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Parkinson`s Disease
Parkinson`s Disease

... Age. Young adults rarely experience Parkinson's disease. It ordinarily begins in middle or late life, and the risk increases with age. People usually develop the disease around age 60 or older.  Heredity. Having a close relative with Parkinson's disease increases the chances that you'll develop the ...
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... as a result of the adaptation (tolerance) produced by a resetting of homeostatic mechanisms in response to repeated drug use. Psychological dependence is manifested by compulsive drug seeking behavior in which the individual uses the drug repetitively for personal satisfaction often in the face of k ...
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... -Lecture 5Function Target Tubulin and it’s an anti cancer drug. Target Tubulin and used to treat gout. The drug competes reversibly with the natural substrate (ACH) for the enzyme (cholinesterase at MEP). The drug competes irreversibly with the natural substrate (ACH) for the enzyme (cholinesterase) ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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