Fortaz - GlaxoSmithKline
... Elderly Patients Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. ...
... Elderly Patients Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. ...
PhD thesis
... their effect on the sex steroid hormone balance in more complex test systems. The H295R cell line assay, an established assay developed to identify compounds that can disrupt steroidogenesis was used to evaluate the two SSRIs sertraline and fluvoxamine. Male rats were ...
... their effect on the sex steroid hormone balance in more complex test systems. The H295R cell line assay, an established assay developed to identify compounds that can disrupt steroidogenesis was used to evaluate the two SSRIs sertraline and fluvoxamine. Male rats were ...
Diltiazem Hydrochloride Extended-Release Capsules, USP
... during coadministration, and should be based on clinical assessment. Carbamazepine Concomitant administration of diltiazem with carbamazepine has been reported to result in elevated serum levels of carbamazepine (40% to 72% increase), resulting in toxicity in some cases. Patients receiving these dru ...
... during coadministration, and should be based on clinical assessment. Carbamazepine Concomitant administration of diltiazem with carbamazepine has been reported to result in elevated serum levels of carbamazepine (40% to 72% increase), resulting in toxicity in some cases. Patients receiving these dru ...
Lopinavir/ritonavir combined with twice
... lopinavir penetrates poorly into the CSF and semen;8,13 interestingly, two patients had lopinavir concentrations in CSF of 27 and 29 ng/mL, which are above both the limits of detection (10 ng/mL) and the non-protein-corrected EC50 of lopinavir, after the addition of indinavir. Together with the upwa ...
... lopinavir penetrates poorly into the CSF and semen;8,13 interestingly, two patients had lopinavir concentrations in CSF of 27 and 29 ng/mL, which are above both the limits of detection (10 ng/mL) and the non-protein-corrected EC50 of lopinavir, after the addition of indinavir. Together with the upwa ...
Sacubitril / Valsartan salt complex
... aldosterone. ACE inhibitors block the deleterious effects of angiotensin II and, usually combined with a diuretic, they have formed the basis of treatment for many years. Additional complementary therapies include beta-blockers and aldosterone antagonists (MRAs). ACEIs are recommended as first-line ...
... aldosterone. ACE inhibitors block the deleterious effects of angiotensin II and, usually combined with a diuretic, they have formed the basis of treatment for many years. Additional complementary therapies include beta-blockers and aldosterone antagonists (MRAs). ACEIs are recommended as first-line ...
Influence of Vesicle Size, Lipid Composition, and
... the dark and then centrifuged at 15,000 x g for 30 min. The supernawhere needed with sterile saline to achieve a total lipid concentration tants were analyzed for doxorubicin and its fluorescent metabolites by of 100 mg/ml. This step was necessary to avoid death on injection monitoring the fluoresce ...
... the dark and then centrifuged at 15,000 x g for 30 min. The supernawhere needed with sterile saline to achieve a total lipid concentration tants were analyzed for doxorubicin and its fluorescent metabolites by of 100 mg/ml. This step was necessary to avoid death on injection monitoring the fluoresce ...
Product Monograph ZANTAC
... Sporadic cases of drug interactions have been reported in elderly patients involving both hypoglycaemic drugs and theophylline. The significance of these reports cannot be determined at present, as controlled clinical trials with theophylline and ZANTAC® have not shown interaction. If high doses (tw ...
... Sporadic cases of drug interactions have been reported in elderly patients involving both hypoglycaemic drugs and theophylline. The significance of these reports cannot be determined at present, as controlled clinical trials with theophylline and ZANTAC® have not shown interaction. If high doses (tw ...
Reyataz - Products - Bristol
... ------------------------------INDICATIONS AND USAGE-----------------------------REYATAZ is a protease inhibitor indicated for use in combination with other antiretroviral agents for the treatment of HIV-1 infection for patients 3 months and older weighing at least 5 kg. (1) ------------------------- ...
... ------------------------------INDICATIONS AND USAGE-----------------------------REYATAZ is a protease inhibitor indicated for use in combination with other antiretroviral agents for the treatment of HIV-1 infection for patients 3 months and older weighing at least 5 kg. (1) ------------------------- ...
XOPENEX®(levalbuterol HCI)
... patients 6-11 years old is 0.31 mg administered three times a day, by nebulization. Routine dosing should not exceed 0.63 mg three times a day. Adults and Adolescents ≥12 years old: The recommended starting dosage of XOPENEX Inhalation Solution for patients 12 years of age and older is 0.63 mg admin ...
