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Pharmacogenomics: The Future of Personalized Medicine
Pharmacogenomics: The Future of Personalized Medicine

... What does it mean for patients?  Ideally, genomics would optimize drug therapy for patients based on prescribing medication that would deliver the best results based on the patient’s genotype, while minimizing the adverse ...
paperless tailored lower risk cost efficient
paperless tailored lower risk cost efficient

... procedures, and adopt standard protocols for their administration. It comprises two fundamental parts: ...
USMLE I
USMLE I

... imprisoned and is not able to obtain the drug. He is brought to the prison medical ward because of the onset of severe anxiety, increased sensitivity to light, dizziness, and generalized tremors. On physical examination, he is hyperreflexic. Which of the fol- lowing agents should he be given to dimi ...
Dear Parents of A Smith, Your child currently has a final 9
Dear Parents of A Smith, Your child currently has a final 9

... b. MOA for prevention of migraine no fully understood- may stabilize seroternergic neurotransmission by anatagonizing down regulation of 5-HT2 receptors c. Examples i. Selective serotonin reuptake inhibitors (SSRI) (Prozac and others) 1. More efficacious with migraines associated with depression- in ...
FOOD-Drug Interactions (FDI)
FOOD-Drug Interactions (FDI)

... Role of pharmacist in preventing food-drug interaction  Vigilant in monitoring for potential drug-food interactions  Advising patients regarding foods or beverages to avoid when taking certain medications  Pharmacists to keep upto-date on potential drug-food interactions of medications ...
Syllabus - University of Minnesota College of Pharmacy
Syllabus - University of Minnesota College of Pharmacy

Drug trace evidence on banknotes Norman Fenton, July 2011
Drug trace evidence on banknotes Norman Fenton, July 2011

... Answer (according to ‘standard’ approaches): Yes, as there is a less than 1% chance that a randomly selected note in the possession of a non drug user/dealer will have more than 55 units of cocaine. ...
What is a “zebrafish”? - Charles R. Drew University of Medicine and
What is a “zebrafish”? - Charles R. Drew University of Medicine and

... placed into single wells of a multi well plate • Multi-plate illuminated from below with a 15w lightbox • Larvae given 5 minutes to ...
AP - Intec Pharma
AP - Intec Pharma

... unanticipated events, except as required by applicable law. In evaluating forward-looking statements, you should consider these risks and uncertainties. ...
1 - A patient allergic to penicillin group of antibiotics has to avoid
1 - A patient allergic to penicillin group of antibiotics has to avoid

... 75-The time of peak serum concentration gives indication of the relative rate of: a. absorption d- elimination b. distribution e. biotransformation c. metabolism 76-The area under the serum concentration vs. time curve (AUC) represents the: a. biologic half-time of the drug b. amount of the drug th ...
Cancer Chemotherapy-2
Cancer Chemotherapy-2

...  L-Asparaginase is used in combination therapy to treat childhood acute lymphocytic leukemia  Its mechanism of action is based on the fact that some neoplastic cells require an external source of asparagine because of their limited capacity to synthesize sufficient amounts of that amino acid to su ...
FUN2: 11:00-12:00 Scribe: Taylor Nelson Wednesday, December
FUN2: 11:00-12:00 Scribe: Taylor Nelson Wednesday, December

... i. The use of the term indirect is the same as the use for the term Cholinergic stimulus ii. These compounds produce their effects by releasing NE from the nerve terminals iii. They do not inhibit an enzyme iv. The best example, with a major indirect mechanism of action is amphetamine and its variou ...
CTSN graduate student Kara Kittelberger
CTSN graduate student Kara Kittelberger

... social deficits characteristic of these psychiatric diseases. The oxytocin system plays a well-known role in social behavior in both humans and model animals, including the monogamous prairie vole. The recent discovery of a novel mechanism of stimulating central oxytocin release through the use of a ...
Herbal Remedies and Drug Interactions
Herbal Remedies and Drug Interactions

