Toxicity of Nutmeg (Myristicin): A Review
... ingested nutmeg dose may have been between 560 and 840 mg/kg (39-59 g per 70 kg). The second case As of now in literature, only two nutmeg-associated fatalities have been described. The first, reported in 1887, describes an 8 year old boy who reportedly ingested two nutmegs and was found semi-comato ...
... ingested nutmeg dose may have been between 560 and 840 mg/kg (39-59 g per 70 kg). The second case As of now in literature, only two nutmeg-associated fatalities have been described. The first, reported in 1887, describes an 8 year old boy who reportedly ingested two nutmegs and was found semi-comato ...
38: Opioids
... segments, an amino terminus, and a carboxy terminus. Significant sequence homology exists between the transmembrane regions of opioid receptors and those of other members of the guanosine triphosphate (GTP)– binding protein (G-protein)–binding receptor superfamily. However, the extracellular and int ...
... segments, an amino terminus, and a carboxy terminus. Significant sequence homology exists between the transmembrane regions of opioid receptors and those of other members of the guanosine triphosphate (GTP)– binding protein (G-protein)–binding receptor superfamily. However, the extracellular and int ...
FLUOROQUINOLONES - American Academy of Veterinary
... Federal law prohibits the extralabel use of fluoroquinolones in food-producing animals (21 CFR 530.41). The prohibition is based on a finding by the Food and Drug Administration (FDA) that the extralabel use of these antibiotics in food-producing animals presents a risk to the public health because ...
... Federal law prohibits the extralabel use of fluoroquinolones in food-producing animals (21 CFR 530.41). The prohibition is based on a finding by the Food and Drug Administration (FDA) that the extralabel use of these antibiotics in food-producing animals presents a risk to the public health because ...
Prescribing Information Only Fluticasone Propionate Nasal Spray
... for prolonged periods with systemic corticosteroids and transferred to topical corticosteroids should be carefully monitored for acute adrenal insufficiency in response to stress. In those patients who have asthma or other clinical conditions requiring long-term systemic corticosteroid treatment, t ...
... for prolonged periods with systemic corticosteroids and transferred to topical corticosteroids should be carefully monitored for acute adrenal insufficiency in response to stress. In those patients who have asthma or other clinical conditions requiring long-term systemic corticosteroid treatment, t ...
Macrolides and ketolides: azithromycin, clarithromycin, telithromycin * Jerry M. Zuckerman, MD
... neutral sugar, cladinose, and an amino sugar, desosamine). In the acidic environment of the stomach, it is rapidly degraded to the 8,9-anhydro-6,9hemiketal and then to the 6,9,9,12-spiroketal form. The hemiketal intermediate may be responsible for the gastrointestinal adverse effects associated with ...
... neutral sugar, cladinose, and an amino sugar, desosamine). In the acidic environment of the stomach, it is rapidly degraded to the 8,9-anhydro-6,9hemiketal and then to the 6,9,9,12-spiroketal form. The hemiketal intermediate may be responsible for the gastrointestinal adverse effects associated with ...
Benzylpenicillin inhibits the renal excretion of acyclovir by OAT1 and
... infections. Approximately 83% of acyclovir is excreted by kidney in its unchanged forms [13]. Renal excretion of acyclovir is reduced by probenecid, a typical inhibitor of OAT [13]. Although neither possesses a typical anionic moiety, the results suggest that the OAT system is responsible for the tu ...
... infections. Approximately 83% of acyclovir is excreted by kidney in its unchanged forms [13]. Renal excretion of acyclovir is reduced by probenecid, a typical inhibitor of OAT [13]. Although neither possesses a typical anionic moiety, the results suggest that the OAT system is responsible for the tu ...
Antifungal curcumin induces reactive oxygen species and triggers
... INTRODUCTION The dimorphic opportunistic pathogen Candida albicans is normally a commensal organism in humans, but when the host is unable to mount an adequate immune response, such as in AIDS, organ transplantation, diabetes, burn or cancer patients, it results in mucosal, cutaneous or invasive myc ...
... INTRODUCTION The dimorphic opportunistic pathogen Candida albicans is normally a commensal organism in humans, but when the host is unable to mount an adequate immune response, such as in AIDS, organ transplantation, diabetes, burn or cancer patients, it results in mucosal, cutaneous or invasive myc ...
Poonam et al - Galaxy of Pharmaceutical Innovations
... Taste masking by bitterness inhibitors The development of a specific universal inhibitor for bitter taste has been widely required in the fields of taste physiology and pharmaceutical sciences, but no such inhibitors has been available.One difficulty in discovering of universal inhibitor for bitter ...
... Taste masking by bitterness inhibitors The development of a specific universal inhibitor for bitter taste has been widely required in the fields of taste physiology and pharmaceutical sciences, but no such inhibitors has been available.One difficulty in discovering of universal inhibitor for bitter ...
