Product Information
... Not applicable. If mothers are drinking caffeine containing fluids, this should be taken into consideration when determining the dose for the neonate. Genotoxicity Assays for bacterial and mammalian mutagenicity in vitro, and for clastogenicity in vitro and in vivo generally show negative results fo ...
... Not applicable. If mothers are drinking caffeine containing fluids, this should be taken into consideration when determining the dose for the neonate. Genotoxicity Assays for bacterial and mammalian mutagenicity in vitro, and for clastogenicity in vitro and in vivo generally show negative results fo ...
ABC Clinical Guide 2003 - American Botanical Council
... amounts of saw palmetto berries may cause diarrhea while ingesting saw palmetto on an empty stomach may cause nausea. High blood pressure occurred in only 3% of patients who took saw palmetto extract in a large clinical trial of 951 men although this effect is not normally associated with the use of ...
... amounts of saw palmetto berries may cause diarrhea while ingesting saw palmetto on an empty stomach may cause nausea. High blood pressure occurred in only 3% of patients who took saw palmetto extract in a large clinical trial of 951 men although this effect is not normally associated with the use of ...
Berberine Monograph - Alternative Medicine Review
... Diarrhea caused by Vibrio cholera and Escherichia coli has been the focus of numerous berberine studies, and results indicate several mechanisms which may explain its ability to inhibit bacterial diarrhea. An animal study found berberine reduced the intestinal secretion of water and electrolytes ind ...
... Diarrhea caused by Vibrio cholera and Escherichia coli has been the focus of numerous berberine studies, and results indicate several mechanisms which may explain its ability to inhibit bacterial diarrhea. An animal study found berberine reduced the intestinal secretion of water and electrolytes ind ...
Martindale: The Complete Drug Reference
... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...
... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...
Effects of a Novel Cholecystokinin (CCK)
... collimator, interfaced to an ADAC 3350 computer (Analytical Development Corp., San Jose, CA) was used for imaging. 99mTc and "'In were surveyed through 140- and 247-keV windows, respectively. Images were obtained for 60 s for 99mTc and 120 s for "'In. Subjects remained seated between counts but stoo ...
... collimator, interfaced to an ADAC 3350 computer (Analytical Development Corp., San Jose, CA) was used for imaging. 99mTc and "'In were surveyed through 140- and 247-keV windows, respectively. Images were obtained for 60 s for 99mTc and 120 s for "'In. Subjects remained seated between counts but stoo ...
Opioid Substitution Therapy Under National AIDS Control
... female sex workers has also been reduced. This has been possible due to massive efforts from all the stakeholders concerned, including the civil society, affected communities, technical experts, as well as the various divisions working within the Department of AIDS Control (DAC). While there is much ...
... female sex workers has also been reduced. This has been possible due to massive efforts from all the stakeholders concerned, including the civil society, affected communities, technical experts, as well as the various divisions working within the Department of AIDS Control (DAC). While there is much ...
Dabigatran etexilate for the prevention of stroke in patients with
... because many patients are only identified with long-term monitoring [2] or after presenting with complications [3] . AF is associated with significant morbidity, the most serious being systemic embolization and stroke, which, depending on patient risk factors, can be as high as 10% per year [1] . Pa ...
... because many patients are only identified with long-term monitoring [2] or after presenting with complications [3] . AF is associated with significant morbidity, the most serious being systemic embolization and stroke, which, depending on patient risk factors, can be as high as 10% per year [1] . Pa ...
... equipotent to salmeterol 50 µg Diskhaler® was estimated by fitting a straight line to the adjusted 12 h average FEV1 for the three doses of formoterol. The 95% confidence interval (CI) for the equipotent dose was calculated by using Fieller's method. Onset of action was evaluated using Wilcoxon's si ...
N N S H N CH3 N CH3
... The efficacy of intramuscular olanzapine for injection for the treatment of agitation was established in 3 short-term (24 hours of IM treatment) placebo-controlled trials in agitated inpatients from two diagnostic groups: schizophrenia and Bipolar I Disorder (manic or mixed episodes). Each of the tr ...
... The efficacy of intramuscular olanzapine for injection for the treatment of agitation was established in 3 short-term (24 hours of IM treatment) placebo-controlled trials in agitated inpatients from two diagnostic groups: schizophrenia and Bipolar I Disorder (manic or mixed episodes). Each of the tr ...
