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ANXIOLYTICS AND HYPNOTICS
ANXIOLYTICS AND HYPNOTICS

...  Benzodiazepines relieve anxiety through enhancement of the inhibitory activity of ...
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sample-2 - Philadelphia University Jordan

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Toxicology Drugs
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... activate corticotropin-releasing factor, a brain chemical that increases during periods of stress. Consequently, Koob says, this could "lead to a subtle disruption of brain processes that are then 'primed' for further and easier disruption by other drugs of abuse." George ...
Review Notes Chapter 24: Alcohol, Tobacco, and Other Drug
Review Notes Chapter 24: Alcohol, Tobacco, and Other Drug

... it. Tolerance and physical dependence develop quickly. Cross-tolerance to other opioids can occur. Chronic abuse of opioids causes few physiological problems except for constipation. The negative consequences primarily result from the drug’s illegal status. B. Stimulants. These drugs make people fee ...
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... • a further burst of acetylcholine from the nerve terminal cannot produce depolarisation of end plate due to the still presence of succinylcholine at the end plate and can not overcome the inactivated state of Na+ channel in perijunctional area due to continuous depolarisation of end plate. • So, ne ...
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Dopamine receptor agonist treatment of Parkinson`s disease

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... the chemicals in the food and drugs we digest. 2. How does a drug change when it enters the body?  When a drug enters the liver, special proteins called enzymes bind to the drug and break it down. Enzymes break down a drug to either dispose of it or react with it to produce an effect in the body.  ...
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... are directly related to the progressive degeneration of primarily brain dopamine (DA) neurons. No disease modifying drugs have yet been developed for PD and various symptomatic drugs are currently used to treat the motor symptoms of the disease. These drugs include DA receptor agonists, MAO inhibito ...
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... procedure. Six tiny holes were made in the skull of each subject, and then a liquid containing the healthy CLN2 gene, within the harmless adeno-associated virus (AAV), was injected into the brain. "Before now, we had no hope of a therapy for Batten disease, but today we can say that there is some ho ...
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Clinical Trial Update

... Actinogen Medical expects this final cohort to be dosed in late April and is pleased to reaffirm that the clinical trial program continues to execute on time and on budget. This stage of the trial will be complete with the successful dosing of the third cohort of 8 participants at 35mg. The next sta ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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