Gastrointestinal Disorders: Nausea in Adults
... pregnant women experience varying degrees of nausea and vomiting, usually in the first 16 weeks of pregnancy. NVP can occur throughout the day despite the common expression “morning sickness.” Less than 2% of pregnant patients go on to hyperemesis gravidarum, which may require hospitalization and in ...
... pregnant women experience varying degrees of nausea and vomiting, usually in the first 16 weeks of pregnancy. NVP can occur throughout the day despite the common expression “morning sickness.” Less than 2% of pregnant patients go on to hyperemesis gravidarum, which may require hospitalization and in ...
Hatch-Waxman Turns 30 - Yale Law School Legal Scholarship
... Waxman was also a boon to the brand-name drug industry by providing market exclusivity extensions, which translated into billions of dollars in additional revenue. Since Hatch-Waxman, transformative drugs brought to market based in part on investment by brand-name drug companies have offered advance ...
... Waxman was also a boon to the brand-name drug industry by providing market exclusivity extensions, which translated into billions of dollars in additional revenue. Since Hatch-Waxman, transformative drugs brought to market based in part on investment by brand-name drug companies have offered advance ...
Hyoscyamine Sulfate Extended-Release Tablets, USP 0.375 mg
... biliary and renal colic; as a “drying agent” in the relief of symptoms of acute rhinitis; in the therapy of parkinsonism to reduce rigidity and tremors and to control associated sialorrhea and hyperhidrosis. May be used in the therapy of poisoning by anticholinesterase agents. ...
... biliary and renal colic; as a “drying agent” in the relief of symptoms of acute rhinitis; in the therapy of parkinsonism to reduce rigidity and tremors and to control associated sialorrhea and hyperhidrosis. May be used in the therapy of poisoning by anticholinesterase agents. ...
Outcome Measures - Multidisciplinary Association for Psychedelic
... also not a scheduled drug, will be conducted by John Harrison for a Psy.D. at the California Institute in Integral Studies. Baseline data will be gathered pre-treatment at the Iboga Therapy House with follow-up data gathered for one year, post-treatment. Follow-up data will be gathered by telephone, ...
... also not a scheduled drug, will be conducted by John Harrison for a Psy.D. at the California Institute in Integral Studies. Baseline data will be gathered pre-treatment at the Iboga Therapy House with follow-up data gathered for one year, post-treatment. Follow-up data will be gathered by telephone, ...
Long-term lorazepam use in elderly psychiatric outpatients
... Tufts University School of Medicine, Boston, MA, USA ...
... Tufts University School of Medicine, Boston, MA, USA ...
Drug abuse treatment as an HIV prevention strategy
... (Auerbach et al., 1994). Other services can also be useful: For example, many programs have begun to offer primary medical care in drug abuse treatment (Selwyn et al., 1989; O’Connor et al., 1994). The recent development of HIV protease inhibitors adds optimism that HIV-infected people can postpone ...
... (Auerbach et al., 1994). Other services can also be useful: For example, many programs have begun to offer primary medical care in drug abuse treatment (Selwyn et al., 1989; O’Connor et al., 1994). The recent development of HIV protease inhibitors adds optimism that HIV-infected people can postpone ...
Ion channel regulators for the treatment of cystic fibrosis
... Miglustat is thus an example of the second type of correctors, a molecule that interacts with the ER chaperone calnexin. A pilot trial in patients with CF is reported in [103] , but the results are not available. Class 3 ‘gating’ mutations are rare. The most common class 3 mutation G551D occurs in ...
... Miglustat is thus an example of the second type of correctors, a molecule that interacts with the ER chaperone calnexin. A pilot trial in patients with CF is reported in [103] , but the results are not available. Class 3 ‘gating’ mutations are rare. The most common class 3 mutation G551D occurs in ...
C 1 G
... The generation of pure metabolites can be achieved by organic synthesis, electrochemical oxidation of the parent drug or by biocatalysis using appropriate enzymes. The synthesis by organic chemistry is often complicated by the lack of appropriate synthetic routes for specific metabolites and may yie ...
... The generation of pure metabolites can be achieved by organic synthesis, electrochemical oxidation of the parent drug or by biocatalysis using appropriate enzymes. The synthesis by organic chemistry is often complicated by the lack of appropriate synthetic routes for specific metabolites and may yie ...
Protocol S1.