(500 mg metronidazole and 100,000 IU nystatin) Vaginal Ovules Vaginal Cream
... should not be used during treatment because they may promote fungal replication. It is possible that adverse effects normally associated with oral administration of metronidazole or nystatin may occur following the vaginal administration of FLAGYSTATIN. Patients should be warned against consuming al ...
... should not be used during treatment because they may promote fungal replication. It is possible that adverse effects normally associated with oral administration of metronidazole or nystatin may occur following the vaginal administration of FLAGYSTATIN. Patients should be warned against consuming al ...
Pharmacogenetic studies of paclitaxel in ovarian cancer pharmacodynamics and
... specific targets such as the Bcr-Abl tyrosine kinase in chronic myeloid leukemia and the development of specific inhibitors like imatinib have been shown to be successful (Druker 2002). However, at the same time as new chemotherapeutic agents are developed today, it is equally important that scienti ...
... specific targets such as the Bcr-Abl tyrosine kinase in chronic myeloid leukemia and the development of specific inhibitors like imatinib have been shown to be successful (Druker 2002). However, at the same time as new chemotherapeutic agents are developed today, it is equally important that scienti ...
INVESTIGATOR’S BROCHURE BUTHIONINE SULFOXIMINE NSC 326231
... intracellular reactive oxygen species and the latter promote the toxic effects of radiation and some antineoplastic drugs or, 5) GSH may interfere with delivery or uptake of antineoplastic agents through its role in amino acid transport. ...
... intracellular reactive oxygen species and the latter promote the toxic effects of radiation and some antineoplastic drugs or, 5) GSH may interfere with delivery or uptake of antineoplastic agents through its role in amino acid transport. ...
FULL PRESCRIBING INFORMATION
... with ADHD should be treated with dexmethylphenidate hydrochloride extended-release capsules. It is generally agreed, however, that pharmacological treatment of ADHD may be needed for extended periods. Nevertheless, the physician who elects to use dexmethylphenidate hydrochloride extended-release cap ...
... with ADHD should be treated with dexmethylphenidate hydrochloride extended-release capsules. It is generally agreed, however, that pharmacological treatment of ADHD may be needed for extended periods. Nevertheless, the physician who elects to use dexmethylphenidate hydrochloride extended-release cap ...
(PSD) July 2016 PBAC Meeting - (Word 86KB)
... endpoint of progression of disability. Daclizumab presents more risk of serious adverse effects than IFN β-1a. Given these factors it is not clear whether use of this product should be permitted at all or whether restricting its use to patients who have failed initial treatment would be appropriate. ...
... endpoint of progression of disability. Daclizumab presents more risk of serious adverse effects than IFN β-1a. Given these factors it is not clear whether use of this product should be permitted at all or whether restricting its use to patients who have failed initial treatment would be appropriate. ...
Cobicistat / Tenofovir disoproxil fumarate / Emtricitabine / Elvitegravir
... with medicines or medical devices. TGA investigates reports received by it to determine any necessary regulatory action. ...
... with medicines or medical devices. TGA investigates reports received by it to determine any necessary regulatory action. ...
Intravenous Anesthesia 1991
... pharmacokinetic sense to titrate the propofol while maintaining a Figure 3: Curves showing time required for 50% decrease in propofol, alfentanil, and sufentanil concentration following constant opioid concentration. Thus, if a drug overdose occurs, it discontinuation of a continuous infusion. will ...
... pharmacokinetic sense to titrate the propofol while maintaining a Figure 3: Curves showing time required for 50% decrease in propofol, alfentanil, and sufentanil concentration following constant opioid concentration. Thus, if a drug overdose occurs, it discontinuation of a continuous infusion. will ...
Hydrochlorothiazide / Olmesartan medoxomil / Amlodipine
... effect is already observed after 2 weeks of treatment. The effect of olmesartan on mortality and morbidity is not yet known. Amlodipine Experimental data suggests that amlodipine binds to both dihydropyridine and nonhydropyridine binding sites. The contractile processes of cardiac muscle and vascula ...
... effect is already observed after 2 weeks of treatment. The effect of olmesartan on mortality and morbidity is not yet known. Amlodipine Experimental data suggests that amlodipine binds to both dihydropyridine and nonhydropyridine binding sites. The contractile processes of cardiac muscle and vascula ...
Radius Health, Inc. - Nasdaq`s INTEL Solutions
... “blue sky” laws, then the holder of Restricted Stock shall thereupon be entitled to effect such Transfer in accordance with the terms of the notice delivered by it to the Corporation. Each certificate or other instrument evidencing the securities issued upon such Transfer (and each certificate or ot ...
