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Biology Final Exam Vocabulary Review
Biology Final Exam Vocabulary Review

... new traits. 2. __________________ is the process of making a genetically identical copy of a gene or organism. 3. __________________ contains a combination of genes from more than one organism. 4. A __________________ organism has one or more genes from another organism inserted into its genome. 5. ...
268 Skin cancer
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Christine Yiwen Yeh - The Second Draft: The Human Epigenome for novel Diagnoses and Therapies
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... 9. Circle the letter of the first step in protein synthesis. a. Transfer RNA carries amino acids to the ribosome. b. The ribosome releases the completed protein chain. c. Messenger RNA enters the cytoplasm and attaches to a ribosome. d. DNA “unzips” to direct the production of a strand of messenger ...
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Genetic screens, sevenless revisited, pathways and paper techniques
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... parents to offspring •A map of SNPs for flies exists •Mapping the inheritance of a phenotype to the inheritance of SNPs allows the rapid mapping of mutations to regions less than 50kb FOR X-RAY BASED MUTATIONS: •Because these are large scale chromosomal rearrangements or deletions, can often be dete ...
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PowerPoint 演示文稿

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ADVANCES IN COCHLEAR IMPLANTATION

... mutation from each parent in both copies of a particular gene and develops a health condition. If the child inherits only one copy of the gene with the mutation, he/she will be a carrier of the condition but will not develop it. When 2 parents are carriers of the same mutation, their children have a ...
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CHAPTER 9 DNA: The Genetic Material ACROSS

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... 19. As male children get older, some begin to closely resemble their fathers and have no resemblance to their mothers. Which statement best explains this observation? 1) Several sperm fertilized the egg, so the fertilized egg contained more genes from their father. 2) More genes are inherited from t ...
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... suppressor genes. Cancers can be caused by DNA changes that turn on oncogenes or turn off tumor suppressor genes. Some people inherit DNA changes from a parent that increase their risk for certain types of cancer. Researchers are studying families that have many cases of WM to try to find the genes ...
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...  ISH is a type of hybridization in which a DNA “probe” is labeled F with fluorescent molecules so that it can be seen with a microscope. FISH is a urine-based genetic assay for the diagnosis and surveillance of bladder cancer. It provides the most sensitive detection of bladder cancer available tod ...
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... “I’m only 20 years old. How did I get ovarian cancer? Isn’t this a disease of older women? “Typically ovarian cancer does affect older women. However, you may have a genetic predisposition for it. Cancer cells have mutations in specific genes that regulate cell division. When they are mutated, cell ...
Lynch syndrome genetics handout 2012
Lynch syndrome genetics handout 2012

... There are two copies of the MLH1, MSH2/EPCAM, MSH6, and PMS2 genes in each cell of your body.   Recall that one copy is received from your mother and the other copy is received from your father.   During the course of an individual’s lifetime, these genes can acquire alterations and stop functionin ...
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... QUESTION 7. Total of 8 points 1. In some association studies of depression and bipolar disorders, correlations to specific alleles are only obvious when participants are divided into subgroups based on symptoms. What do you think could be the biological basis for this? 4 points Symptoms define subg ...
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Oncogenomics



Oncogenomics is a relatively new sub-field of genomics that applies high throughput technologies to characterize genes associated with cancer. Oncogenomics is synonymous with ""cancer genomics"". Cancer is a genetic disease caused by accumulation of mutations to DNA leading to unrestrained cell proliferation and neoplasm formation. The goal of oncogenomics is to identify new oncogenes or tumor suppressor genes that may provide new insights into cancer diagnosis, predicting clinical outcome of cancers, and new targets for cancer therapies. The success of targeted cancer therapies such as Gleevec, Herceptin, and Avastin raised the hope for oncogenomics to elucidate new targets for cancer treatment.Besides understanding the underlying genetic mechanisms that initiates or drives cancer progression, one of the main goals of oncogenomics is to allow for the development of personalized cancer treatment. Cancer develops due to an accumulation of mutations in DNA. These mutations accumulate randomly, and thus, different DNA mutations and mutation combinations exist between different individuals with the same type of cancer. Thus, identifying and targeting specific mutations which have occurred in an individual patient may lead to increased efficacy of cancer therapy.The completion of the Human Genome Project has greatly facilitated the field of oncogenomics and has increased the abilities of researchers to find cancer causing genes. In addition, the sequencing technologies now available for sequence generation and data analysis have been applied to the study of oncogenomics. With the amount of research conducted on cancer genomes and the accumulation of databases documenting the mutational changes, it has been predicted that the most important cancer-causing mutations, rearrangements, and altered expression levels will be cataloged and well characterized within the next decade.Cancer research may look either on the genomic level at DNA mutations, the epigenetic level at methylation or histone modification changes, the transcription level at altered levels of gene expression, or the protein level at altered levels of protein abundance and function in cancer cells. Oncogenomics focuses on the genomic, epigenomic, and transcript level alterations in cancer.
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