Fructose, Glucocorticoids and Adipose Tissue: Implications for the
... to anaerobic glycolysis and increases the secretion of a number of inflammation-related adipokines accompanied with cell damage [9]. On the other hand, this inflammatory response is also a key factor for modulating insulin sensitivity in adipose tissue and the development of obesity-associated disea ...
... to anaerobic glycolysis and increases the secretion of a number of inflammation-related adipokines accompanied with cell damage [9]. On the other hand, this inflammatory response is also a key factor for modulating insulin sensitivity in adipose tissue and the development of obesity-associated disea ...
UNIT I The cell and general physiology
... “activated” RNA molecules to the growing RNA molecule until the polymerase reaches the chainterminating sequence on the template DNA molecule. TMP12 30–31 14.A) An oncogene is a gene that is either abnormally activated or mutated in such a way that its product causes uncontrolled cell growth. A prot ...
... “activated” RNA molecules to the growing RNA molecule until the polymerase reaches the chainterminating sequence on the template DNA molecule. TMP12 30–31 14.A) An oncogene is a gene that is either abnormally activated or mutated in such a way that its product causes uncontrolled cell growth. A prot ...
catalogue 2012 - olimp
... Over 20 years of experience in the production of nutrients, the top specialists working at our company and the leading world experts in the area of sport nutrition with whom we cooperate on a regular basis and the products themselves, put us at the top of the most innovative companies implementing ...
... Over 20 years of experience in the production of nutrients, the top specialists working at our company and the leading world experts in the area of sport nutrition with whom we cooperate on a regular basis and the products themselves, put us at the top of the most innovative companies implementing ...
The effect of short chain fatty acids on glucose homeostasis
... chain fatty acid (SCFA) production from roughages by rumen microbes (Flatt et al., 1958). The physical structure of roughages stimulates rumen motility (McDonald et al., 2002). Besides these positive effects of roughages on health and welfare, it is uncertain how roughages influence glucose homeosta ...
... chain fatty acid (SCFA) production from roughages by rumen microbes (Flatt et al., 1958). The physical structure of roughages stimulates rumen motility (McDonald et al., 2002). Besides these positive effects of roughages on health and welfare, it is uncertain how roughages influence glucose homeosta ...
International Journal of Research and Reviews in Pharmacy
... described as its ‘fifth tendon’. The muscle fibres arise from the lower part of the medial surface of the shaft of the fibula, the adjoining anterior surface of the interosseous membrane, and the anterior crural intermuscular septum. The tendon passes behind the superior extensor retinaculum and wit ...
... described as its ‘fifth tendon’. The muscle fibres arise from the lower part of the medial surface of the shaft of the fibula, the adjoining anterior surface of the interosseous membrane, and the anterior crural intermuscular septum. The tendon passes behind the superior extensor retinaculum and wit ...
Bioinformatics analysis of FRG1
... dystrophy (FSHD). Since its discovery in 1996, through many experimental evidences, it has been associated primarily with myogenesis in FSHD patients as well as in normal individuals. Moreover, studies have reported additional functions. Till date the unequivocal molecular mechanism remains unclear. ...
... dystrophy (FSHD). Since its discovery in 1996, through many experimental evidences, it has been associated primarily with myogenesis in FSHD patients as well as in normal individuals. Moreover, studies have reported additional functions. Till date the unequivocal molecular mechanism remains unclear. ...
fiber types in mammalian skeletal muscles
... their contractile properties as fast and slow since the first half of the 19th century. However, it is during the last 40 years that the notion of muscle fiber type diversity has rapidly progressed leading to the identification of four major fiber types in adult mammalian skeletal muscles. Until aro ...
... their contractile properties as fast and slow since the first half of the 19th century. However, it is during the last 40 years that the notion of muscle fiber type diversity has rapidly progressed leading to the identification of four major fiber types in adult mammalian skeletal muscles. Until aro ...
fiber types in mammalian skeletal muscles
... Scientists have been aware that skeletal muscles can be distinguished on the basis of their color as red or white and their contractile properties as fast and slow since the first half of the 19th century. However, it is during the last 40 years that the notion of muscle fiber type diversity has rap ...
... Scientists have been aware that skeletal muscles can be distinguished on the basis of their color as red or white and their contractile properties as fast and slow since the first half of the 19th century. However, it is during the last 40 years that the notion of muscle fiber type diversity has rap ...
Unravelling Insulin Resistance
... Persaud, SJ. et al. Gymnema sylvestra stimulates insulin release in vitro by increased membrane permeability. J Endocrinol, 1999, Vol. 163, pp. 207-212. Eagle Pharmaceuticals – 2006 © ...