PRESCRIBING INFORMATION CODEINE 15
... CYP2D6*2x2 genotype. These individuals convert codeine into its active metabolite, morphine, more rapidly and completely than other people. This rapid conversion results in higher than expected serum morphine levels. Even at labeled dosage regimens, individuals who are ultra-rapid metabolizers may e ...
... CYP2D6*2x2 genotype. These individuals convert codeine into its active metabolite, morphine, more rapidly and completely than other people. This rapid conversion results in higher than expected serum morphine levels. Even at labeled dosage regimens, individuals who are ultra-rapid metabolizers may e ...
Original salbutamol versus similar salbutamol in
... It meets the same quality criteria as those of the original medicine and its safety and efficacy data are based on the active ingredient background material, but does not have its own research or development. In Argentina, based on the health risk classification adopted by the ANMAT, salbutamol is i ...
... It meets the same quality criteria as those of the original medicine and its safety and efficacy data are based on the active ingredient background material, but does not have its own research or development. In Argentina, based on the health risk classification adopted by the ANMAT, salbutamol is i ...
i Preface
... Directorate of Health Centres Directorate of Health Centres College of Health Science Directorate of Material Management ...
... Directorate of Health Centres Directorate of Health Centres College of Health Science Directorate of Material Management ...
Paediatric Formulary - King`s College Hospital NHS Foundation Trust
... Due to every child requiring a different dose, the fact that most medicines are produced in quantities and strengths suitable for adults, and therefore that most doses are very small and require decimal points in terms of volume; it is easy to see why there is a lot of potential for error when presc ...
... Due to every child requiring a different dose, the fact that most medicines are produced in quantities and strengths suitable for adults, and therefore that most doses are very small and require decimal points in terms of volume; it is easy to see why there is a lot of potential for error when presc ...
MasterThesis_Ulvestad
... Pharmacokinetics refers to the processes of drug absorption, distribution, metabolism and elimination, while pharmacodynamic processes involve the mechanisms of drug action. Drug efficacy reflects the interplay of pharmacokinetics and pharmacodynamics (Buxton, 2006). In drug development, it is of im ...
... Pharmacokinetics refers to the processes of drug absorption, distribution, metabolism and elimination, while pharmacodynamic processes involve the mechanisms of drug action. Drug efficacy reflects the interplay of pharmacokinetics and pharmacodynamics (Buxton, 2006). In drug development, it is of im ...
medicine - Deutsches Ärzteblatt
... In patients with severely impaired renal function with a creatinine clearance <30 mL/min, a reduction in subsequent doses is recommended, since accumulation of amoxicillin is to be expected. Patients with a creatinine clearance of 20–30 mL/min should receive two thirds of the normal dose, and those ...
... In patients with severely impaired renal function with a creatinine clearance <30 mL/min, a reduction in subsequent doses is recommended, since accumulation of amoxicillin is to be expected. Patients with a creatinine clearance of 20–30 mL/min should receive two thirds of the normal dose, and those ...
Bupropion Orion modified release tablet ENG SmPC
... The recommended starting dose is 150 mg, given once daily. An optimal dose was not established in clinical studies. If no improvement is seen after 4 weeks treatment at 150 mg, the dose may be increased to 300 mg, given once daily. There should be an interval of at least 24 hours between successive ...
... The recommended starting dose is 150 mg, given once daily. An optimal dose was not established in clinical studies. If no improvement is seen after 4 weeks treatment at 150 mg, the dose may be increased to 300 mg, given once daily. There should be an interval of at least 24 hours between successive ...
Prednisolone and hiccups Introduction
... presents five patients who developed hiccups after receiving dexamethasone for chemotherapy-induced nausea and vomiting. However, switching dexamethasone to an equipotent dosage of either methylprednisolone or prednisolone resolved the hiccups [11]. This was also seen in a study of 40 cancer patient ...
... presents five patients who developed hiccups after receiving dexamethasone for chemotherapy-induced nausea and vomiting. However, switching dexamethasone to an equipotent dosage of either methylprednisolone or prednisolone resolved the hiccups [11]. This was also seen in a study of 40 cancer patient ...