... patients 6-11 years old is 0.31 mg administered three times a day, by nebulization. Routine dosing should not exceed 0.63 mg three times a day. Adults and Adolescents ≥12 years old: The recommended starting dosage of XOPENEX Inhalation Solution for patients 12 years of age and older is 0.63 mg admin ...
Product Monograph
... management strategies, and other information relevant to the use of the drug. ...
... management strategies, and other information relevant to the use of the drug. ...
product monograph isoptin sr
... Verapamil hydrochloride does not alter total serum calcium levels. However, one report suggested that calcium levels above the normal range may decrease the therapeutic effect of verapamil hydrochloride. Carcinogenesis and Mutagenesis There was no evidence of a carcinogenic effect when verapamil hy ...
... Verapamil hydrochloride does not alter total serum calcium levels. However, one report suggested that calcium levels above the normal range may decrease the therapeutic effect of verapamil hydrochloride. Carcinogenesis and Mutagenesis There was no evidence of a carcinogenic effect when verapamil hy ...
risperdal consta
... higher dose of 37.5 mg or 50 mg. The maximum dose should not exceed 50 mg RISPERDAL CONSTA® every 2 weeks. No additional benefit was observed with dosages greater than 50 mg RISPERDAL CONSTA®; however, a higher incidence of adverse effects was observed. The efficacy of RISPERDAL CONSTA® in the tr ...
... higher dose of 37.5 mg or 50 mg. The maximum dose should not exceed 50 mg RISPERDAL CONSTA® every 2 weeks. No additional benefit was observed with dosages greater than 50 mg RISPERDAL CONSTA®; however, a higher incidence of adverse effects was observed. The efficacy of RISPERDAL CONSTA® in the tr ...
Theracurmin | Information Sheet
... for Theracurmin was 29.5 ng/ml, compared to 1.8 ng/ml for standard curcumin. Theracurmin reached Tmax in one hour, compared to six hours for standard curcumin. Following this study, it remained to be determined whether higher doses of Theracurmin could increase plasma curcumin levels in a dose-depen ...
... for Theracurmin was 29.5 ng/ml, compared to 1.8 ng/ml for standard curcumin. Theracurmin reached Tmax in one hour, compared to six hours for standard curcumin. Following this study, it remained to be determined whether higher doses of Theracurmin could increase plasma curcumin levels in a dose-depen ...
TASTE MASKED CHEWABLE DISPERSIBLE TABLET OF ATOMOXETINE HYDROCHLORIDE Research Article HUDA.I.G*
... drugs have a natural bitter taste that can create a burning feeling in the throat or in the mouth. In particular, a bitter taste can decrease the patient compliance and thus reducing an effective pharmacotherapy. In order to achieve an acceptable palatability, the addition of flavors or sweeteners i ...
... drugs have a natural bitter taste that can create a burning feeling in the throat or in the mouth. In particular, a bitter taste can decrease the patient compliance and thus reducing an effective pharmacotherapy. In order to achieve an acceptable palatability, the addition of flavors or sweeteners i ...
Optimal dosing strategies for maximising the clinical response to
... patients with type 2 diabetes20 and more than 60% of patients in this study switched to metformin-glibenclamide combinations went on to achieve FPG ≤ 6.7 mmol/L. A further study compared the effects on glycaemia of escalating doses of metformin in nine patients with type 2 diabetes.16 The metformin ...
... patients with type 2 diabetes20 and more than 60% of patients in this study switched to metformin-glibenclamide combinations went on to achieve FPG ≤ 6.7 mmol/L. A further study compared the effects on glycaemia of escalating doses of metformin in nine patients with type 2 diabetes.16 The metformin ...
Unauthorized Research on Cluster Headache
... changed the life of a million sufferers,” wrote Donald Price (Puca 2003). ...
... changed the life of a million sufferers,” wrote Donald Price (Puca 2003). ...
Paritaprevir / Ritonavir / Ombitasvir and Dasabuvir
... An Australian Public Assessment Report (AusPAR) provides information about the evaluation of a prescription medicine and the considerations that led the TGA to approve or not approve a prescription medicine submission. ...
... An Australian Public Assessment Report (AusPAR) provides information about the evaluation of a prescription medicine and the considerations that led the TGA to approve or not approve a prescription medicine submission. ...
Dextromethorphan abuse: Clinical effects
... Since the introduction of DM in the 1950s, several cycles of abuse have been reported beginning with the withdrawal of Romilar. In 1986, the Swedish National Board of Health and Welfare moved DM into prescription status following reports of abuse-related deaths in two teenagers.4 More recently, the ...
