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BP DB (Recovered) - Base Pair Biotechnologies
BP DB (Recovered) - Base Pair Biotechnologies

... Base Pair Biotechnologies provides custom aptamer development services and catalog aptamers to academic, commercial, and government researchers for a variety of applications. To support their efforts we provide this series of aptamer best practices as a introduction to their use. Additional assistan ...
Short Communication Highly sensitive detection of cancer cells
Short Communication Highly sensitive detection of cancer cells

... covering the monoclonal antibody on the surface of the streptavidin coated magnetic particles. To prepare anti-EpCAM MMPs, monoclonal EpCAM antibodies were first biotinylated using a biotinylation kit according to manufacturer’s protocol. Then, the biotinylated monoclonal antibodies were linked to t ...
C14, C14:1
C14, C14:1

... 2. Patients with disorders known to pose risk but reduced penetrance  ie. probably not everyone needs to be treated  HPHE, MCAD  Both are/have mild ends of the spectrum that have only been identified through NBS  MCAD mutation c.199 C>T ...
chromatographic analysis of organic acids, amino acids, and sugars
chromatographic analysis of organic acids, amino acids, and sugars

... acids were prevailing in Ocimum americanum herb (Table 1); similar results were observed in Ocimum tenuiflorum and Calamintha officinalis herb (Lamiaceae) (18, 19). Importantly, some fatty acids in Ocimum sanctum seed possess the anti-inflammatory activity (20). Several water-soluble carbohydrates i ...
Expanding and understanding the genetic toolbox of the
Expanding and understanding the genetic toolbox of the

... tool to investigate the role and function of genes. In model organisms from all three domains of life, methods have been developed to integrate engineered DNA site-specifically into the genome. These techniques rely mainly on homologous recombination and allow new genes to be introduced into a genom ...
Amino Acid Profiling and Nucleic Acid
Amino Acid Profiling and Nucleic Acid

... produced the highest overall yields (0.113-1.659 g essential amino acid/100 g of SCP). Those obtained via ethanol precipitation on the other hand did not contain valine or methionine. Keywords: Single cell protein (SCP), nucleic acid and essential amino acids ...
Chapter 20 Regulation of Gene Expression in Eukaryotes
Chapter 20 Regulation of Gene Expression in Eukaryotes

Brief Introduction of Patent Prosecution Issues in Biotech Field
Brief Introduction of Patent Prosecution Issues in Biotech Field

... Claim: A nucleic acid (polypeptide) comprising a nucleotide (amino acid) sequence as set forth in SEQ ID NO:1. Rejection: “comprising” lacks support because additional nucleotides (amino acids) added to any of the terminals of SEQ ID NO:1 will change the activity of the nucleic acid (polypeptide) wi ...
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Explain advantages of Carbohydrates Lipids Proteins

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science - Sarah Mahajan Study Guides

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Various University Examination Questions on Fatty acid

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(a) A(1) - at www.arxiv.org.
(a) A(1) - at www.arxiv.org.

... genetic code in UCGA succession shows an almost linear correlation between amino acid property and sp2 N-numbers.5 We suggested a possible primordial core in the genetic code on the basis of two pieces of evidence.5 First, accompanied with a linear correlation between the hydropathy of amino acids a ...
Breast Cancer
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... called Short Tandem Repeats (abbreviated STRs and also called microsatellites). An STR is a region of DNA composed of a short sequence of nucleotides repeated many times. The number of repeated sequences in a given STR varies from person to person. The alternate forms of a given STR correspond with ...
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Ribosomal DNA sequences reveal gregarine pathogens

SPARK™ DNA Sample Prep Kit Illumina® Platform
SPARK™ DNA Sample Prep Kit Illumina® Platform

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1- All of the following amino acids are neutral except

... II) Complete the following sentences:1- Acidic proteins are ……………………………………… & ………………………………………………… 2- Indol group in ……………………….. amino acid is detected by ……………………………… test 3- Bonds of stabilizing β pleated sheets are ……………………..……. & ………………….…………… 4- Essential aromatic amino acids are ……………………………… & ...
Chapter 5
Chapter 5

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18.1 Studying Viruses and Prokaryotes
18.1 Studying Viruses and Prokaryotes

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Chapter Four - people.iup.edu
Chapter Four - people.iup.edu

... • Many genes encoding enzymes of a single biochemical pathway are clustered into groups called operons • Operons are equally distributed on both strands • ~5 Mbp in size (entire chromosome) • ~40% of predicted proteins are of unknown function • Average protein contains ~300 amino acids • Genes are c ...
Q repeat 9 interval amino acid forms in man and pathogen
Q repeat 9 interval amino acid forms in man and pathogen

... lesser and greater lengths, I find it compelling that the 11 region assay is found among man’s critical tissues of brain stem, bone marrow and hepatic sites...with amino characters and the repeats among the pathogens that mirror length. Exploring this issue among the like regions of Homo sapiens and ...
Proteins - Clayton State University
Proteins - Clayton State University

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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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