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The enhancement of ribosomal transcription by the recycling of RNA
The enhancement of ribosomal transcription by the recycling of RNA

... these promoters is not always detected (6). Transcription of the 3'-ETS may have the further effect of sweeping transcription factors bound by the 60/81 b.p. elements, towards the pre-rRNA promoter, (1). Readthrough Enhancement would further increase the efficiency with which transcription factors w ...
Amino Acids, Peptides, and Proteins
Amino Acids, Peptides, and Proteins

... from less common amino acids that are residues modified after a protein has been synthesized, and from the many other kinds of amino acids present in living organisms but not in proteins. The standard amino acids have been assigned three-letter abbreviations and one-letter symbols (Table 5–1, p. 118 ...
Catalytic mechanism of nucleoside diphosphate kinase investigated
Catalytic mechanism of nucleoside diphosphate kinase investigated

... excess of ATP. To simplify the separation, ADP generated in the reaction was converted to ATP with a creatine phosphate/creatine phosphokinase regenerating system. After purification on QAE-Sephadex A25 at pH 8.0, phosphorylation to the diphosphate was performed with thymidylate kinase, in the prese ...
Cloning and Expression of Bovine Sodium/Glucose Cotransporters* J. Dairy Sci. 88:182–194
Cloning and Expression of Bovine Sodium/Glucose Cotransporters* J. Dairy Sci. 88:182–194

... study indicate that the different sizes of these transcripts ...
AMINO ACIDS, PEPTIDES, AND PROTEINS
AMINO ACIDS, PEPTIDES, AND PROTEINS

Acid-Base Biochemistry
Acid-Base Biochemistry

... very similar to the Arrhenius definition, any substance that can donate a hydrogen ion is an acid (under the Brønsted definition, acids are often referred to as proton donors because an H+ ion, hydrogen minus its electron, is simply a proton). ...
Organic Chemistry/Fourth Edition: e-Text
Organic Chemistry/Fourth Edition: e-Text

... Conversion of Acyl Chlorides to Other Carboxylic Acid Derivatives General equation and specific example ...
The Role of Different Sugars, Amino Acids and Few Other
The Role of Different Sugars, Amino Acids and Few Other

... the relevant cell numbers were above, below or equal to zero respectively. Statistical analyses The significance of differences between the mean results obtained from different chemical substances and PBS as control were analyzed by one sample t-test. For most cases P< 0.05 was considered statistica ...
Pineapple Juice and Its Fractions in Enzymatic Browning Inhibition
Pineapple Juice and Its Fractions in Enzymatic Browning Inhibition

... Malic and citric acid contents were determined and reported as g total acids/100 mL. For sugar analysis, the HPLC system consisted of a 4100 LDO pump and a RI 4 LDC detector. The column used was ZorbaxNH2 (250 mm × 4.6 mm id). Isocratic elution with 82% (v/v) acetonitrile in water was used at a flow ...
Role of the p21 Protein in the Fanconi Anemia Pathway
Role of the p21 Protein in the Fanconi Anemia Pathway

... • Treat HCT116 p21+/+ and HCT116 p21-/- cells with the DNAcrosslinking agent mitomycin C (MMC). • Allow cells to grow for about 10 days. • Stain with crystal violet to quantify cells that survived. • Observe whether cells lacking p21 (HCT116 p21-/-) are more sensitive to MMC than wild type cells (HC ...
Amino Acids, Proteins, and Enzymes
Amino Acids, Proteins, and Enzymes

What`s new - JSI medical systems
What`s new - JSI medical systems

... The entry in Suffix can have up to six characters. The suffix is added to the Name of the ROI, e.g: Suffix ng (for NimbleGene), ROI name is BRCA1E01-ng. Therefore all ROIs added on tab Enrichment have a suffix in the ROI name listed in column Name. There is the setting auto cut available: If you use ...
Natural Computing - Computer Science
Natural Computing - Computer Science

... Uses biomolecules, e.g., DNA, RNA • Quantum Computing Uses, e.g., ion traps, superconductors, nuclear magnetic resonance ...
Biochemistry 304 2014 Student Edition Amino Acid Metabolism
Biochemistry 304 2014 Student Edition Amino Acid Metabolism

... Do NOT memorize any of the specific amino acid catabolic or anabolic pathways. They are for informational purposes only. ...
Rabbit genome editing with zinc finger nucleases
Rabbit genome editing with zinc finger nucleases

... disease-related protein results in the disease in the rabbit. In other embodiments, the edited chromosomal sequence encoding a disease- or trait-related protein comprises at least one modi?cation such that the altered version of the protein protects against a disease or does not form a trait in the ...
Pharmacogenomics: Analyzing SNPs in the CYP2D6 Gene Using
Pharmacogenomics: Analyzing SNPs in the CYP2D6 Gene Using

... cysteine and four of them code for arginine at the SNP #5 site. We suggest that the arginine is the detrimental SNP. The two which code for cysteine (CYP2D6*17 and CYP2D6*17V) contain one other SNP with multiple radical changes in amino acid properties and CYP2D6*4A, CYP2D6*4D, and CYP2D6*10B also c ...
Synthetic Chemical Inducers and Genetic
Synthetic Chemical Inducers and Genetic

... Figure 4. Design and evaluation of improved, rhaS-encoding reporter plasmid, pCK302. (a) Design of pCK302. It was hypothesized that weak induction of PrhaBAD resulted from poor rhaS expression, which in turn was due to suboptimum interaction of candidate inducers with RhaR. A new reporter plasmid, p ...
H - IS MU
H - IS MU

... 2 Carnitine carries long-chain activated fatty acids into the mitochondrial matrix Acyl-CoA itself cannot cross the inner mitochondrial membrane; instead, acyl groups are transferred to carnitine, transported across the membrane as acylcarnitine, and transferred back to CoA within the mitochondrial ...
BIOLOGY BIOLOGY - HCC Learning Web
BIOLOGY BIOLOGY - HCC Learning Web

... © 2014 Pearson Education, Inc. ...
Sculpting the b-peptide foldamer H12 helix via a designed side
Sculpting the b-peptide foldamer H12 helix via a designed side

... feature of the helix formation. Foldamers 2 and 3 display higher intensities at short wavelengths, which might indicate a partial population of an elongated structure such as H8 helix.16 Experimental17 and theoretical18 studies and our own earlier results19 indicate that self-association in the solu ...
PROPERTIES OF CARBOXYLIC ACIDS
PROPERTIES OF CARBOXYLIC ACIDS

... Ball-and-stick model of ethyne molecule ...
CoA
CoA

... 2. Malic enzyme and acetyl CoA carboxylase 3. For fatty acid synthase: a) substrates/key products; b) sources of NADPH; c) general mechanism 4. Relationship: regulation of carnitine-palmitoyl transferase-I and preventing oxidation of synthesized palmitoyl CoA ...
URIC ACID
URIC ACID

... Nucleotide degradation involves the formation of the respective nucleosides (inosine, adenosine and guanosine) (NUCLEOSIDES: purine base + sugar), these are subsequently metabolised to the respective purine bases (hypoxanthine, adenine and guanine) (PURINE BASES). Hypoxanthine and guanine can be met ...
High-resolution melting analysis of the single nucleotide
High-resolution melting analysis of the single nucleotide

lecture7
lecture7

... The intermediates in fatty acid synthesis are linked to an acyl carrier protein. Specifically, they are linked to the sulfhydryl terminus of a phosphopantetheine group, which is, in turn, attached to a serine residue of the acyl carrier protein (Figure 22.21). Recall that, in the degradation of fatt ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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