Cross-talk between cell-cycle control and the environment
... The plant cell cycle is also governed by CDKs as that of other eukaryotes. For instance, eight classes of CDKs (CDKA to CDKG, and CDK-like kinases—CKLs) have been identified in Arabidopsis. A-type CDKs are the best-characterized group in plants. Members of this group bear the highest sequence identi ...
... The plant cell cycle is also governed by CDKs as that of other eukaryotes. For instance, eight classes of CDKs (CDKA to CDKG, and CDK-like kinases—CKLs) have been identified in Arabidopsis. A-type CDKs are the best-characterized group in plants. Members of this group bear the highest sequence identi ...
fulltext
... Tardigrades are known for being resistant to extreme conditions, including tolerance to ionising and UV radiation in both the hydrated and the dehydrated state. It is known that these factors may cause damage to DNA. It has recently been shown that single and double DNA strand breaks occur when tard ...
... Tardigrades are known for being resistant to extreme conditions, including tolerance to ionising and UV radiation in both the hydrated and the dehydrated state. It is known that these factors may cause damage to DNA. It has recently been shown that single and double DNA strand breaks occur when tard ...
CHK2 kinase: cancer susceptibility and cancer therapy – two sides
... function, combined with genotoxic agents could have therapeutic value in tumours that already possess other defects in the DNA-damage response, such as p53 deficiency, by preventing cell-cycle arrest and DNA repair and by activating cell death9. So, why would you wish to therapeutically target a kin ...
... function, combined with genotoxic agents could have therapeutic value in tumours that already possess other defects in the DNA-damage response, such as p53 deficiency, by preventing cell-cycle arrest and DNA repair and by activating cell death9. So, why would you wish to therapeutically target a kin ...
Ciz1 cooperates with cyclin-A–CDK2 to activate mammalian DNA
... inactivating CDC6 and then, as its levels rise in late G1, activating the DNA replication machinery. Reversal of the natural order in which nuclei are exposed to cyclins E and A blocks initiation in vitro (Coverley et al., 2002), highlighting the rigid requirement for their sequential activity and t ...
... inactivating CDC6 and then, as its levels rise in late G1, activating the DNA replication machinery. Reversal of the natural order in which nuclei are exposed to cyclins E and A blocks initiation in vitro (Coverley et al., 2002), highlighting the rigid requirement for their sequential activity and t ...
Science Flashcard Printouts.doc
... This German botanist was the first to propose that the cell nucleus plays a part in cellular reproduction. ...
... This German botanist was the first to propose that the cell nucleus plays a part in cellular reproduction. ...
Slide 1
... If these mutagens interact with DNA, they can produce mutations at high rates. Some compounds interfere with base-pairing, increasing the error rate of DNA replication. Others weaken the DNA strand, causing breaks and inversions that produce chromosomal mutations. Cells can sometimes repair the dama ...
... If these mutagens interact with DNA, they can produce mutations at high rates. Some compounds interfere with base-pairing, increasing the error rate of DNA replication. Others weaken the DNA strand, causing breaks and inversions that produce chromosomal mutations. Cells can sometimes repair the dama ...
Translational Repression of C. elegans p53 by GLD
... 2003; Vassilev et al., 2004). Such a therapeutic approach highlights the need to uncover additional pathways and mechanisms that negatively regulate p53 levels or activity. Most studies on p53 signaling have been conducted in cell culture-based systems, and their translation into mouse models is oft ...
... 2003; Vassilev et al., 2004). Such a therapeutic approach highlights the need to uncover additional pathways and mechanisms that negatively regulate p53 levels or activity. Most studies on p53 signaling have been conducted in cell culture-based systems, and their translation into mouse models is oft ...
Plant centromeres: structure and control Eric J Richards and R Kelly
... controlling and/or mediating sister chromatid cohesion in metaphase (of mitosis and meiosis II) [19,20]. A number of highly reiterated repeats that reside in centromere regions in plant species have been described [21–24,25•,26•,27,28] (see Table 1 for a partial list). Because most of these DNA repe ...