... On Zanzibar, multiple studies on the efficacy of mebendazole, albendazole, ivermectin and albendazole plus ivermectin have been conducted (18-20, 45, 46, 48, 50, 51). Actively assessed, no severe side effects were recorded for albendazole or ivermectin in a trial conducted in Unguja in 1994, and mil ...
... On Zanzibar, multiple studies on the efficacy of mebendazole, albendazole, ivermectin and albendazole plus ivermectin have been conducted (18-20, 45, 46, 48, 50, 51). Actively assessed, no severe side effects were recorded for albendazole or ivermectin in a trial conducted in Unguja in 1994, and mil ...
Pharmaceutical Marketing: A Comparison of Different
... Patient Information Leaflet is a document provided along with a prescription medication to provide additional information about that drug. The first information that‟s listed is usually the brand name, the quantities of the drug available and generic name of the product. The other sections are as fo ...
... Patient Information Leaflet is a document provided along with a prescription medication to provide additional information about that drug. The first information that‟s listed is usually the brand name, the quantities of the drug available and generic name of the product. The other sections are as fo ...
Product Monograph - Ask Novartis Pharma
... There is concern on theoretical grounds that patients with aortic stenosis might be at a particular risk of decreased coronary perfusion when treated with vasodilators, because they do not develop as much after load reduction. Dual Blockade of the Renin-Angiotensin System (RAS) There is evidence tha ...
... There is concern on theoretical grounds that patients with aortic stenosis might be at a particular risk of decreased coronary perfusion when treated with vasodilators, because they do not develop as much after load reduction. Dual Blockade of the Renin-Angiotensin System (RAS) There is evidence tha ...
AuspAR: Cabazitaxel - Therapeutic Goods Administration
... Cabazitaxel exhibited a broad spectrum of in vivo antitumour activity, not only in docetaxel sensitive tumour models, but also in tumour models in which docetaxel was poorly or not active. In addition, this compound was found to penetrate the blood brain barrier and marked antitumor activity was obt ...
... Cabazitaxel exhibited a broad spectrum of in vivo antitumour activity, not only in docetaxel sensitive tumour models, but also in tumour models in which docetaxel was poorly or not active. In addition, this compound was found to penetrate the blood brain barrier and marked antitumor activity was obt ...
An evaluation of the anti-inflammatory activity auranofin
... (RA). Although the drug has been successful in treating the symptoms of RA, many patients discontinue its use due to severe toxicity over long periods of continued treatment. Since the introduction of auranofin in 1985 there has been no new clinically approved gold drug. Drug discovery research is d ...
... (RA). Although the drug has been successful in treating the symptoms of RA, many patients discontinue its use due to severe toxicity over long periods of continued treatment. Since the introduction of auranofin in 1985 there has been no new clinically approved gold drug. Drug discovery research is d ...
Report of the WHO Informal Consultation on the use of Praziquantel
... eggs trapped in the tissues. End organ morbidity was thought to develop slowly, but more recent research suggests that this process occurs faster in regions of high infection intensity and in relation to an individual's genetic make up (Ross et al., 2002). Pregnant and lactating women are as suscept ...
... eggs trapped in the tissues. End organ morbidity was thought to develop slowly, but more recent research suggests that this process occurs faster in regions of high infection intensity and in relation to an individual's genetic make up (Ross et al., 2002). Pregnant and lactating women are as suscept ...
Management of Hyperglycemia in Type 2 Diabetes, 2015: A Patient
... diabetes. However, this should always be in the context of a comprehensive cardiovascular risk factor reduction program, to include smoking cessation and the adoption of other healthy lifestyle habits, blood pressure control, lipid management with priority to statin medications, and, in some circums ...
... diabetes. However, this should always be in the context of a comprehensive cardiovascular risk factor reduction program, to include smoking cessation and the adoption of other healthy lifestyle habits, blood pressure control, lipid management with priority to statin medications, and, in some circums ...
The Transforming Growth Factor- Pathway Is a Common
... committee of the Schepens Eye Research Institute. Male Sprague-Dawley rats (5 weeks of age; Taconic Farms, Hudson, NY) were randomly assigned to one of the following groups: control, diabetic, diabetic treated with sorbinil (65 mg 䡠 kg⫺1 䡠 day⫺1; gift of Pfizer, Groton, CT), and diabetic treated wit ...
... committee of the Schepens Eye Research Institute. Male Sprague-Dawley rats (5 weeks of age; Taconic Farms, Hudson, NY) were randomly assigned to one of the following groups: control, diabetic, diabetic treated with sorbinil (65 mg 䡠 kg⫺1 䡠 day⫺1; gift of Pfizer, Groton, CT), and diabetic treated wit ...
