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DSST® SUBSTANCE ABUSE
DSST® SUBSTANCE ABUSE

... title at the time the test was developed. You may reference either the current edition of these titles or textbooks currently used at a local college or university for the same class title. It is recommended that you reference more than one textbook on the topics outlined in this fact sheet. You sho ...
Pharmacology
Pharmacology

... contact with drug. A direct action at one part can at times elicit effects on remote organs or tissues, which are designated as indirect action. ...
Cushings disease - The Acorns Equine Clinic
Cushings disease - The Acorns Equine Clinic

... Pituitary Gland. The Pituitary Gland produces several different hormones including one called ACTH this acts on the Adrenal Glands (near the kidneys). These glands are in turn stimulated to produce Cortisol (a natural steroid). Cortisol has many functions including water regulation, sugar distributi ...
heroin - a case
heroin - a case

... Number of people found guilty or cautioned by police for drug offences rose from – 44 922 in 1990 – To 120 007 in 1999 ...
CPP-109 Clinical Trial Data to be Presented at the American Society
CPP-109 Clinical Trial Data to be Presented at the American Society

... effective treatment and which demonstrates the potential to address an unmet medical need. Catalyst also expects to evaluate CPP-109 for the treatment of other addictions and obsessive-compulsive disorders. Catalyst is also in the early stages of developing CPP-115, another GABA aminotransferase inh ...
Neuro, References
Neuro, References

... • COMT inhibitors - adjunct that extends the action of levodopa/carbidopa; (a) Tolcapone (Tasmar), monitor hepatic function, and (b) entacapone (Comtan) ---no monotherapy • MAO-B inhibitor-adjunct that decreases breakdown of dopamine; (a) selegiline (Eldepryl, Emsam, Zelapar), (b) rasagiline (Azilec ...
Huntington`s disease
Huntington`s disease

ocena dokumentacji chemicznej, farmaceutycznej i biologicznej
ocena dokumentacji chemicznej, farmaceutycznej i biologicznej

... A formal interaction study investigating the potential of drug interaction between nitrendipine and anticonvulsants has not been performed. However, phenytoin, phenobarbitone and carbamazepine are known as potential inducers of the cytochrome P450 3A4 system. Furthermore, concomitant administration ...
Drug Discovery and Development
Drug Discovery and Development

... • In the past, many medicines (and lead compounds) were isolated from plant sources. • Since plants did not evolve with human beings in mind, the fact that they posses chemicals which results in effects on humans is incidental. ...
Bacteria and mycobacteria
Bacteria and mycobacteria

... • The interior of the cell has a high osmotic pressure. • If the bacterial cell wall is not intact, the internal osmotic pressure draws fluid into the cell until it bursts. • Even when the cell wall is breached by an antibiotic, bacterial death may not occur because of bacterial resistance. ...
+ Alcohol Dependence and Abuse
+ Alcohol Dependence and Abuse

... cigarette) activate the reward and pleasure areas of the brain involved in drug use. ...
Medication Use in the Elderly
Medication Use in the Elderly

... Drugs with a narrower therapeutic index (e.g., digoxin, cimetidine, aminoglycosides), side effects in older patients if dose reductions are not made . Digoxin is the drug that most often causes side effects in the elderly, especially if the dose exceeds 0.125 mg daily ...
Catabasis ACS Conference Presentation 11aug2015 FINAL
Catabasis ACS Conference Presentation 11aug2015 FINAL

... muscle health. In skeletal muscle, activated NF-kB drives muscle degeneration and suppresses muscle regeneration. In animal models of DMD, CAT-1004 inhibited activated NF-kB, reduced muscle inflammation and degeneration and increased muscle regeneration. In Phase 1 clinical trials, CAT-1004 inhibite ...
FileList Convert a pdf file!
FileList Convert a pdf file!

Drug-induced sleepiness and insomnia: an update
Drug-induced sleepiness and insomnia: an update

... intentionally used due to their effects on sleep, grouping them according to the diseases for which they are recommended, and we will describe their potential to induce sleepiness or insomnia in more detail. For drugs without such potential, we will only cite them as not possessing either property; ...
2 receptor
2 receptor

... - beta2 receptors can increase NE release Presynaptic heteroreceptors can modulate NE release - ACh can reduce NE release Tyrosine hydroxylase activity increases or decreases to maintain steady-state levels of norepinephrine. ...
Neuro Nursing - HarvardNeurosurgeon.com
Neuro Nursing - HarvardNeurosurgeon.com

... Intro to Parkinson’s Disease (PD) • Degenerative Disease in which the cells of the substantia nigra (part of the brainstem) die & stop making dopamine for an unknown reason. • The loss of dopamine unleashes a cascade of events which causes resting tremor, stiffness, slowed movements, and walking pr ...
Table of Antidotes (Word Document, 20kB)
Table of Antidotes (Word Document, 20kB)

... Amyl nitrite is the first step in a three-step treatment protocol for cyanide poisoning. After the administration of amyl nitrite, administer sodium nitrite, followed by sodium ...
DRUG INTERACTIONS
DRUG INTERACTIONS

... capsules/day, 14 days). Each GT capsule contained 211 +/- 25 mg of catechins and <1 mg of caffeine against 30 mg dextromethorphan (CYP 2D6 activity) and 2 mg alprazolam (CYP 3A4 activity) did not affect elimination of the two drugs in 11 human volunteers ...
File - Riske Science
File - Riske Science

... Drug Dosing Regimes • The dosing regime for a drug refers to the specific quantity of drug to be taken at one time, and the frequency of administration. • Calculations of dosage must take bioavailability into account, as well as possible side-effects and potential problems of tolerance and addictio ...
PATIENT`S NAME: MEDICATION: famotidine (Brand names include
PATIENT`S NAME: MEDICATION: famotidine (Brand names include

... reactions. Notify your prescriber if any of these symptoms become bothersome. INTERACTIONS Although famotidine may not interact with others drugs, you should avoid alcohol and caffeine when taking it because they may increase gastric irritation. Don’t use herbal remedies without consulting your pres ...
Antidepressiva werken niet
Antidepressiva werken niet

... therapies, which ministers see as a better alternative to drugs. Patients are strongly advised not to stop taking their medication without first consulting a doctor. The researchers accept many people believe the drugs do work for them, but argue that could be a placebo effect - people feel better s ...
Learning About Drugs and Alcohol Through Biotechnology
Learning About Drugs and Alcohol Through Biotechnology

... spreading through the dopamine pathway. (See previous article.) By an accident of nature, the cocaine molecule is similar to dopamine, so dopamine neurons attract cocaine like a magnet. Cocaine fits into the transporter pump, which normally pumps dopamine out of the gap between neurons and quiets do ...
HEMATEMESIS AND GI BLOOD LOSS Michael D Willard
HEMATEMESIS AND GI BLOOD LOSS Michael D Willard

... surgery, and endoscopy usually allows one to easily find all areas of ulceration. Sometimes intraoperative endoscopy is necessary to help the surgeon find the ulcer(s). If medical management is elected, first be sure to remove the cause of the GUE. If the cause is not removed, medical management ten ...
Prograf® (tacrolimus)
Prograf® (tacrolimus)

... blood pressure dropped. After infectious, cardiac, and neurological causes of hypotension were ruled out, a cosyntropin stimulation test, was performed to exclude adrenal insufficiency. ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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