of genes that code for that metal’s storage or transport proteins ...
Horak - Blumberg Lab
Horak - Blumberg Lab

... February 16, 2017 ...
Patterns of Inheritance 10 Grade - Delaware Department of Education
Patterns of Inheritance 10 Grade - Delaware Department of Education

... a. Circle the specific mutations in the DNA sequence (Figure 1) that is responsible for Sarah’s disorder. b. Identify the autosomal pattern of inheritance in which Tay Sachs is passed from one generation to the next using the evidence in Figures 1 and 2. ...
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Slide 1

... • Removed the viruses and just looked at the bacterial cells to see which ones had radioactivity – Bacteria that were exposed to viruses with radioactive DNA had radioactivity – Bacteria that were exposed to viruses with radioactive protein did not have radioactivity ...
The Goldstein family is of Ashkenazi Jewish descent
The Goldstein family is of Ashkenazi Jewish descent

... a. Circle the specific mutations in the DNA sequence (Figure 1) that is responsible for Sarah’s disorder. b. Identify the autosomal pattern of inheritance in which Tay Sachs is passed from one generation to the next using the evidence in Figures 1 and 2. ...
ppt - Language Log
ppt - Language Log

... complicated, for our purposes, we can examine the major function: that of the synthesis of proteins. • Proteins are a very large class of molecules which perform a huge array of functions in living things. It has been estimated that there are over 60,000 different proteins in the human body, only ab ...
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Proteins We now know about the building blocks of proteins (amino

MAKEUP: Briefly discuss functions of the liver
MAKEUP: Briefly discuss functions of the liver

... o Protein synthesis  Lipoproteins - Catabolic Functions: o CHO: Glycogenolysis, gluconeogenesis (via acetyl CoA formation from fatty acid breakdown) → maintain BSL o Fats: ↑lipolysis  Ketone body formation  Bile Acid formation (for fat absorption) o Proteins  Ammonium formation (via glutathione ...
Genetic Changes Chapter 11.3
Genetic Changes Chapter 11.3

... gene works, which may in turn cause changes in an animal's appearance, or behavior . Sometimes, a new gene variant may mean the animal is better adapted to its surroundings, improving its chances of survival. So this animal is more likely to have offspring, which will inherit the beneficial ...
Lecture 2
Lecture 2

... → transports RNA data to the ribosome for protein synthesis ...
Bioinformatics in Computer Sciences at NJIT
Bioinformatics in Computer Sciences at NJIT

... consisting of four letters: A, C, G, and T. They could be very long, e.g. thousands and even millions of letters • Proteins are also represented as strings of 20 letters (each letter is an amino acid). Their 3-D structure determines the function to a large extent. ...
BIO305 - National Open University of Nigeria
BIO305 - National Open University of Nigeria

... have a number of experimental advantages similar to those of E. coli and have provided a model for studies of many aspects of eukaryotic cell biology. The genome of the most studied yeasts, Saccharomyces cervisae, consists of 12 million base pairs of DNA and contains about 6000 genes; and is about ...
Positive Strand RNA Viruses
Positive Strand RNA Viruses

Chapter 9
Chapter 9

... maternally derived chromosome 15, a completely different disease, Angelman syndrome, arises. This pattern of inheritance when expression of a gene depends on whether it is inherited from the mother or the father is called genomic imprinting. The mechanism of imprinting is uncertain, but, it may invo ...
Holliday Poster - The HeliX group
Holliday Poster - The HeliX group

... Competitive dialysis or competition dialysis was initially described by Ren and Chaires1 and has since then been adapted in this laboratory. The aim of such an experiment is to determine which sequence a drug preferentially binds to in ...
in Power-Point Format
in Power-Point Format

... • Mutations if cell attempts to replicate without repair – Others change base-pairing properties, so are mutagenic: • Ethyl O6-G mispairs with T -> GC ->AT transition mutation ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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