... now market any herbal or botanical product without prior approval by the FDA as long as the label does not claim effectiveness for the treatment or prevention of a specific disease.  Must have a disclaimer stating that the FDA has not evaluated the product. ...
substance abuse - Molloy College
substance abuse - Molloy College

... treatment followed by long-term outpatient care and support (aftercare). • Encourage teen to begin an open discussion with parents, school guidance, counselor, or other trusted adult about sex, drugs, depression, or other concerns. • Continue to educate teens about the negatives of drugs use with ea ...
Neurology Firm NuPathe Gets $15M For Lead Migraine Patch
Neurology Firm NuPathe Gets $15M For Lead Migraine Patch

... million in a Series A round enough to take the young firm to a regulatory filing within two years. “It’s our first big venture round. We’ve only had seed financing before, so this is a critical raise for us,” said Jane Hollingsworth, the company’s CEO. Hollingsworth and her colleague, Terri Sebree, ...
Urine drug screening Urine drug screens
Urine drug screening Urine drug screens

... A negative UDS does not necessarily mean the patient is diverting their drugs. It may be because the patient’s drug level was below threshold due to dose and dosing, especially if the patient is very well hydrated. A good practice is to ask when the last dose was taken when obtaining a UDS. Drug met ...
Absorption, distribution, metabolism and excretion
Absorption, distribution, metabolism and excretion

... contd. c. Pinocytosis: It involves  invagination of part of the cell membrane and the trapping of a small vesicle containing extracellular constituents within the cell  The vesicle contents can then be released within the cell, or extruded from its other side  Examples:  Pinocytosis of vitamin B ...
Patients medical history is reviewed prior to administering drugs and
Patients medical history is reviewed prior to administering drugs and

... Acepromazine is used to facilitate restraint of patients. It has anti emetic, anti spasmodic and hypothermic properties. Adverse and Common Side effects- Following side effects have been noted with use of acepromazine: constipation, paradoxical aggression, sinus bradycardia, depression of my contrac ...
rohypnol – flunitrazepam – (roofies)
rohypnol – flunitrazepam – (roofies)

... judgment and impaired motor skills and can make a victim unable to resist a sexual attack. The combination of alcohol and Rohypnol is also particularly hazardous because together, their effects on memory and judgment are greater than the effects resulting from either taken alone. Effects begin withi ...
Patient Education LORAZEPAM
Patient Education LORAZEPAM

... COMMON BRAND NAME(S): Ativan USES: Lorazepam is used to treat anxiety. OTHER USES: This drug may also be used for seizures, alcohol withdrawal, prevention of nausea and vomiting due to chemotherapy, tension headache, and for sleeping trouble (insomnia). HOW TO USE: Take as directed. The dose and fre ...
File - Ms. Ward`s class!
File - Ms. Ward`s class!

... By Mouth, Oral (PO): The major benefit of oral administration is the convenience to the patient. -Oral medications are systemic (work throughout the body) -Safer, because they take time to work and therefore an antidote can be given if overdosed. -However, these drugs do not work as quickly ...
SedaLin - Xymogen
SedaLin - Xymogen

... Magnolia officinalis Magnolia bark is rich in a biphenol compound called honokiol and its isomer magnolol. In experimental animal studies, these compounds have been shown to enhance the activity of gamma-aminobutyric acid (GABA) A receptors and GABA binding, *These statements have not been evaluated ...
Injectable Anesthetics
Injectable Anesthetics

... a conscious animal the respiratory center responds to rising levels of CO2 in arterial blood (PaCO2) These chemoreceptors are in the aortic arch and the carotid sinus (bifurcation of the carotid arteries) They sense the increase in CO2 levels and send the impulse to muscles to breathe ...
Action - جامعة الكوفة
Action - جامعة الكوفة

... - Ach storage into vesicles. -Release of ACh from vesicles in the nerve ending requires the entry of calcium through calcium channels and triggering of interaction between several proteins associated with the vesicles and the nerve ending membrane. This interaction results in the fusion of the vescu ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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