... Since the introduction of DM in the 1950s, several cycles of abuse have been reported beginning with the withdrawal of Romilar. In 1986, the Swedish National Board of Health and Welfare moved DM into prescription status following reports of abuse-related deaths in two teenagers.4 More recently, the ...
Updated European Heart Rhythm Association Practical Guide on the
... Non-valvular AF refers to AF that occurs in the absence of mechanical prosthetic heart valves and in the absence of moderate to severe mitral stenosis (usually of rheumatic origin) (Table 1). Both types of patients were excluded from all NOAC trials. Atrial fibrillation in patients with other valvul ...
... Non-valvular AF refers to AF that occurs in the absence of mechanical prosthetic heart valves and in the absence of moderate to severe mitral stenosis (usually of rheumatic origin) (Table 1). Both types of patients were excluded from all NOAC trials. Atrial fibrillation in patients with other valvul ...
Effect of Caffeine on the Ventilatory Response to CO2 in
... laboratory was used in conjunction with a body plethysmograph to study the respiratory effects of caffeine and CO2 in 4- to 6-day-old rats. From each recording, VT, f, minute ventilation (VE), time of inspiration (Ti), and total time of each breath (Ttot) were obtained, and effective timing (Ti/Ttot ...
... laboratory was used in conjunction with a body plethysmograph to study the respiratory effects of caffeine and CO2 in 4- to 6-day-old rats. From each recording, VT, f, minute ventilation (VE), time of inspiration (Ti), and total time of each breath (Ttot) were obtained, and effective timing (Ti/Ttot ...
Updated European Heart Rhythm Association - prof
... Non-valvular AF refers to AF that occurs in the absence of mechanical prosthetic heart valves and in the absence of moderate to severe mitral stenosis (usually of rheumatic origin) (Table 1). Both types of patients were excluded from all NOAC trials. Atrial fibrillation in patients with other valvul ...
... Non-valvular AF refers to AF that occurs in the absence of mechanical prosthetic heart valves and in the absence of moderate to severe mitral stenosis (usually of rheumatic origin) (Table 1). Both types of patients were excluded from all NOAC trials. Atrial fibrillation in patients with other valvul ...
Updated European Heart Rhythm Association
... Non-valvular AF refers to AF that occurs in the absence of mechanical prosthetic heart valves and in the absence of moderate to severe mitral stenosis (usually of rheumatic origin) (Table 1). Both types of patients were excluded from all NOAC trials. Atrial fibrillation in patients with other valvul ...
... Non-valvular AF refers to AF that occurs in the absence of mechanical prosthetic heart valves and in the absence of moderate to severe mitral stenosis (usually of rheumatic origin) (Table 1). Both types of patients were excluded from all NOAC trials. Atrial fibrillation in patients with other valvul ...
PRODUCT MONOGRAPH PrCELEBREX ® (celecoxib) Capsules
... Blood dyscrasias: Blood dyscrasias (such as neutropenia, leukopenia, thrombocytopenia, aplastic anemia and agranulocytosis) associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) are rare, but could occur with severe consequences. Anemia is sometimes seen in patients receiving NSAI ...
... Blood dyscrasias: Blood dyscrasias (such as neutropenia, leukopenia, thrombocytopenia, aplastic anemia and agranulocytosis) associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) are rare, but could occur with severe consequences. Anemia is sometimes seen in patients receiving NSAI ...
Updated European Heart Rhythm Association Practical
... Non-valvular AF refers to AF that occurs in the absence of mechanical prosthetic heart valves and in the absence of moderate to severe mitral stenosis (usually of rheumatic origin) (Table 1). Both types of patients were excluded from all NOAC trials. Atrial fibrillation in patients with other valvul ...
... Non-valvular AF refers to AF that occurs in the absence of mechanical prosthetic heart valves and in the absence of moderate to severe mitral stenosis (usually of rheumatic origin) (Table 1). Both types of patients were excluded from all NOAC trials. Atrial fibrillation in patients with other valvul ...
BayeraspirinHCP.com
... Aspirin is a more potent inhibitor of platelet aggregation than other salicylic acid derivatives. Aspirin affects platelet aggregation by irreversibly inhibiting prostaglandin cyclo-oxygenase-1 (COX-1). This effect lasts for the life of the platelet and prevents the formation of the platelet aggrega ...
... Aspirin is a more potent inhibitor of platelet aggregation than other salicylic acid derivatives. Aspirin affects platelet aggregation by irreversibly inhibiting prostaglandin cyclo-oxygenase-1 (COX-1). This effect lasts for the life of the platelet and prevents the formation of the platelet aggrega ...