... “blue sky” laws, then the holder of Restricted Stock shall thereupon be entitled to effect such Transfer in accordance with the terms of the notice delivered by it to the Corporation. Each certificate or other instrument evidencing the securities issued upon such Transfer (and each certificate or ot ...
Prescribing Information - PI
... serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal of PRILOSEC. (5.11, 7). ----------------------------------------- ADVERSE REACTIONS ----------------------------------------Adults: Mo ...
... serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal of PRILOSEC. (5.11, 7). ----------------------------------------- ADVERSE REACTIONS ----------------------------------------Adults: Mo ...
IN THE NAME OF GOD FAKHRADDIN FAIZI
... Do not exceed recommended dose; do not take for longer than 10 days. Take the drug only for complaints indicated; it is not an anti-inflammatory agent. Avoid the use of other over-the-counter preparations. They may contain acetaminophen, and serious overdosage can occur. If you need an over-thecount ...
... Do not exceed recommended dose; do not take for longer than 10 days. Take the drug only for complaints indicated; it is not an anti-inflammatory agent. Avoid the use of other over-the-counter preparations. They may contain acetaminophen, and serious overdosage can occur. If you need an over-thecount ...
PRODUCT MONOGRAPH PREVACID PREVACID FasTab
... Safety concerns of long-term treatment relate to hypergastrinemia, possible enterochromaffinlike (ECL) effect and carcinoid formation. ECL cell hyperplasia and gastric carcinoid tumours were observed in four animal studies. In two 24-month carcinogenicity studies, Sprague-Dawley rats were treated or ...
... Safety concerns of long-term treatment relate to hypergastrinemia, possible enterochromaffinlike (ECL) effect and carcinoid formation. ECL cell hyperplasia and gastric carcinoid tumours were observed in four animal studies. In two 24-month carcinogenicity studies, Sprague-Dawley rats were treated or ...
EVALUATION OF THE ANTIINFLAMMATORY AND ANALGESIC EFFECTS OF PIROXICAM LOADED MICROEMULSION IN TOPICAL FORMULATIONS
... Piroxicam is a nonsteroidal anti‐inflammatory drug. It has anti‐inflammatory, analgesic and antipyretic activity through inhibition of prostaglandin synthetase, via inhibition of cyclooxygenase enzymes. This study was designed to compare the anti‐inflammatory and analgesic effects of piroxicam in ...
... Piroxicam is a nonsteroidal anti‐inflammatory drug. It has anti‐inflammatory, analgesic and antipyretic activity through inhibition of prostaglandin synthetase, via inhibition of cyclooxygenase enzymes. This study was designed to compare the anti‐inflammatory and analgesic effects of piroxicam in ...
RM-Ii3201 B DIS SPECIFICATION
... Jodhtm. It is also not known whether heparin sodium can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Heparin sodium should be given to a pregnant woman only if clearly needed. Nonteratogenic Effecfx Heparin does not cross the placental barrier. Nurrlng ...
... Jodhtm. It is also not known whether heparin sodium can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Heparin sodium should be given to a pregnant woman only if clearly needed. Nonteratogenic Effecfx Heparin does not cross the placental barrier. Nurrlng ...
product monograph
... be discontinued if markedly elevated CPK levels are measured and/or if the patient develops signs and symptoms indicative of rhabdomyolysis. Although the decision to discontinue ARICEPT should be made based on the clinical judgement of the treating physician, in most post-marketing cases, therapy wa ...
... be discontinued if markedly elevated CPK levels are measured and/or if the patient develops signs and symptoms indicative of rhabdomyolysis. Although the decision to discontinue ARICEPT should be made based on the clinical judgement of the treating physician, in most post-marketing cases, therapy wa ...
1 g powder for injection
... were comparable to those of the controls by weaning. No evidence of teratogenicity or effects on reproduction were noted at this dosage. When administered during late gestation and lactation periods, this dosage of 700 mg/kg/day (approximately 9 times the maximum human dose) did not result in any ad ...
... were comparable to those of the controls by weaning. No evidence of teratogenicity or effects on reproduction were noted at this dosage. When administered during late gestation and lactation periods, this dosage of 700 mg/kg/day (approximately 9 times the maximum human dose) did not result in any ad ...
Azithromycin - Rebound Health
... Fewer than 1% of patients stop taking the drug due to side effects. Nervousness, dermatologic reactions and anaphylaxis have been reported. As with all antimicrobial agents, pseudomembranous colitis can occur during and up to several weeks after azithromycin therapy. This drug may interfere with the ...
... Fewer than 1% of patients stop taking the drug due to side effects. Nervousness, dermatologic reactions and anaphylaxis have been reported. As with all antimicrobial agents, pseudomembranous colitis can occur during and up to several weeks after azithromycin therapy. This drug may interfere with the ...