MORPHINE Juno
... Adults: The usual adult dose by intramuscular or subcutaneous injection is 5 to 20 milligrams. Doses may be repeated every 4 to 6 hours. Morphine may be administered intravenously when a rapid onset of action is desired. The usual adult dose is 2.5 to 15 milligrams diluted in 4 to 5 mL of water for ...
... Adults: The usual adult dose by intramuscular or subcutaneous injection is 5 to 20 milligrams. Doses may be repeated every 4 to 6 hours. Morphine may be administered intravenously when a rapid onset of action is desired. The usual adult dose is 2.5 to 15 milligrams diluted in 4 to 5 mL of water for ...
Regulatory requirements for the development of medicinal products
... [2] Substantial: i.e. in general 50,000 patients, but nature and severity of the condition should be taken into account (5). ...
... [2] Substantial: i.e. in general 50,000 patients, but nature and severity of the condition should be taken into account (5). ...
HIGHLIGHTS OF PRESCRIBING INFORMATION
... than 5 years of age have not been established. The dosage of RISPERDAL® should be individualized according to the response and tolerability of the patient. The total daily dose of RISPERDAL® can be administered once daily, or half the total daily dose can be administered twice daily. Dosing should b ...
... than 5 years of age have not been established. The dosage of RISPERDAL® should be individualized according to the response and tolerability of the patient. The total daily dose of RISPERDAL® can be administered once daily, or half the total daily dose can be administered twice daily. Dosing should b ...
Enhanced Therapeutic Benefit of Quercetin–Phospholipid Complex
... activity in vivo. A severe limitation exists and is imputable to very poor absorption of quercetin when administered orally. To overcome this limitation, development of a value added herbal formulation in combination with phospholipids has been made which has better absorption and utilization profil ...
... activity in vivo. A severe limitation exists and is imputable to very poor absorption of quercetin when administered orally. To overcome this limitation, development of a value added herbal formulation in combination with phospholipids has been made which has better absorption and utilization profil ...
Breo Ellipta
... treatments for management of asthma or COPD symptoms should be considered. Systemic Steroid Replacement by Inhaled Steroid Particular care is needed for patients who have been transferred from systemically active corticosteroids to inhaled corticosteroids because deaths due to adrenal insufficiency ...
... treatments for management of asthma or COPD symptoms should be considered. Systemic Steroid Replacement by Inhaled Steroid Particular care is needed for patients who have been transferred from systemically active corticosteroids to inhaled corticosteroids because deaths due to adrenal insufficiency ...
Prepared for NCI by Technical Resources International, Inc I.
... dose level, mutagenicity decreased to approximately 20% of what was observed without HMF present. The authors noted that HMF, like other furan compounds tested, appeared to show a bifunctionality by exhibiting a weak mutagenic effect (doses on the order of 1 or more mg/plate) and a desmutagenic effe ...
... dose level, mutagenicity decreased to approximately 20% of what was observed without HMF present. The authors noted that HMF, like other furan compounds tested, appeared to show a bifunctionality by exhibiting a weak mutagenic effect (doses on the order of 1 or more mg/plate) and a desmutagenic effe ...
guideline for the management of tricyclic antidepressant overdose
... significant weaknesses, a strong correlation has consistently been shown between level of consciousness and the development of serious complications including death, hypoventilation and aspiration pneumonia following drug overdose. Of interest, both Hulten et al28 and Emerman et al29 showed that TCA ...
... significant weaknesses, a strong correlation has consistently been shown between level of consciousness and the development of serious complications including death, hypoventilation and aspiration pneumonia following drug overdose. Of interest, both Hulten et al28 and Emerman et al29 showed that TCA ...
An Evidence-Based Systematic Review of Goji
... Statistically significant evidence of benefit from >2 properly randomized trials (RCTs), OR evidence from one properly conducted RCT AND one properly conducted meta-analysis, OR evidence from multiple RCTs with a clear majority of the properly conducted trials showing statistically significant evide ...
... Statistically significant evidence of benefit from >2 properly randomized trials (RCTs), OR evidence from one properly conducted RCT AND one properly conducted meta-analysis, OR evidence from multiple RCTs with a clear majority of the properly conducted trials showing statistically significant evide ...