... Persaud, SJ. et al. Gymnema sylvestra stimulates insulin release in vitro by increased membrane permeability. J Endocrinol, 1999, Vol. 163, pp. 207-212. Eagle Pharmaceuticals – 2006 © ...
PDQ Physiology
... from nuclear DNA by mRNA (Figure 1–2). Ribosomes can be attached to the cytosolic side of the rough endoplasmic reticulum, or they can be free in the cytosol. Attached ribosomes synthesize proteins that are eventually secreted from the cell, lysosomal proteins, and cell membrane proteins. Free ribos ...
... from nuclear DNA by mRNA (Figure 1–2). Ribosomes can be attached to the cytosolic side of the rough endoplasmic reticulum, or they can be free in the cytosol. Attached ribosomes synthesize proteins that are eventually secreted from the cell, lysosomal proteins, and cell membrane proteins. Free ribos ...
Isoenzymes in Clinical Diagnosis
... many diseases. They are protein catalysts, some of which enter the serum from damaged tissues. Because they are catalysts, they are more easily detected than many other substances. Amylase released from the diseased pancreas,1 and phosphatase released from several tissues2 have been studied for many ...
... many diseases. They are protein catalysts, some of which enter the serum from damaged tissues. Because they are catalysts, they are more easily detected than many other substances. Amylase released from the diseased pancreas,1 and phosphatase released from several tissues2 have been studied for many ...
Glucose Regulation by Dr Sarma
... Glucose Receptors, GLUT 1-14 Controlling Hormones, Insulin, Glucagon, Cortisol, Epinephrine etc., Insulin Signaling sequences, Glucagon signaling Effector Cells – Muscles, Liver, Brain, Heart and Adipose tissue ...
... Glucose Receptors, GLUT 1-14 Controlling Hormones, Insulin, Glucagon, Cortisol, Epinephrine etc., Insulin Signaling sequences, Glucagon signaling Effector Cells – Muscles, Liver, Brain, Heart and Adipose tissue ...
Full-Text PDF
... 1-mediated apoptosis leading to increased cell survival. Pulmonary artery endothelial cells isolated from idiopathic PAH patient lungs had decreased levels of TopBP1 mRNA and protein compared to controls. Decreased expression of TopBP1 was associated with increased susceptibility to hydroxyurea indu ...
... 1-mediated apoptosis leading to increased cell survival. Pulmonary artery endothelial cells isolated from idiopathic PAH patient lungs had decreased levels of TopBP1 mRNA and protein compared to controls. Decreased expression of TopBP1 was associated with increased susceptibility to hydroxyurea indu ...
Bile-Acid Sequestrants: Glucose-Lowering Mechanisms - HAL
... Even though no difference was found in the size of the total bile acid pool, the contribution of specific bile acid species to the pool was altered in T2D. Thus, the pool of the secondary bile acid DCA was elevated as was the DCA input rate, whereas the CDCA pool decreased [8]. The CA pool was unch ...
... Even though no difference was found in the size of the total bile acid pool, the contribution of specific bile acid species to the pool was altered in T2D. Thus, the pool of the secondary bile acid DCA was elevated as was the DCA input rate, whereas the CDCA pool decreased [8]. The CA pool was unch ...
Regulation of Translation by Essential Amino Acids and Glucose in
... Table 1. Ingredient and chemical composition of total mixed ration........................................... 29 Table 2. Antibodies used for primary incubation of bovine mammary and muscle proteins....... 34 Table 3. Primer sequences for qPCR in bovine mammary and muscle tissue..................... ...
... Table 1. Ingredient and chemical composition of total mixed ration........................................... 29 Table 2. Antibodies used for primary incubation of bovine mammary and muscle proteins....... 34 Table 3. Primer sequences for qPCR in bovine mammary and muscle tissue..................... ...
REVIEWS - Unisciel
... filaments from adjacent sarcomeres28,29. The two Ig domains that are carboxy-terminal to this unique sequence contain a binding site for obscurin, a giant multimodular protein that probably has signalling functions31. The relationship between titin and actin within the Z-line region is not yet clear ...
... filaments from adjacent sarcomeres28,29. The two Ig domains that are carboxy-terminal to this unique sequence contain a binding site for obscurin, a giant multimodular protein that probably has signalling functions31. The relationship between titin and actin within the Z-line region is not yet clear ...
Print - Circulation Research
... activate Akt/PKB and GSK-3 activity in both cardiomyocytes and Langendorff-perfused hearts.8 In cardiac muscle, cell adhesion and the cardiomyocyte stretch sensor machinery play key roles in the complex mechanism leading to human DCM and associated heart failures.9 Indeed, dilated cardio- ...