... controlling and/or mediating sister chromatid cohesion in metaphase (of mitosis and meiosis II) [19,20]. A number of highly reiterated repeats that reside in centromere regions in plant species have been described [21–24,25•,26•,27,28] (see Table 1 for a partial list). Because most of these DNA repe ...
Document
... Mendel’s Law of Segregation A. Law of Segregation states that a pair of factors (alleles) is segregated, or separated, during the formation of gametes (reproductive cells) (1) When two gametes combine during fertilization, the offspring have two factors controlling a specific trait (Gg) ...
... Mendel’s Law of Segregation A. Law of Segregation states that a pair of factors (alleles) is segregated, or separated, during the formation of gametes (reproductive cells) (1) When two gametes combine during fertilization, the offspring have two factors controlling a specific trait (Gg) ...
Obligate phototrophy in cyanobacteria: more than a lack of sugar
... but could not be maintained. Thus lack of sugar transport could explain cyanobacterial obligate autotrophy. However, at least in Synechococcus PCC7942, acquisition of such a transport capacity created a metabolic disequilibrium barely compatible with survival. z 1998 Federation of European Microbiol ...
... but could not be maintained. Thus lack of sugar transport could explain cyanobacterial obligate autotrophy. However, at least in Synechococcus PCC7942, acquisition of such a transport capacity created a metabolic disequilibrium barely compatible with survival. z 1998 Federation of European Microbiol ...
DNA Evolution 3.1 Troubleshooting and Debugging Guide
... © 2013 StorageDNA, Inc. All rights reserved. The owner or authorized user of a valid copy of DNA Evolution may reproduce this publication for the purpose of learning to use such software. No part of this publication may be reproduced or transmitted for commercial purposes, such as ...
... © 2013 StorageDNA, Inc. All rights reserved. The owner or authorized user of a valid copy of DNA Evolution may reproduce this publication for the purpose of learning to use such software. No part of this publication may be reproduced or transmitted for commercial purposes, such as ...
Trichothiodystrophy: Update on the sulfur
... of the XPD gene. Rarely, mutated XPB gene or an unidentified TTD-A gene may result in TTD. In UVsensitive TTD, the TFIIH transcription factor containing XPB and XPD helicase activities necessary for both transcription initiation and DNA repair is damaged. Beyond deficiency in the NER pathway, it is ...
... of the XPD gene. Rarely, mutated XPB gene or an unidentified TTD-A gene may result in TTD. In UVsensitive TTD, the TFIIH transcription factor containing XPB and XPD helicase activities necessary for both transcription initiation and DNA repair is damaged. Beyond deficiency in the NER pathway, it is ...
Aberrant DNA methylation in cancer: potential clinical
... occurring modification of human DNA (Fig. 1) and results from the activity of a family of DNA methyltransferase (DNMT) enzymes that catalyse the addition of a methyl group to cytosine residues at CpG dinucleotides (Ref. 1). Alterations in DNA methylation are regarded as epigenetic, and not genetic, ...
... occurring modification of human DNA (Fig. 1) and results from the activity of a family of DNA methyltransferase (DNMT) enzymes that catalyse the addition of a methyl group to cytosine residues at CpG dinucleotides (Ref. 1). Alterations in DNA methylation are regarded as epigenetic, and not genetic, ...
Analysis of clones carrying repeated DNA sequences in two YAC
... coordinates of the YAC clones which hybridized to chloroplast DNA with the coordinates of clones which had been mapped previously on to chromosome 4 and the top half of chromosome 5 using RFLP markers as probes (Hwang eta/., 1991; Schmidt etal., unpublished results). One-hundred-and-ninety-five clon ...
... coordinates of the YAC clones which hybridized to chloroplast DNA with the coordinates of clones which had been mapped previously on to chromosome 4 and the top half of chromosome 5 using RFLP markers as probes (Hwang eta/., 1991; Schmidt etal., unpublished results). One-hundred-and-ninety-five clon ...
Fulltext PDF - Indian Academy of Sciences
... methylation pattern acquired in response to abiotic or biotic stress is often inherited over one to several subsequent generations. Cytosine methylation marks affect physiological functions of plants via their effect(s) on gene expression levels. They also repress transposable elements that are abun ...