Efficacy and Safety of As-Needed, Post Bedtime Dosing with
... A PREVALENCE OF 10-15%.1 RELATIVELY FEW epidemiologic studies are available which provide data on the proportion of patients with specific clinical subtypes of insomnia such as difficulty with sleep onset, difficulty maintaining sleep, or more than one insomnia complaint. Ohayon and Roth, in a large (N ...
... A PREVALENCE OF 10-15%.1 RELATIVELY FEW epidemiologic studies are available which provide data on the proportion of patients with specific clinical subtypes of insomnia such as difficulty with sleep onset, difficulty maintaining sleep, or more than one insomnia complaint. Ohayon and Roth, in a large (N ...
Fragment-Based Drug Discovery Applied to Hsp90
... conformational stability, maturation, and function of other substrate proteins, which are known as clients.1 Heat shock protein 90 (Hsp90a) is a molecular chaperone, and many of its clients are oncology targets that are known to play critical roles in cancer progression.2,3 In fact it has been argue ...
... conformational stability, maturation, and function of other substrate proteins, which are known as clients.1 Heat shock protein 90 (Hsp90a) is a molecular chaperone, and many of its clients are oncology targets that are known to play critical roles in cancer progression.2,3 In fact it has been argue ...
Bioburden Control of Non-sterile Drug Substances and Products
... • Any environmental monitoring program would be risk based in terms of sample selection and risk‐based in terms of sample selection and frequency and would be used to confirm microbial control and would not be linked to product release. control and would not be linked to product release. August 4 ...
... • Any environmental monitoring program would be risk based in terms of sample selection and risk‐based in terms of sample selection and frequency and would be used to confirm microbial control and would not be linked to product release. control and would not be linked to product release. August 4 ...
Differential Influences of Ethanol on Early Exposure to Racemic
... 10- and 5-mg tablets (Ritalin), and the 5-mg tablets cut to the nearest 2.5 mg using a tablet cutter as appropriate; d-MPH with or without ethanol, using oral immediate-release d-MPH hydrochloride (0.15 mg/kg) administered as 5- and 2.5-mg tablets (Focalin; Novartis Pharmaceuticals, Summit, NJ), and ...
... 10- and 5-mg tablets (Ritalin), and the 5-mg tablets cut to the nearest 2.5 mg using a tablet cutter as appropriate; d-MPH with or without ethanol, using oral immediate-release d-MPH hydrochloride (0.15 mg/kg) administered as 5- and 2.5-mg tablets (Focalin; Novartis Pharmaceuticals, Summit, NJ), and ...
(Soma): prescribing indications
... sedative properties and may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a motor vehicle or operating machinery. Drug Dependence, Withdrawal and Abuse - In postmarketing experience, cases of drug abuse, dependence and withdra ...
... sedative properties and may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving a motor vehicle or operating machinery. Drug Dependence, Withdrawal and Abuse - In postmarketing experience, cases of drug abuse, dependence and withdra ...
UV SPECTROPHOTOMETRIC METHOD FOR DETERMINATION OF ONDANSETRON
... A simple, rapid, precise, accurate and sensitive analytical method was developed for the UV spectrophotometric assay of ondansetron. The drug obeyed the Beer’s law and showed good correlation. It showed absorption maxima at 248 nm in saline. The linearity was observed between 5 – 25 µg mL-1. The res ...
... A simple, rapid, precise, accurate and sensitive analytical method was developed for the UV spectrophotometric assay of ondansetron. The drug obeyed the Beer’s law and showed good correlation. It showed absorption maxima at 248 nm in saline. The linearity was observed between 5 – 25 µg mL-1. The res ...
Sulfamethoxazole / Trimethoprim Sulfamethoxazole / Trimethoprim
... effects have occurred in up to 80% of AIDS patients receiving the drug but generally have been reversible following discontinuation of SMX-TMP therapy. Glutathione deficiency in HIV infected patients and the resultant accumulation of reactive hydroxylamine metabolites of sulfamethoxazole may be invo ...
... effects have occurred in up to 80% of AIDS patients receiving the drug but generally have been reversible following discontinuation of SMX-TMP therapy. Glutathione deficiency in HIV infected patients and the resultant accumulation of reactive hydroxylamine metabolites of sulfamethoxazole may be invo ...