... activate Akt/PKB and GSK-3 activity in both cardiomyocytes and Langendorff-perfused hearts.8 In cardiac muscle, cell adhesion and the cardiomyocyte stretch sensor machinery play key roles in the complex mechanism leading to human DCM and associated heart failures.9 Indeed, dilated cardio- ...
INTERORGAN AMMONIA TRAFFICKING
... • Normally ammonia is present at nontoxic level • Hyperammonia in chronic liver disease is adapted increased uptake in muscle but this adaptive mechanism fells in ALF due to massive rapid hepatocyte damage leading to sudden increase in ammonia,thus cerebral edema. • Ammonia lowering therapy help in ...
... • Normally ammonia is present at nontoxic level • Hyperammonia in chronic liver disease is adapted increased uptake in muscle but this adaptive mechanism fells in ALF due to massive rapid hepatocyte damage leading to sudden increase in ammonia,thus cerebral edema. • Ammonia lowering therapy help in ...
The malonyl CoA axis as a potential target for treating ischaemic
... AMPK has become a protein, with wide interest among many investigators, due to its ability to increase energy metabolism in times of stress. In regard to the stress of ischaemia/reperfusion injury, many groups have postulated that AMPK activation would be beneficial in this scenario via increasing gl ...
... AMPK has become a protein, with wide interest among many investigators, due to its ability to increase energy metabolism in times of stress. In regard to the stress of ischaemia/reperfusion injury, many groups have postulated that AMPK activation would be beneficial in this scenario via increasing gl ...
Open the publication - UEF Electronic Publications
... transformation is Pgc-1α. Exercise training induces the upregulation of muscle Pgc-1α levels which improves not only muscle fibre-type switching (from high speed glycolytic towards high endurance oxidative fibres) through calcium cascade but also mitochondrial biogenesis, fatty acid oxidation and va ...
... transformation is Pgc-1α. Exercise training induces the upregulation of muscle Pgc-1α levels which improves not only muscle fibre-type switching (from high speed glycolytic towards high endurance oxidative fibres) through calcium cascade but also mitochondrial biogenesis, fatty acid oxidation and va ...
Human Cardiac Troponin Complex. Structure and Functions
... data of Lindhout and Sykes [73] indicate that in the presence of Ca2+, residues 132-135 of hcTnI interact with a hydrophobic region on the surface of the C-terminal domain of TnC, the following residues 135-140 form an α-helix that interacts with E- and H-helices of TnC, while residues 141-148 do no ...
... data of Lindhout and Sykes [73] indicate that in the presence of Ca2+, residues 132-135 of hcTnI interact with a hydrophobic region on the surface of the C-terminal domain of TnC, the following residues 135-140 form an α-helix that interacts with E- and H-helices of TnC, while residues 141-148 do no ...
Development, validation and biological application of
... discussing science. I still do not understand why, being such an intelligent person, he still supports the Oklahoma Sooners, but to each his own I suppose. I don’t think I have ever met anyone as enthusiastic as Dr. John Jones when it comes to tackling down novel methods and ideas. He is always read ...
... discussing science. I still do not understand why, being such an intelligent person, he still supports the Oklahoma Sooners, but to each his own I suppose. I don’t think I have ever met anyone as enthusiastic as Dr. John Jones when it comes to tackling down novel methods and ideas. He is always read ...
Glycogen branches out: new perspectives on the role of glycogen
... a recently described transgenic mouse model that lacks the muscle isoform of glycogen synthase and thus muscle glycogen stores (44). The authors observed no change in exercise capacity compared with wild-type animals (46), but there was an increase in type I fiber content in the gastrocnemius muscle ...
... a recently described transgenic mouse model that lacks the muscle isoform of glycogen synthase and thus muscle glycogen stores (44). The authors observed no change in exercise capacity compared with wild-type animals (46), but there was an increase in type I fiber content in the gastrocnemius muscle ...
attached paper highlights
... demand such as cold, exercise, and fasting. Data are accumulating which show PGC-1a to be a master regulator of mitochondrial biogenesis in mammals. Ectopic expression of PGC-1a in myotubes strongly induces the expression of downstream transcription factors such as NRFs and Tfam.17 Unlike NRFs or Tf ...
... demand such as cold, exercise, and fasting. Data are accumulating which show PGC-1a to be a master regulator of mitochondrial biogenesis in mammals. Ectopic expression of PGC-1a in myotubes strongly induces the expression of downstream transcription factors such as NRFs and Tfam.17 Unlike NRFs or Tf ...