... methylation pattern acquired in response to abiotic or biotic stress is often inherited over one to several subsequent generations. Cytosine methylation marks affect physiological functions of plants via their effect(s) on gene expression levels. They also repress transposable elements that are abun ...
Assessment by Molecular Dynamics Simulations of the Structural
... binding sites for these transcription factors is greater than is generally acknowledged and not completely understood. A well-studied example of this interplay between related transcription factors within a discrete DNA stretch takes place at the TATA-less promoter of the mdr1 gene,21 which encodes ...
... binding sites for these transcription factors is greater than is generally acknowledged and not completely understood. A well-studied example of this interplay between related transcription factors within a discrete DNA stretch takes place at the TATA-less promoter of the mdr1 gene,21 which encodes ...
Engineered Cpf1 Enzymes with Altered PAM Specificities
... oligonucleotides and HiScribe T7 in vitro Transcription Kit (NEB) following the manufacturer’s recommended protocol. For the PAM library, a degenerate 8 bp sequence preceding a 33 bp target site1 was cloned into the MCS in pUC19, and the library was digested with AatII and LguI and gel extracted pri ...
... oligonucleotides and HiScribe T7 in vitro Transcription Kit (NEB) following the manufacturer’s recommended protocol. For the PAM library, a degenerate 8 bp sequence preceding a 33 bp target site1 was cloned into the MCS in pUC19, and the library was digested with AatII and LguI and gel extracted pri ...
CBSE XII BIO QS with key(2009-2015)
... they have food reserves for the seedling or embryo the seed coat provides protection to the embryo generate genetic variation remain viable for a considerable period of time.(any two) =1x2 State what is apomixis? Comment on its significance. How can it be commercially used? (2015) Form of asexual re ...
... they have food reserves for the seedling or embryo the seed coat provides protection to the embryo generate genetic variation remain viable for a considerable period of time.(any two) =1x2 State what is apomixis? Comment on its significance. How can it be commercially used? (2015) Form of asexual re ...
Graph-based Methods for the Design of DNA - TUBdok
... in order to more accurately assess the performance of a candidate DNA encoding for these models. The evaluation is performed with respect to thermodynamic restrictions and allows to find weak spots in the encoding set of DNA words. The second issue is the prediction of the hybridization energy for a ...
... in order to more accurately assess the performance of a candidate DNA encoding for these models. The evaluation is performed with respect to thermodynamic restrictions and allows to find weak spots in the encoding set of DNA words. The second issue is the prediction of the hybridization energy for a ...
Press release
... extent on the sample material itself (leaf and seed material, animal tissue, hair, etc.). sbeadex - high-quality DNA preparations The oKtopure utilises the sbeadexTM extraction chemistry developed by LGC, which is based on the use of magnetic particles. These particles can specifically bind nucleic ...
... extent on the sample material itself (leaf and seed material, animal tissue, hair, etc.). sbeadex - high-quality DNA preparations The oKtopure utilises the sbeadexTM extraction chemistry developed by LGC, which is based on the use of magnetic particles. These particles can specifically bind nucleic ...
Defining characteristics of Tn5 Transposase non
... While non-specific DNA plays a role in target localization for many recombinases, transcription factors and restriction enzymes, the importance of nonspecific DNA interactions for transposases has not been investigated. Here, we discuss non-specific DNA-Tn5 Transposase (Tnp) interactions and suggest ...
... While non-specific DNA plays a role in target localization for many recombinases, transcription factors and restriction enzymes, the importance of nonspecific DNA interactions for transposases has not been investigated. Here, we discuss non-specific DNA-Tn5 Transposase (Tnp) interactions and suggest ...
Introduction - bei DuEPublico
... that proliferates without control and colonizes territories normally reserved for other cells. The tumour that is formed in consequence of proliferation of neoplastic cells is a growing mass without any function for the organism as a whole. As long as the neoplastic cells remain clustered together i ...
... that proliferates without control and colonizes territories normally reserved for other cells. The tumour that is formed in consequence of proliferation of neoplastic cells is a growing mass without any function for the organism as a whole. As long as the neoplastic cells remain clustered together i ...